Search Results (16,936)

Although Artificial Intelligence (AI) has achieved notable performance, particularly in medicine, the structural opacity leading to the black-box phenomenon inhibits interpretability, thus necessitating a balance (Symmetry) between performance and transparency. Specifically, in the medical domain, effective diagnosis requires that high predictive performance be symmetrically counterbalanced by sufficient trust and explainability for clinical practice. Existing visualization techniques like Grad-CAM can highlight attention regions but provide limited insight into the reasoning process and often focus on irrelevant areas. To address this limitation, we propose a Fuzzy Attention Rule (FAR) model that extends fuzzy inference to MRI (Magnetic Resonance Imaging) image classification. The FAR model applies pixel-level fuzzy membership functions and logical operations (AND, OR, AND + OR, AND × OR) to generate rule-based attention maps, enabling explainable and convolution-free feature extraction. Experiments on Kaggle’s Brain MRI and Alzheimer’s MRI datasets show that FAR achieves comparable accuracy to Resnet50 while using far fewer parameters and significantly outperforming MLP. Quantitative and qualitative analyses confirm that FAR focuses more precisely on lesion regions than Grad-CAM. These results demonstrate that fuzzy logic can enhance both the explainability and reliability of medical AI systems without compromising performance. Full article

In recent years, deep learning-based remote sensing object detection has achieved remarkable progress, yet the detection of tiny objects remains a significant challenge. Tiny objects in remote sensing images typically occupy only a few pixels, resulting in low contrast, poor resolution, and high sensitivity to localization errors. Their diverse scales and appearances, combined with complex backgrounds and severe class imbalance, further complicate the detection tasks. Conventional spatial feature extraction methods often struggle to capture the discriminative characteristics of tiny objects, especially in the presence of noise and occlusion. To address these challenges, we propose a frequency-aware attention-based tiny-object detection network with two plug-and-play modules that leverage frequency-domain information to enhance the targets. Specifically, we introduce a Multi-Scale Frequency Feature Enhancement Module (MSFFEM) to adaptively highlight the contour and texture details of tiny objects while suppressing background noise. Additionally, a Channel Attention-based RoI Enhancement Module (CAREM) is proposed to selectively emphasize high-frequency responses within RoI features, further improving object localization and classification. Furthermore, to mitigate sample imbalance, we employ multi-directional flip sample augmentation and redundancy filtering strategies, which significantly boost detection performance for few-shot categories. Extensive experiments on public object detection datasets, i.e., AI-TOD, VisDrone2019, and DOTA-v1.5, demonstrate that the proposed FANet consistently improves detection performance for tiny objects, outperforming existing methods and providing new insights into the integration of frequency-domain analysis and attention mechanisms for robust tiny-object detection in remote sensing applications. Full article

The multimodal fusion of hyperspectral images (HSI) and LiDAR data for land cover classification encounters difficulties in modeling heterogeneous data characteristics and cross-modal dependencies, leading to the loss of complementary information due to concatenation, the inadequacy of fixed fusion weights to adapt to spatially varying reliability, and the assumptions of linear separability for nonlinearly coupled patterns. We propose QIE-Mamba, integrating selective state-space models with quantum-inspired processing to enhance multimodal representation learning. The framework employs ConvNeXt encoders for hierarchical feature extraction, quantum superposition layers for complex-valued multimodal encoding with learned amplitude–phase relationships, unitary entanglement networks via skew-symmetric matrix parameterization (validated through Cayley transform and matrix exponential methods), quantum-enhanced Mamba blocks with adaptive decoherence, and confidence-weighted measurement for classification. Systematic three-phase sequential validation on Houston2013, Muufl, and Augsburg datasets achieves overall accuracies of 99.62%, 96.31%, and 96.30%. Theoretical validation confirms 35.87% mutual information improvement over classical fusion (6.9966 vs. 5.1493 bits), with ablation studies demonstrating quantum superposition contributes 82% of total performance gains. Phase information accounts for 99.6% of quantum state entropy, while gradient convergence analysis confirms training stability (zero mean/std gradient norms). The optimization framework reduces hyperparameter search complexity by 99.6% while maintaining state-of-the-art performance. These results establish quantum-inspired state-space models as effective architectures for multimodal remote sensing fusion, providing reproducible methodology for hyperspectral–LiDAR classification with linear computational complexity. Full article

Advances in deep learning are impressive in various fields and have achieved performance beyond human capabilities in tasks such as image classification, as demonstrated in competitions such as the ImageNet Large Scale Visual Recognition Challenge. Nonetheless, complex applications like medical imaging continue to present significant challenges; a prime example is the Human Protein Atlas (HPA) dataset, which is computationally challenging and complex due to the high-class imbalance with the presence of rare patterns and the need for multi-label classification. It includes 28 distinct patterns and more than 500 unique label combinations, with protein localization that can appear in different cellular regions such as the nucleus, the cytoplasm, and the nuclear membrane. Moreover, the dataset provides four distinct channels for each sample, adding to its complexity, with green representing the target protein, red indicating microtubules, blue showing the nucleus, and yellow depicting the endoplasmic reticulum. We propose a two-phase transfer learning approach based on feature-block extraction from twelve ImageNet-pretrained CNNs. In the first phase, we address single-label multiclass classification using CNNs as feature extractors combined with SVM classifiers on a subset of the HPA dataset. We demonstrate that the simple concatenation of feature blocks extracted from different CNNs improves performance. Furthermore, we apply a genetic algorithm to select the sub-optimal combination of feature blocks. In the second phase, based on the results of the previous stage, we apply two simple multi-label classification strategies and compare their performance with four classifiers. Our method integrates image-level and cell-level analysis. At the image level, we assess the discriminative contribution of individual and combined channels, showing that the green channel is the strongest individually but benefits from combinations with red and yellow. At the cellular level, we extract features from the nucleus and nuclear-membrane ring, an analysis not previously explored in the HPA literature, which proves effective for recognizing rare patterns. Combining these perspectives enhances the detection of rare classes, achieving an F1 score of 0.8 for “Rods & Rings”, outperforming existing approaches. Accurate identification of rare patterns is essential for biological and clinical applications, underscoring the significance of our contribution. Full article

Background/Objectives: Skin cancer is one of the most common diseases in the world, whose early and accurate detection can have a survival rate more than 90% while the chance of mortality is almost 80% in case of late diagnostics. Methods: A modified EfficientNet-B0 is developed based on mobile inverted bottleneck convolution with squeeze and excitation approach. The 3 × 3 convolutional layer is used to capture low-level visual features while the core features are extracted using a sequence of Mobile Inverted Bottleneck Convolution blocks having both 3 × 3 and 5 × 5 kernels. They not only balance fine-grained extraction with broader contextual representation but also increase the network’s learning capacity while maintaining computational cost. The proposed architecture hyperparameters and extracted feature vectors of standard benchmark datasets (HAM10000, ISIC 2019 and MSLD v2.0) of dermoscopic images are optimized with the quantum-behaved particle swarm optimization algorithm (QBPSO). The merit function is formulated by the training loss given in the form of standard classification cross-entropy with label smoothing, mean fitness value (mf^val), average accuracy (mAcc), mean computational time (mCT) and other standard performance indicators. Results: Comprehensive scenario-based simulations were performed using the proposed framework on a publicly available dataset and found an mAcc of 99.62% and 92.5%, mfval of 2.912 × 10⁻¹⁰ and 1.7921 × 10⁻⁸, mCT of 501.431 s and 752.421 s for HAM10000 and ISIC2019 datasets, respectively. The results are compared with state of the art, pre-trained existing models like EfficentNet-B4, RegNetY-320, ResNetXt-101, EfficentNetV2-M, VGG-16, Deep Lab V3 as well as reported techniques based on Mask RCCN, Deep Belief Net, Ensemble CNN, SCDNet and FixMatch-LS techniques having varying accuracies from 85% to 94.8%. The reliability of the proposed architecture and stability of QBPSO is examined through Monte Carlo simulation of 100 independent runs and their statistical soundings. Conclusions: The proposed framework reduces diagnostic errors and assists dermatologists in clinical decisions for an improved patient outcomes despite the challenges like data imbalance and interpretability. Full article

Detecting small objects in unmanned aerial vehicle (UAV) imagery remains a challenging task due to the limited target scale, cluttered backgrounds, severe occlusion, and motion blur commonly observed in dynamic aerial environments. This study presents STAIR-DETR, a real-time synergistic detection framework derived from RT-DETR, featuring comprehensive enhancements in feature extraction, resolution transformation, and detection head design. A Statistical Feature Attention (SFA) module is incorporated into the neck to replace the original AIFI, enabling token-level statistical modeling that strengthens fine-grained feature representation while effectively suppressing background interference. The backbone is reinforced with a Diverse Semantic Enhancement Block (DSEB), which employs multi-branch pathways and dynamic convolution to enrich semantic expressiveness without sacrificing spatial precision. To mitigate information loss during scale transformation, an Adaptive Scale Transformation Operator (ASTO) is proposed by integrating Context-Guided Downsampling (CGD) and Dynamic Sampling (DySample), achieving context-aware compression and content-adaptive reconstruction across resolutions. In addition, a high-resolution P2 detection head is introduced to leverage shallow-layer features for accurate classification and localization of extremely small targets. Extensive experiments conducted on the VisDrone2019 dataset demonstrate that STAIR-DETR attains 41.7% mAP@50 and 23.4% mAP@50:95, outperforming contemporary state-of-the-art (SOTA) detectors while maintaining real-time inference efficiency. These results confirm the effectiveness and robustness of STAIR-DETR for precise small object detection in complex UAV-based imaging scenarios. Full article

Traffic signs exposed to long-term outdoor conditions frequently exhibit deformation, inclination, or other forms of physical damage, highlighting the need for timely and reliable anomaly assessment to support road safety management. While point-cloud data provide accurate three-dimensional geometric information, their sparse distribution and lack of appearance cues make traffic sign extraction challenging in complex environments. High-resolution sequential video-log images captured from multiple viewpoints offer complementary advantages by providing rich color and texture information. In this study, we propose an integrated traffic sign detection and assessment framework that combines video-log images and mobile-mapping point clouds to enhance both accuracy and robustness. A dedicated YOLO-SIGN network is developed to perform precise detection and multi-view association of traffic signs across sequential images. Guided by these detections, a frustum-based point-cloud extraction strategy with seed-point density growing is introduced to efficiently isolate traffic sign panels and supporting poles. The extracted structures are then used for geometric parameterization and damage assessment, including inclination, deformation, and rotation. Experiments on 35 simulated scenes and nine real-world road scenarios demonstrate that the proposed method can reliably extract and evaluate traffic sign conditions in diverse environments. Furthermore, the YOLO-SIGN network achieves a localization precision of 91.16% and a classification mAP of 84.64%, outperforming YOLOv10s by 1.7% and 8.7%, respectively, while maintaining a reduced number of parameters. These results confirm the effectiveness and practical value of the proposed framework for large-scale traffic sign monitoring. Full article

Deep learning has become a powerful tool for diagnosing pests and plant diseases, although conventional convolutional neural networks (CNNs) generally suffer from limited interpretability and suboptimal focus on important image features. This study examines the integration of attention mechanisms into two prevalent CNN architectures—ResNet50 and MobileNetV2—to improve the interpretability and classification of diseases impacting date palm trees. Four attention modules—Squeeze-and-Excitation (SE), Efficient Channel Attention (ECA), Soft Attention, and the Convolutional Block Attention Module (CBAM)—were systematically integrated into ResNet50 and MobileNetV2 and assessed on the Palm Leaves dataset. Using transfer learning, the models were trained and evaluated through accuracy, F1-score, Grad-CAM visualizations, and quantitative metrics such as entropy and Attention Focus Scores. Analysis was also performed on the model’s complexity, including parameters and FLOPs. To confirm generalization, we tested the improved models on field data that was not part of the dataset used for learning. The experimental results demonstrated that the integration of attention mechanisms substantially improved both predictive accuracy and interpretability across all evaluated architectures. For MobileNetV2, the best performance and the most compact attention maps were obtained with SE and ECA (reaching 91%), while Soft Attention improved accuracy but produced broader, less concentrated activation patterns. For ResNet50, SE achieved the most focused and symptom-specific heatmaps, whereas CBAM reached the highest classification accuracy (up to 90.4%) but generated more spatially diffuse Grad-CAM activations. Overall, these findings demonstrate that attention-enhanced CNNs can provide accurate, interpretable, and robust detection of palm tree diseases and pests under real-world agricultural conditions. Full article

Background: Dental caries is a prevalent global oral health issue. The early detection of enamel caries, the initial stage of decay, is critical to preventive dentistry but is often limited by the subjectivity and variability of conventional diagnostic methods. Objective: This study aims to develop and evaluate two explainable deep learning models for the automated classification of enamel caries from intraoral images. Dataset and Methodology: A publicly available dataset of 2000 intraoral images showing early-stage enamel caries, advanced enamel caries, no-caries was used. The dataset was split into training, validation, and test sets in a 70:15:15 ratio, and data preprocessing and augmentation were applied to the training set to balance the dataset and prevent model overfitting. Two models were developed, ExplainableDentalNet, a custom lightweight CNN, and Interpretable ResNet50-SE, a fine-tuned ResNet50 model with Squeeze-and-Excitation blocks, and both were integrated with Gradient-Weighted Class Activation Mapping (Grad-CAM) for visual interpretability. Results: As evaluated on the test set, ExplainableDentalNet achieved an overall accuracy of 96.66% and a Matthews Correlation Coefficient [MCC] = 0.95, while Interpretable ResNet50-SE achieved 98.30% accuracy (MCC = 0.975). McNemar’s test indicated no significant prediction bias, with p > 0.05, and internal bootstrap and cross-validation analyses indicated stable performance. Conclusions: The proposed explainable models demonstrated high diagnostic accuracy in enamel caries classification on the studied dataset. While the present findings are promising, future clinical applications will require external validation on multi-center datasets. Full article

Conveyor belts are among the most critical components of material transport systems across various industrial sectors, including mining, energy, cement production, metallurgy, and logistics. Their reliability directly affects the continuity and operational costs. Traditional methods for assessing belt condition often require downtime, are labor-intensive, and involve a degree of subjectivity. In recent years, there has been a growing interest in non-destructive and remote diagnostic techniques that enable continuous and automated condition monitoring. This paper provides a comprehensive review of current diagnostic solutions, including machine vision systems, infrared thermography, ultrasonic and acoustic techniques, magnetic inspection methods, vibration sensors, and modern approaches based on radar and hyperspectral imaging. Particular attention is paid to the integration of measurement systems with artificial intelligence algorithms for automated damage detection, classification, and failure prediction. The advantages and limitations of each method are discussed, along with the perspectives for future development, such as digital twin concepts and predictive maintenance. The review aims to present recent trends in non-invasive diagnostics of conveyor belts using remote and non-destructive testing techniques, and to identify research directions that can enhance the reliability and efficiency of industrial transport systems. Full article

Glioblastoma (GBM) is one of the most common and aggressive primary malignant tumors of the central nervous system, accounting for about half of all gliomas in adults. Despite intensive research and advances in molecular biology, genomics, and modern neuroimaging techniques, the prognosis for patients with GBM remains extremely poor. Despite the implementation of multimodal treatment involving surgery, radiotherapy, and chemotherapy with temozolomide, the average survival time of patients is only about 15 months. This is primarily due to the complex biology of this cancer, which involves numerous genetic and epigenetic abnormalities, as well as a highly heterogeneous tumor structure and the presence of glioblastoma stem cells with self renewal capacity. Mutations and abnormalities in genes such as IDH-wt, EGFR, PTEN, TP53, TERT, and CDKN2A/B are crucial in the pathogenesis of GBM. In particular, IDH-wt status (wild-type isocitrate dehydrogenase) is one of the most important identification markers distinguishing GBM from other, more favorable gliomas with IDH mutations. Frequent EGFR amplifications and TERT gene promoter mutations lead to the deregulation of tumor cell proliferation and increased aggressiveness. In turn, the loss of function of suppressor genes such as PTEN or CDKN2A/B promotes uncontrolled cell growth and tumor progression. The immunosuppressive tumor microenvironment also plays an important role, promoting immune escape and weakening the effectiveness of systemic therapies, including immunotherapy. The aim of this review is to summarize the current state of knowledge on the epidemiology, classification, pathogenesis, diagnosis, and treatment of glioblastoma multiforme, as well as to discuss the impact of recent advances in molecular and imaging diagnostics on clinical decision-making. A comprehensive review of recent literature (2018–2025) was conducted, focusing on WHO CNS5 classification updates, novel biomarkers (IDH, TERT, MGMT, EGFR), and modern diagnostic techniques such as liquid biopsy, radiogenomics, and next-generation sequencing (NGS). The results of the review indicate that the introduction of integrated histo-molecular diagnostics in the WHO 2021 classification has significantly increased diagnostic precision, enabling better prognostic and therapeutic stratification of patients. Modern imaging techniques, such as advanced magnetic resonance imaging (MRI), positron emission tomography (PET), and radiomics and radiogenomics tools, allow for more precise assessment of tumor characteristics, prediction of response to therapy, and monitoring of disease progression. Contemporary molecular techniques, including DNA methylation profiling and NGS, enable in-depth genomic and epigenetic analysis, which translates into a more personalized approach to treatment. Despite the use of multimodal therapy, which is based on maximum safe tumor resection followed by radiotherapy and temozolomide chemotherapy, recurrence is almost inevitable. GBM shows a high degree of resistance to treatment, which results from the presence of stem cell subpopulations, dynamic clonal evolution, and the ability to adapt to unfavorable microenvironmental conditions. Promising preclinical and early clinical results show new therapeutic strategies, including immunotherapy (cancer vaccines, checkpoint inhibitors, CAR-T therapies), oncolytic virotherapy, and Tumor Treating Fields (TTF) technology. Although these methods show potential for prolonging survival, their clinical efficacy still needs to be confirmed in large studies. The role of artificial intelligence in the analysis of imaging and molecular data is also increasingly being emphasized, which may contribute to the development of more accurate predictive models and therapeutic decisions. Despite these advancements, GBM remains a major therapeutic challenge due to its high heterogeneity and treatment resistance. The integration of molecular diagnostics, artificial intelligence, and personalized therapeutic strategies that may enhance survival and quality of life for GBM patients. Full article

Mass spectrometry imaging (MSI) visualizes the spatial distribution of biomolecules in tissues, whereas ion mobility–mass spectrometry (IM-MS) separates ions through the collision cross-section (CCS) with an inert gas, providing the structural characteristics of isomers. Recent advances have established an integrated workflow, ion mobility–mass spectrometry imaging (IM-MSI), that couples IM with MSI, uniting molecular discrimination with spatial mapping. This synergy has been widely applied in oncology and neuropsychiatric disorders, offering unprecedented insights into biomarker discovery and disease mechanisms. Here, we summarize the principles and classifications of IM-MSI, review their combined biomedical applications, and discuss data processing workflows and commonly used tools. Full article

The mineral deposits in Namibia’s Erongo region are renowned and frequently associated with complex geological environments, including calcrete-hosted paleochannels and hydrothermal alteration zones. Mineral extraction is hindered by high operational costs, restricted accessibility and stringent environmental regulations. To address these challenges, this study proposes an integrated approach that combines satellite remote sensing and machine learning to map and identify mineralisation-indicative zones. Sentinel 2 Multispectral Instrument (MSI) and Landsat 8 Operational Land Imager (OLI) multispectral data were employed due to their global coverage, spectral fidelity and suitability for geological investigations. Normalized Difference Vegetation Index (NDVI) masking was applied to minimise vegetation interference. Spectral indices—the Clay Index, Carbonate Index, Iron Oxide Index and Ferrous Iron Index—were developed and enhanced using false-colour composites. Principal Component Analysis (PCA) was used to reduce redundancy and extract significant spectral patterns. Supervised classification was performed using Support Vector Machine (SVM), Random Forest (RF) and Maximum Likelihood Classification (MLC), with validation through confusion matrices and metrics such as Overall Accuracy, User’s Accuracy, Producer’s Accuracy and the Kappa coefficient. The results showed that RF achieved the highest accuracy on Landsat 8 and MLC outperformed others on Sentinel 2, while SVM showed balanced performance. Sentinel 2’s higher spatial resolution enabled improved delineation of alteration zones. This approach supports efficient and low-impact mineral prospecting in remote environments. Full article

Background: Naso-orbital-ethmoid (NOE) fractures represent complex midface injuries that challenge aesthetic and functional reconstruction. This study evaluates the efficacy of techniques restoring intercanthal distance following operative repair of NOE fractures. Methods: A retrospective case series was conducted of adults undergoing NOE fracture repair between 2010 and 2022. CPT codes were used to identify patients, with inclusion based on radiographic confirmation of NOE fractures. Demographic data, fracture classification, operative techniques, and pre- and post-operative CT measurements of intercanthal distance were analyzed by fracture type and type of repair. Results: 191 patients were identified, mostly male (80%), with Type I fractures being most common (66%). Intercanthal wiring was used in 14% of cases, most frequently for Type II and III fractures. Of the 100 patients with post-operative comparison imaging, the median intercanthal distance improved from 34 mm to 31 mm. Intercanthal wiring yielded greater median distance correction. All patients achieved restoration of intercanthal distance within normal limits regardless of repair technique. Conclusions: Operative repair of NOE fractures using either plating or intercanthal wiring effectively restores normal intercanthal distance. While intercanthal wiring remains valuable in severe fractures, it may not be universally necessary. Further study is needed to refine the role of these repair techniques. Full article

Background/Objectives: Traditional medical image analysis methods often suffer from locality bias, limiting their ability to model long-range contextual relationships between spatially distributed anatomical structures. To overcome this challenge, this study proposes SPX-GNN (Superpixel Explainable Graph Neural Network). This novel method reformulates image analysis as a structural graph learning problem, capturing both local anomalies and global topological patterns in a holistic manner. Methods: The proposed framework decomposes images into semantically coherent superpixel regions, converting them into graph nodes that preserve topological relationships. Each node is enriched with a comprehensive feature vector encoding complementary diagnostic clues, including colour (CIELAB), texture (LBP and Haralick), shape (Hu moments), and spatial location. A Graph Neural Network is then employed to learn the relational dependencies between these enriched nodes. The method was rigorously evaluated using 5-fold stratified cross-validation on a public dataset comprising 4200 chest X-ray images. Results: SPX-GNN demonstrated exceptional performance in tuberculosis classification, achieving a mean accuracy of 99.82%, an F1-score of 99.45%, and a ROC-AUC of 100.00%. Furthermore, an integrated Explainable Artificial Intelligence module addresses the black box problem by generating semantic importance maps, which illuminate the decision mechanism and enhance clinical reliability. Conclusions: SPX-GNN offers a novel approach that successfully combines high diagnostic accuracy with methodological transparency. By providing a robust and interpretable workflow, this study presents a promising solution for medical imaging tasks where structural information is critical, paving the way for more reliable clinical decision support systems. Full article