Miniaturized mechanical testing based on small sample testing technology is a powerful technique to characterize the mechanical properties of different materials, and it is being used in different application fields. However, the small size of the sp...
A miniature pneumatic bellows device was designed for in-situ testing inside the scanning electron microscope. The device uses a pneumatic actuator to load the specimen and displacement is directly monitored with a linear variable differential transf...
Integrating three-dimensional printing (3DP) in healthcare has modernized medical diagnostics and therapies by presenting various accurate, efficient, and patient-specific tailored solutions. This review critically examines the integration of 3DP in...
Formaldehyde and volatile organic compounds (VOCs) are major indoor pollutants with multiple origins. Standard methods exist to measure them that require analytical expertise and provide, at best, an average value of their concentrations. There is a...
An accurate and easy-to-use Q3 system for on-chip quantitative real-time Polymerase Chain Reaction (qPCR) is hereby demonstrated, and described in detail. The qPCR reactions take place inside a single-use Lab-on-a-Chip with multiple wells, each with...
Point-of-care testing plays an important role in the detection of skin abnormalities. The detection of skin abnormalities requires sufficient depth and no harm. A flexible microwave biosensor based on spoof surface plasmon polaritons was designed to...
The crack initiation and short crack propagation in a martensitic spring steel were investigated by means of in-situ fatigue testing. Shot peened samples as well as untreated samples were exposed to uniaxial alternating stress to analyze the impact o...
Based on the modern microelectromechanical systems technology, we present a revolutionary miniaturized artificial cochlear sensory epithelium for future implantation tests on guinea pigs. The device was curved to fit the spiral structure of the cochl...
Biosensors are ubiquitous in a variety of disciplines, such as biochemical, electrochemical, agricultural, and biomedical areas. They can integrate various point-of-care applications, such as in the food, healthcare, environmental monitoring, water q...
Antimicrobial resistance (AMR) is a global health threat, progressively emerging as a significant public health issue. Therefore, an antibiotic susceptibility study is a powerful method for combating antimicrobial resistance. Antibiotic susceptibilit...
The increasing demand for miniaturized radio-controlled vehicles inspired the following research. The uses of these unmanned miniaturized/micro vehicles range from aero-modeling to drones for urban control and military applications too. The common ch...
In order to test the performance of laser devices for attacking miniature UAVs, we studied the principle of laser devices on soft killing and hard killing. Then, the flight test conditions of miniature UAVs were constructed, and the laser devices wer...
Lightweight constructions and materials offer the opportunity to reduce CO2 emissions in the transport sector. As components in vehicles are often exposed to higher temperatures above 40% of the melting temperature, there is a risk of creep. The cree...
This paper presents and discusses usefulness and possibility of control of the singular points location of a driving magnetic field under as structure considerations as well as selection of energizing magnet systems for miniature electromagnetic swit...
A novel portable wireless volatile organic compound (VOC) monitoring device with disposable sensors is presented. The device is miniaturized, light, easy-to-use, and cost-effective. Different field tests have been carried out to identify the operatio...
The availability of devices for cancer biomarker detection at early stages of the disease is one of the most critical issues in biomedicine. Towards this goal, to increase the assay sensitivity, device miniaturization strategies empowered by the empl...
Miniaturization of multifunctional instruments is key to evolving less invasive medical procedures. The current work outlines steps towards developing a miniature motor to power a cutting tool of a millimeter-scale robot/device (target outside diamet...
This paper presents the design, simulation, fabrication, assembly, and testing of a miniature thermo-pneumatic optofluidic lens. The device comprises two separate zones for air heating and fluid pressing on a flexible membrane. A buried three-dimensi...
In this paper, the fabrication and testing of an integrated passive device (IPD) structure for X-band FMCW radar based on the fan-out wafer-level packaging (FOWLP) process are discussed. First, a transition line structure is added to the IPD structur...
In this study we present the real-time monitoring of three key brain neurochemical species in conscious rats using implantable amperometric electrodes interfaced to a biotelemetric device. The new system, derived from a previous design, was coupled w...
Miniaturization of devices for analysis of chemical composition is being still developed. In this article we present a portable device with a microplasma excitation source. The microdischarge is ignited inside a ceramic structure between a solid anod...
Food safety issues have recently attracted public concern. The deleterious effects of compromised food safety on health have rendered food safety analysis an approach of paramount importance. While conventional techniques such as high-performance liq...
Future food supply will become increasingly dependent on edible material extracted from insects. The growing popularity of artisanal food products enhanced by insect proteins creates particular needs for establishing effective methods for quality con...
This paper reports on a portable selective chemical sensor for hazardous vapors at trace levels, which combines a two-stage purge and trap vapor pre-concentration system, a Micro-Electro-Mechanical-System (MEMS) based fast gas-chromatographic (FAST-G...
A miniaturized Co-based amorphous wire GMI (Giant magneto-impedance) magnetic sensor was designed and fabricated in this paper. The Co-based amorphous wire was used as the sense element due to its high sensitivity to the magnetic field. A three-dimen...
This paper proposes a dynamic compensation method for laser ranging based on pulse width for the miniaturization and high-precision requirements of the initiation device in precision-guided aircraft. The study aims to improve the measurement accuracy...
It is difficult to generate and maintain the vacuum level in vacuum MEMS (Micro-Electro-Mechanical Systems) devices. Currently, there is still no single method or device capable of generating and maintaining the desired vacuum level in a vacuum devic...
The study is aimed to virtually miniaturize medical implants produced of the biocompatible Ti with improved mechanical performance. The results on the simulation-driven design of medical implants fabricated of nanostructured commercially pure Ti with...
Analytical chemistry is now developing mainly in two areas: automation and the creation of complexes that allow, on the one hand, for simultaneously analyzing a large number of samples without the participation of an operator, and on the other, the d...
To improve the overall mechanization level of rapeseed production in China, especially in some hilly regions where ground machinery cannot enter the fields or can only enter with very low economic benefits, a special aerial seeding system for rapesee...
The Sencell sensor uses glucose-induced changes in an osmotic pressure chamber for continuous glucose measurement. A final device shall have the size of a grain of rice. The size limiting factor is the piezo-resistive pressure transducers inside the...
In this work, a miniaturized, automated, and cost-effective ELISA device is designed and implemented, without the utilization of conventional techniques such as pipetting or microfluidic valve technologies. The device has dimensions of 24 cm ×...
Lab-on-a-chip (LOC) devices have been developed for nucleic acid analysis by integrating complex laboratory functions onto a miniaturized chip, enabling rapid, cost-effective, and highly sensitive on-site testing. This review examines the application...
Immunoadsorption (IA) has proven to be clinically effective in the treatment of steroid-refractory multiple sclerosis (MS) relapses, but its mechanism of action remains unclear. We used miniaturized adsorber devices with a tryptophan-immobilized poly...
Closed-loop optogenetic stimulation devices deliver optical stimulations based on real-time measurement and analysis of neural responses to stimulations. However, the use of large bench-top and tethered devices hinders the naturalistic test environme...
Miniaturization precision positioning platforms are needed for in situ nanomechanical test applications. This paper proposes a compact precision positioning platform integrating strain gauges and the piezoactuator. Effects of geometric parameters of...
On the way toward MEMS miniaturization, the quantification of geometric uncertainties stands as a primary challenge. In this paper, an approach that combines genetic algorithms and proper orthogonal decomposition with kriging surrogate modeling was p...
A miniaturized multi-array system is being developed for immune-signature testing. The presented system includes microfluidic chips functionalized with allergens for IgE detection and a custom-made portable reader for fast (~1 s), quantitative, and s...
Digital hydraulic drives are known for their superior efficiency, power density, and robustness. Such advantages make them an attractive alternative (to electric drives) for actuation of exoskeleton devices. This work presents development of a protot...
This paper introduces a miniaturized personal electronic nose (39 mm × 33 mm), which is managed through an app developed on a smartphone. The electronic nose (e-nose) incorporates four new generation digital gas sensors. These MOx-type sensors...
In recent years, the number of interdisciplinary research works related to the development of miniaturized systems with integrated chemical and biological analyses is increasing. Digital microfluidic biochips (DMFBs) are one kind of miniaturized syst...
The development of wearable devices continues to be a growing trend. The mobile health wearables market is extremely fast-moving, with wearable ECG designs demanding increasingly complex features from manufacturers, such as size reduction, high accur...
Considerable efforts are made to develop Point-of-Care (POC) diagnostic tests. POC devices have the potential to match or surpass conventional systems regarding time, accuracy, and cost, and they are significantly easier to operate by or close to the...
Miniature fuses as an anti-damage subsystem perform the important function of protecting electronic devices and systems against permanent damage that may result in electric shocks, fire risks, etc. Their role becomes particularly important when they...
The enzyme-linked Immunosorbent Assay (ELISA) is the gold standard clinical diagnostic tool for the detection and quantification of protein biomarkers. However, conventional ELISA tests have drawbacks in their requirement of time, expensive equipment...
Portable systems for detecting biomolecules have attracted considerable attention, owing to the demand for point-of-care testing applications. This has led to the development of lab-on-a-chip (LOC) devices. However, most LOCs are developed with a foc...
The current miniaturization trend in the market of inertial microsystems is leading to movable device parts with sizes comparable to the characteristic length-scale of the polycrystalline silicon film morphology. The relevant output of micro electro-...
In this paper, the washability of wearable textronic (textile-electronic) devices has been studied. Two different approaches aiming at designing, producing, and testing robust washable and reliable smart textile systems are presented. The common poin...
Miniaturized quantitative assays offer multiplexing capability in a microfluidic device for high-throughput applications such as antimicrobial resistance (AMR) studies. The detection of these multiple microchannels in a single microfluidic device bec...
Miniaturization and integration of chemical devices into modules that aredimensionally comparable with electronic chips (Lab on Chip) is nowadays developingworldwide. The aim of our work was to suggest and optimize the best conditions forfabrication...
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