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52 Results Found

  • Review
  • Open Access
62 Citations
7,579 Views
31 Pages

18 February 2025

The rapid rise of antibiotic resistance has become a global health crisis, necessitating the development of innovative strategies to combat multidrug-resistant (MDR) pathogens. Nanomaterials have emerged as promising tools in this fight, offering uni...

  • Review
  • Open Access
41 Citations
7,439 Views
18 Pages

19 March 2021

Extensive bone defect repair remains a clinical challenge, since ideal implantable scaffolds require the integration of excellent biocompatibility, sufficient mechanical strength and high biological activity to support bone regeneration. The inorgani...

  • Review
  • Open Access
65 Citations
8,583 Views
41 Pages

Trends in Photothermal Nanostructures for Antimicrobial Applications

  • Violeta Dediu,
  • Jana Ghitman,
  • Gratiela Gradisteanu Pircalabioru,
  • Kiat Hwa Chan,
  • Florina Silvia Iliescu and
  • Ciprian Iliescu

The rapid development of antimicrobial resistance due to broad antibiotic utilisation in the healthcare and food industries and the non-availability of novel antibiotics represents one of the most critical public health issues worldwide. Current adva...

  • Review
  • Open Access
9 Citations
2,281 Views
17 Pages

Biofilm-associated infections pose a significant challenge in healthcare, constituting 80% of bacterial infections and often leading to persistent, chronic conditions. Conventional antibiotics struggle with efficacy against these infections due to th...

  • Review
  • Open Access
357 Views
22 Pages

Innovations in Biofilm Prevention and Eradication in Medical Sector: An Integrative Review

  • Konrad Niedźwiadek,
  • Magdalena Polak-Berecka and
  • Adam Waśko

4 December 2025

Background: Biofilm-associated infections remain a major challenge in modern medicine due to their high resistance to antibiotics and immune defences. Advances in materials science, chemistry, and nanotechnology have led to the development of innovat...

  • Review
  • Open Access
69 Citations
10,408 Views
19 Pages

Materials for Orthopedic Bioimplants: Modulating Degradation and Surface Modification Using Integrated Nanomaterials

  • Harbhajan Ahirwar,
  • Yubin Zhou,
  • Chinmaya Mahapatra,
  • Seeram Ramakrishna,
  • Prasoon Kumar and
  • Himansu Sekhar Nanda

12 March 2020

Significant research and development in the field of biomedical implants has evoked the scope to treat a broad range of orthopedic ailments that include fracture fixation, total bone replacement, joint arthrodesis, dental screws, and others. Importan...

  • Review
  • Open Access
25 Citations
5,182 Views
31 Pages

Recent Progress in ZnO-Based Nanostructures for Photocatalytic Antimicrobial in Water Treatment: A Review

  • Ziming Xin,
  • Qianqian He,
  • Shuangao Wang,
  • Xiaoyu Han,
  • Zhongtian Fu,
  • Xinxin Xu and
  • Xin Zhao

7 August 2022

Advances in nanotechnology have led to the development of antimicrobial technology of nanomaterials. In recent years, photocatalytic antibacterial disinfection methods with ZnO-based nanomaterials have attracted extensive attention in the scientific...

  • Review
  • Open Access
46 Citations
4,496 Views
17 Pages

Photo-stimuli-responsive therapeutic nanomaterials have gained widespread attention as frontline materials for biomedical applications. The photoactivation strategies are classified as single-modality (based on either reactive oxygen species (ROS)-ba...

  • Review
  • Open Access
29 Citations
4,333 Views
26 Pages

An Overview of Stimuli-Responsive Intelligent Antibacterial Nanomaterials

  • Jinqiao Zhang,
  • Wantao Tang,
  • Xinyi Zhang,
  • Zhiyong Song and
  • Ting Tong

Drug-resistant bacteria and infectious diseases associated with biofilms pose a significant global health threat. The integration and advancement of nanotechnology in antibacterial research offer a promising avenue to combat bacterial resistance. Nan...

  • Article
  • Open Access
10 Citations
2,713 Views
14 Pages

31 October 2023

Two-dimensional (2D) nanomaterial-based membranes feature attractive properties for molecular separation and transport, which exhibit huge potential in various chemical processes. However, the low permeability and bio-fouling of the MXene membrane in...

  • Review
  • Open Access
17 Citations
3,547 Views
32 Pages

The increased spread and persistence of bacterial drug-resistant phenotypes remains a public health concern and has contributed significantly to the challenge of combating antibiotic resistance. Nanotechnology is considered an encouraging strategy in...

  • Review
  • Open Access
20 Citations
3,903 Views
22 Pages

26 September 2022

The misuse and mismanagement of antibiotics have made the treatment of bacterial infections a challenge. This challenge is magnified when bacteria form biofilms, which can increase bacterial resistance up to 1000 times. It is desirable to develop ant...

  • Review
  • Open Access
4 Citations
2,190 Views
21 Pages

Employing Copper-Based Nanomaterials to Combat Multi-Drug-Resistant Bacteria

  • Yujie Zhai,
  • Zhuxiao Liang,
  • Xijun Liu and
  • Weiqing Zhang

The rise of multi-drug-resistant (MDR) bacteria poses a severe global threat to public health, necessitating the development of innovative therapeutic strategies to overcome these challenges. Copper-based nanomaterials have emerged as promising agent...

  • Review
  • Open Access
233 Citations
15,210 Views
23 Pages

Nanotechnology as a Promising Approach to Combat Multidrug Resistant Bacteria: A Comprehensive Review and Future Perspectives

  • Helal F. Hetta,
  • Yasmin N. Ramadan,
  • Alhanouf I. Al-Harbi,
  • Esraa A. Ahmed,
  • Basem Battah,
  • Noura H. Abd Ellah,
  • Stefania Zanetti and
  • Matthew Gavino Donadu

The wide spread of antibiotic resistance has been alarming in recent years and poses a serious global hazard to public health as it leads to millions of deaths all over the world. The wide spread of resistance and sharing resistance genes between dif...

  • Review
  • Open Access
38 Citations
5,385 Views
22 Pages

Phytochemical-Based Nanomaterials against Antibiotic-Resistant Bacteria: An Updated Review

  • Rocío Díaz-Puertas,
  • Francisco Javier Álvarez-Martínez,
  • Alberto Falco,
  • Enrique Barrajón-Catalán and
  • Ricardo Mallavia

10 March 2023

Antibiotic-resistant bacteria (ARB) is a growing global health threat, leading to the search for alternative strategies to combat bacterial infections. Phytochemicals, which are naturally occurring compounds found in plants, have shown potential as a...

  • Article
  • Open Access
8 Citations
2,461 Views
13 Pages

3 January 2023

In this study, thymol was covalently connected to mesoporous silica nanomaterial by a post-grafting method to obtain a stable antibacterial system, thus overcoming the volatilization of thymol, prolonging the effective time of antibacterial action, a...

  • Review
  • Open Access
60 Citations
7,556 Views
27 Pages

The Impact of Engineered Silver Nanomaterials on the Immune System

  • Neethu Ninan,
  • Nirmal Goswami and
  • Krasimir Vasilev

Over the last decades there has been a tremendous volume of research efforts focused on engineering silver-based (nano)materials. The interest in silver has been mostly driven by the element capacity to kill pathogenic bacteria. In this context, the...

  • Review
  • Open Access
114 Citations
23,027 Views
22 Pages

Antimicrobial Nanomaterials: A Review

  • Gaye Ezgi Yılmaz,
  • Ilgım Göktürk,
  • Mamajan Ovezova,
  • Fatma Yılmaz,
  • Seçkin Kılıç and
  • Adil Denizli

19 July 2023

Microbial colonization on various surfaces is a serious problem. Biofilms from these microbes pose serious health and economic threats. In addition, the recent global pandemic has also attracted great interest in the latest techniques and technology...

  • Review
  • Open Access
63 Citations
8,617 Views
21 Pages

Infectious diseases caused by bacteria represent a global threat to human health. However, due to the abuse of antibiotics, drug-resistant bacteria have evolved rapidly and led to the failure of antibiotics treatment. Alternative antimicrobial strate...

  • Review
  • Open Access
2 Citations
1,331 Views
49 Pages

Multifunctional Nanomaterial-Integrated Hydrogels for Sustained Drug Delivery: From Synthesis and Characterization to Biomedical Application

  • Magdalena Stevanović,
  • Maja Jović,
  • Nenad Filipović,
  • Sara Lukač,
  • Nina Tomić,
  • Lana Popović Maneski and
  • Zoran Stojanović

5 November 2025

Hydrogels have emerged as versatile platforms for controlled and sustained drug delivery due to their high biocompatibility, tunable mechanical properties, and ability to mimic the natural extracellular matrix. Incorporating functional nanomaterials...

  • Review
  • Open Access
10 Citations
3,979 Views
23 Pages

16 February 2023

Bacterial contamination in water bodies is a severe scourge that affects human health and causes mortality and morbidity. Researchers continue to develop next-generation materials for controlling bacterial infections from water. Photo-antibacterial a...

  • Article
  • Open Access
1 Citations
1,417 Views
9 Pages

One-Pot Synthesis of Carbon Nanodots Retrieved from Motorcycle Exhaust: Antibacterial and Antibiofilm Applications

  • Stinil Sam,
  • Jae-Wook Oh,
  • Prasanth Venkatachalam,
  • Manikandan Muthu and
  • Judy Gopal

30 August 2024

Carbon nanodots (CNDs) are nanoscale carbon-based materials with particle sizes typically less than 10 nm. They are characterized by their unique electronic, optical, and surface properties, as well as their bright and tunable fluorescence across the...

  • Review
  • Open Access
2,519 Views
27 Pages

Antimicrobial Potential of Nanomaterials Synthesized with Extracts from Annona Plants: A Review

  • Yared Gutiérrez-Pinzón,
  • Alma Hortensia Martínez-Preciado,
  • José Miguel Velázquez-López,
  • Cristina Pech-Jiménez,
  • Víctor Manuel Zúñiga-Mayo,
  • Santiago José Guevara-Martínez and
  • Gilberto Velázquez-Juárez

Plants of the Annona genus have garnered increasing scientific interest due to their rich phytochemical profile and broad spectrum of biological activities, which include antimicrobial, antiproliferative, and cytotoxic effects. Among the most studied...

  • Article
  • Open Access
20 Citations
5,358 Views
12 Pages

Total Bio-Based Material for Drug Delivery and Iron Chelation to Fight Cancer through Antimicrobial Activity

  • Vincenzo Patamia,
  • Chiara Zagni,
  • Roberto Fiorenza,
  • Virginia Fuochi,
  • Sandro Dattilo,
  • Paolo Maria Riccobene,
  • Pio Maria Furneri,
  • Giuseppe Floresta and
  • Antonio Rescifina

10 July 2023

Bacterial involvement in cancer’s development, along with their impact on therapeutic interventions, has been increasingly recognized. This has prompted the development of novel strategies to disrupt essential biological processes in microbial...

  • Review
  • Open Access
140 Citations
10,238 Views
24 Pages

Carbon Dots as an Emergent Class of Antimicrobial Agents

  • Mattia Ghirardello,
  • Javier Ramos-Soriano and
  • M. Carmen Galan

22 July 2021

Antimicrobial resistance is a recognized global challenge. Tools for bacterial detection can combat antimicrobial resistance by facilitating evidence-based antibiotic prescribing, thus avoiding their overprescription, which contributes to the spread...

  • Review
  • Open Access
54 Citations
6,602 Views
12 Pages

The Use of Nanomedicine for Targeted Therapy against Bacterial Infections

  • Abdulkader Masri,
  • Ayaz Anwar,
  • Naveed Ahmed Khan and
  • Ruqaiyyah Siddiqui

The emergence of drug resistance combined with limited success in the discovery of newer and effective antimicrobial chemotherapeutics poses a significant challenge to human and animal health. Nanoparticles may be an approach for effective drug devel...

  • Review
  • Open Access
167 Citations
9,979 Views
20 Pages

Current Knowledge on the Oxidative-Stress-Mediated Antimicrobial Properties of Metal-Based Nanoparticles

  • Nour Mammari,
  • Emmanuel Lamouroux,
  • Ariane Boudier and
  • Raphaël E. Duval

The emergence of multidrug-resistant (MDR) bacteria in recent years has been alarming and represents a major public health problem. The development of effective antimicrobial agents remains a key challenge. Nanotechnologies have provided opportunitie...

  • Review
  • Open Access
13 Citations
5,123 Views
54 Pages

An Overview of the Potential of Food-Based Carbon Dots for Biomedical Applications

  • Chen-Yow Wang,
  • Nodali Ndraha,
  • Ren-Siang Wu,
  • Hsin-Yun Liu,
  • Sin-Wei Lin,
  • Kuang-Min Yang and
  • Hung-Yun Lin

21 November 2023

Food-based carbon dots (CDs) hold significant importance across various fields, ranging from biomedical applications to environmental and food industries. These CDs offer unique advantages over traditional carbon nanomaterials, including affordabilit...

  • Review
  • Open Access
12 Citations
5,567 Views
25 Pages

Nano-Biotechnology for Bacteria Identification and Potent Anti-bacterial Properties: A Review of Current State of the Art

  • Shimayali Kaushal,
  • Nitesh Priyadarshi,
  • Priyanka Garg,
  • Nitin Kumar Singhal and
  • Dong-Kwon Lim

10 September 2023

Sepsis is a critical disease caused by the abrupt increase of bacteria in human blood, which subsequently causes a cytokine storm. Early identification of bacteria is critical to treating a patient with proper antibiotics to avoid sepsis. However, co...

  • Review
  • Open Access
25 Citations
5,584 Views
17 Pages

1 December 2021

Owed to current environmental concerns and crude oil price fluctuations, the design of feasible substitutes to petroleum-based polymeric materials is a major challenge. A lot of effort has been focused on transforming natural vegetable oils (VOs), wh...

  • Article
  • Open Access
21 Citations
3,491 Views
15 Pages

Ag-Activated Metal−Organic Framework with Peroxidase-like Activity Synergistic Ag+ Release for Safe Bacterial Eradication and Wound Healing

  • Jie Zhou,
  • Ning Chen,
  • Jing Liao,
  • Gan Tian,
  • Linqiang Mei,
  • Guoping Yang,
  • Qiang Wang and
  • Wenyan Yin

17 November 2022

Silver nanoparticles (Ag NPs), a commonly used antibacterial nanomaterial, exhibit broad-spectrum antibacterial activity to combat drug-resistant bacteria. However, the Ag NPs often causes a low availability and high toxicity to living bodies due to...

  • Article
  • Open Access
803 Views
14 Pages

Star Polymers as a Reducing Agent of Silver Salt and a Carrier for Silver Nanoparticles

  • Katarzyna Szcześniak,
  • Grzegorz Przesławski,
  • Jakub Kotecki,
  • Weronika Andrzejewska,
  • Katarzyna Fiedorowicz,
  • Marta Woźniak-Budych,
  • Maciej Jarzębski,
  • Piotr Gajewski and
  • Agnieszka Marcinkowska

25 June 2025

Star polymers—macromolecules featuring multiple arms radiating from a central core—offer unique potential for biomedical applications due to their tunable architecture, multifunctionality and ability to incorporate stimuli-responsive and...

  • Review
  • Open Access
25 Citations
5,228 Views
19 Pages

Nanoarchitectures in Management of Fungal Diseases: An Overview

  • Vijay Mishra,
  • Manvendra Singh,
  • Yachana Mishra,
  • Nitin Charbe,
  • Pallavi Nayak,
  • Kalvatala Sudhakar,
  • Alaa A. A. Aljabali,
  • Seyed H. Shahcheraghi,
  • Hamid Bakshi and
  • Ángel Serrano-Aroca
  • + 1 author

31 July 2021

Fungal infections, from mild itching to fatal infections, lead to chronic diseases and death. Antifungal agents have incorporated chemical compounds and natural products/phytoconstituents in the management of fungal diseases. In contrast to antibacte...

  • Review
  • Open Access
30 Citations
14,737 Views
42 Pages

A Comprehensive Overview of Antibacterial Agents for Combating Multidrug-Resistant Bacteria: The Current Landscape, Development, Future Opportunities, and Challenges

  • Ina Gajic,
  • Nina Tomic,
  • Bojana Lukovic,
  • Milos Jovicevic,
  • Dusan Kekic,
  • Milos Petrovic,
  • Marko Jankovic,
  • Anika Trudic,
  • Dragana Mitic Culafic and
  • Marina Milenkovic
  • + 1 author

21 February 2025

Background/Objectives: Antimicrobial resistance poses a major public health challenge. The World Health Organization has identified 15 priority pathogens that require prompt development of new antibiotics. This review systematically evaluates the ant...

  • Review
  • Open Access
63 Citations
10,445 Views
26 Pages

Plant Extract-Synthesized Silver Nanoparticles for Application in Dental Therapy

  • Omnia Ahmed,
  • Nicole Remaliah Samantha Sibuyi,
  • Adewale Oluwaseun Fadaka,
  • Madimabe Abram Madiehe,
  • Ernest Maboza,
  • Mervin Meyer and
  • Greta Geerts

Oral diseases are the most common non-communicable diseases in the world, with dental caries and periodontitis causing major health and social problems. These diseases can progress to systematic diseases and cause disfigurement when left untreated. H...

  • Article
  • Open Access
6 Citations
2,702 Views
18 Pages

An Eco-Benign Biomimetic Approach for the Synthesis of Ni/ZnO Nanocomposite: Photocatalytic and Antioxidant Activities

  • Munirah Sulaiman Othman Alhar,
  • Dost Muhammad,
  • Kamran Tahir,
  • Magdi E. A. Zaki,
  • Muniba Urooj,
  • Sadia Nazir,
  • Karma Albalawi,
  • Hamza S. Al-Shehri,
  • Ebraheem Abdu Musad Saleh and
  • Afaq Ullah Khan

10 February 2023

With the increasing demand for wastewater treatment and multidrug resistance among pathogens, it was necessary to develop an efficient catalyst with enhanced photocatalytic and antibacterial applications. The present study proposes a facile and green...

  • Article
  • Open Access
7 Citations
2,494 Views
16 Pages

Synthesis of Tellurium Nanoparticles Using Moringa oleifera Extract, and Their Antibacterial and Antibiofilm Effects against Bacterial Pathogens

  • Bo Ao,
  • Honglin Jiang,
  • Xuan Cai,
  • Decheng Liu,
  • Junming Tu,
  • Xiaoshan Shi,
  • Yanxiang Wang,
  • Fei He,
  • Jing Lv and
  • Jingjing Li
  • + 3 authors

Today, pathogenic microorganisms are increasingly developing resistance to conventional drugs, necessitating the exploration of alternative strategies. In addressing this challenge, nano-based antibacterial agents offer a promising avenue of research...

  • Article
  • Open Access
844 Views
15 Pages

ZIF-93-Based Nanomaterials as pH-Responsive Drug Delivery Systems for Enhanced Antibacterial Efficacy of Kasugamycin in the Management of Pear Fire Blight

  • Chunli Chen,
  • Bin Hao,
  • Jincheng Shen,
  • Shuren Liu,
  • Hongzu Feng,
  • Jianwei Zhang,
  • Chen Liu,
  • Yong Li and
  • Hongqiang Dong

25 June 2025

Kasugamycin (KSM) is easily affected by photolysis, acid–base destruction, and oxidative decomposition in the natural environment, leading to its poor durability and low effective utilization rate, which affects its control effect on plant bact...

  • Review
  • Open Access
1 Citations
1,955 Views
26 Pages

12 September 2025

Healthcare-associated infections (HAIs) represent one of the most persistent challenges in modern healthcare delivery, affecting millions of patients worldwide and imposing substantial clinical and economic burdens on healthcare systems. The emergenc...

  • Review
  • Open Access
3 Citations
1,925 Views
18 Pages

Graphene Oxide: Preparation and Medical Research

  • Xulong Huang,
  • Wengang Zhao,
  • Farid Khalilov and
  • Nuo Xu

17 June 2025

Oxide (GO) has emerged as a highly versatile nanomaterial due to its exceptional physicochemical properties, including large surface area, and strong drug-loading capacity. These characteristics have enabled its broad application in fields such as wo...

  • Article
  • Open Access
33 Citations
4,198 Views
13 Pages

24 December 2020

Silver-based hybrid nanomaterials are receiving increasing attention as potential alternatives for traditional antimicrobial agents. Here, we proposed a simple and eco-friendly strategy to efficiently assemble zinc oxide nanoparticles (ZnO) and silve...

  • Review
  • Open Access
10 Citations
4,252 Views
40 Pages

Microenvironmental Behaviour of Nanotheranostic Systems for Controlled Oxidative Stress and Cancer Treatment

  • Yaser Rehman,
  • Hamzeh Qutaish,
  • Jung Ho Kim,
  • Xu-Feng Huang,
  • Sadia Alvi and
  • Konstantin Konstantinov

18 July 2022

The development of smart, efficient and multifunctional material systems for diseases treatment are imperative to meet current and future health challenges. Nanomaterials with theranostic properties have offered a cost effective and efficient solutio...

  • Article
  • Open Access
573 Views
20 Pages

12 October 2025

The escalating crisis of bacterial antimicrobial resistance poses a severe threat to global health, necessitating novel strategies beyond conventional antibiotics. Photothermal therapy (PTT) has emerged as a promising alternative that leverages heat...

  • Review
  • Open Access
49 Citations
6,827 Views
20 Pages

8 October 2022

Frequent bacterial/fungal infections and occurrence of antibiotic resistance pose increasing threats to the public and thus require the development of new antibacterial/antifungal agents and strategies. Carbon dots (CDs) have been well demonstrated t...

  • Communication
  • Open Access
2 Citations
2,604 Views
9 Pages

14 February 2024

Nanomaterials play a crucial role in various aspects of modern life. Zirconia nanoparticles, extensively employed in medicine for fortifying and stabilizing implants in reconstructive medicine, exhibit unique electrical, thermal, catalytic, sensory,...

  • Review
  • Open Access
4 Citations
5,298 Views
18 Pages

Next-Generation Biomaterials for Vital Pulp Therapy: Exploring Biological Properties and Dentin Regeneration Mechanisms

  • Vidhyashree Rajasekar,
  • Mohamed Mahmoud Abdalla,
  • Mengyu Huang,
  • Prasanna Neelakantan and
  • Cynthia Kar Yung Yiu

The advancement of Vital Pulp Therapy (VPT) in dentistry has shown remarkable progress, with a focus on innovative materials and scaffolds to facilitate reparative dentin formation and tissue regeneration. A comprehensive search strategy was performe...

  • Article
  • Open Access
16 Citations
6,884 Views
13 Pages

30 April 2024

The efficacy, targeting ability, and biocompatibility of plant-based nanoparticles can be exploited in fields such as agriculture and medicine. This study highlights the use of plant-based ginger nanoparticles as an effective and promising strategy a...

  • Review
  • Open Access
9 Citations
1,423 Views
55 Pages

21 April 2025

Nanotubes (NTs) are nanosized tube-like structured materials made from various substances such as carbon, boron, or silicon. Carbon nanomaterials (CNMs), including carbon nanotubes (CNTs), graphene/graphene oxide (G/GO), and fullerenes, have good int...

  • Review
  • Open Access
43 Citations
6,707 Views
19 Pages

A Brief Review on Cerium Oxide (CeO2NPs)-Based Scaffolds: Recent Advances in Wound Healing Applications

  • Ishita Allu,
  • Ajay Kumar Sahi,
  • Pooja Kumari,
  • Karunya Sakhile,
  • Alina Sionkowska and
  • Shravanya Gundu

17 April 2023

The process of wound healing is complex and involves the interaction of multiple cells, each with a distinct role in the inflammatory, proliferative, and remodeling phases. Chronic, nonhealing wounds may result from reduced fibroblast proliferation,...

  • Article
  • Open Access
8 Citations
3,723 Views
14 Pages

10 March 2020

Current metal nanomaterials for developing nanofunctional textiles are mostly based on metal nanoparticles (NPs) that show aqueous instability, a tendency to aggregate, and low chemical affinity to biomass textiles, leading to low nano-metal uptake d...

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