Search Results (170)

Background: The progression of Alzheimer’s Disease (AD) deeply affects not only the diagnosed person but also their close relatives, who are often called to take on the role of informal caregivers. This transition is frequently unplanned and emotionally complex, yet poorly understood in its deeper processual dimensions. This study aims to explore and theorize the transition experienced by a family member becoming the primary informal caregiver for a person with advanced AD. Methods: A qualitative study based on the Constructivist Grounded Theory according to Charmaz’s approach (2006) was conducted. In-depth interviews were carried out with 10 participants who had become informal caregivers for a loved one with advanced AD. Data were analyzed using initial coding, focused coding, the constant comparative method, and theoretical coding. Results: Ten caregivers (mean age 39 years, range 35–54; nine females) of patients with advanced AD participated in the study. The analysis revealed a complex, emotionally intense caregiving experience marked by sacrifice, feelings of powerlessness, identity loss, and the necessity of sharing caregiving responsibilities. A core category emerged: A Silent and Certain Willingness to Care, representing the caregivers’ deep, often unconscious commitment to prioritize the care of their loved ones above their own needs. Four interconnected phases characterized the caregiving process: (1) The Changing Daily Life—involving significant sacrifices in personal and social life; (2) Feeling Powerless—confronting the inevitable decline without means to alter the course; (3) Losing Oneself—experiencing physical and psychological exhaustion and a sense of identity loss; and (4) Sharing with Others—seeking external support to sustain caregiving. These findings highlight the evolving nature of becoming a caregiver and the enduring dedication that sustains this role despite the challenges. Conclusions: The progression of AD deeply transforms the lives of caregivers, who become co-sufferers and active participants in the disease’s management. The results underscore the urgency of designing integrative care strategies—including psychological, social, and potentially technological support—that can enhance both patient outcomes and caregiver resilience. Grounded in real-world experiences, this study contributes to the broader neurodegeneration discourse by emphasizing caregiving as a critical factor in long-term disease management and therapeutic success. Full article

Corporate environmental claims often neglect the substantial ecological impact of land-use changes. This case study examines the spatial dimension of retail-driven land-use transformation by analyzing supermarket expansion in the Veneto region (northern Italy), with a focus on a large grocery retailer. We evaluated its corporate environmental claims by assessing land consumption patterns from 1983 to 2024 using Geographic Information Systems (GIS). The GIS-based methodology involved geocoding 113 Points of Sale (POS—individual retail outlets), performing photo-interpretation of historical aerial imagery, and classifying land-cover types prior to construction. We applied spatial metrics such as total converted surface area, land-cover class frequency across eight categories (e.g., agricultural, herbaceous, arboreal), and the average linear distance between afforestation sites and POS developed on previously rural land. Our findings reveal that 65.97% of the total land converted for Points of Sale development occurred in rural areas, primarily agricultural and herbaceous lands. These landscapes play a critical role in supporting urban biodiversity and providing essential ecosystem services, which are increasingly threatened by unchecked land conversion. While the corporate sustainability reports and marketing strategies emphasize afforestation efforts under their “We Love Nature” initiative, our spatial analysis uncovers no evidence of actual land-use conversion. Additionally, reforestation activities are located an average of 40.75 km from converted sites, undermining their role as effective compensatory measures. These findings raise concerns about selective disclosure and greenwashing, driving the need for more comprehensive and transparent corporate sustainability reporting. The study argues for stronger policy frameworks to incentivize urban regeneration over greenfield development and calls for the integration of land-use data into corporate sustainability disclosures. By combining geospatial methods with content analysis, the research offers new insights into the intersection of land use, business practices, and environmental sustainability in climate-vulnerable regions. Full article

In this paper, I question what the relationship between psychology and spirit would mean for mental well-being if the ideas of the human being and the notion of spirit are viewed from the perspective of Max Scheler’s philosophical anthropology. Scheler provides a view of the human being and of spirit that differs radically from the generally held views, and his philosophical anthropology provides intellectual nourishment. This approach means that I do not look at spirituality as a religious activity or technique, but rather as a dimension of what constitutes the human being, and I explore how this view of spirituality is related to mental health. This paper is therefore divided into two parts. In the first part, I provide a summary of Scheler’s view of five ideologies of the human being in the history of Western philosophy that he identified, pointing out what he saw as their shortcomings. Next, I examine Scheler’s own philosophical anthropology that views the human being as the meeting place of the interpenetrating movements of spirit and impulsion, and as ens amans—a loving being. After that, I explore Scheler’s notion of spirit and personalism, drawing attention to the crucial role of what he describes as the dimension of spirit in his anthropology. In the second part of this paper, I explore the basic theories of well-being—hedonism, desire theories, and objective list theories—and question what a reading of spirituality as the participation in the movement of love would mean to addressing mental health. I conclude that spirituality should not be viewed as just another source of practices and techniques that could enhance human mental health. Rather, spirituality should be understood as a human being’s execution of the act that constitutes the core of his or her being. Spirituality viewed as the execution of the spiritual act of love—spirituality as loving being. Full article

Police officers work in high-stress environments that demand emotional resilience, interpersonal skills, and effective communication. Occupational stress can negatively impact their motivation, conflict resolution abilities, and professional effectiveness. Loving-Kindness Meditation (LKM), a mindfulness-based intervention focused on cultivating compassion and empathy, has shown promise in enhancing prosocial attitudes and emotional regulation. With the rise of short video platforms, digital interventions like video-guided LKM may offer accessible mental health support for law enforcement. This study examines the effects of short video app-guided LKM on police officers’ mindfulness, public service motivation (PSM), conflict resolution skills (CRSs), and communication skills (CSSs). It aims to determine whether LKM can enhance these psychological and professional competencies. A randomized controlled trial (RCT) was conducted with 110 active-duty police officers from a metropolitan police department in China, with 92 completing the study. Participants were randomly assigned to either the LKM group (n = 46) or the waitlist control group (n = 46). The intervention consisted of a 6-week short video app-guided LKM program with daily 10 min meditation sessions. Pre- and post-intervention assessments were conducted using several validated scales: the Mindfulness Attention Awareness Scale (MAAS), the Public Service Motivation Scale (PSM), the Conflict Resolution Styles Inventory (CRSI), and the Communication Competence Scale (CCS). A 2 (Group: LKM vs. Control) × 2 (Time: Pre vs. Post) mixed-design MANOVA was conducted to analyze the effects. Statistical analyses revealed significant group-by-time interaction effects for PSM (F(4,177) = 21.793, p < 0.001, η² = 0.108), CRS (F(4,177) = 20.920, p < 0.001, η² = 0.104), and CSS (F(4,177) = 49.095, p < 0.001, η² = 0.214), indicating improvements in these areas for LKM participants. However, no significant improvement was observed for mindfulness (F(4,177) = 2.850, p = 0.930, η² = 0.016). Short video app-guided LKM improves public service motivation, conflict resolution skills, and communication skills among police officers but does not significantly enhance mindfulness. These findings suggest that brief, digitally delivered compassion-focused programs can be seamlessly incorporated into routine in-service training to strengthen officers’ prosocial motivation, de-escalation competence, and public-facing communication, thereby fostering more constructive police–community interactions. Full article

This article explores the relationship between Ignatian obedience and evangelization through the complementary perspectives of Hans Urs von Balthasar and recent Jesuit General Congregations. It argues that obedience, traditionally viewed as submission to authority, must be reinterpreted as a joyful and loving response to God’s mission, deeply rooted in the trinitarian life. Drawing from Ignatius of Loyola’s foundational texts and the evolving understanding of mission post-Vatican II, this essay highlights a shift from private, intellectual obedience to a more communal and justice-oriented service. The theological depth provided by von Balthasar’s trinitarian model is presented alongside the practical emphasis on social justice and dialogue found in contemporary Jesuit praxis and Pope Francis’ integral ecology. This paper ultimately proposes a synthesis of contemplative fidelity and active engagement, positioning obedience as a vital force in credible, mission-driven evangelization. Full article

Background/Objectives: Happiness is a main topic of psychological research, and as a catalyst for transformative change, it is capable of inspiring growth and well-being. This study aims to identify and understand the themes that compose visual representations of happiness in adolescents, while using an innovative qualitative methodology centered on visual research. Methods: Applying the ‘draw-and-write’ technique, Portuguese adolescents were asked to ‘Draw happiness’, generating a visual data set of 330 drawings, coined hSquares. Results: By order of prevalence, the thematic analysis identified eight key themes: ‘people’, ‘hobbies’, ‘love’, ‘smile’, ‘sports’, ‘basic needs’, ‘inner harmony’, and ‘human rights and equality’. The findings highlight the significance of social contexts, such as family and peer relationships, as central to adolescents’ happiness, while also emphasizing the importance of self-selected activities. Visual representations associated with basic needs and human rights emerged as novel contributions to the literature. Differences emerged by age, with younger adolescents often depicting single themes, whereas older adolescents integrated multiple themes in their drawings. Conclusions: This study provides a visual complement to the rich textual conversation about happiness and demonstrates the potential of visual methodologies in psychological research. Full article

Background: Cancer and fibrotic diseases represent major global health challenges, underscoring the need for safe, multifunctional natural therapies. Although natural products possess notable anticancer properties, their clinical translation is often hindered by non-selective cytotoxicity toward normal cells. Moreover, their therapeutic potential against chronic conditions such as idiopathic pulmonary fibrosis (IPF) remains insufficiently explored. This study aimed to evaluate the efficacy and safety of a natural hydrosol blend, The Greatest Love of Nature (TGLON), in inhibiting cancer cell proliferation and mitigating IPF. Methods: TGLON, composed of 12 steam-distilled plant hydrosols, was chemically characterized by gas chromatography–mass spectrometry (GC-MS). Its cytotoxicity was assessed using the MTT assay against five human cancer cell lines (A-549, HepG2, MCF-7, MKN-45, and MOLT-4) and normal human lung fibroblasts (MRC-5). In vivo safety and therapeutic efficacy were evaluated in Sprague Dawley rats and a bleomycin-induced IPF mouse model, following protocols approved by the Institutional Animal Care and Use Committee (IACUC). Results: TGLON maintained >90% viability in MRC-5 cells at an 80-fold dilution and significantly inhibited the proliferation of A-549 (41%), HepG2 (84%), MCF-7 (50%), MKN-45 (38%), and MOLT-4 (52%) cells. No signs of toxicity were observed in rats administered TGLON orally at 50% (v/v), 10 mL/kg. In mice, TGLON alleviated bleomycin-induced pulmonary inflammation and fibrosis. Conclusions: TGLON exhibited selective anticancer and anti-fibrotic activities under non-toxic conditions, supporting its potential as a bioactive agent for early-stage disease prevention and non-clinical health maintenance. Full article

Dementia-friendly walking football offers a way of helping people who are less likely to engage with traditional services to participate in physical activity and support their physical, mental and social wellbeing. This addresses a gap in the current provision of post-diagnostic dementia support in the UK. However, there is a lack of evidence around such models of service provision. Through the evaluation of a newly established dementia-friendly walking football initiative provided by a Premier League charitable foundation, we explored the social, physical and mental benefits of dementia-friendly walking football for older males from underserved communities. Using a qualitative, exploratory approach, we held focus groups with service providers and service users to understand their views and experiences of delivering and attending dementia-friendly walking football sessions. A thematic analysis of the focus groups revealed three main themes relating to the importance of football to cultural and individual identity, namely, ‘for the love of the game’, ‘team players’ and ‘a game changer’. We also highlight how a multi-disciplinary, research-based approach to the evaluation of a service and identification of service improvements can both involve and benefit people living with dementia and their families. Full article

Antigonon leptopus Hook. & Arn., commonly known as the chain of love, is a fast-growing leafy vine characterized by its pink or white heart-shaped flowers and is considered among the most invasive vine species in Guam. In Guam, the vine is considered to be a weed, but worldwide it is utilized in different folk medicine practices, such as for alleviating colds and tending to wounds. As a resource, A. leptopus is underutilized in Guam, prompting the search for possible pharmacological properties. A. leptopus contains a wide range of phytochemicals, including alkaloids, terpenoids, flavonoids, phenols, tannins, saponins, glycosides, and amino acids, which have been found to have many bioactive properties, including antioxidant, antimicrobial, antidiabetic, anti-inflammatory, and anticancer activities. Extraction methods varied according to specific research objectives, but overall, the most common methods involved were maceration, Soxhlet extraction, and hot extraction techniques. The application of green extraction methods, such as the use of supercritical CO₂, is currently lacking for this species. A. leptopus may serve as a promising source of bioactive compounds for the pharmaceutical and nutraceutical industries. Full article

In Ten Little Indians, Sherman Alexie presents nine poignant and emotionally resonant stories about Native Americans’ struggle with alienation and stereotypes. Instead of focusing merely on the ethnic identity of American Indians, Alexie writes about a particular group of people sharing similar circumstances and addresses their common humanity, namely their search for love and respect in urban spaces. Alexie questions the authenticity of Indian identity and asserts that a “mental reservation” exists in the minds of Indian people which significantly influences their perceptions of self and community. Race, as a medium of seeing “the other” permeates U.S. society, especially in the wake of terrorist attacks. However, racial profiling has proven to be an ineffective means of detecting criminals and criminal activities, and has obstructed social relationships, bringing emotions of fear, loneliness and grief to urban Indians. In response to the modernity crisis, Alexie explores the American Indian cosmopolitanism in Ten Little Indians, and envisions a human social community based on reciprocity and mutual respect. His concerns regarding ordinary people’s life experiences and their ways of forming healthy relationships exhibit his considerable hope for “the triumph of the ordinary”. Full article

Background: “Chemsex” involves the intake of a range of drugs (e.g., synthetic cathinones, gamma-hydroxybutyric acid/gamma-butyrolactone (GHB/GBL), ketamine, methamphetamine, “poppers”, type V phosphodiesterase (PDE) inhibitors, MDMA/ecstasy, cocaine, cannabis, and occasionally a few other molecules as well, to enhance and prolong sexual experiences. This paper aims to provide an overview of the clinical pharmacology of the vast range of drugs that are being used for chemsex with a focus on both the medical and psychopathological disturbances that they can produce. Methods: A narrative literature review was conducted using Pubmed, Scopus, and Web of Science databases. A total of 273 papers published up to January 2025 were screened; articles were selected based on relevance to chemsex/sexualized used behaviour and related substances. Both human and preclinical studies were considered. Results: The use of stimulants is likely related to the need to increase as much as possible both sexual arousal and performance but also to increase social interactions. Furthermore, the empathogenic/entactogenic activities of some MDMA-like “love drugs” facilitate the occurrence of “feeling closer/more intimate” emotional sensations, and GHB/GBL may provide the user with a subjective sensation of disinhibition, hence facilitating condomless meetings with a higher number of random partners. Conversely, ketamine may be used to both enjoy its psychotropic dissociative characteristics and facilitate the potentially painful receptive anal intercourse and/or fisting experiences. Most typically, these drugs are consumed in combination, with polydrug exposure possibly facilitating the occurrence of serotonergic syndrome, seizures, drug–drug pharmacokinetics’ interaction, and sympathomimetic overstimulation. Following these polydrug exposures, a range of psychopathological conditions have at times been reported. These issues may lead to misuse of opiates/opioids, gabapentinoids, and/or antipsychotics. Conclusions: Further actions should aim at reducing the stigma that prevents individuals from accessing necessary healthcare and support services. A multidisciplinary approach that combines medical, psychological, and social support remains key to managing the complex challenges posed by chemsex-related drug use. Full article

Background/Objectives: Endurance exercise increases oxygen demand and, when not balanced by antioxidant defenses, consequently, oxidative stress and inflammatory cytokines increase too. In breast cancer survivors (BCS), post-treatment, physical capacity decreases, lowering life quality. Dragon boat (DB) paddling has shown benefits in reducing lymphedema and improving psychological well-being. This study aimed at non-invasively investigating in BCS, by means of saliva and urine samples, the systemic responses to oxy-inflammation, and appetite hormones after a DB endurance race. Methods: 15 BCS and 15 healthy women (5 (CTR) who performed the DB race too) were studied. BCS and CTR were monitored pre- and post-race. Reactive oxygen species (ROS) production, total antioxidant capacity (TAC), lipid peroxidation (8-iso), DNA oxidation (8-OH-dG), nitric oxide metabolites (NOx), inflammation markers (IL-6-10 and TNFα), appetite hormones, electrolytes concentration, psychometric, and physical scales were assessed. Results: At rest, compared to healthy women, BCS showed a significant increase in oxy-inflammation biomarkers. BCS showed a general increase in oxy-inflammation parameters compared to CTR after the DB race. In BCS, there were the following results: ROS: +80%; lipid peroxidation: +103%; DNA oxidation: +44%; interleukins-6: +179%; IL-10: +55%; TNFα: +9%, NOx: +60% increases and unbalanced appetite hormones: leptin (−32%); and ghrelin (+53%). Moreover, the dragon boat offered a holistic approach to recovery, addressing emotional and social needs supporting belonging, love, and esteem needs, reported to be about 56% of the motivations in this activity, while post-race the following increased: a sense of fatigue (+55%); tiredness (48%); a cold sensation (+15%); and +32% pain. Conclusions: This study provided evidence that, in BCS, a DB endurance race produces an important imbalance in the oxy-inflammation state, at the same time being accompanied by a positive impact on subjective mood and general wellness. Future studies should focus on long-term effects. Full article

Experience within the university landscape significantly shapes students’ environmental attitudes and behaviors. Greenery spaces, water bodies, architectural features, recreational spaces, and sustainable landscape design may not only enhance mental health but also foster a love for and responsibility toward the environment. This study proposed structural equation modeling to evaluate the causal relationship between landscape experiences and students’ environmental awareness by examining the roles of landscape preferences and emotional responses. The findings indicated that (1) when students frequently engage with landscape elements in the university, they tend to attach to the landscape, fostering a sense of belonging and appreciation for healthy learning environments; (2) students’ attachment to the landscape develops positive emotions toward their surroundings; (3) when students value and enjoy the healthy landscapes on campus, they are more likely to exhibit environmental awareness through actions like conserving resources, minimizing waste, and engaging in conservation activities. These behaviors arise from an understanding of the significance of landscapes and the direct impact of positive experiences and favorable emotions associated with these spaces. Therefore, universities can leverage landscape design as a crucial tool to promote sustainable awareness and behavior, guiding students to develop a sense of responsibility toward the natural environment. Full article

As a traditional rice wine, sweet fermented rice (SFR) is widely loved because of its unique flavor and high nutritional value. However, the physicochemical properties, microbial community composition, and metabolic pathway changes during the fermentation process of sweet wine have not been evaluated, and these changes can lead to unstable SFR quality. In this study, we used high-throughput sequencing technology to analyze and elucidate the dynamic changes in the microbial community, metabolic pathways, and carbohydrate enzyme functions in traditional SFR fermentation broth. The results revealed that Rhizopus abundance = 160,943.659 and Wickerhamomyces abundance = 241,660.954 were the predominant fungal genera in the fermentation process from the beginning (A0) to the end (A43) of SFR fermentation. The results of the diversity analysis revealed that the structure and composition of the microbial communities first increased but then decreased. Metabolic pathway analysis showed that energy production and conversion, carbohydrate transport, and amino acid transport were the most active metabolic pathways in fermentation. Moreover, the three primary functions of glycosyltransferases (GTs), glycoside hydrolases (GHs), and carbohydrate-binding modules (CBMs) in carbohydrate enzyme analysis were involved in the whole fermentation process. This study only provides some insight into the dynamic changes in the microbial population of SFR single samples prepared under fixed conditions. It provides a reference for optimizing the physicochemical properties of SFR fermentation broth, controlling the microbial community structure, optimizing fermentation conditions, and improving product quality. Full article

Grief is often seen as a personal response to losing a loved one, but it can also arise from the loss of deeply held values and identities linked to social, structural, and religious spheres. Political grief is a unique form of this, stemming from political policies, laws, and social messaging that certain groups perceive as losses. As societies face political decisions and systemic failures, grief can emerge from losing trust in institutions, shared beliefs, and a sense of belonging. An outgrowth of political grief is a strain on relationships due to polarization, heightened by threat-activating events and resulting tensions. Many people turn to religion to counter feelings of vulnerability and incoherence in today’s political climate. While this may relieve anxiety and provide stability, it can also exacerbate some sources of grief. Understanding these dimensions is crucial for addressing political grief’s broader implications, as individuals and communities seek meaning and attempt to rewrite their narratives in adversity. This discussion includes defining grief beyond death-loss and exploring the interplay between social/political structures and culture. It also considers specific threats and responses, including religious alignment, focusing on recent events in the United States. Full article