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626 Results Found

  • Article
  • Open Access
1 Citations
1,136 Views
19 Pages

26 July 2025

Phase-sensitive surface plasmon resonance (SPR) detection is widely employed in molecular dynamics studies and SPR imaging owing to its real-time capability, high sensitivity, and compatibility with imaging systems. A key research objective is to ach...

  • Article
  • Open Access
2 Citations
4,670 Views
16 Pages

2 August 2018

This paper aims to improve the source tracking efficiency of distributed vibration signals generated by phase-sensitive optical time-domain reflectometry (Φ-OTDR). Considering the two dimensions (time and length) of Φ-OTDR signals, the author...

  • Article
  • Open Access
8 Citations
3,268 Views
17 Pages

Use of Synchrotron Phase-Sensitive Imaging for the Investigation of Magnetopriming and Solar UV-Exclusion Impact on Soybean (Glycine max) Leaves

  • Anis Fatima,
  • Sunita Kataria,
  • Ashish Kumar Agrawal,
  • Balwant Singh,
  • Yogesh Kashyap,
  • Meeta Jain,
  • Marian Brestic,
  • Suleyman I. Allakhverdiev and
  • Anshu Rastogi

8 July 2021

The combined response of exclusion of solar ultraviolet radiation (UV-A+B and UV-B) and static magnetic field (SMF) pre-treatment of 200 mT for 1 h were studied on soybean (Glycine max) leaves using synchrotron imaging. The seeds of soybean with and...

  • Article
  • Open Access
1,594 Views
13 Pages

17 October 2024

Fluorescence lifetime imaging microscopy is sensitive to molecular interactions and environments. In homo-dyne frequency-domain fluorescence lifetime imaging microscopy, images of fluorescence objects are acquired at different phase settings of the d...

  • Article
  • Open Access
24 Citations
3,419 Views
21 Pages

Real-Time Strain and Elasticity Imaging in Phase-Sensitive Optical Coherence Elastography Using a Computationally Efficient Realization of the Vector Method

  • Vladimir Y. Zaitsev,
  • Sergey Y. Ksenofontov,
  • Alexander A. Sovetsky,
  • Alexander L. Matveyev,
  • Lev A. Matveev,
  • Alexey A. Zykov and
  • Grigory V. Gelikonov

24 November 2021

We present a real-time realization of OCT-based elastographic mapping local strains and distribution of the Young’s modulus in biological tissues, which is in high demand for biomedical usage. The described variant exploits the principle of Com...

  • Article
  • Open Access
5 Citations
2,456 Views
19 Pages

Quantitative Phase Imaging as Sensitive Screening Method for Nanoparticle-Induced Cytotoxicity Assessment

  • Anne Marzi,
  • Kai Moritz Eder,
  • Álvaro Barroso,
  • Björn Kemper and
  • Jürgen Schnekenburger

17 April 2024

The assessment of nanoparticle cytotoxicity is challenging due to the lack of customized and standardized guidelines for nanoparticle testing. Nanoparticles, with their unique properties, can interfere with biochemical test methods, so multiple tests...

  • Feature Paper
  • Article
  • Open Access
16 Citations
3,280 Views
24 Pages

An Alternative Phase-Sensitive THz Imaging Technique for Art Conservation: History and New Developments at the ENEA Center of Frascati

  • Andrea Doria,
  • Gian Piero Gallerano,
  • Emilio Giovenale,
  • Luca Senni,
  • Manuel Greco,
  • Marcello Picollo,
  • Costanza Cucci,
  • Kaori Fukunaga and
  • Anne Cecile More

29 October 2020

In recent years, THz imaging techniques have been used in several fields of application. At the beginning of the century, the low availability of powerful THz sources was one of the limiting factors to the advancement of THz technology. At the ENEA c...

  • Article
  • Open Access
12 Citations
4,756 Views
11 Pages

13 March 2020

Spatial phase modulation in an imaging interferometer is utilized in surface plasmon resonance (SPR) based sensing of liquid analytes. In the interferometer, a collimated light beam from a laser diode irradiating at 637.1 nm is passing through a pola...

  • Article
  • Open Access
9 Citations
3,834 Views
14 Pages

Angle-Sensitive Detector Based on Silicon-On-Insulator Photodiode Stacked with Surface Plasmon Antenna

  • Anitharaj Nagarajan,
  • Shusuke Hara,
  • Hiroaki Satoh,
  • Aruna Priya Panchanathan and
  • Hiroshi Inokawa

28 September 2020

We present a pixel-level angle sensitive detector composed of silicon-on-insulator (SOI) photodiode (PD) stacked with a gold surface plasmon (SP) antenna to affect the direction of the incoming light. The surface plasmons are excited in the grating-t...

  • Article
  • Open Access
1 Citations
1,023 Views
4 Pages

1 June 2017

Gastrointestinal stromal tumor (GIST) frequently metastasizes to the liver, and conventional staging computed tomography (CT) protocols use multiphasic contrast enhancement for detection of hepatic lesions. We evaluated the sensitivity of arterial ph...

  • Review
  • Open Access
4 Citations
3,820 Views
17 Pages

Combining Wave and Particle Effects in the Simulation of X-ray Phase Contrast—A Review

  • Emilie Pietersoone,
  • Jean Michel Létang,
  • Simon Rit,
  • Emmanuel Brun and
  • Max Langer

X-ray phase-contrast imaging (XPCI) is a family of imaging techniques that makes contrast visible due to phase shifts in the sample. Phase-sensitive techniques can potentially be several orders of magnitude more sensitive than attenuation-based techn...

  • Article
  • Open Access
5 Citations
2,007 Views
19 Pages

30 June 2024

A qualitative study for a second-order boundary value problem with local or nonlocal diffusion and a cubic nonlinear reaction term, endowed with in-homogeneous Cauchy–Neumann (Robin) boundary conditions, is addressed in the present paper. Provi...

  • Article
  • Open Access
1,173 Views
15 Pages

12 April 2025

In this study, we designed an ultrasound transmit–receive sequence to achieve high-frame-rate vascular wall velocity estimation and high-contrast B-mode imaging. The proposed sequence extends conventional dual-transmission schemes by incorporat...

  • Article
  • Open Access
31 Citations
5,403 Views
8 Pages

14 June 2017

A curvelet denoising method has been proposed to reduce the time domain noise to improve the detection performance in the distributed fiber vibration sensing system based on phase-sensitive optical time domain reflectometry. The raw Rayleigh backscat...

  • Article
  • Open Access
4 Citations
3,007 Views
20 Pages

27 August 2025

This case study examines the integration of artificial intelligence (AI) into undergraduate architectural education through a 2024–25 core studio teaching experiment at Zhejiang University. A dual-module framework was implemented, comprising a...

  • Article
  • Open Access
9 Citations
5,139 Views
17 Pages

A Comparison of Magnetic Resonance Imaging Methods to Assess Multiple Sclerosis Lesions: Implications for Patient Characterization and Clinical Trial Design

  • Ewart Mark Haacke,
  • Evanthia Bernitsas,
  • Karthik Subramanian,
  • David Utriainen,
  • Vinay Kumar Palutla,
  • Kiran Yerramsetty,
  • Prashanth Kumar,
  • Sean K. Sethi,
  • Yongsheng Chen and
  • Yanping Luo
  • + 7 authors

Magnetic resonance imaging (MRI) is a sensitive imaging modality for identifying inflammatory and/or demyelinating lesions, which is critical for a clinical diagnosis of MS and evaluating drug responses. There are many unique means of probing brain t...

  • Article
  • Open Access
15 Citations
3,860 Views
12 Pages

22 February 2021

We propose a weighted singular value decomposition (WSVD) to reduce the random noise in the Rayleigh backscattering signal of the phase-sensitive optical time domain reflectometry (Φ-OTDR) to enhance the detection performance of the distributed vibra...

  • Article
  • Open Access
8 Citations
2,697 Views
12 Pages

Multi-Event Location Denoising Scheme for φ-OTDR Based on FFDNet Network

  • Xiyu Yang,
  • Shuai Li,
  • Yanping Xu,
  • Zhaojun Liu and
  • Zengguang Qin

3 October 2023

In order to improve the signal-to-noise ratio (SNR) of vibration sensing in the phase-sensitive optical time-domain reflectometer (φ-OTDR) system, a fiber sensing signal processing method based on the FFDNet convolutional neural network is propos...

  • Article
  • Open Access
2 Citations
1,452 Views
15 Pages

Fiber Sensing in the 6G Era: Vision Transformers for ϕ-OTDR-Based Road-Traffic Monitoring

  • Robson A. Colares,
  • Leticia Rittner,
  • Evandro Conforti and
  • Darli A. A. Mello

14 March 2025

This article adds to the emergent body of research that examines the potential of 6G as a platform that can combine wired and wireless sensing modalities. We apply vision transformers (ViTs) in a distributed fiber-optic sensing system to evaluate roa...

  • Article
  • Open Access
3 Citations
2,017 Views
17 Pages

Multichannel Classifier for Recognizing Acoustic Impacts Recorded with a phi-OTDR

  • Ivan Alekseevich Barantsov,
  • Alexey Borisovich Pnev,
  • Kirill Igorevich Koshelev,
  • Egor Olegovich Garin,
  • Nickolai Olegovich Pozhar and
  • Roman Igorevich Khan

14 July 2023

The purpose of this work is to increase the security of the perimeter of an area from unauthorized intrusions by creating an improved algorithm for classifying acoustic impacts recorded with a sensor system based on a phase-sensitive optical time ref...

  • Article
  • Open Access
23 Citations
4,348 Views
23 Pages

2 February 2022

Accurate and fast identification of vibration signals detected based on the phase-sensitive optical time-domain reflectometer (Φ-OTDR) is crucial in reducing the false-alarm rate of the long-distance distributed vibration warning system. This stu...

  • Article
  • Open Access
11 Citations
3,538 Views
10 Pages

21 December 2021

Trabecular meshwork (TM) motion abnormality is the leading cause of glaucoma. With technique limitations, how TM moves is still an enigma. This study describes a new laboratory platform to investigate TM motion responses to ocular transients in ex vi...

  • Article
  • Open Access
2 Citations
1,173 Views
15 Pages

A Contrastive Representation Learning Method for Event Classification in Φ-OTDR Systems

  • Tong Zhang,
  • Xinjie Peng,
  • Yifan Liu,
  • Kaiyang Yin and
  • Pengfei Li

1 August 2025

The phase-sensitive optical time-domain reflectometry (Φ-OTDR) system has shown substantial potential in distributed acoustic sensing applications. Accurate event classification is crucial for effective deployment of Φ-OTDR systems, and vario...

  • Communication
  • Open Access
49 Citations
5,268 Views
12 Pages

Real-Time Multi-Class Disturbance Detection for Φ-OTDR Based on YOLO Algorithm

  • Weijie Xu,
  • Feihong Yu,
  • Shuaiqi Liu,
  • Dongrui Xiao,
  • Jie Hu,
  • Fang Zhao,
  • Weihao Lin,
  • Guoqing Wang,
  • Xingliang Shen and
  • Liyang Shao
  • + 4 authors

3 March 2022

This paper proposes a real-time multi-class disturbance detection algorithm based on YOLO for distributed fiber vibration sensing. The algorithm achieves real-time detection of event location and classification on external intrusions sensed by distri...

  • Article
  • Open Access
62 Citations
10,675 Views
18 Pages

Once-Weekly Subcutaneous Semaglutide Improves Fatty Liver Disease in Patients with Type 2 Diabetes: A 52-Week Prospective Real-Life Study

  • Sara Volpe,
  • Giuseppe Lisco,
  • Margherita Fanelli,
  • Davide Racaniello,
  • Valentina Colaianni,
  • Domenico Triggiani,
  • Rossella Donghia,
  • Lucilla Crudele,
  • Roberta Rinaldi and
  • Giuseppina Piazzolla
  • + 3 authors

4 November 2022

Background. Nonalcoholic fatty liver disease (NAFLD) is commonly observed in patients with type 2 diabetes (T2D). Semaglutide, a glucagon-like peptide 1 receptor agonist, may have a therapeutic role by targeting common mechanisms involved in the path...

  • Article
  • Open Access
5 Citations
2,065 Views
14 Pages

Effect of Infarct Location and Size on Left Atrial Function: A Cardiovascular Magnetic Resonance Feature Tracking Study

  • He Zhang,
  • Zhaoxin Tian,
  • Huaibi Huo,
  • Han Li,
  • Hui Liu,
  • Yang Hou,
  • Xu Dai,
  • Ting Liu and
  • Shiqi Jin

24 November 2022

Background: LA function has been recognized as a significant prognostic marker in many cardiovascular diseases. Cardiovascular magnetic resonance feature tracking (CMR-FT) represents a promising technique for left atrial function evaluation. The size...

  • Article
  • Open Access
3 Citations
3,334 Views
9 Pages

High-Sensitivity X-ray Phase Imaging System Based on a Hartmann Wavefront Sensor

  • Ginevra Begani Provinciali,
  • Martin Piponnier,
  • Laura Oudjedi,
  • Xavier Levecq,
  • Fabrice Harms,
  • Alessia Cedola,
  • Ombeline de La Rochefoucauld and
  • Philippe Zeitoun

The Hartman wavefront sensor can be used for X-ray phase imaging with high angular resolution. The Hartmann sensor is able to retrieve both the phase and absorption from a single acquisition. The system calculates the shift in a series of apertures i...

  • Review
  • Open Access
1 Citations
4,801 Views
38 Pages

Research Progress of Grating-Based X-Ray Phase-Contrast Imaging and Key Devices

  • Fangke Zong,
  • Jun Yang,
  • Jinchuan Guo,
  • Jingjin Zhang,
  • Yang Du and
  • Chenggong Zhang

28 February 2025

X-ray phase-contrast imaging presents a significant advancement in the field of X-ray imaging, surpassing traditional X-ray absorption imaging in detecting hydrogen substances. It effectively addresses the limitations of the latter in providing contr...

  • Article
  • Open Access
2 Citations
1,025 Views
11 Pages

5 June 2025

Characterising and quantifying complex multiphase steels is a challenging and time-consuming process, which is often open to subjectivity when based on image analysis of optical metallographic or SEM images. The properties of multiphase steels are hi...

  • Review
  • Open Access
178 Citations
18,382 Views
29 Pages

In-Line Phase-Contrast X-ray Imaging and Tomography for Materials Science

  • Sheridan C. Mayo,
  • Andrew W. Stevenson and
  • Stephen W. Wilkins

24 May 2012

X-ray phase-contrast imaging and tomography make use of the refraction of X-rays by the sample in image formation. This provides considerable additional information in the image compared to conventional X-ray imaging methods, which rely solely on X-r...

  • Article
  • Open Access
11 Citations
4,491 Views
10 Pages

Single-Shot On-Axis Fizeau Polarization Phase-Shifting Digital Holography for Complex-Valued Dynamic Object Imaging

  • Hanzi Liu,
  • Vinu R. V.,
  • Hongliang Ren,
  • Xingpeng Du,
  • Ziyang Chen and
  • Jixiong Pu

23 February 2022

Digital holography assisted with inline phase-shifting methods has the benefit of a large field of view and a high resolution, but it is limited in dynamic imaging due to sequential detection of multiple holograms. Here we propose and experimentally...

  • Article
  • Open Access
20 Citations
4,506 Views
15 Pages

Ultrasonic Imaging of Thick Carbon Fiber Reinforced Polymers through Pulse-Compression-Based Phased Array

  • Muhammad Khalid Rizwan,
  • Stefano Laureti,
  • Hubert Mooshofer,
  • Matthias Goldammer and
  • Marco Ricci

7 February 2021

The use of pulse-compression in ultrasonic non-destructive testing has assured, in various applications, a significant improvement in the signal-to-noise ratio. In this work, the technique is combined with linear phased array to improve the sensitivi...

  • Article
  • Open Access
2 Citations
2,926 Views
11 Pages

Fluorescent Phase-Changing Perfluorocarbon Nanodroplets as Activatable Near-Infrared Probes

  • Catalina-Paula Spatarelu,
  • Austin Van Namen,
  • Sidhartha Jandhyala and
  • Geoffrey P. Luke

The sensitivity of fluorescence imaging is limited by the high optical scattering of tissue. One approach to improve sensitivity to small signals is to use a contrast agent with a signal that can be externally modulated. In this work, we present a ne...

  • Article
  • Open Access
2,019 Views
13 Pages

Low-Photon Counts Coherent Modulation Imaging via Generalized Alternating Projection Algorithm

  • Meng Sun,
  • Tao Liu,
  • George Barbastathis,
  • Yincheng Qi and
  • Fucai Zhang

11 November 2022

Phase contrast imaging is advantageous for mitigating radiation damage to samples, such as biological specimens. For imaging at nanometer or atomic resolution, the required flux on samples increases dramatically and can easily exceed the sample damag...

  • Article
  • Open Access
27 Citations
8,720 Views
15 Pages

Non-Destructive Testing of Archaeological Findings by Grating-Based X-Ray Phase-Contrast and Dark-Field Imaging

  • Veronika Ludwig,
  • Maria Seifert,
  • Tracy Niepold,
  • Georg Pelzer,
  • Jens Rieger,
  • Julia Ziegler,
  • Thilo Michel and
  • Gisela Anton

The analysis of archaeological findings reveals the remaining secrets of human history. However, it is a challenging task to investigate and simultaneously preserve the unique remains. Available non-destructive examination methods are limited and oft...

  • Abstract
  • Open Access
1,090 Views
1 Page

Gas-Phase Chemical Imaging System by Biofluorometry for Human VOCs Measurement

  • Kenta Iitani,
  • Koji Toma,
  • Takahiro Arakawa and
  • Kohji Mitsubayashi

Many gas-phase biosensors have been developed for human volatiles (acetone, methyl mercaptan, trimethylamine, ethanol, isopropanol, etc.) and for residential harmful VOCs (formaldehyde, toluene, nicotine) causing some diseases. A novel gas-imaging sy...

  • Article
  • Open Access
2 Citations
947 Views
6 Pages

We aim to focus on improving the performance of slice parallel imaging while simultaneously correcting for spatial shift artifacts related to off-resonance. In multislice controlled aliasing in parallel imaging results in higher acceleration (CAIPIRI...

  • Article
  • Open Access
15 Citations
4,650 Views
17 Pages

18 December 2019

We propose an angle multiplexing method for optics-based image encryption using a phase-only computer-generated hologram (POCGH) in the tilted Fresnel transform (TFrT) domain. Modified Gerchberg-Saxton algorithms, based on the three types of rotation...

  • Article
  • Open Access
2 Citations
3,328 Views
8 Pages

Demonstration of Neutron Phase Imaging Based on Talbot–Lau Interferometer at Compact Neutron Source RANS

  • Hidekazu Takano,
  • Yanlin Wu,
  • Tetsuo Samoto,
  • Atsushi Taketani,
  • Takaoki Takanashi,
  • Chihiro Iwamoto,
  • Yoshie Otake and
  • Atsushi Momose

Neutron imaging based on a compact Talbot–Lau interferometer was demonstrated using the RIKEN accelerator-driven compact neutron source (RANS). A compact Talbot–Lau interferometer consisting of gadolinium absorption gratings and a silicon...

  • Article
  • Open Access
1 Citations
4,444 Views
6 Pages

A multi-aperture analyser set-up was recently developed for X-ray phase contrast imaging and tomography, simultaneously attaining a high sensitivity and wide dynamic range. We present a single-shot image retrieval algorithm in which differential phas...

  • Article
  • Open Access
811 Views
14 Pages

24 October 2025

With the development of extreme ultraviolet (EUV) lithography technology to higher numerical aperture (NA), it provides higher resolution imaging quality, which may be more sensitive to the phase defect in EUV mask. Therefore, it is necessary to comp...

  • Article
  • Open Access
22 Citations
8,833 Views
14 Pages

Improved Reconstruction Technique for Moiré Imaging Using an X-Ray Phase-Contrast Talbot–Lau Interferometer

  • Maria Seifert,
  • Michael Gallersdörfer,
  • Veronika Ludwig,
  • Max Schuster,
  • Florian Horn,
  • Georg Pelzer,
  • Jens Rieger,
  • Thilo Michel and
  • Gisela Anton

X-ray phase-contrast imaging is a promising method for medical imaging and non-destructive testing. Information about the attenuation, small-angle scattering and phase-shifting properties of an object can be gained simultaneously in three image modal...

  • Article
  • Open Access
15 Citations
3,616 Views
12 Pages

23 January 2024

Quantitative phase imaging by digital holographic microscopy (DHM) is a nondestructive and label-free technique that has been playing an indispensable role in the fields of science, technology, and biomedical imaging. The technique is competent in im...

  • Article
  • Open Access
7 Citations
3,577 Views
9 Pages

24 November 2021

Near-field X-ray speckle tracking has been used in phase-contrast imaging and tomography as an emerging technique, providing higher contrast images than traditional absorption radiography. Most reported methods use sandpaper or membrane filters as sp...

  • Article
  • Open Access
662 Views
17 Pages

Step-Free Coating Technique for Four-Quadrant Wind Imaging Interferometer

  • Tingyu Yan,
  • Luhan Huang,
  • Yanqiang Wang and
  • Chunmin Zhang

1 September 2025

The four-quadrant wind imaging interferometer achieves wind field measurement by acquiring interferograms of the target scene in four distinct phase states while maintaining identical radiation intensity. This unique operational principle endows the...

  • Article
  • Open Access
3 Citations
1,378 Views
16 Pages

Gradient Weakly Sensitive Multi-Source Sensor Image Registration Method

  • Ronghua Li,
  • Mingshuo Zhao,
  • Haopeng Xue,
  • Xinyu Li and
  • Yuan Deng

15 April 2024

Aiming at the nonlinear radiometric differences between multi-source sensor images and coherent spot noise and other factors that lead to alignment difficulties, the registration method of gradient weakly sensitive multi-source sensor images is propo...

  • Article
  • Open Access
2 Citations
3,559 Views
22 Pages

22 July 2021

Surface-wave dispersion and the Z/H ratio are important parameters used to resolve the Earth’s structure, especially for S-wave velocity. Several previous studies have explored using joint inversion of these two datasets. However, all of these studie...

  • Article
  • Open Access
1,173 Views
11 Pages

Picometer-Sensitivity Surface Profile Measurement Using Swept-Source Phase Microscopy

  • Jinyun Yue,
  • Jinze Cui,
  • Zhaobo Zheng,
  • Jianjun Liu,
  • Yu Zhao,
  • Shiwei Cui,
  • Yao Yu,
  • Yi Wang,
  • Yuqian Zhao and
  • Zhenhe Ma
  • + 2 authors

15 October 2024

In recent years, the Swept-Source Phase Microscope (SS-PM) has gained more attention due to its greater robustness to sample motion and lower signal decay with depth. However, the mechanical wavelength tuning of the swept source creates small variati...

  • Review
  • Open Access
10 Citations
4,531 Views
28 Pages

Crystal-Based X-ray Interferometry and Its Application to Phase-Contrast X-ray Imaging, Zeff Imaging, and X-ray Thermography

  • Akio Yoneyama,
  • Daiko Takamatsu,
  • Thet-Thet Lwin,
  • Shigehito Yamada,
  • Tetsuya Takakuwa,
  • Kazuyuki Hyodo,
  • Keiichi Hirano and
  • Satoshi Takeya

26 April 2023

Crystal-based X-ray interferometry (CXI) detects X-ray phase shifts by using the superposition of waves, and its sensitivity is the highest among the other X-ray phase-detecting methods. Therefore, phase-contrast X-ray imaging (PCXI) using CXI has th...

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