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1,298 Results Found

  • Article
  • Open Access
4 Citations
3,624 Views
12 Pages

1 November 2021

We aimed to investigate the relationship between cataract surgery and all-cause and cause-specific mortality in Korean elderly patients with cataract using the Korean National Health Insurance Service-Senior cohort database. Elderly patients (≥60 yea...

  • Review
  • Open Access
9 Citations
4,558 Views
11 Pages

17 October 2019

Cataract is a leading cause of blindness worldwide. Currently, restoration of vision in cataract patients requires surgical removal of the cataract. Due to the large and increasing number of cataract patients, the annual cost of surgical cataract tre...

  • Article
  • Open Access
27 Citations
7,642 Views
12 Pages

The Effect of a Mediterranean Diet on the Incidence of Cataract Surgery

  • Alfredo García-Layana,
  • Gianfranco Ciufo,
  • Estefania Toledo,
  • Miguel A. Martínez-González,
  • Dolores Corella,
  • Montse Fitó,
  • Ramon Estruch,
  • Enrique Gómez-Gracia,
  • Miguel Fiol and
  • Fernando Arós
  • + 10 authors

3 May 2017

Background: Cataract is a leading cause of vision impairment worldwide, and surgery is the only available treatment. The process that initiates lens opacification is dependent on the oxidative stress experienced by the lens components. A healthy over...

  • Article
  • Open Access
1,438 Views
12 Pages

Preoperative Risk Factors for Dry Eye Symptoms After Cataract Surgery: Femtosecond Laser-Assisted Cataract Surgery (FLACS) Versus Standard Cataract Surgery (SCS)

  • Elvia Mastrogiuseppe,
  • Luca Lucchino,
  • Francesca Giovannetti,
  • Mattia D’Andrea,
  • Davide Mastromarino,
  • Alice Bruscolini,
  • Alessandro Lambiase and
  • Marco Marenco

8 October 2025

Background: Despite technological advancements in cataract surgery, including Femtosecond Laser-Assisted Cataract Surgery (FLACS), postoperative dry eye disease (DED) remains a challenge, impacting patients’ quality of life. Identifying preoper...

  • Review
  • Open Access
13 Citations
6,427 Views
29 Pages

14 June 2024

Clouding of the transparent eye lens, or cataract(s), is a leading cause of visual impairment that requires surgical replacement with a synthetic intraocular lens to effectively restore clear vision. Most frequently, cataract is acquired with aging a...

  • Systematic Review
  • Open Access
30 Citations
9,920 Views
17 Pages

Corneal Edema after Cataract Surgery

  • Celeste Briceno-Lopez,
  • Neus Burguera-Giménez,
  • M. Carmen García-Domene,
  • M. Amparo Díez-Ajenjo,
  • Cristina Peris-Martínez and
  • M. José Luque

25 October 2023

This systematic review investigates the prevalence and underlying causes of corneal edema following cataract surgery employing manual phacoemulsification. A comprehensive search encompassing databases such as PubMed, Embase, ProQuest, Cochrane Librar...

  • Article
  • Open Access
28 Citations
9,591 Views
7 Pages

Hypertension is the Prominent Risk Factor in Cataract Patients

  • Ioanna Mylona,
  • Maria Dermenoudi,
  • Nikolaos Ziakas and
  • Ioannis Tsinopoulos

2 August 2019

Background and objectives: The purpose of this study is to determine the impact of the most prominent cardiovascular and metabolic risk factors in patients undergoing cataract surgery. Materials and Methods: The study included 812 consecutive patient...

  • Review
  • Open Access
8 Citations
4,120 Views
16 Pages

29 October 2024

Background: Cataracts are the leading cause of blindness worldwide, and age-related cataracts are the result of environmental insults that largely lead to oxidative stress imposed on a genetic background that determines susceptibility to these stress...

  • Review
  • Open Access
52 Citations
13,164 Views
14 Pages

Refractive Outcomes after Cataract Surgery

  • Ramin Khoramnia,
  • Gerd Auffarth,
  • Grzegorz Łabuz,
  • George Pettit and
  • Rajaraman Suryakumar

A post-operative manifest refractive error as close as possible to target is key when performing cataract surgery with intraocular lens (IOL) implantation, given that residual astigmatism and refractive errors negatively impact patients’ vision...

  • Review
  • Open Access
9 Citations
4,270 Views
25 Pages

The major function of eye lens is to transmit light onto retina and form an image. This relies on the crystallin proteins, which are tightly packed to achieve a high refractive index and transparency. The proteins are protected and maintained in a re...

  • Article
  • Open Access
14 Citations
4,179 Views
15 Pages

19 December 2022

Cataract is a major cause of blindness worldwide. In particular, in low-income countries, the burden of disease as well as its direct and indirect economic cost are a major challenge for the population and economy. In many cases, it would be possible...

  • Article
  • Open Access
2 Citations
2,961 Views
10 Pages

The Effect of Cataract Surgery on the Risk of Dementia: A Nationwide Cohort Study

  • Chaeyeon Lee,
  • Eunhae Shin,
  • Mina Kim,
  • Yoonjong Bae,
  • Tae-Young Chung,
  • Sang Won Seo,
  • Hyemin Jang and
  • Dong Hui Lim

10 October 2023

Background: An advanced age and the female sex are widely recognized risk factors for both cataract and dementia. We investigated the effect of cataract surgery on the incidence of dementia in a Korean population aged ≥ 45 years with a previous di...

  • Review
  • Open Access
2 Citations
5,153 Views
10 Pages

Although the origin of cataract surgery is unknown, the earliest identified mention of cataract surgery comes from Chrysippus in the 3rd century B.C.E. This historical review analyses this first description of cataract surgery from both philosophical...

  • Article
  • Open Access
10 Citations
2,856 Views
12 Pages

Parents are a crucial part in the care of children with pediatric cataract. The aim of this study was to explore and explain sense of coherence, family self-efficacy, perceived social support, fatigue and parent reported experiences (PREM), in order...

  • Case Report
  • Open Access
9 Citations
3,500 Views
7 Pages

Novel Mutation in CRYBB3 Causing Pediatric Cataract and Microphthalmia

  • Olivia A. Zin,
  • Luiza M. Neves,
  • Fabiana L. Motta,
  • Dafne D. G. Horovitz,
  • Leticia Guida,
  • Leonardo H. F. Gomes,
  • Daniela P. Cunha,
  • Ana Paula S. Rodrigues,
  • Andrea A. Zin and
  • Zilton F. M. Vasconcelos
  • + 1 author

13 July 2021

Up to 25% of pediatric cataract cases are inherited, with half of the known mutant genes belonging to the crystallin family. Within these, crystallin beta B3 (CRYBB3) has the smallest number of reported variants. Clinical ophthalmological and genetic...

  • Article
  • Open Access
16 Citations
5,087 Views
9 Pages

Incidence and Characteristics of Cataract Surgery in Poland, during 2010–2015

  • Michał S. Nowak,
  • Iwona Grabska-Liberek,
  • Katarzyna Michalska-Małecka,
  • Andrzej Grzybowski,
  • Milena Kozioł,
  • Wojciech Niemczyk,
  • Barbara Więckowska and
  • Jacek P. Szaflik

Background: To assess the incidence and characteristic of cataract surgery in Poland from 2010 to 2015 and to interpret these findings. Patients and methods: Data from all patients who underwent cataract surgery alone or in combined procedures in Pol...

  • Article
  • Open Access
1,188 Views
9 Pages

18 July 2025

Background: Cataract is the leading cause of severe, non-traumatic vision loss worldwide, leading to multiple adverse outcomes in mental health, including depression, anxiety, and cognitive decline; however, the relationship to psychotic symptoms rem...

  • Review
  • Open Access
6 Citations
5,330 Views
13 Pages

27 February 2024

Astigmatism management is a frequently encountered challenge in the world of modern cataract surgery. This review article investigates the importance of astigmatic correction and seeks to uncover the critical components of preoperative evaluation. Wi...

  • Article
  • Open Access
5 Citations
3,224 Views
8 Pages

2 September 2021

The impact of urbanization on cataract incidence is still inconclusive. This study aimed to examine the association of urbanization and sunlight exposure with cataract incidence using a nationwide population-based database in Taiwan. The researchers...

  • Article
  • Open Access
10 Citations
2,919 Views
14 Pages

Is Cataract in Patients under 60 Years Associated with Oxidative Stress?

  • Hanna Lesiewska,
  • Alina Woźniak,
  • Paweł Reisner,
  • Krzysztof Czosnyka,
  • Joanna Stachura and
  • Grażyna Malukiewicz

Oxidative stress is considered as a possible factor in the genesis of cataract. The study aimed to determine the systemic antioxidant status in cataract patients under 60 years. We studied 28 consecutive cataract patients, mean of 53 years (SD = 9.2)...

  • Article
  • Open Access
18 Citations
5,581 Views
15 Pages

An Assessment of Cataract Severity Based on Antioxidant Status and Ascorbic Acid Levels in Aqueous Humor

  • Yu-Ting Tsao,
  • Wei-Chi Wu,
  • Kuan-Jen Chen,
  • Chun-Fu Liu,
  • Yi-Jen Hsueh,
  • Chao-Min Cheng and
  • Hung-Chi Chen

16 February 2022

Cataract is the leading cause of blindness throughout the world. Currently, the cataract severity evaluation is based on the subjective LOCS III guideline. To ameliorate the evaluation system and develop an objective and quantitative analysis, we inv...

  • Article
  • Open Access
3 Citations
4,420 Views
6 Pages

Non-Toxic Anesthesia for Cataract Surgery

  • Alessandro Meduri,
  • Antonio De Maria,
  • Matteo Forlini,
  • Gabriella De Salvo,
  • Purva Date,
  • Maura Mancini,
  • Giovanni William Oliverio and
  • Pasquale Aragona

1 November 2021

Background: To study the safety and efficacy provided by a minimal and localized anesthesia in cataract surgery. Methods: Randomized controlled trial. A total of 100 patients undergoing cataract surgery were randomly divided into two groups of 50, wh...

  • Article
  • Open Access
4 Citations
2,791 Views
13 Pages

Imaging Cataract-Specific Peptides in Human Lenses

  • Kevin L. Schey,
  • Zhen Wang,
  • Kristie L. Rose and
  • David M. G. Anderson

14 December 2022

Age-related protein truncation is a common process in long-lived proteins such as proteins found in the ocular lens. Major truncation products have been reported for soluble and membrane proteins of the lens, including small peptides that can acceler...

  • Review
  • Open Access
28 Citations
7,451 Views
22 Pages

Oxidative Stress in Cataract Formation: Is There a Treatment Approach on the Horizon?

  • Jingyan Li,
  • Francesco Buonfiglio,
  • Ying Zeng,
  • Norbert Pfeiffer and
  • Adrian Gericke

16 October 2024

Cataracts, a leading cause of blindness worldwide, are closely linked to oxidative stress-induced damage to lens epithelial cells (LECs). Key factors contributing to cataract formation include aging, arterial hypertension, and diabetes mellitus. Give...

  • Article
  • Open Access
11 Citations
2,984 Views
12 Pages

Nanogel-Facilitated In-Situ Delivery of a Cataract Inhibitor

  • Dixa Gautam,
  • Michelle G. Pedler,
  • Devatha P. Nair and
  • Jonathan Mark Petrash

4 August 2021

Cataracts are a leading cause of blindness worldwide. Surgical removal of cataracts is a safe and effective procedure to restore vision. However, a large number of patients later develop vision loss due to regrowth of lens cells and subsequent degrad...

  • Article
  • Open Access
35 Citations
4,571 Views
10 Pages

Incidence and Characteristics of Endophthalmitis after Cataract Surgery in Poland, during 2010–2015

  • Michał S. Nowak,
  • Andrzej Grzybowski,
  • Katarzyna Michalska-Małecka,
  • Jacek P. Szaflik,
  • Milena Kozioł,
  • Wojciech Niemczyk and
  • Iwona Grabska-Liberek

Background: The assessment of the incidence and characteristic of acute and chronic postoperative endophthalmitis (POE) after cataract surgery in Poland during 2010–2015. Patients and methods: All hospitalizations of patients, in the National D...

  • Review
  • Open Access
12 Citations
4,686 Views
10 Pages

8 June 2021

Cataract and age-related macular degeneration (AMD) are two of the most common eye diseases of aging. This review addresses the pre-operative, intra-operative, and post-operative considerations in managing cataract in patients with age-related macula...

  • Review
  • Open Access
98 Citations
28,823 Views
21 Pages

Vitamin C and the Lens: New Insights into Delaying the Onset of Cataract

  • Julie C Lim,
  • Mariana Caballero Arredondo,
  • Andrea J. Braakhuis and
  • Paul J. Donaldson

14 October 2020

Cataracts or clouding of the lens is the leading cause of blindness in the world. Age and diabetes are major risk factors, and with an increasing aging and diabetic population, the burden of cataracts will grow. Cataract surgery is an effective way t...

  • Article
  • Open Access
1 Citations
3,787 Views
17 Pages

Hybrid Deep Learning Model for Cataract Diagnosis Assistance

  • Zonghong Feng,
  • Kai Xu,
  • Liangchang Li and
  • Yong Wang

4 December 2024

With the population aging globally, cataracts have become one of the main causes of vision impairment. Early diagnosis and treatment of cataracts are crucial for preventing blindness. However, the use of deep learning models for assisting in the diag...

  • Article
  • Open Access
10 Citations
3,698 Views
11 Pages

Metabolic Syndrome Is Associated with Cataract in a Large Taiwanese Population Study

  • Jung-Hsiu Chang,
  • I-Hua Chen,
  • Jiun-Hung Geng,
  • Pei-Yu Wu,
  • Jiun-Chi Huang and
  • Szu-Chia Chen

19 April 2022

Cataract is the leading cause of blindness worldwide, and metabolic syndrome (MetS) is a known risk factor. In this study, we investigated the association between the risk of cataract with MetS and its components in a large-scale study. Data were der...

  • Article
  • Open Access
2 Citations
1,596 Views
9 Pages

Predictors of Cataract Surgery Among US Adults: NHANES 2007–2008

  • Chisom N. Iwundu,
  • Teija Kohir and
  • Julia E. Heck

Purpose: Cataract, characterized by the clouding of the lens, is the leading cause of blindness and visual impairment worldwide. While cataract surgery is an effective treatment, it carries substantial costs, potential complications, and limited acce...

  • Article
  • Open Access
20 Citations
5,184 Views
20 Pages

A Potential Role for Fructosamine-3-Kinase in Cataract Treatment

  • Sander De Bruyne,
  • Loes van Schie,
  • Jonas Himpe,
  • Filip De Somer,
  • Inge Everaert,
  • Wim Derave,
  • Caroline Van den Broecke,
  • Manon Huizing,
  • Nezahat Bostan and
  • Joris R. Delanghe
  • + 3 authors

Cataracts are the major cause of blindness worldwide, largely resulting from aging and diabetes mellitus. Advanced glycation end products (AGEs) have been identified as major contributors in cataract formation because they alter lens protein structur...

  • Feature Paper
  • Review
  • Open Access
24 Citations
6,548 Views
41 Pages

26 October 2018

Cataract is an eye disease with clouding of the eye lens leading to disrupted vision, which often develops slowly and causes blurriness of the eyesight. Although the restoration of the vision in people with cataract is conducted through surgery, the...

  • Article
  • Open Access
7 Citations
2,840 Views
8 Pages

Vision-Related Quality of Life following Combined Cataract and Minimally Invasive Glaucoma Surgery or Cataract Surgery Alone in Glaucoma Patients

  • Yuki Yuasa,
  • Kazuyuki Hirooka,
  • Naoki Okada,
  • Hiromitsu Onoe,
  • Yumiko Murakami,
  • Hideaki Okumichi and
  • Yoshiaki Kiuchi

This study examined glaucoma patients after undergoing combined cataract and minimally invasive glaucoma surgery (MIGS), microhook ab interno trabeculotomy and goniotomy with the Kahook Dual Blade (KDB), or cataract surgery alone, and it then evaluat...

  • Article
  • Open Access
1 Citations
3,041 Views
17 Pages

AI-Powered Mobile App for Nuclear Cataract Detection

  • Alicja Anna Ignatowicz,
  • Tomasz Marciniak and
  • Elżbieta Marciniak

25 June 2025

Cataract remains the leading cause of blindness worldwide, and the number of individuals affected by this condition is expected to rise significantly due to global population ageing. Early diagnosis is crucial, as delayed treatment may result in irre...

  • Article
  • Open Access
5 Citations
3,512 Views
9 Pages

The Appointment System Influences Uptake of Cataract Surgical Services in Rwanda

  • Gatera Fiston Kitema,
  • Priya Morjaria,
  • Wanjiku Mathenge and
  • Jacqueline Ramke

The aim of this study was to investigate barriers and enablers associated with the uptake of cataract surgery in Rwanda, where financial protection is almost universally available. This was a hospital-based cross-sectional study where potential parti...

  • Article
  • Open Access
56 Citations
16,479 Views
14 Pages

Association between Lutein and Zeaxanthin Status and the Risk of Cataract: A Meta-Analysis

  • Xiao-Hong Liu,
  • Rong-Bin Yu,
  • Rong Liu,
  • Zhen-Xuan Hao,
  • Cheng-Cheng Han,
  • Zhong-Hai Zhu and
  • Le Ma

22 January 2014

The purpose of this meta-analysis was to evaluate the relationship between blood lutein and zeaxanthin concentration and the risk of age-related cataract (ARC). MEDLINE, EMBASE, ISI and Cochrane Library were searched to identify relevant studies up t...

  • Review
  • Open Access
1,124 Views
28 Pages

Management of Dry Eye Disease Pre- and Post-Cataract Surgery: A Personalized Approach

  • Samantha Spritz,
  • Raul E. Ruiz-Lozano,
  • Zahra Bibak-Bejandi,
  • Nicholas W. Setter,
  • Alejandro Rodriguez-Garcia,
  • Zeenal Dabre,
  • Ali Khodor,
  • Robert Schwartz,
  • Sandeep Jain and
  • Ali R. Djalilian

3 February 2026

Dry eye disease (DED) is a common condition that can be associated with cataract surgery, requiring pre- and postoperative considerations. Pre-existent DED and disruption of the tear film homeostasis due to incisional corneal nerve damage, intra-oper...

  • Article
  • Open Access
1,718 Views
12 Pages

Association Between Melatonin Use and Cataract Risk: A Target Trial Emulation Retrospective Cohort Study

  • Cheng-Hsien Hung,
  • Jing-Yang Huang,
  • Yu-Chien Hung,
  • Min-Yen Hsu and
  • James Cheng-Chung Wei

20 August 2025

Oxidative stress has been shown to play an important role in the development of cataracts. Melatonin is an endogenous hormone that has been proposed to have a protective effect against oxidative stress; however, its association with the risk of catar...

  • Review
  • Open Access
25 Citations
10,077 Views
19 Pages

Towards a Connected Mobile Cataract Screening System: A Future Approach

  • Wan Mimi Diyana Wan Zaki,
  • Haliza Abdul Mutalib,
  • Laily Azyan Ramlan,
  • Aini Hussain and
  • Aouache Mustapha

10 February 2022

Advances in computing and AI technology have promoted the development of connected health systems, indirectly influencing approaches to cataract treatment. In addition, thanks to the development of methods for cataract detection and grading using dif...

  • Article
  • Open Access
1 Citations
1,508 Views
10 Pages

Cataract Prevalence in Patients with Cutaneous Melanoma in Lithuanian Population

  • Lukas Šemeklis,
  • Laura Kapitanovaitė,
  • Grinvydas Butrimas,
  • Kamilija Briedė,
  • Laura Račkauskaitė,
  • Reda Žemaitienė and
  • Skaidra Valiukevičienė

8 November 2024

Background/Objectives: Sun exposure and ultraviolet (UV) radiation significantly affect human health, especially concerning skin and eye conditions. Sun exposure is a risk factor for both cutaneous melanoma (CM) and cataract. To investigate the assoc...

  • Article
  • Open Access
3 Citations
5,364 Views
15 Pages

Quality of Life after Cataract Surgery

  • Klaudia Błachnio,
  • Aleksandra Dusińska,
  • Julia Szymonik,
  • Jan Juzwiszyn,
  • Monika Bestecka and
  • Mariusz Chabowski

2 September 2024

Background: The impact of medical intervention on a patient’s quality of life (QoL) is more and more important. Treatment success is defined not only in terms of the success of the procedure performed but also with regard to its impact on diffe...

  • Article
  • Open Access
155 Views
9 Pages

Antioxidant Capacity in Fuchs’ Dystrophy and Its Relationship with Cataract: A Pilot Study

  • Mónica Hernández-Hernández,
  • Mari Carmen García-Domene,
  • Mariola Penadés and
  • Cristina Peris-Martínez

26 February 2026

Background/Objectives: The aim of this study was to compare the level of total proteins and antioxidant capacity in the corneal endothelium of patients with endothelial decompensation, due or not due to a Fuchs’ endothelial dystrophy (FECD), an...

  • Article
  • Open Access
4 Citations
3,690 Views
7 Pages

Femtosecond Laser-Assisted Cataract Surgery: Analysis of Surgical Phases and Comparison with Standard Phacoemulsification in Uncomplicated Cataracts

  • Antonio Baldascino,
  • Matteo Mario Carlà,
  • Federico Giannuzzi,
  • Francesco Boselli,
  • Tomaso Caporossi,
  • Gloria Gambini,
  • Antonio Villano,
  • Aldo Caporossi and
  • Stanislao Rizzo

7 December 2022

The aim of this work is to compare the time of surgical phases and the cumulative dissipated energy (CDE) of the phacoemulsification phase in femtosecond laser-assisted cataract surgery (FLACS) and in standard surgical procedures of phacoemulsificati...

  • Article
  • Open Access
27 Citations
6,114 Views
11 Pages

The Use of Convolutional Neural Networks and Digital Camera Images in Cataract Detection

  • Chi-Ju Lai,
  • Ping-Feng Pai,
  • Marvin Marvin,
  • Hsiao-Han Hung,
  • Si-Han Wang and
  • Din-Nan Chen

Cataract is one of the major causes of blindness in the world. Its early detection and treatment could greatly reduce the risk of deterioration and blindness. Instruments commonly used to detect cataracts are slit lamps and fundus cameras, which are...

  • Review
  • Open Access
7,063 Views
25 Pages

Pharmacological Strategies for Cataract Management: From Molecular Targets to Clinical Translation

  • Laura de Diego-García,
  • Raquel Rejas-González,
  • Ignacio Cereza Latre and
  • Ana Guzman-Aranguez

Cataracts, characterized by the opacification of the eye lens, remain a leading cause of reversible blindness globally. Age and diabetes are key risk factors, and with the increasing aging and diabetic population, the global burden of cataracts is pr...

  • Article
  • Open Access
10 Citations
6,602 Views
11 Pages

Early and Late Complications after Cataract Surgery in Patients with Uveitis

  • Gentian Bajraktari,
  • Tomislav Jukić,
  • Miro Kalauz,
  • Martin Oroz,
  • Andrea Radolović Bertetić and
  • Nenad Vukojević

23 October 2023

Background and Objectives: Uveitis, a prevalent eye disorder characterized by inflammatory processes, often leads to cataract formation and significant visual impairment. This study aimed to evaluate preoperative conditions and postoperative outcomes...

  • Review
  • Open Access
76 Citations
10,972 Views
13 Pages

Diabetes and Phacoemulsification Cataract Surgery: Difficulties, Risks and Potential Complications

  • Andrzej Grzybowski,
  • Piotr Kanclerz,
  • Valentín Huerva,
  • Francisco J. Ascaso and
  • Raimo Tuuminen

Diabetes mellitus is one of the most prevalent chronic diseases worldwide. Diabetic patients are at risk of developing cataract and present for surgery at an earlier age than non-diabetics. The aim of this study was to review the problems associated...

  • Article
  • Open Access
4 Citations
4,986 Views
11 Pages

Predicting the Incidence of Human Cataract through Retinal Imaging Technology

  • Chi-Ting Horng,
  • Han-Ying Sun,
  • Hsiang-Jui Liu,
  • Jiann-Hwa Lue and
  • Shang-Min Yeh

With the progress of science, technology and medicine, the proportion of elderly people in society has gradually increased over the years. Thus, the medical care and health issues of this population have drawn increasing attention. In particular, amo...

  • Article
  • Open Access
2 Citations
5,453 Views
14 Pages

19 November 2024

This study analyzed the survey data of the ophthalmic examination of the 5th National Health and Nutrition Examination Survey to investigate the relationship between the prevalence of cataracts in Koreans and exposure to sunlight in daily life. From...

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