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Biosensors 2018, 8(2), 35; https://doi.org/10.3390/bios8020035

Sensors Based on Bio and Biomimetic Receptors in Medical Diagnostic, Environment, and Food Analysis

1
Department of Analytical Chemistry, Institute of Chemical Engineering, Ural Federal University named after the first President of Russia B.N. Yeltsin, 620002 Yekaterinburg, Russia
2
Scientific and Innovation Center for Sensory Technologies, Ural State University of Economics, 620144 Yekaterinburg, Russia
*
Author to whom correspondence should be addressed.
Received: 15 March 2018 / Revised: 29 March 2018 / Accepted: 29 March 2018 / Published: 1 April 2018
(This article belongs to the Special Issue Electrochemical (Bio)sensors for Environmental and Food Analyses)
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Abstract

Analytical chemistry is now developing mainly in two areas: automation and the creation of complexes that allow, on the one hand, for simultaneously analyzing a large number of samples without the participation of an operator, and on the other, the development of portable miniature devices for personalized medicine and the monitoring of a human habitat. The sensor devices, the great majority of which are biosensors and chemical sensors, perform the role of the latter. That last line is considered in the proposed review. Attention is paid to transducers, receptors, techniques of immobilization of the receptor layer on the transducer surface, processes of signal generation and detection, and methods for increasing sensitivity and accuracy. The features of sensors based on synthetic receptors and additional components (aptamers, molecular imprinted polymers, biomimetics) are discussed. Examples of bio- and chemical sensors’ application are given. Miniaturization paths, new power supply means, and wearable and printed sensors are described. Progress in this area opens a revolutionary era in the development of methods of on-site and in-situ monitoring, that is, paving the way from the “test-tube to the smartphone”. View Full-Text
Keywords: biosensor; mimetic receptor; non-enzymatic sensor; aptamer; molecular imprinted polymer; transducer; electrochemical sensors; wearable and written sensors; self-powered sensors biosensor; mimetic receptor; non-enzymatic sensor; aptamer; molecular imprinted polymer; transducer; electrochemical sensors; wearable and written sensors; self-powered sensors
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Kozitsina, A.N.; Svalova, T.S.; Malysheva, N.N.; Okhokhonin, A.V.; Vidrevich, M.B.; Brainina, K.Z. Sensors Based on Bio and Biomimetic Receptors in Medical Diagnostic, Environment, and Food Analysis. Biosensors 2018, 8, 35.

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