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  • Article
  • Open Access
2 Citations
1,253 Views
19 Pages

Single and Combined Effects of Polystyrene Nanoplastics and Dibutyl Phthalate on Hybrid Snakehead (Channa maculata ♀ × Channa argus ♂)

  • Mi Ou,
  • Ziwen Yang,
  • Yuntao Lu,
  • Yang Zhang,
  • Yang Zou,
  • Yueying Deng,
  • Yuandong Sun,
  • Haiyang Liu,
  • Qing Luo and
  • Jian Zhao
  • + 3 authors

3 September 2025

The ecological impact of microplastic pollution in freshwater ecosystems has received growing scientific attention, although research on freshwater species remains limited compared to marine organisms. This study investigates the individual and combi...

  • Article
  • Open Access
1 Citations
431 Views
16 Pages

Polystyrene Nanoparticles Disrupt Oxidative Phosphorylation and Impair Placental Development in Mice

  • Bingyi Wang,
  • Xinyi Xie,
  • Nairui Fan,
  • Qiqi Deng,
  • Nannan Shi,
  • Denglu Long,
  • Weipeng Huang,
  • Siqi Zhu,
  • Zhi Chen and
  • Qihao Zhang
  • + 3 authors

8 February 2026

Background: Microplastics and nanoplastics, as pervasive and persistent environmental pollutants, are raising growing concerns regarding their potential risks to reproductive health, particularly pregnancy outcomes. Although the reproductive toxicity...

  • Article
  • Open Access
42 Citations
4,590 Views
13 Pages

Size-Dependent Effects of Polystyrene Nanoparticles (PS-NPs) on Behaviors and Endogenous Neurochemicals in Zebrafish Larvae

  • Kyu-Seok Hwang,
  • Yuji Son,
  • Seong Soon Kim,
  • Dae-Seop Shin,
  • So Hee Lim,
  • Jung Yoon Yang,
  • Ha Neul Jeong,
  • Byung Hoi Lee and
  • Myung Ae Bae

14 September 2022

Microplastics, small pieces of plastic derived from polystyrene, have recently become an ecological hazard due to their toxicity and widespread occurrence in aquatic ecosystems. In this study, we exposed zebrafish larvae to two types of fluorescent p...

  • Article
  • Open Access
50 Citations
5,118 Views
13 Pages

PS-NPs Induced Neurotoxic Effects in SHSY-5Y Cells via Autophagy Activation and Mitochondrial Dysfunction

  • Qisheng Tang,
  • Tianwen Li,
  • Kezhu Chen,
  • Xiangyang Deng,
  • Quan Zhang,
  • Hailiang Tang,
  • Zhifeng Shi,
  • Tongming Zhu and
  • Jianhong Zhu

Polystyrene nanoparticles (PS-NPs) are organic pollutants that are widely detected in the environment and organisms, posing potential threats to both ecosystems and human health. PS-NPs have been proven to penetrate the blood–brain barrier and...

  • Article
  • Open Access
21 Citations
5,823 Views
18 Pages

Vaccination remains the major approach to the prevention of dengue. Since the only licensed live attenuated vaccine (LAV) lacked efficacy against all four serotypes, other vaccine platforms, such as synthetic peptide vaccines, should be explored. In...

  • Article
  • Open Access
1,103 Views
20 Pages

Microplastic pollution is a growing global environmental and public health concern, driven by the increasing production and use of plastics. Due to their ubiquitous presence in the environment, humans and animals may be exposed to micro- and nanoplas...

  • Communication
  • Open Access
22 Citations
2,243 Views
15 Pages

30 July 2024

Increasing evidence has suggested that nanoplastic pollution has become a global concern. More importantly, transgenerational toxicity can be induced by nanoplastics at predicted environmentally relevant doses (ERDs). Considering that amino modificat...

  • Article
  • Open Access
15 Citations
3,234 Views
14 Pages

28 January 2023

Polystyrene nanoparticles are the most investigated type of nanoplastics in environmental hazard studies. It remains unclear whether nanoplastic particles pose a hazard towards aquatic organisms. Thus, it was our aim to investigate whether the existi...

  • Article
  • Open Access
3 Citations
1,879 Views
16 Pages

24 February 2025

Nanoplastics (NPs), an emerging pollutant distributed in different sizes in the aquatic environment, adversely affect aquatic ecosystems. However, knowledge of the effects of NPs of various sizes on phytoplankton, especially freshwater microalgae, is...

  • Feature Paper
  • Article
  • Open Access
33 Citations
3,329 Views
14 Pages

17 November 2022

In nematode Caenorhabditis elegans, exposure to polystyrene nanoparticles (PS-NPs) at predicted environmental concentrations can cause induction of transgenerational toxicity. However, the underlying mechanisms for toxicity formation of PS-NP in the...

  • Article
  • Open Access
28 Citations
5,094 Views
14 Pages

The ubiquitous nature of plastics, particularly nanoplastics, raises concern about their potential effects on primary producer microalgae. Currently, the impacts and potential mechanisms of nanoplastics on microalgae are not fully understood. In this...

  • Article
  • Open Access
4 Citations
2,189 Views
13 Pages

30 March 2023

The allo-tetraploid common carp encodes two duplicated fads2 genes (fads2a and fads2b) and two duplicated elovl5 genes (elovl5a and elovl5b). The coding SNPs (cSNPs) of these genes were reported to be significantly associated with the PUFA contents....

  • Article
  • Open Access
14 Citations
4,045 Views
19 Pages

22 April 2022

Mucin (Mu), a biological substance extracted from jellyfish (Aurelia aurita), was used to reduce the toxic effect of polystyrene nanoplastics (PS-NP) combined with phenanthrene (Phe) in the aquatic environment of zebrafish (Danio rerio), among other...

  • Article
  • Open Access
4 Citations
1,840 Views
17 Pages

Co-Existing Nanoplastics Further Exacerbates the Effects of Triclosan on the Physiological Functions of Human Serum Albumin

  • Yan Bao,
  • Yaoyao Wang,
  • Hongbin Liu,
  • Jing Lan,
  • Zhicai Li,
  • Wansong Zong and
  • Zongshan Zhao

16 January 2025

The potential health risks posed by the coexistence of nanoplastics (NPs) and triclosan (TCS) have garnered significant attention. However, the effects and underlying mechanisms of NPs and TCS on key functional proteins at the molecular level remain...

  • Article
  • Open Access
15 Citations
5,206 Views
12 Pages

Preparation of Novel Biodegradable Polymer Slow-Release Fertilizers to Improve Nutrient Release Performance and Soil Phosphorus Availability

  • Yang Xiang,
  • Yaqing Liu,
  • Mingshan Gong,
  • Yingfang Tong,
  • Yuhan Liu,
  • Guizhe Zhao and
  • Jianming Yang

9 May 2023

Inspired by the gradual collapse of carbon chain and the gradual release of organic elements into the external environment during the degradation of biodegradable polymers, a novel biodegradable polymer slow-release fertilizer containing nutrient nit...

  • Article
  • Open Access
7 Citations
1,858 Views
21 Pages

30 August 2024

Nano-plastics (NPs) have emerged as a pervasive global contaminant, posing significant threats to carnivorous fish, in recent years. The accumulation of polystyrene nano-plastics (PS-NPs) can cause endoplasmic reticulum (ER) stress. However, the conc...

  • Article
  • Open Access
41 Citations
4,755 Views
14 Pages

The Complex Toxicity of Tetracycline with Polystyrene Spheres on Gastric Cancer Cells

  • Xiemin Yan,
  • Yuanyuan Zhang,
  • Yuqin Lu,
  • Lei He,
  • Junhao Qu,
  • Chunxia Zhou,
  • Pengzhi Hong,
  • Shengli Sun,
  • Hui Zhao and
  • Chengyong Li
  • + 4 authors

Nowadays, microplastics (MPs) exist widely in the marine. The surface has strong adsorption capacity for antibiotics in natural environments, and the cytotoxicity of complex are poorly understood. In the study, 500 nm polystyrene (PS-MPs) and 60 nm n...

  • Article
  • Open Access
2,075 Views
21 Pages

Does the Urban Productive Safety Net Programme Alleviate Food Insecurity and Improve Education? Evidence from Tigray, Ethiopia

  • Yibrah Hagos Gebresilassie,
  • Gebremeskel Berhane Tesfay,
  • Tekeleweyni Hadush Abay and
  • Sakhile Mpungose

This study examines the effects of the urban productive safety net programme (uPSNP) on urban households’ food insecurity (FIN) and children’s school attendance in Tigray, Ethiopia. Data were collected from 333 urban households between Au...

  • Review
  • Open Access
16 Citations
5,147 Views
20 Pages

Unmasking the Invisible Threat: Biological Impacts and Mechanisms of Polystyrene Nanoplastics on Cells

  • Wenxia Bu,
  • Ye Cui,
  • Yueyuan Jin,
  • Xuehai Wang,
  • Mengna Jiang,
  • Ruiyao Huang,
  • JohnPaul Otuomasiri Egbobe,
  • Xinyuan Zhao and
  • Juan Tang

14 December 2024

Polystyrene nanoplastics (PS-NPs), a pervasive component of plastic pollution, have emerged as a significant environmental and health threat due to their microscopic size and bioaccumulative properties. This review systematically explores the biologi...

  • Article
  • Open Access
5 Citations
2,039 Views
15 Pages

Polystyrene Nanomicroplastics Aggravate Ammonia-Induced Neurotoxic Effects in Zebrafish Embryos

  • Dan Xing,
  • Wenting Zheng,
  • Huiming Zhou,
  • Guangyu Li,
  • Yan Li,
  • Jingwen Jia,
  • Haoling Liu,
  • Ning Luan and
  • Xiaolin Liu

26 November 2024

The highly hazardous chemical ammonia has been proven to be absorbed by nanoparticles, thereby exerting highly toxic effects on aquatic organisms. As a ubiquitous pollutant in aquatic environments, polystyrene nanomicroplastics (PSNPs) have shown str...

  • Article
  • Open Access
6 Citations
2,146 Views
19 Pages

Impact of Short-Term Exposure to Non-Functionalized Polystyrene Nanoparticles on DNA Methylation and Gene Expression in Human Peripheral Blood Mononuclear Cells

  • Kinga Malinowska,
  • Kateryna Tarhonska,
  • Marek Foksiński,
  • Paulina Sicińska,
  • Ewa Jabłońska,
  • Edyta Reszka,
  • Ewelina Zarakowska,
  • Daniel Gackowski,
  • Karolina Górecka and
  • Bożena Bukowska
  • + 1 author

28 November 2024

The aim of the present study was to investigate the concentration- and size-dependent effects of non-functionalized polystyrene nanoparticles (PS-NPs) of varying diameters (29 nm, 44 nm, and 72 nm) on specific epigenetic modifications and gene expres...

  • Article
  • Open Access
13 Citations
3,717 Views
17 Pages

The Potential Mechanisms Involved in the Disruption of Spermatogenesis in Mice by Nanoplastics and Microplastics

  • Yixian Wen,
  • Jing Cai,
  • Huilian Zhang,
  • Yi Li,
  • Manyao Yu,
  • Jinyi Liu and
  • Fei Han

Background: Plastic-based products are ubiquitous due to their tremendous utility in our daily lives. Nanoplastic (NP) and microplastic (MP) pollution has become a severe threat to the planet and is a growing concern. It has been widely reported that...

  • Article
  • Open Access
4 Citations
2,452 Views
20 Pages

15 October 2024

Land degradation is a critical issue in Ethiopia, exacerbating food insecurity by reducing agricultural productivity. Soil and water conservation (SWC) practices are essential to control erosion and increase food production. However, there is a lack...

  • Article
  • Open Access
415 Views
21 Pages

Polystyrene Nanoplastic Exposure Causes Reprogramming of Anti-Oxidative Genes Hmox1 and Sod3 by Inhibiting Nuclear Receptor RORγ in the Mouse Liver

  • Pingyun Ding,
  • Madesh Muniyappan,
  • Chuyang Zhu,
  • Chenhui Li,
  • Saber Y. Adam,
  • Yu Wang,
  • Thobela Louis Tyasi,
  • Peng Yuan,
  • Ping Hu and
  • Demin Cai
  • + 1 author

13 January 2026

Plastic pollution is acknowledged as a serious problem for ecosystems. Among these plastics, polystyrene nanoplastics (PS-NPs) are emerging environmental pollutants, and their biological effects on hepatotoxicity are the least explored. Therefore, th...

  • Article
  • Open Access
38 Citations
5,217 Views
15 Pages

With the ongoing commercialization, human exposure to plastic nanoparticles will dramatically increase, and evaluation of their potential toxicity is essential. There is an ongoing discussion on the human health effects induced by plastic particles....

  • Article
  • Open Access
27 Citations
3,275 Views
18 Pages

In Vitro Nano-Polystyrene Toxicity: Metabolic Dysfunctions and Cytoprotective Responses of Human Spermatozoa

  • Martina Contino,
  • Greta Ferruggia,
  • Stefania Indelicato,
  • Roberta Pecoraro,
  • Elena Maria Scalisi,
  • Giovanni Bracchitta,
  • Jessica Dragotto,
  • Antonio Salvaggio and
  • Maria Violetta Brundo

20 April 2023

The ubiquitous spread of Polystyrene nanoplastics (PS-NPs) has rendered chronic human exposure an unavoidable phenomenon. The biodistribution of such particles leads to bioaccumulation in target organs including the testis, the site of sperm maturati...

  • Article
  • Open Access
2 Citations
2,943 Views
13 Pages

Combined Toxicity of Polystyrene Nanoplastics and Pyriproxyfen to Daphnia magna

  • Hua-Bing Jia,
  • Yu-Hang Zhang,
  • Rong-Yao Gao,
  • Xiao-Jing Liu,
  • Qian-Qian Shao,
  • Ya-Wen Hu,
  • Li-Min Fu and
  • Jian-Ping Zhang

13 May 2024

In recent years, the adverse effects of nanoplastics (NPs) and pyriproxyfen on aquatic environments have attracted widespread attention. However, research on their combined exposure to aquatic organisms could be more extensive. This work evaluated th...

  • Article
  • Open Access
481 Views
21 Pages

Transcriptome and Gene Family Analyses Reveal the Physiological and Immune Regulatory Mechanisms of Channa maculata Larvae in Response to Nanoplastic-Induced Oxidative Stress

  • Ziwen Yang,
  • Dandan Gao,
  • Yuntao Lu,
  • Yang Zou,
  • Yueying Deng,
  • Luping Liu,
  • Qing Luo,
  • Haiyang Liu,
  • Shuzhan Fei and
  • Mi Ou
  • + 2 authors

19 January 2026

The increasing accumulation of plastic debris in aquatic environments has raised concerns about the ecotoxicological effects of polystyrene nanoplastics (PSNPs). This study examined PSNPs toxicity during a critical developmental stage by exposing 15...

  • Article
  • Open Access
6 Citations
2,557 Views
13 Pages

31 January 2025

Different pollutants often coexist in natural environments, making it crucial to monitor and study the ecotoxicological effects of composite pollutants in aquatic environments. Nanoplastics and heavy metals are emerging environmental pollutants that...

  • Article
  • Open Access
3 Citations
1,443 Views
13 Pages

Effects of Low-Molecular-Weight Organic Acids on the Transport of Polystyrene Nanoplastics in Saturated Goethite-Coated Sand Columns

  • Feiyu Chen,
  • Xiaocheng Peng,
  • Xiaocheng Liu,
  • Biaodian Chen,
  • Lidong Chen,
  • Taotao Lu and
  • Yi Gong

5 December 2024

The widespread use of nanoplastics inevitably contributes to pollution in aquatic environments and soils. Therefore, it is crucial to understand how these particles migrate in soils with diverse organic matter. This study investigated the effects of...

  • Article
  • Open Access
3 Citations
1,236 Views
23 Pages

Nanoplastics Elicit Stage-Specific Physiological, Biochemical, and Gut Microbiome Responses in a Freshwater Mussel

  • Yangli Chi,
  • Hui Zhang,
  • Jian Gao,
  • Liang Wan,
  • Yiying Jiao,
  • Heyun Wang,
  • Mingjun Liao and
  • Ross N. Cuthbert

5 May 2025

Mussels are highly efficient filter feeders, playing a crucial role in managing eutrophication and assessing pollution. Although research on nanoplastic (NP) toxicity in marine organisms is expanding, studies on freshwater species remain limited desp...

  • Article
  • Open Access
3 Citations
1,448 Views
18 Pages

Exposure to Nanoplastics During Pregnancy Induces Brown Adipose Tissue Whitening in Male Offspring

  • Zhaoping Shen,
  • Kai Tian,
  • Jiayi Tang,
  • Lin Wang,
  • Fangsicheng Zhang,
  • Lingjuan Yang,
  • Yufei Ge,
  • Mengna Jiang,
  • Xinyuan Zhao and
  • Xiaoke Wang
  • + 2 authors

27 February 2025

Background: Polystyrene nanoplastics (PSNPs) have been recognized as emerging environmental pollutants with potential health impacts, particularly on metabolic disorders. However, the mechanism by which gestational exposure to PSNPs induces obesity i...

  • Review
  • Open Access
1,512 Views
26 Pages

Polystyrene Nanoplastics in Human Gastrointestinal Models—Cellular and Molecular Mechanisms of Toxicity

  • Agata Kustra,
  • Kamila Maliszewska-Olejniczak,
  • Anna Sekrecka-Belniak,
  • Bogusz Kulawiak and
  • Piotr Bednarczyk

4 December 2025

Plastic pollution is a growing environmental and health issue due to the increasing presence of micro- and nanoplastics in terrestrial and aquatic ecosystems. Polystyrene nanoplastics (PS-NPs) are among the most extensively studied because of their w...

  • Article
  • Open Access
22 Citations
2,146 Views
13 Pages

7 June 2024

Transgenerational nanoplastic toxicity could be detected in Caenorhabditis elegans after exposure at the parental generation (P0-G); however, the underlying mechanisms remain largely unclear. We aimed to examine the role of germline nuclear hormone r...

  • Feature Paper
  • Article
  • Open Access
4 Citations
1,905 Views
15 Pages

Effects of Sub-Chronic Exposure to Polystyrene Nanoplastics on Lipid and Antioxidant Metabolism in Sparus aurata

  • Ekemini Okon,
  • Irene Brandts,
  • Hayam Djafar,
  • Asta Tvarijonaviciute,
  • Joan Carles Balasch and
  • Mariana Teles

14 February 2025

Nanoplastics (NPs) can cross cellular membranes and affect cellular performance. This study aims to determine the effects of polystyrene NPs (PS-NPs, 44 nm) on gilthead seabream (Sparus aurata) exposed for 14 days to 100 μg/L PS-NPs. The results s...

  • Article
  • Open Access
17 Citations
5,021 Views
13 Pages

18 May 2023

Nanoplastics have gradually become a concern due to the wide use of plastics. Nanoplastics in aqueous phase can be exposed to users through water supply networks and cannot be efficiently removed by conventional water treatment processes. This work s...

  • Article
  • Open Access
382 Citations
20,099 Views
29 Pages

Nanoplastics Cause Neurobehavioral Impairments, Reproductive and Oxidative Damages, and Biomarker Responses in Zebrafish: Throwing up Alarms of Wide Spread Health Risk of Exposure

  • Sreeja Sarasamma,
  • Gilbert Audira,
  • Petrus Siregar,
  • Nemi Malhotra,
  • Yu-Heng Lai,
  • Sung-Tzu Liang,
  • Jung-Ren Chen,
  • Kelvin H.-C. Chen and
  • Chung-Der Hsiao

19 February 2020

Plastic pollution is a growing global emergency and it could serve as a geological indicator of the Anthropocene era. Microplastics are potentially more hazardous than macroplastics, as the former can permeate biological membranes. The toxicity of mi...

  • Article
  • Open Access
13 Citations
3,021 Views
17 Pages

Vitamin E Mitigates Polystyrene-Nanoplastic-Induced Visual Dysfunction in Zebrafish Larvae

  • Febriyansyah Saputra,
  • Azzah Dyah Pramata,
  • Agoes Soegianto and
  • Shao-Yang Hu

30 January 2025

Vitamin E (VitE), a potent antioxidant, has demonstrated significant potential in mitigating oxidative stress and cellular damage, making it a valuable agent for countering environmental toxicities, including those caused by polystyrene nanoplastics...

  • Article
  • Open Access
55 Citations
6,129 Views
10 Pages

The Biological Effects of Polystyrene Nanoplastics on Human Peripheral Blood Lymphocytes

  • Devojit Kumar Sarma,
  • Ruchi Dubey,
  • Ravindra M. Samarth,
  • Swasti Shubham,
  • Pritom Chowdhury,
  • Manoj Kumawat,
  • Vinod Verma,
  • Rajnarayan R. Tiwari and
  • Manoj Kumar

11 May 2022

Environmental exposure to microplastics (MPs) and nanoplastics (NPs) is an increasing concern from human health perspectives. Little information on the genotoxic and cytotoxic potential of NP particles in human cells is available. We aimed to assess...

  • Article
  • Open Access
6 Citations
1,787 Views
17 Pages

Adverse Effect of Polystyrene Nanoplastics in Impairing Glucose Metabolism in Liver Injury

  • Raden Joko Kuncoroningrat Susilo,
  • Manikya Pramudya,
  • Firli Rahmah Primula Dewi,
  • Windy Seftiarini,
  • Dewi Hidayati,
  • Aunurohim Aunurohim,
  • Vuanghao Lim,
  • Mochammad Aqilah Herdiansyah and
  • Alfiah Hayati

Polystyrene nanoplastics (PS-NPs) are result from the degradation of plastic and have diameters ranging from 1 nm to 100 nm. The objective of this study is to provide information on the adverse effects of PS-NPs with in vitro and in vivo analyses of...

  • Article
  • Open Access
664 Views
13 Pages

Effects of Short-Term Exposure to Polystyrene Nanoplastics on the Nervous System: Calcium Homeostasis, BDNF and Synaptic Plasticity

  • Yiming Zhao,
  • Licheng Yan,
  • Yizhe Wei,
  • Jianping Ma,
  • Jiang Chen,
  • Xuan Liu,
  • Yanan Mi,
  • Bingyan Wang,
  • Leili Zhang and
  • Bencheng Lin
  • + 1 author

17 February 2026

(1) Background: The increasing environmental concentration of polystyrene nanoplastics (PS-NPs) may pose a risk of human exposure and health threats. Previous studies have demonstrated that exposure to PS-NPs poses a threat to neural synaptic plastic...

  • Article
  • Open Access
6 Citations
3,198 Views
20 Pages

Plastic Fly: What Drosophila melanogaster Can Tell Us about the Biological Effects and the Carcinogenic Potential of Nanopolystyrene

  • Massimo Aloisi,
  • Daniela Grifoni,
  • Osvaldo Zarivi,
  • Sabrina Colafarina,
  • Patrizia Morciano and
  • Anna Maria Giuseppina Poma

Today, plastic pollution is one of the biggest threats to the environment and public health. In the tissues of exposed species, micro- and nano-fragments accumulate, leading to genotoxicity, altered metabolism, and decreased lifespan. A model to inve...

  • Article
  • Open Access
1 Citations
700 Views
15 Pages

Superoxide Dismutase 3 Deficiency Disrupts the Regulation of Oxidative Stress Caused by Polystyrene Nanoplastics

  • Yugyeong Sim,
  • Jin-Hyoung Kim,
  • Jeong-Soo Lee,
  • Jinyoung Jeong and
  • Hyun-Ju Cho

19 November 2025

Nanoplastics have been recognized as emerging pollutants posing potential risks to ecosystems and human health. They are now detected ubiquitously in the environment and even human tissues, where their small size allows for tissue accumulation and ce...

  • Article
  • Open Access
6 Citations
2,899 Views
15 Pages

Discrepancy of Growth Toxicity of Polystyrene Nanoplastics on Soybean (Glycine max) and Mung Bean (Vigna radiata)

  • Dan Su,
  • Wangwang Li,
  • Zhaowei Zhang,
  • Hui Cai,
  • Le Zhang,
  • Yuanlong Sun,
  • Xiaoning Liu and
  • Zhiquan Tian

17 February 2024

Nanoplastics, as a hot topic of novel contaminants, lack extensive concern in higher plants; especially the potential impact and mechanism of nanoplastics on legume crops remains elusive. In this study, the toxicity of polystyrene nanoplastics (PS-NP...

  • Article
  • Open Access
74 Citations
5,656 Views
17 Pages

The ocean contamination caused by micro- and nano-sized plastics is a matter of increasing concern regarding their potential effects on marine organisms. This study compared the effects of a 21-day exposure to 1.5, 15, and 150 ng/L of polystyrene mic...

  • Article
  • Open Access
8 Citations
2,086 Views
20 Pages

Effects of Polystyrene Nanoplastics on Oxidative Stress, Blood Biochemistry, and Digestive Enzyme Activity in Goldfish (Carassius auratus)

  • Sasan Azarm-Karnagh,
  • Masoud Sattari,
  • Mahdi Banaee,
  • Behzad Shirkavand Hadavand and
  • Francesca Falco

24 April 2025

Plastic pollution in aquatic ecosystems has become a global concern, and nanoplastics, due to their small size and high penetration potential, pose significant risks to aquatic organisms. This study aimed to evaluate the effects of polystyrene nanopl...

  • Article
  • Open Access
523 Views
16 Pages

Evaluation of Polystyrene Nanoplastics Induced Cardiotoxicity Under Different Dietary Patterns in Mice

  • Shuyi Wang,
  • Tao Wu,
  • Jie Dai,
  • Xialei Liu,
  • Lan He,
  • Yijun Dong,
  • Lina Zhao and
  • Na Li

31 December 2025

Background: Nanoplastics (NPs), as emerging foodborne contaminants, can accumulate in the heart and induce toxic effects. However, whether NPs exert differential cardiac impacts depending on dietary habits remains unclear. Methods: In this study, mic...

  • Article
  • Open Access
125 Citations
8,142 Views
16 Pages

Long-Term Effects of Polystyrene Nanoplastics in Human Intestinal Caco-2 Cells

  • Josefa Domenech,
  • Mariana de Britto,
  • Antonia Velázquez,
  • Susana Pastor,
  • Alba Hernández,
  • Ricard Marcos and
  • Constanza Cortés

1 October 2021

The increasing presence of micro- and nanoplastics (MNPLs) in the environment, and their consequent accumulation in trophic niches, could pose a potential health threat to humans, especially due to their chronic ingestion. In vitro studies using huma...

  • Article
  • Open Access
962 Views
19 Pages

7 June 2025

Human exposure to micro- and nanoplastic (MNP) has become an increasing concern due to its accumulation in the environment and human body. In the human organism, MNP accumulates in various tissues, including the central nervous system, where it is as...

  • Article
  • Open Access
11 Citations
3,714 Views
14 Pages

17 May 2024

Nanoplastics, created by the fragmentation of larger plastic debris, are a serious pollutant posing substantial environmental and health risks. Here, we developed a polystyrene nanoparticle (PS-NP) exposure model during mice pregnancy to explore thei...

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