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191 Results Found

  • Article
  • Open Access
40 Citations
8,248 Views
12 Pages

Association of Uric Acid with Metabolic Syndrome in Men, Premenopausal Women and Postmenopausal Women

  • Yongqiang Li,
  • Shanying Chen,
  • Xiaofei Shao,
  • Jia Guo,
  • Xinyu Liu,
  • Aiqun Liu,
  • Ying Zhang,
  • Honglei Wang,
  • Bin Li and
  • Hequn Zou
  • + 2 authors

Objective: To explore the relationship between serum uric acid (SUA) and metabolic syndrome (MS) in men, premenopausal women and postmenopausal women. Methods: A cross-sectional study was conducted in 1,834 community-based Southern Chinese participan...

  • Article
  • Open Access
27 Citations
6,786 Views
10 Pages

It is well known that plasma lipids, waist circumference (WC) and blood pressure (BP) increase following menopause. In addition, there is a perceived notion that plasma high-density lipoprotein-cholesterol (HDL-C) concentrations also decrease in post...

  • Feature Paper
  • Article
  • Open Access
1 Citations
2,666 Views
12 Pages

Association of Serum Uric Acid with Diabetes in Premenopausal and Postmenopausal Women—A Prospective Cohort Study in Shanghai, China

  • Qian Wu,
  • Ying Guan,
  • Chunze Xu,
  • Na Wang,
  • Xing Liu,
  • Feng Jiang,
  • Qi Zhao,
  • Zhongxing Sun,
  • Genming Zhao and
  • Yonggen Jiang

There have been few prospective studies on the association between serum uric acid (SUA) and the risk of diabetes in women, and there have been few large-scale Chinese studies based on menopause to investigate the association. Therefore, the present...

  • Article
  • Open Access
4,889 Views
21 Pages

Background: Recurrent urinary tract infections (rUTIs) significantly impair women’s quality of life, making antimicrobial prophylaxis a critical preventative strategy. This retrospective observational study aimed to characterize antibiotic prop...

  • Abstract
  • Open Access
1,369 Views
2 Pages

Assessment of Vitamin D Intake and Status in Slovenian Premenopausal and Postmenopausal Women

  • Vid Vičič,
  • Petra Pavlič,
  • Valentina Rok,
  • Saša Kugler,
  • Andreja Kukec and
  • Ruža Pandel Mikuš

Background and objective: The main source of Vitamin D is the synthesis of cholecalciferol (D3) from 7-dehydrocholesterol in the skin when exposed to ultraviolet radiation. A significant intake can be obtained from supplementation and fortified foods...

  • Systematic Review
  • Open Access
33 Citations
13,084 Views
21 Pages

29 December 2021

Dehydroepiandrosterone (DHEA), and its metabolite, dehydroepiandrosterone sulfate ester (DHEAS), are the most abundant circulating steroid hormones, and are synthesized in the zona reticularis of the adrenal cortex, in the gonads, and in the brain. T...

  • Article
  • Open Access
3 Citations
2,521 Views
21 Pages

Background: no studies have assessed the associations of nutrient intake, physical activity, age, and body mass index (BMI) with bone mineral density (BMD) using structural equation modelling (SEM) in Korean women. The aim of this study was to examin...

  • Article
  • Open Access
1,375 Views
15 Pages

Trends in the Incidence of Ovarian Cancer Among Premenopausal and Postmenopausal Women in the United States, 2001 to 2021

  • Victor Adekanmbi,
  • Abbey B. Berenson,
  • Batul Shakir,
  • Christine D. Hsu,
  • Thao N. Hoang,
  • Itunu O. Sokale,
  • Tolulope T. Sajobi and
  • Fangjian Guo

24 June 2025

Background: Ovarian cancer remains the deadliest and leading cause of gynecological cancer-associated mortality in the US. The aim of this study was to characterize the trends in the incidence of ovarian cancer between premenopausal and postmenopausa...

  • Article
  • Open Access
2,016 Views
17 Pages

Targeted Analysis of Plasma Polar Metabolites in Postmenopausal Depression

  • Maria Fernanda Naufel,
  • Amanda Paula Pedroso,
  • Adriana Pereira de Souza,
  • Valter Tadeu Boldarine,
  • Lila Missae Oyama,
  • Edson Guimarães Lo Turco,
  • Helena Hachul,
  • Eliane Beraldi Ribeiro and
  • Mônica Marques Telles

Depression will be the disease with the highest incidence worldwide by 2030. Data indicate that postmenopausal women have a higher incidence of mood disorders, and this high vulnerability seems to be related to hormonal changes and weight gain. Altho...

  • Article
  • Open Access
5 Citations
2,989 Views
12 Pages

16 December 2022

The objective of our study was to evaluate vitamin D status and its predictors in Slovenian premenopausal and postmenopausal women. A cross-sectional study was carried out between 1 March 2021 and 31 May 2021. A total of 319 healthy women from the Ce...

  • Article
  • Open Access
6 Citations
2,810 Views
22 Pages

Trends in Endometrial Cancer Incidence Among Premenopausal and Postmenopausal Women in the United States Between 2001 and 2021

  • Fangjian Guo,
  • Victor Adekanmbi,
  • Christine D. Hsu,
  • Thao N. Hoang,
  • Pamela T. Soliman,
  • Jacques G. Baillargeon and
  • Abbey B. Berenson

20 March 2025

Background: Endometrial cancer incidence has been rising in the United States. We assessed trends in endometrial cancer incidence among both premenopausal and postmenopausal women in the US from 2001 to 2021. We also compared the incidence during 201...

  • Systematic Review
  • Open Access
3 Citations
4,093 Views
9 Pages

Background and Objectives: Vaginitis causes vulvovaginal symptoms, including itching, irritation, vaginal discharge, burning, or foul odor. It is one of the most common diseases encountered in gynecologic practice. Hypoestrogenism due to menopause ha...

  • Article
  • Open Access
6 Citations
3,121 Views
10 Pages

Background: Studies have assessed the effects of menstrual irregularities and menopause on diabetes, but no definitive conclusion has been reached. This study investigated for the first time the relationship between menstrual irregularity and diabete...

  • Article
  • Open Access
4 Citations
3,331 Views
10 Pages

17 May 2021

Osteoporosis is a major public health concern, especially in women. This study aims to identify early biomarkers from biochemical measurements of serum and urine for recognizing the development of osteoporosis and osteopenia in premenopausal and post...

  • Article
  • Open Access
9 Citations
5,185 Views
19 Pages

The Effect of Ramadan Intermittent Fasting on Food Intake, Anthropometric Indices, and Metabolic Markers among Premenopausal and Postmenopausal Women: A Cross-Sectional Study

  • Nada A. AlZunaidy,
  • Abdulrahman S. Al-Khalifa,
  • Maha H. Alhussain,
  • Mohammed A. Mohammed,
  • Hani A. Alfheeaid,
  • Sami A. Althwab and
  • MoezAlIslam E. Faris

24 June 2023

Background and objectives: Ramadan intermittent fasting (RIF) is a monthlong practice in which Muslims fast during the whole day from sunrise to sunset. During this month, fasting people change their dietary behavior and alter their eating hours from...

  • Article
  • Open Access
15 Citations
3,916 Views
13 Pages

Obesity and Risk of Diabetes Mellitus by Menopausal Status: A Nationwide Cohort Study

  • Han Rim Lee,
  • Jungeun Shin,
  • Kyungdo Han,
  • Jiwon Chang,
  • Su-Min Jeong,
  • Seung Joo Chon,
  • Soo Jung Choi and
  • Dong Wook Shin

6 November 2021

Although both obesity and menopause are associated with increased risk of diabetes mellitus (DM), the association between obesity and DM according to menopausal status remains uncertain. Therefore, we conducted a study to examine the relationship bet...

  • Article
  • Open Access
29 Citations
6,295 Views
12 Pages

Endometrial Cancer in Pre-Menopausal Women and Younger: Risk Factors and Outcome

  • Nurliza Abdol Manap,
  • Beng Kwang Ng,
  • Su Ee Phon,
  • Abdul Kadir Abdul Karim,
  • Pei Shan Lim and
  • Maimunah Fadhil

Endometrial cancer is the sixth most common malignancy in women, and it is known to be a disease among postmenopausal women, but there is rising in the number of endometrial cancers among premenopausal women. This study aims to determine the clinical...

  • Article
  • Open Access
1 Citations
2,845 Views
13 Pages

Non-Alcoholic Fatty Liver Disease and the Risk of Diabetes Mellitus by Menopausal Status: A Nationwide Cohort Study

  • Jungeun Shin,
  • Soo Jung Choi,
  • Han Rim Lee,
  • Kyungdo Han,
  • Jiwon Chang,
  • Su-Min Jeong,
  • Yun-sun Choi,
  • Daeho Lee and
  • Dong Wook Shin

30 March 2022

Background: Non-alcoholic fatty liver disease (NAFLD) is regarded as a risk factor for type 2 diabetes mellitus (DM). Menopausal status also influences T2DM risk, where estrogen is presumed to play a protective role by decreasing insulin resistance....

  • Systematic Review
  • Open Access
1 Citations
2,645 Views
20 Pages

Obesity and Risk of Pre- and Postmenopausal Breast Cancer in Africa: A Systematic Review

  • Najia Mane,
  • Aya Fouqani,
  • Siham Mrah,
  • Majid Omari,
  • Oumnia Bouaddi,
  • Elodie Faure,
  • El Mostafa El Fahime,
  • Sihame Lkhoyaali,
  • Saber Boutayeb and
  • Mohamed Khalis
  • + 2 authors

Background and Aims: Several epidemiological studies have investigated the relationship between anthropometric factors and breast cancer (BC), but the results, particularly for premenopausal BC, remain inconsistent and contradictory. The aim of this...

  • Article
  • Open Access
3 Citations
2,945 Views
12 Pages

The Impact of Sustainable Exercise on Self-Efficacy and Life Satisfaction in Women before and after Menopause

  • Abdulaziz Kulak,
  • Turhan Toros,
  • Emre Bulent Ogras,
  • Ibrahim Efe Etiler,
  • Emre Bagci,
  • Belgin Gokyurek and
  • Ulviye Bilgin

12 September 2023

The study aims at elucidating the association between sustainable exercise and its influence on self-efficacy and life satisfaction in women during their premenopausal and postmenopausal stages. A relational screening model was employed on a sample o...

  • Article
  • Open Access
4 Citations
3,527 Views
12 Pages

Depressive symptoms do not persistently negatively affect functioning throughout the life span, but they may affect quality of life (QOL), especially in middle-aged women. Therefore, this study aimed to investigate the factors associated with depress...

  • Article
  • Open Access
4 Citations
2,666 Views
17 Pages

20 October 2023

Sarcopenia prevalence depends on the definition, and ethnicity must be considered when setting reference values. However, there is no specific cut-off for sarcopenia in Saudi women. Accordingly, we aimed to establish a cut-off value for sarcopenia in...

  • Article
  • Open Access
3,827 Views
12 Pages

Hormone Replacement Therapy Protects Skeletal Muscle by Stabilizing the Neuromuscular Junction in Post-Menopausal Women

  • Maria Abutair,
  • Sara Elkhatib,
  • Rawan Flayyih,
  • Dalal Alarabid,
  • Mohamed Nacer,
  • Rizwan Qaisar,
  • Shah Hussain and
  • Areesha Ashraf

30 October 2024

Introduction: Hormone replacement therapy (HRT) prevents muscle loss associated with menopause; however, the relative role of the neuromuscular junction (NMJ) in post-menopausal women taking HRT is poorly known. We investigate the effects of HRT on p...

  • Article
  • Open Access
11 Citations
4,115 Views
11 Pages

Effect of Resistance Exercise on the Lipolysis Pathway in Obese Pre- and Postmenopausal Women

  • Sunghwun Kang,
  • Kyu-Min Park,
  • Kun-Young Sung,
  • Yuning Yuan and
  • Seung-Taek Lim

31 August 2021

Physical exercise may stimulate lipolytic activity within adipose tissue. Furthermore, resistance exercise may contribute to the more efficient reduction in adipose tissue mass and prevent the accumulation thereof in obese women. The purpose of this...

  • Article
  • Open Access
1 Citations
2,976 Views
13 Pages

Sonographic, Demographic, and Clinical Characteristics of Pre- and Postmenopausal Women with Endometrial Cancer; Results from a Post Hoc Analysis of the IETA4 (International Endometrial Tumor Analysis) Multicenter Cohort

  • Rasmus W. Green,
  • Daniela Fischerová,
  • Antonia C. Testa,
  • Dorella Franchi,
  • Filip Frühauf,
  • Pelle G. Lindqvist,
  • Alessia di Legge,
  • David Cibula,
  • Robert Fruscio and
  • Elisabeth Epstein
  • + 5 authors

In this study, we conducted a comparative analysis of demographic, histopathological, and sonographic characteristics between pre- and postmenopausal women diagnosed with endometrial cancer, while also examining sonographic and anthropometric feature...

  • Article
  • Open Access
22 Citations
5,403 Views
11 Pages

The Importance of Being a ‘Lark’ in Post-Menopausal Women with Obesity: A Ploy to Prevent Type 2 Diabetes Mellitus?

  • Luigi Barrea,
  • Claudia Vetrani,
  • Barbara Altieri,
  • Ludovica Verde,
  • Silvia Savastano,
  • Annamaria Colao and
  • Giovanna Muscogiuri

25 October 2021

Chronotype is defined as the behavioral manifestation of circadian rhythms related to the external light–dark cycle. Evening chronotype has been associated with an increased risk of developing cardiometabolic diseases in obesity. Menopause is a lifes...

  • Article
  • Open Access
28 Citations
8,084 Views
13 Pages

9 May 2022

During their lifetime, 20% of US women experience depression. Studies have indicated that a high Dietary Inflammatory Index (DII) score is associated with high C-reactive protein (CRP) levels and depression. No previous study has compared the associa...

  • Article
  • Open Access
8 Citations
2,615 Views
11 Pages

Diabetes mellitus (DM) is known to lead to many diseases such as cardiovascular disease and chronic kidney diseases. Therefore, it is essential to find diagnostic tools to prevent DM. This study aimed to find the association between handgrip strength...

  • Article
  • Open Access
1,340 Views
17 Pages

Association Between Volatile Organic Compounds and Circadian Syndrome Among Pre- and Postmenopausal Women

  • Xiaoya Sun,
  • Zhenao Zhang,
  • Jingyi Ren,
  • Huanting Pei,
  • Jie Liu,
  • Bowen Yin,
  • Chongyue Zhang,
  • Rui Wen,
  • Simeng Qiao and
  • Yuxia Ma

23 April 2025

Air pollution is closely associated with the development of multiple metabolic diseases. Circadian syndrome (CircS), as an extended concept of metabolic syndrome (MetS), has been proven to be a better predictor of metabolic diseases than MetS. Howeve...

  • Article
  • Open Access
51 Citations
8,353 Views
13 Pages

Systemic Oxidative Stress Is Increased in Postmenopausal Women and Independently Associates with Homocysteine Levels

  • Arno R. Bourgonje,
  • Amaal Eman Abdulle,
  • Areej M. Al-Rawas,
  • Muna Al-Maqbali,
  • Mohsin Al-Saleh,
  • Marvin B. Enriquez,
  • Sultan Al-Siyabi,
  • Khamis Al-Hashmi,
  • Intisar Al-Lawati and
  • Jumana Saleh
  • + 3 authors

Oxidative stress plays a pivotal role in the pathogenesis of cardiovascular diseases (CVD). Postmenopausal women have an increased risk of developing CVD due to decreased estrogen availability, which is accompanied by increased oxidative stress. Seru...

  • Review
  • Open Access
4 Citations
2,464 Views
11 Pages

Hypovitaminosis D and Metabolic Syndrome in Postmenopausal Women

  • Haya Abuhijleh,
  • Dana Alkhatib and
  • Vijay Ganji

14 October 2022

Metabolic syndrome (MetSyn) is a precursor for several cardiometabolic diseases. The prevalence of MetSyn is higher in postmenopausal women compared to premenopausal women. The role of vitamin D in postmenopausal women is not clearly understood. Hypo...

  • Article
  • Open Access
3 Citations
5,010 Views
17 Pages

19 May 2024

The aim of this study was to show for the first time that low-frequency 3D-transmitted ultrasound tomography (3D UT, volography) can differentiate breast tissue types using tissue properties, accurately measure glandular and ductal volumes in vivo, a...

  • Article
  • Open Access
3 Citations
2,650 Views
9 Pages

10 September 2021

The purpose of this study was to investigate bilateral deficit patterns during maximal hand-grip force production in late postmenopausal women. Twenty late postmenopausal and 20 young premenopausal women performed maximal isometric grip force product...

  • Article
  • Open Access
29 Citations
4,628 Views
11 Pages

31 March 2021

Antioxidant intake has been suggested to be associated with a reduced osteoporosis risk, but the effect of dietary total antioxidant capacity (TAC) on bone health and the risk of osteoporosis remains unclear. We aimed to assess the hypothesis that di...

  • Article
  • Open Access
16 Citations
4,829 Views
18 Pages

Consumption of Dairy Products and the Risk of Developing Breast Cancer in Polish Women

  • Bożena Wajszczyk,
  • Jadwiga Charzewska,
  • Dariusz Godlewski,
  • Brunon Zemła,
  • Elżbieta Nowakowska,
  • Maciej Kozaczka,
  • Małgorzata Chilimoniuk and
  • Dorothy R. Pathak

10 December 2021

Lack of consistency in the relationship between dairy products consumption and breast cancer (BC) risk motivated us to evaluate this association in a case-control study of BC among Polish women. The study includes 1699 women 26–79 years of age,...

  • Article
  • Open Access
7 Citations
3,424 Views
11 Pages

25 March 2023

Osteoporosis is a prevalent issue among postmenopausal women, who have a higher incidence of the condition than men. This study aimed to examine the relationship between phytochemical-rich food intake and osteoporosis incidence in premenopausal and p...

  • Article
  • Open Access
3 Citations
3,318 Views
21 Pages

Mitochondrial DNA Polymorphism in HV1 and HV2 Regions and 12S rDNA in Perimenopausal Hypertensive Women

  • Wojciech Kwaśniewski,
  • Aleksandra Stupak,
  • Alicja Warowicka,
  • Anna Goździcka-Józefiak,
  • Jerzy Mosiewicz and
  • Jolanta Mieczkowska

Estrogens enhance cellular mitochondrial activity. The diminution of female hormones during menopause may have an effect on the mitochondrial genome and the expression of mitochondrial proteins. Hence, oxidative stress and the pro-inflammatory state...

  • Correction
  • Open Access
1 Citations
1,311 Views
3 Pages

27 April 2023

In the original publication [...]

  • Article
  • Open Access
23 Citations
4,160 Views
10 Pages

Background: The study investigated the effects of regular leisure-time physical activity on the parameters of cognitive function (plasma brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), and cathepsin B) and menopausal symptoms (th...

  • Article
  • Open Access
18 Citations
3,769 Views
9 Pages

Impact of Menopause and the Menstrual Cycle on Oxidative Stress in Japanese Women

  • Ayaka Ishikawa,
  • Hiroshi Matsushita,
  • Saki Shimizu,
  • Noriko Morita,
  • Rina Hanai,
  • Saeko Sugiyama,
  • Kazushi Watanabe and
  • Akihiko Wakatsuki

20 January 2023

Although estrogen possesses both pro- and anti-oxidant properties, its overall role in oxidative stress among women remains unclear, particularly since the influence of exogenously administered estrogen during previous studies differed by dose, admin...

  • Article
  • Open Access
1,499 Views
13 Pages

12 September 2025

Background/Objectives: This study aimed to investigate the association between dietary patterns and the risk of developing osteoporosis in women, emphasizing the role of nutrition in bone health during menopause-related hormonal changes. Methods: We...

  • Article
  • Open Access
12 Citations
4,275 Views
16 Pages

Background: Triple-negative breast cancer (TNBC) is the most aggressive form of breast cancer, with poor outcomes. The molecular basis of TNBC remains poorly understood. The objective of this exploratory study was to investigate the association betwe...

  • Article
  • Open Access
2 Citations
2,451 Views
10 Pages

31 May 2023

The bioactive compounds of coffee are involved in lipid metabolism, and sex differences may play an important role. This study aimed to evaluate the influence of sex differences on serum lipid profiles among habitual coffee drinkers. We conducted a n...

  • Article
  • Open Access
8 Citations
4,321 Views
12 Pages

13 June 2023

The adrenal steroid hormones, cortisol and dehydroepiandrosterone sulfate (DHEAS), are associated with the immune system in opposite actions. This study aimed to investigate the relationship between cortisol and DHEAS serum concentrations, their rati...

  • Article
  • Open Access
6 Citations
2,511 Views
12 Pages

Association between Cholesterol Level and the Risk of Hematologic Malignancy According to Menopausal Status: A Korean Nationwide Cohort Study

  • Wonyoung Jung,
  • Keun Hye Jeon,
  • Jihun Kang,
  • Taewoong Choi,
  • Kyungdo Han,
  • Sang-Man Jin,
  • Su-Min Jeong and
  • Dong Wook Shin

Recent studies have revealed the possible association between serum cholesterol levels and hematologic malignancy (HM). However, limited information is available about how reproductive factors interact with this association. Therefore, we investigate...

  • Article
  • Open Access
2 Citations
2,077 Views
13 Pages

A Longitudinal Retrospective Observational Study on Obesity Indicators and the Risk of Impaired Fasting Glucose in Pre- and Postmenopausal Women

  • Myung Ji Nam,
  • Hyunjin Kim,
  • Yeon Joo Choi,
  • Kyung-Hwan Cho,
  • Seon Mee Kim,
  • Yong-Kyun Roh,
  • Kyungdo Han,
  • Jin-Hyung Jung,
  • Yong-Gyu Park and
  • Do-Hoon Kim

16 May 2022

The impact of obesity could differ according to menopausal status since women undergo significant physiologic and metabolic changes due to menopause. We investigated the association between various major obesity indicators and the risk of impaired fa...

  • Article
  • Open Access
12 Citations
4,493 Views
12 Pages

Proliferation in Postmenopausal Endometrial Polyps—A Potential for Malignant Transformation

  • Lina Adomaitienė,
  • Rūta Nadišauskienė,
  • Mahshid Nickkho-Amiry,
  • Arvydas Čižauskas,
  • Jolita Palubinskienė,
  • Cathrine Holland and
  • Mourad W Seif

28 August 2019

Background and objectives: Endometrial polyps in asymptomatic postmenopausal women are often incidentally found, yet only 1.51% of them are malignant. Their potential for malignant transformation has not been adequately addressed. The aim of this stu...

  • Article
  • Open Access
1 Citations
761 Views
13 Pages

Comparative Analysis of Differentially Expressed Long Non-Coding RNA in Pre- and Postmenopausal Fibroids

  • Tsai-Der Chuang,
  • Shawn Rysling,
  • Nhu Ton,
  • Daniel Baghdasarian and
  • Omid Khorram

Uterine fibroids (leiomyomas) are benign tumors whose growth is influenced by estrogen and progesterone. This study aimed to compare the profiles of differentially expressed long non-coding RNAs (lncRNAs) in fibroids from postmenopausal and premenopa...

  • Review
  • Open Access
2 Citations
4,354 Views
16 Pages

Current Endocrine Therapy in Hormone-Receptor-Positive Breast Cancer: From Tumor Biology to the Rationale for Therapeutic Tunning

  • Oana Maria Burciu,
  • Adrian-Grigore Merce,
  • Simona Cerbu,
  • Aida Iancu,
  • Tudor-Alexandru Popoiu,
  • Ionut Marcel Cobec,
  • Ioan Sas and
  • Gabriel Mihail Dimofte

16 July 2025

Background and Objectives: The objective of this review is to evaluate the current evidence regarding hormone treatments for both premenopausal and postmenopausal women with early-stage hormone receptor (HR) positive breast cancer. Materials and Meth...

  • Article
  • Open Access
17 Citations
5,805 Views
12 Pages

22 April 2021

The association between soy food and soy isoflavone intake and cardiovascular disease (CVD) risk is uncertain, especially in women. We aimed to investigate this association in Korean women. We analyzed data from the Korean Genome and Epidemiology Stu...

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