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31 Results Found

  • Article
  • Open Access
12 Citations
4,892 Views
19 Pages

20 February 2021

The purpose of this study is to evaluate sufficiency economy philosophy (SEP) performance through annual reports and voluntary sustainable development reports and examines the relationship between SEP performance and firm-specific risk of Thai listed...

  • Article
  • Open Access
16 Citations
5,462 Views
17 Pages

Socioeconomic Disadvantage across the Life Course Is Associated with Diet Quality in Young Adulthood

  • Erin L. Faught,
  • Lindsay McLaren,
  • Sharon I. Kirkpatrick,
  • David Hammond,
  • Leia M. Minaker,
  • Kim D. Raine and
  • Dana Lee Olstad

22 January 2019

Socioeconomic position (SEP) is a key determinant of diet quality across the life course. Young adulthood is a unique period of transition where dietary inequities between groups with lower and higher SEP may widen. This study investigated associatio...

  • Article
  • Open Access
16 Citations
4,295 Views
16 Pages

Development and Validation of Deep-Learning-Based Sepsis and Septic Shock Early Prediction System (DeepSEPS) Using Real-World ICU Data

  • Taehwa Kim,
  • Yunwon Tae,
  • Hye Ju Yeo,
  • Jin Ho Jang,
  • Kyungjae Cho,
  • Dongjoon Yoo,
  • Yeha Lee,
  • Sung-Ho Ahn,
  • Younga Kim and
  • Woo Hyun Cho
  • + 1 author

17 November 2023

Background: Successful sepsis treatment depends on early diagnosis. We aimed to develop and validate a system to predict sepsis and septic shock in real time using deep learning. Methods: Clinical data were retrospectively collected from electronic m...

  • Article
  • Open Access
9 Citations
5,540 Views
12 Pages

Biophysical Changes of Leukocyte Activation (and NETosis) in the Cellular Host Response to Sepsis

  • Matt G. Sorrells,
  • Yurim Seo,
  • Melia Magnen,
  • Bliss Broussard,
  • Roya Sheybani,
  • Ajay M. Shah,
  • Hollis R. O’Neal,
  • Henry T. K. Tse,
  • Mark R. Looney and
  • Dino Di Carlo

Sepsis, the leading cause of mortality in hospitals, currently lacks effective early diagnostics. A new cellular host response test, the IntelliSep test, may provide an indicator of the immune dysregulation characterizing sepsis. The objective of thi...

  • Article
  • Open Access
4 Citations
2,820 Views
13 Pages

Mold Fungal Resistance of Loose-Fill Thermal Insulation Materials Based on Processed Wheat Straw, Corn Stalk and Reed

  • Ramunas Tupciauskas,
  • Zigmunds Orlovskis,
  • Karlis Trevors Blums,
  • Janis Liepins,
  • Andris Berzins,
  • Gunars Pavlovics and
  • Martins Andzs

19 February 2024

The present study evaluates the mold fungal resistance of newly developed loose-fill thermal insulation materials made of wheat straw, corn stalk and water reed. Three distinct techniques for the processing of raw materials were used: mechanical crus...

  • Article
  • Open Access
1,242 Views
14 Pages

Sex and Gender Disparities in Missed Acute Ischemic Stroke: A Nested Case-Control Study

  • Cécile Barras,
  • Michael Amiguet,
  • Joëlle Schwarz,
  • Patrik Michel and
  • Carole Clair

Backround: The aim is to analyze whether sex and gender are associated with missed acute ischemic stroke (M-AIS). Methods: We performed a nested case-control study, using data collected from March 2003 to December 2020 from ASTRAL (Acute STroke Regis...

  • Article
  • Open Access
1 Citations
9,137 Views
10 Pages

Assessing the Effects of the Topical Application of L-Menthol on Pain-Related Somatosensory-Evoked Potentials Using Intra-Epidermal Stimulation

  • Taiki Makibuchi,
  • Koya Yamashiro,
  • Sayaka Anazawa,
  • Tomomi Fujimoto,
  • Genta Ochi,
  • Koyuki Ikarashi and
  • Daisuke Sato

L-menthol is known to activate transient receptor potential melastatin 8 (TRPM8) and induce analgesia to thermal stimuli. However, since thermal stimulation leads to the interaction among the other TRP channels, it was unclear whether L-menthol cause...

  • Article
  • Open Access
31 Citations
8,567 Views
16 Pages

Effectiveness of a New Exercise Program after Lower Limb Arterial Blood Flow Surgery in Patients with Peripheral Arterial Disease: A Randomized Clinical Trial

  • Edita Jakubsevičienė,
  • Donatas Vasiliauskas,
  • Linas Velička,
  • Raimondas Kubilius,
  • Eglė Milinavičienė and
  • Jonė Venclovienė

Objective: The aim of this study was to evaluate the effectiveness of a supervised exercise program (SEP) plus at home nonsupervised exercise therapy (non-SET) on functional status, quality of life (QoL) and hemodynamic response in post-lower-limb...

  • Article
  • Open Access
4,798 Views
9 Pages

Comparative Effectiveness of Dalerpen vs. Branded and Other Generic Tadalafil: The “Shift Study”

  • Davide Arcaniolo,
  • Carlos Miacola,
  • Marco Bitelli,
  • Luca Boeri,
  • Tommaso Cai,
  • Carlo Ceruti,
  • Celeste Manfredi,
  • Ilaria Ortensi,
  • Fabrizio Palumbo and
  • Alessandro Palmieri
  • + 3 authors

28 July 2025

Background: Phosphodiesterase type 5 inhibitors (PDE5i), particularly tadalafil and sildenafil, are the first-line therapies for erectile dysfunction (ED). After the patent expiration of branded tadalafil in 2017, generic formulations became availabl...

  • Article
  • Open Access
8 Citations
5,324 Views
15 Pages

Background: Brookings Institution has identified postponing childbirth from teenage to adulthood as a major strategy that is needed for upward social mobility of women. However, according to the Minorities’ Diminished Returns (MDRs), the associ...

  • Article
  • Open Access
1 Citations
1,487 Views
17 Pages

Ready for School: A Multi-Dimensional Approach to School Readiness Assessment in Hispanic Children from Puerto Rico

  • Mary Rodríguez-Rabassa,
  • Kamalich Muniz-Rodriguez,
  • Allison A. Appleton,
  • Marilyn Borges-Rodríguez,
  • Nicole E. Ruiz-Raíces,
  • Francisco J. Reyes-Santiago,
  • Odette Olivieri-Ramos and
  • Luisa I. Alvarado-Domenech

15 July 2025

School readiness during early childhood is crucial for future academic success. Existing guidelines recommend a comprehensive approach. This concurrent validation study developed a School Readiness Index (SRI) with five readiness domains: early learn...

  • Article
  • Open Access
19 Citations
3,597 Views
12 Pages

Cortical Reorganization of Early Somatosensory Processing in Hemiparetic Stroke

  • Jordan N. Williamson,
  • William A. Sikora,
  • Shirley A. James,
  • Nishaal J. Parmar,
  • Louis V. Lepak,
  • Carolyn F. Cheema,
  • Hazem H. Refai,
  • Dee H. Wu,
  • Evgeny V. Sidorov and
  • Yuan Yang
  • + 1 author

31 October 2022

The cortical motor system can be reorganized following a stroke, with increased recruitment of the contralesional hemisphere. However, it is unknown whether a similar hemispheric shift occurs in the somatosensory system to adapt to this motor change,...

  • Article
  • Open Access
4 Citations
2,661 Views
9 Pages

Clinical Utility of Recently Food and Drug Administration-Approved IntelliSep Test (Sepsis Biomarker) for Early Diagnosis of Sepsis: Comparison with Other Biomarkers

  • Nima Sarani,
  • Amitava Dasgupta,
  • Maria Enders,
  • Lauren Rowan,
  • Hanan Elsarraj,
  • Sarah Gralnek,
  • Madison Shay,
  • Lucas R. Lemar,
  • Steven Q. Simpson and
  • X. Long Zheng
  • + 1 author

16 August 2024

Context: IntelliSep by Cytovale has received United States (U.S.) Food and Drug Administration (FDA) approval as a sepsis biomarker test. However, the clinical utility of this new test is not assessed in emergency departments. Objective: We investiga...

  • Article
  • Open Access
2,467 Views
16 Pages

SepFree NMF: A Toolbox for Analyzing the Kinetics of Sequential Spectroscopic Data

  • Renata Sechi,
  • Konstantin Fackeldey,
  • Surahit Chewle and
  • Marcus Weber

24 August 2022

This work addresses the problem of determining the number of components from sequential spectroscopic data analyzed by non-negative matrix factorization without separability assumption (SepFree NMF). These data are stored in a matrix M of dimension &...

  • Article
  • Open Access
8,893 Views
9 Pages

Icarifil® in Association with Daily Use of Tadalafil (5 mg) versus Standard Tadalafil Daily Dose (5 mg) or Alone: Results from a Controlled, Randomized Clinical Trial

  • Tommaso Cai,
  • Fabrizio Palumbo,
  • Carlos Miacola,
  • Carlo Ceruti,
  • Michele Rizzo,
  • Giovanni Liguori,
  • Luca Gallelli and
  • Alessandro Palmieri

26 April 2024

Background: The management of erectile dysfunction (ED) shows several grey zones and new treatments are required to reduce the percentage of patients discontinuing treatment. Here, we aim to evaluate the role of a natural mixture named Icarifil®...

  • Article
  • Open Access
2 Citations
2,601 Views
20 Pages

Surface-Exposed Protein Moieties of Burkholderia cenocepacia J2315 in Microaerophilic and Aerobic Conditions

  • António M. M. Seixas,
  • Carolina Silva,
  • Joana M. M. Marques,
  • Patrícia Mateus,
  • Manuel J. Rodríguez-Ortega,
  • Joana R. Feliciano,
  • Jorge H. Leitão and
  • Sílvia A. Sousa

9 April 2024

Burkholderia cepacia complex infections remain life-threatening to cystic fibrosis patients, and due to the limited eradication efficiency of current treatments, novel antimicrobial therapies are urgently needed. Surface proteins are among the best t...

  • Article
  • Open Access
19 Citations
5,166 Views
23 Pages

15 October 2019

The purpose of this study is to examine the differences in family entrepreneurship background and personal attitudes of students regarding their future career preferences and its effects on the development of specific dimensions of entrepreneurship p...

  • Article
  • Open Access
17 Citations
5,938 Views
12 Pages

Social Demography of Transitional Dietary Patterns in Thailand: Prospective Evidence from the Thai Cohort Study

  • Keren Papier,
  • Susan Jordan,
  • Catherine D’Este,
  • Cathy Banwell,
  • Vasoontara Yiengprugsawan,
  • Sam-ang Seubsman and
  • Adrian Sleigh

27 October 2017

In recent decades, a health-risk transition with changes in diet and lifestyle in low and middle-income countries (LMICs) led to an emergence of chronic diseases. These trends in Southeast Asian LMICs are not well studied. Here, we report on transiti...

  • Article
  • Open Access
4 Citations
2,287 Views
21 Pages

NeuroAiDTM-II (MLC901) Promoted Neurogenesis by Activating the PI3K/AKT/GSK-3β Signaling Pathway in Rat Spinal Cord Injury Models

  • Anam Anjum,
  • Muhammad Dain Yazid,
  • Muhammad Fauzi Daud,
  • Jalilah Idris,
  • Angela Min Hwei Ng,
  • Amaramalar Selvi Naicker,
  • Ohnmar Htwe Rashidah Ismail,
  • Ramesh Kumar Athi Kumar and
  • Yogeswaran Lokanathan

Traumatic damage to the spinal cord (SCI) frequently leads to irreversible neurological deficits, which may be related to apoptotic neurodegeneration in nerve tissue. The MLC901 treatment possesses neuroprotective and neuroregenerative activity. This...

  • Article
  • Open Access
1 Citations
2,053 Views
19 Pages

8 July 2025

This study introduces a deep learning (DL)-based optimal condition monitoring and control system tailored to indoor smart greenhouses, with a novel focus on maintaining symmetry—defined as a dynamic equilibrium among temperature, humidity, and...

  • Article
  • Open Access
8 Citations
3,999 Views
20 Pages

5 September 2019

Alternative lactation housing could reduce aggression when sows are mixed. We aimed to compare the effects of mixing sows in lactation (with or without piglets), at weaning or after insemination, and determine the effects of lactation housing on the...

  • Article
  • Open Access
4 Citations
4,074 Views
9 Pages

Physical activity (PA) is essential for physical, mental, and emotional health; however, few adults engage in enough PA. Group exercise environments such as CrossFit can promote sustained exercise habits through social influence, support, and norms....

  • Article
  • Open Access
15 Citations
4,555 Views
12 Pages

Classical QSAR and Docking Simulation of 4-Pyridone Derivatives for Their Antimalarial Activity

  • Máryury Flores-Sumoza,
  • Jackson J. Alcázar,
  • Edgar Márquez,
  • José R. Mora,
  • Jesús Lezama and
  • Esneyder Puello

1 December 2018

In this work, the minimum energy structures of 22 4-pyridone derivatives have been optimized at Density Functional Theory level, and several quantum molecular, including electronic and thermodynamic descriptors, were computed for these substrates in...

  • Article
  • Open Access
2 Citations
2,592 Views
13 Pages

21 April 2025

The strong correlation between evoked potentials (EPs) and American Spinal Injury Association (ASIA) scores in individuals with spinal cord injury (SCI) suggests that EPs may serve as reliable predictive markers for rehabilitation progress. Numerous...

  • Article
  • Open Access
3,895 Views
12 Pages

Impact of a Sepsis Quality Improvement Initiative on Clinical and Operational Outcomes

  • Christopher B. Thomas,
  • Benjamin Wyler,
  • Claude M. D’Antonio,
  • Mark Laperouse,
  • Shannon Alwood,
  • Kristen Richard,
  • Alyse Grantham,
  • Roya Sheybani,
  • Matt G. Sorrells and
  • Tonya Jagneaux
  • + 3 authors

Background/Objectives: Sepsis is a costly and life-threatening condition caused by a dysregulated host response to infection. Lack of a reliable, timely diagnostic for sepsis leads to under- and overdiagnosis, suboptimal outcomes, and strained hospit...

  • Article
  • Open Access
5 Citations
3,269 Views
21 Pages

8 February 2023

The progression and remission of cervical spondylotic myelopathy (CSM) are quite unpredictable due to the ambiguous pathomechanisms. Spontaneous functional recovery (SFR) has been commonly implicated in the natural course of incomplete acute spinal c...

  • Article
  • Open Access
30 Citations
15,316 Views
9 Pages

Toxicity and Toxin Composition of the Greater Blue-Ringed Octopus Hapalochlaena lunulata from Ishigaki Island, Okinawa Prefecture, Japan

  • Manabu Asakawa,
  • Takuya Matsumoto,
  • Kohei Umezaki,
  • Kyoichiro Kaneko,
  • Ximiao Yu,
  • Gloria Gomez-Delan,
  • Satoshi Tomano,
  • Tamao Noguchi and
  • Susumu Ohtsuka

29 April 2019

The toxicity of the greater blue-ringed octopus Hapalochlaena lunulata, whose bite is fatal to humans, was examined to better understand and prevent deaths from accidental bites. Living specimens were collected from tide pools on Ishigaki Island, Oki...

  • Article
  • Open Access
1 Citations
990 Views
12 Pages

Is GDF15 a Feasible Biomarker in Sepsis?

  • Ertugrul Yigit,
  • Mehmet Akif Simsek,
  • Merve Huner Yigit,
  • Gorkem Akca,
  • Berat Sonmez and
  • Hakki Uzun

2 September 2025

Background/Objectives: Sepsis is a high-mortality syndrome characterized by organ dysfunction resulting from a dysregulated host response to infection. This study aimed to evaluate the potential of growth differentiation factor 15 (GDF15), a stress-i...

  • Article
  • Open Access
1 Citations
5,376 Views
11 Pages

Patient Satisfaction and Outcomes of Penile Prosthesis Implantation in Psychogenic and Organic Erectile Dysfunction: A Comparative Study

  • Maurizio De Rocco Ponce,
  • Alejandro Silva Garretón,
  • Ángela Sousa Iglesias,
  • Sebastian Dumas Castro,
  • Ricardo Contreras Garcia,
  • Luis Malca Caballero,
  • Josvany Rene Sanchez Curbelo,
  • Doron Vantman Luft,
  • Eduard Ruiz Castañé and
  • Osvaldo Rajmil

16 July 2025

Background: Penile prosthesis implantation (PPI) is an established treatment for erectile dysfunction (ED). Nevertheless, the effectiveness of and satisfaction with PPI in mainly psychogenic ED compared to mainly organic ED patients remain underexplo...

  • Article
  • Open Access
12 Citations
6,680 Views
12 Pages

19 November 2022

The Zero-P spacer was primarily developed aiming to reduce the morbidity associated with the traditional anterior cervical plate. During the past decade, many authors have reported the use of Zero-P spacers for anterior cervical discectomy and fusion...

  • Article
  • Open Access
19 Citations
3,526 Views
14 Pages

The comparative molecular similarity index analysis (CoMSIA) model of double-activity quinolones targeting green algae toxicity and bacterial genotoxicity (8:2) was constructed in this paper on the basis of the comprehensive index method. The contour...