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179 Results Found

  • Review
  • Open Access
6 Citations
2,661 Views
17 Pages

Advances in Microvascular Reconstruction of the Orbit and Beyond: Considerations and a Checklist for Decision-Making

  • Gian Battista Bottini,
  • Veronika Joos,
  • Christoph Steiner,
  • Katharina Zeman-Kuhnert and
  • Alexander Gaggl

14 May 2024

This paper aims to discuss the microvascular reconstruction of the orbit and adjacent regions and to propose a checklist to aid the reconstructive surgeon in this challenging undertaking. The discussion is based on a literature review that includes 3...

(This article belongs to the Special Issue New Advances in Oral and Facial Surgery)
  • Article
  • Open Access
6 Citations
2,034 Views
11 Pages

Dental Rehabilitation After Microvascular Reconstruction of Segmental Jaw Defects: A Ten-Year Follow-Up

  • Katharina Zeman-Kuhnert,
  • Alexander J. Gaggl,
  • Gian B. Bottini,
  • Benjamin Walch and ,
  • Christoph Steiner,
  • Georg Zimmermann and
  • Christian Brandtner
  • + 2 authors+ 0 author

19 January 2025

Background/Objectives: Defects in maxillary and mandibular continuity are common in maxillofacial practice. They can occur after trauma, osteonecrosis, congenital jaw deformities, or surgical resection of benign or malignant tumours. Reconstruction w...

(This article belongs to the Special Issue Clinical Progress in Microsurgical Reconstruction)
  • Article
  • Open Access
3 Citations
1,321 Views
11 Pages

Quality of Life After Microvascular Alveolar Ridge Reconstruction with Subsequent Dental Rehabilitation

  • Katharina Zeman-Kuhnert,
  • Alexander J. Gaggl,
  • Gian B. Bottini,
  • Joern Wittig and ,
  • Christoph Steiner,
  • Wanda Lauth and
  • Christian Brandtner
  • + 2 authors+ 0 author

18 October 2024

Background/Objectives: Defects in maxillary and mandibular alveolar ridges are common in maxillofacial practice. Reconstruction with microvascular bone grafts and subsequent prosthetic rehabilitation is the gold standard treatment. This study investi...

(This article belongs to the Special Issue Clinical Advances in Reconstructive Surgery: Innovations and Outcomes for Improved Patient Care)
  • Article
  • Open Access
9 Citations
3,309 Views
17 Pages

S-Propargyl-Cysteine Ameliorates Peripheral Nerve Injury through Microvascular Reconstruction

  • Haiyan Xi,
  • Chenye Wang,
  • Qixiu Li,
  • Qing Ye and ,
  • Yizhun Zhu and
  • Yicheng Mao
  • + 1 author+ 0 author

28 January 2023

Microvascular reconstruction is essential for peripheral nerve repair. S-Propargyl-cysteine (SPRC), the endogenous hydrogen sulfide (H2S) donor, has been reported to promote angiogenesis. The aim of this study is to utilize the pro-angiogenic ability...

(This article belongs to the Special Issue Hydrogen Sulfide and Diseases)
  • Article
  • Open Access
32 Citations
1,418 Views
9 Pages

Microvascular Free Tissue Transfer in the Reconstruction of Scalp and Lateral Temporal Bone Defects

  • Daniel A. O'Connell,
  • Marita S. Teng,
  • Eduardo Mendez and
  • Neal D. Futran

Defects of the scalp and lateral temporal bone (LTB) represent a unique challenge to the reconstructive surgeon. Simple reconstructive methods such as skin grafts, locoregional flaps, or tissue expanders are often not feasible due to a myriad of reas...

  • Review
  • Open Access
2 Citations
1,961 Views
13 Pages

Background: Steal syndrome in the setting of microvascular reconstruction refers to a phenomenon whereby blood flow is diverted from the native tissue to the free flap, leading to ischemia and potential limb loss. In the present study, we aim to comp...

(This article belongs to the Special Issue Surgical Wound Infections and Management)
  • Article
  • Open Access
522 Views
14 Pages

Age-Associated Donor-Site Selection Patterns in Pediatric Maxillary Microvascular Reconstruction: A 14-Year Single-Center Experience

  • Dominika Lech,
  • Robert Maksymowicz,
  • Jeremi Matysek,
  • Aleksandra Strzelecka and ,
  • Cyprian Strączek,
  • Marcin Kozakiewicz,
  • Łukasz Krakowczyk and
  • Krzysztof Dowgierd
  • + 3 authors+ 0 author

15 May 2026

Background: Reconstruction of maxillary defects in pediatric patients presents unique challenges related to craniofacial growth, functional rehabilitation, and long-term treatment planning. Although microvascular free-flap reconstruction is establish...

(This article belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
  • Article
  • Open Access
7 Citations
2,207 Views
10 Pages

Microvascular Muscle vs. Fascio-Cutaneous Free Flaps for Reconstruction of Plantar Load-Bearing Foot Defects—An International Survey

  • Sinan Mert,
  • Paul I. Heidekrueger,
  • Benedikt Fuchs,
  • Tim Nuernberger and ,
  • Elisabeth M. Haas-Lützenberger,
  • Riccardo E. Giunta,
  • Denis Ehrl and
  • Wolfram Demmer
  • + 3 authors+ 0 author

24 February 2024

Background: The reconstruction of plantar load-bearing foot defects faces many plastic surgeons with a major challenge. The optimal patient- and defect-oriented reconstructive strategy must be selected. Methods: To analyze the current trends and reco...

(This article belongs to the Special Issue Clinical Advances in Plastic Surgery)
  • Article
  • Open Access
2 Citations
2,161 Views
10 Pages

Influence of Renal Impairment on the Success of Reconstruction Using Microvascular Grafts—A Retrospective Study of 251 Free Flaps

  • Henriette L. Moellmann,
  • Nadia Karnatz,
  • Ilkan Degirmenci,
  • Antonina Gyurova and ,
  • Lorenz Sellin and
  • Majeed Rana
  • + 1 author+ 0 author

20 October 2022

Background: In head and neck surgery, reconstruction using microvascular grafts is a successful method for functional and aesthetic restoration. Due to technological advances and medical care, the number of patients with comorbidities and diseases re...

(This article belongs to the Section Methodology, Drug and Device Discovery)
  • Article
  • Open Access
34 Citations
5,014 Views
12 Pages

Muscle vs. Fasciocutaneous Microvascular Free Flaps for Lower Limb Reconstruction: A Meta-Analysis of Comparative Studies

  • Vladimir Mégevand,
  • Domizio Suva,
  • Morad Mohamad,
  • Didier Hannouche and ,
  • Daniel F. Kalbermatten and
  • Carlo M. Oranges
  • + 1 author+ 0 author

11 March 2022

(1) Background: Lower extremity microvascular reconstruction aims at restoring function and preventing infection while ensuring optimal cosmetic outcomes. Muscle (M) or fasciocutaneous (FC) free flaps are alternatively used to treat similar condition...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
4 Citations
2,934 Views
19 Pages

Long-Term Functional Outcomes and Quality of Life After Microvascular Reconstruction of Ankle and Foot Defects: A Monocentric Controlled Cohort Study

  • Sarah Pfeifenberger,
  • Andrzej Hecker,
  • Nikolaus Watzinger,
  • Maximilian Moshammer and ,
  • Anna-Lisa Pignet,
  • Alexander Draschl,
  • Ron Martin,
  • Charalambos Louca,
  • Lars-Peter Kamolz and
  • Stephan Spendel
  • + 5 authors+ 0 author

13 May 2025

Background: Defects of the foot and ankle area pose a significant challenge for both patients and surgeons. While the primary objective of microvascular free flap reconstructions of lower leg defects is limb preservation, there should be an effort to...

(This article belongs to the Special Issue Novel Approaches in Plastic and Reconstructive Surgery to Improve Quality of Life)
  • Article
  • Open Access
19 Citations
3,046 Views
10 Pages

19 August 2022

Extensive defects in the head and neck area often require the use of advanced free flap reconstruction techniques. In this study, the thoracodorsal perforator-scapular free flap technique based on the angular artery (TDAP-Scap-aa flap) was postoperat...

(This article belongs to the Section Oncology)
  • Review
  • Open Access
2 Citations
2,224 Views
14 Pages

26 February 2024

The field of microsurgical head and neck reconstruction has witnessed tremendous advancements in recent years. While the historic goals of reconstruction were simply to maximize flap survival, optimizing both aesthetic and functional outcomes has now...

(This article belongs to the Special Issue Reconstructive Microsurgery: Challenges and New Perspectives)
  • Article
  • Open Access
2 Citations
1,269 Views
9 Pages

Microvascular Reconstructions in Elderly Patients with Oral Squamous Cell Carcinoma—Too Old for Surgical Treatment?

  • Anne Radermacher,
  • Dominik Horn,
  • Michael Fehrenz,
  • Karl Semmelmayer and ,
  • Oliver Ristow,
  • Michael Engel,
  • Jürgen Hoffmann,
  • Kolja Freier and
  • Julius Moratin
  • + 4 authors+ 0 author

Study Design: Retrospective cohort study. Objective: A major risk factor for oral squamous cell carcinoma (OSCC) is advanced age. Ablative surgery combined with microvascular reconstruction has become routine for OSCC. Nevertheless, there is an inter...

  • Article
  • Open Access
7 Citations
2,332 Views
11 Pages

The Controlling Nutritional Status (CONUT) Score for Prediction of Microvascular Flap Complications in Reconstructive Surgery

  • Rihards P. Rocans,
  • Janis Zarins,
  • Evita Bine,
  • Renars Deksnis and ,
  • Margarita Citovica,
  • Simona Donina and
  • Biruta Mamaja
  • + 2 authors+ 0 author

20 July 2023

Microvascular flap surgery is a widely acknowledged procedure for significant defect reconstruction. Multiple flap complication risk factors have been identified, yet there are limited data on laboratory biomarkers for the prediction of flap loss. Th...

(This article belongs to the Special Issue Reconstructive Microsurgery: Challenges and New Perspectives)
  • Review
  • Open Access
23 Citations
1,605 Views
11 Pages

Thromboprophylaxis in Head and Neck Microvascular Reconstruction

  • Manoj Abraham,
  • Arvind Badhey,
  • Shirley Hu,
  • Sameep Kadakia and ,
  • J. K. Rasamny,
  • Augustine Moscatello and
  • Yadranko Ducic
  • + 2 authors+ 0 author

Head and neck patients undergoing microvascular reconstruction are at high risk for thromboembolism. While the prevention of thromboembolism has become an essential aspect of care, within the field of microsurgery, concern for anastomotic complicatio...

  • Article
  • Open Access
5 Citations
2,091 Views
13 Pages

8 May 2024

Background: Flap perfusion is a prerequisite for microvascular free flap survival and a parameter routinely used for flap monitoring. The aim of this study was to investigate the influence of the anastomosis recipient vessel on flap perfusion. Method...

(This article belongs to the Section Otolaryngology)
  • Article
  • Open Access
1 Citations
1,260 Views
12 Pages

Early Postoperative Increase in Transforming Growth Factor Beta-1 Predicts Microvascular Flap Loss in Reconstructive Surgery: A Prospective Cohort Study

  • Rihards Peteris Rocans,
  • Janis Zarins,
  • Evita Bine,
  • Insana Mahauri and ,
  • Renars Deksnis,
  • Margarita Citovica,
  • Simona Donina,
  • Sabine Gravelsina,
  • Anda Vilmane and
  • Biruta Mamaja
  • + 7 authors+ 2 authors

Background and Objectives: Microvascular flap surgery is a widely used reconstructive technique for the repair of various defects. Biomarkers have become an essential tool for monitoring flap viability, early detection of complications, and predictio...

(This article belongs to the Special Issue New Insights into Plastic and Reconstructive Surgery)
  • Review
  • Open Access
7 Citations
5,610 Views
14 Pages

Innovative Strategies in Microvascular Head and Neck Reconstruction

  • Z-Hye Lee,
  • Tarek Ismail,
  • John W. Shuck and
  • Edward I. Chang

24 June 2023

The field of reconstructive microsurgery has witnessed considerable advancements over the years, driven by improvements in technology, imaging, surgical instruments, increased understanding of perforator anatomy, and experience with microsurgery. How...

(This article belongs to the Special Issue Latest Trends in Reconstructive Microsurgery: From Modification to Innovation)
  • Review
  • Open Access
4 Citations
3,150 Views
10 Pages

2 October 2023

Reconstruction of the midface represents a challenge for reconstructive microsurgeons given the formidable task of restoring both aesthetics and functionality. In particular, preservation of proper globe positioning and maintaining normal vision are...

(This article belongs to the Special Issue New Trends in Craniomaxillofacial Surgery)
  • Article
  • Open Access
6 Citations
3,268 Views
12 Pages

Maxillofacial Microvascular Free-Flap Reconstructions in Pediatric and Young Adult Patients—Outcomes and Potential Factors Influencing Success Rate

  • Dominika Lech,
  • Jeremi Matysek,
  • Robert Maksymowicz,
  • Cyprian Strączek and ,
  • Robert Marguła,
  • Łukasz Krakowczyk,
  • Marcin Kozakiewicz and
  • Krzysztof Dowgierd
  • + 3 authors+ 0 author

30 March 2024

Background: Maxillofacial microvascular free-flap reconstructions are significant interventions in the management of congenital defects, traumatic injuries, malignancies, and iatrogenic complications in pediatric and young adult patients. Craniofacia...

(This article belongs to the Special Issue Reconstructive Microsurgery: Challenges and New Perspectives)
  • Article
  • Open Access
1 Citations
1,999 Views
12 Pages

Microvascular Free Flap Reconstruction After Salvage Total Laryngectomy: Experience of the Verona University

  • Riccardo Nocini,
  • Giulia Gobbo,
  • Valerio Arietti,
  • Gabriele Molteni and ,
  • Luca Sacchetto,
  • Giorgio Barbera,
  • Gianluca Colapinto,
  • Massimo Del Fabbro and
  • Funda Goker
  • + 4 authors+ 0 author

10 October 2025

Objective: This article evaluates the reconstructive potential and functional outcomes, as well as the risks and potential perioperative complications of using free flaps in patients with advanced-stage malignant laryngeal neoplasms who require salva...

(This article belongs to the Section General Surgery)
  • Article
  • Open Access
559 Views
18 Pages

Perioperative Predictors of Complications and Flap Loss in Microvascular Reconstructive Surgery: The Role of Fluid Balance, Crystalloid Administration and Operative Time

  • Saeed Torabi,
  • Philipp K. Omuro,
  • Remco Overbeek,
  • Elisabeth H. Adam and ,
  • Sandra E. Stoll,
  • Tobias Kammerer,
  • Carolin Schroeder,
  • Matthias Zirk,
  • Andrea U. Steinbicker and
  • Max Zinser
  • + 6 authors+ 1 author

10 July 2026

Background: Perioperative fluid therapy plays a critical role in the outcome of microvascular free-flap surgery. While both inadequate and excessive fluid administration may impair flap perfusion and systemic recovery, the impact of fluid balance and...

(This article belongs to the Section Anesthesiology)
  • Article
  • Open Access
7 Citations
2,614 Views
12 Pages

The Perfect Timing—Immediate versus Delayed Microvascular Reconstruction of the Mandible

  • Daniel G. E. Thiem,
  • Fabia Siegberg,
  • Shankeeth Vinayahalingam,
  • Sebastian Blatt and ,
  • Maximilian Krüger,
  • Bernd Lethaus,
  • Bilal Al-Nawas,
  • Rüdiger Zimmerer and
  • Peer W. Kämmerer
  • + 4 authors+ 0 author

28 February 2024

In this retrospective study, the clinical and economic implications of microvascular reconstruction of the mandible were assessed, comparing immediate versus delayed surgical approaches. Utilizing data from two German university departments for oral...

(This article belongs to the Special Issue Clinical and Translational Research in Head and Neck Cancer)
  • Article
  • Open Access
6 Citations
2,264 Views
10 Pages

Long-Term Follow-Up of Computer-Assisted Microvascular Mandibular Reconstruction: A Retrospective Study

  • Erika Crosetti,
  • Pierluigi Tos,
  • Mattia Berrone,
  • Bruno Battiston and ,
  • Giulia Arrigoni and
  • Giovanni Succo
  • + 1 author+ 0 author

3 July 2024

Background: Virtual surgical planning has become a well-established practice in head and neck surgery. In oncological surgery, it permits the achievement of safe margins resections and ensures functional reconstructions and optimal esthetic outcomes....

(This article belongs to the Special Issue New Advances in Oral and Facial Surgery)
  • Article
  • Open Access
1,943 Views
10 Pages

18 January 2025

Background. Removal of the rib and adjacent cartilage is a common step for exposure of the recipient chest vessels in free-flap breast reconstructions. However, this adds both short- and long-term morbidity to the procedure. We describe our experienc...

(This article belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
  • Article
  • Open Access
11 Citations
2,871 Views
13 Pages

Long-Term Outcomes of Dental Rehabilitation and Quality of Life after Microvascular Alveolar Ridge Reconstruction in Patients with Head and Neck Cancer

  • Katharina Zeman-Kuhnert,
  • Alexander J. Gaggl,
  • Gian B. Bottini,
  • Joern Wittig and ,
  • Georg Zimmermann,
  • Christoph Steiner,
  • Wanda Lauth and
  • Christian Brandtner
  • + 3 authors+ 0 author

25 May 2024

Background/Objectives: Dental rehabilitation after extended tumour resection and jaw reconstruction is challenging. The present study aimed to report the prosthetic outcome and quality of life (QoL) in patients with head and neck cancer (HNC) after m...

(This article belongs to the Special Issue New Advances in Oral and Facial Surgery)
  • Article
  • Open Access
17 Citations
2,911 Views
12 Pages

15 August 2023

Significant advances in reconstructive head and neck surgery with free microvascular flaps have had a positive impact on esthetic outcomes and quality of life. However, complications still occur in some patients. This study investigated the influence...

(This article belongs to the Section Otolaryngology)
  • Study Protocol
  • Open Access
2 Citations
2,818 Views
11 Pages

Enhancing Anticoagulation Monitoring and Therapy in Patients Undergoing Microvascular Reconstruction in Maxillofacial Surgery: A Prospective Observational Trial

  • Tom A. Schröder,
  • Henry Leonhardt,
  • Dominik Haim,
  • Christian Bräuer and ,
  • Kiriaki K. Papadopoulos,
  • Oliver Vicent,
  • Andreas Güldner,
  • Martin Mirus,
  • Jürgen Schmidt and
  • Lars Heubner
  • + 12 authors+ 7 authors

27 July 2022

Background: In reconstructive surgery, loss of a microvascular free flap due to perfusion disorders, especially thrombosis, is a serious complication. In recent years, viscoelastic testing (VET) has become increasingly important in point-of-care (POC...

  • Article
  • Open Access
5 Citations
3,509 Views
11 Pages

13 November 2023

(1) Background: The current landscape of midface reconstruction is marked by ongoing evolution, with notable advancements in surgical techniques, microvascular procedures, and the implementation of multidisciplinary approaches, all of which have sign...

(This article belongs to the Special Issue Updates and Challenges in Maxillo-Facial Surgery)
  • Article
  • Open Access
2 Citations
1,815 Views
12 Pages

Microvascular ALT-Flap Reconstruction for Distal Forearm and Hand Defects: Outcomes and Single-Case Application of a Bone-Anchored Venous Anastomosis

  • Adrian Matthias Vater,
  • Matthias Michael Aitzetmüller-Klietz,
  • Philipp Edmund Lamby,
  • Julia Stanger and ,
  • Rainer Meffert,
  • Karsten Schmidt,
  • Michael Georg Jakubietz and
  • Rafael Gregor Jakubietz
  • + 3 authors+ 0 author

26 September 2025

Background: Reconstruction of distal forearm and hand soft tissue defects remains a complex surgical challenge due to the functional and aesthetic significance of the region. Several flap options have been established such as the posterior interosseo...

(This article belongs to the Special Issue Microsurgery: Current and Future Challenges)
  • Case Report
  • Open Access
2 Citations
547 Views
11 Pages

Staged Head and Neck Reconstruction: Heresy or a Reasoned Approach in a Select Group of Patients?

  • Mark L. Urken,
  • Quinn O’Malley,
  • Mykayla Sandler,
  • Monica H. Xing and ,
  • Edward Ansari,
  • Neil Mundi,
  • Daniel Buchbinder,
  • Eran Alon and
  • Devin Okay
  • + 4 authors+ 0 author

Study Design: case series. Objective: The restoration of defects in a single procedure with microvascular free flap reconstruction has become a mainstay of head and neck surgery. Yet in patients with complex defects and pre-existing comorbid medical...

  • Article
  • Open Access
4 Citations
2,031 Views
10 Pages

Von Willebrand Factor Antigen, Biomarkers of Inflammation, and Microvascular Flap Thrombosis in Reconstructive Surgery

  • Rihards Peteris Rocans,
  • Janis Zarins,
  • Evita Bine,
  • Insana Mahauri and ,
  • Renars Deksnis,
  • Margarita Citovica,
  • Simona Donina,
  • Indulis Vanags,
  • Sabine Gravelsina and
  • Biruta Mamaja
  • + 7 authors+ 2 authors

12 September 2024

Background: Microvascular flap surgery has become a routine option for defect correction. The role of von Willebrand factor antigen (VWF:Ag) in the pathophysiology of flap complications is not fully understood. We aim to investigate the predictive va...

(This article belongs to the Special Issue Microsurgery: Current and Future Perspectives)
  • Article
  • Open Access
3 Citations
1,360 Views
6 Pages

Study Design: Retrospective cohort study. Objective: Malnutrition has been found to have negative effects on the immune system and inflammatory responses, impairing the wound healing process. Free flap failure is a serious complication in patients un...

  • Article
  • Open Access
18 Citations
5,819 Views
14 Pages

A Protocol for the Use of a Combined Microvascular Free Flap with Custom-Made 3D-Printed Total Temporomandibular Joint (TMJ) Prosthesis for Mandible Reconstruction in Children

  • Krzysztof Dowgierd,
  • Rafal Pokrowiecki,
  • Maciej Borowiec,
  • Marcin Kozakiewicz and ,
  • Dominika Smyczek and
  • Łukasz Krakowczyk
  • + 1 author+ 0 author

2 March 2021

Extended postoperative mandibular reconstructions due to orofacial disease involving the temporomandibular joint (TMJ) in immature patients remain a challenge as a result of ongoing growth, which is usually affected by the disease and treatment. Curr...

(This article belongs to the Special Issue Current Challenges of Oral and Maxillofacial Surgery)
  • Article
  • Open Access
131 Views
15 Pages

24 October 2026

Background/Objectives: Conventional interrupted microvascular anastomosis is technically demanding and time-consuming. We developed an intraluminal microtube anastomosis system (IMAS) in which circumferential anchoring ridges on the outer surface mec...

(This article belongs to the Section General Surgery)
  • Article
  • Open Access
1,883 Views
17 Pages

Molecular Genetic Analysis of Perioperative Colonization by Infection-Related Microorganisms in Patients Receiving Intraoral Microvascular Grafts

  • Henriette Louise Moellmann,
  • Katharina Kommer,
  • Nadia Karnatz,
  • Klaus Pfeffer and ,
  • Birgit Henrich and
  • Majeed Rana
  • + 1 author+ 0 author

13 July 2024

Background/Objectives: In oral and maxillofacial surgery, the reconstruction of defects often involves the transfer of skin tissue into the oral cavity utilizing microvascular grafts. This study investigates postoperative changes in microbial coloniz...

(This article belongs to the Special Issue Current Perspectives and Future Directions in Oral and Maxillofacial Surgery)
  • Article
  • Open Access
10 Citations
2,535 Views
14 Pages

Elective Tracheotomy in Patients Receiving Mandibular Reconstructions: Reduced Postoperative Ventilation Time and Lower Incidence of Hospital-Acquired Pneumonia

  • Johannes G. Schuderer,
  • Leonie Reider,
  • Michael Wunschel,
  • Gerrit Spanier and ,
  • Steffen Spoerl,
  • Maximilian Josef Gottsauner,
  • Michael Maurer,
  • Johannes K. Meier,
  • Peter Kummer and
  • Tobias Ettl
  • + 6 authors+ 1 author

22 January 2023

Elective tracheotomy (ET) secures the airway and prevents adverse airway-related events as unplanned secondary tracheotomy (UT), prolonged ventilation (PPV) or nosocomial infection. The primary objective of this study was to identify factors predispo...

(This article belongs to the Special Issue State of the Art in Craniofacial Surgery)
  • Article
  • Open Access
17 Citations
3,578 Views
18 Pages

The Impact of Healthcare-Associated Infections in Patients Undergoing Oncological Microvascular Head and Neck Reconstruction: A Prospective Multicentre Study

  • Ana Ramos-Zayas,
  • Francisco López-Medrano,
  • Irene Urquiza-Fornovi,
  • Ignacio Zubillaga and ,
  • Ramón Gutiérrez,
  • Gregorio Sánchez-Aniceto,
  • Julio Acero,
  • Fernando Almeida,
  • Ana Galdona and
  • José Luis Cebrián
  • + 7 authors+ 2 authors

27 April 2021

(1) Background: Healthcare-associated infections (HAIs) after head and neck free-flap reconstruction are a common postoperative complication. Risk factors for HAIs in this context and their consequences have not been adequately described. (2) Methods...

(This article belongs to the Special Issue Surgical Treatment of Head and Neck Squamous Cell Carcinomas (HNSCC))
  • Article
  • Open Access
663 Views
18 Pages

28 February 2026

Background/Objectives: Locally advanced midface malignant tumors require extensive resection, resulting in complex defects involving bone and multiple soft tissue structures. Reconstructing these substantial defects presents a significant challenge t...

(This article belongs to the Special Issue Innovations in Head and Neck Surgery)
  • Article
  • Open Access
476 Views
14 Pages

Perioperative Anesthetic Factors and Flap Outcome in Pediatric Head and Neck Free Flap Reconstruction: A Retrospective Study

  • Dominika Lech,
  • Robert Maksymowicz,
  • Jeremi Matysek,
  • Cyprian Strączek and ,
  • Michalina Ceroń,
  • Marcin Kozakiewicz,
  • Łukasz Krakowczyk and
  • Krzysztof Dowgierd
  • + 3 authors+ 0 author

3 June 2026

Background: Microvascular free flap reconstruction is an established method for the management of complex head and neck defects in pediatric patients. However, the influence of perioperative anesthetic management on flap outcome in this population re...

(This article belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
  • Article
  • Open Access
22 Citations
6,003 Views
12 Pages

Scalp Reconstruction Using the Latissimus Dorsi Free Flap: A 12-Year Experience

  • Felix Strübing,
  • Fabian Wenz,
  • Nima Etminan,
  • Amir K. Bigdeli and ,
  • Laura C. Siegwart,
  • Benjamin Thomas,
  • Felix Vollbach,
  • Julian Vogelpohl,
  • Ulrich Kneser and
  • Emre Gazyakan
  • + 5 authors+ 0 author

19 April 2023

Background: Complex scalp defects are regularly reconstructed using microvascular tissue transfer. The latissimus dorsi free flap is one of the workhorse flaps used in scalp reconstruction. These cases necessitate, particularly in the elderly, a clos...

(This article belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
  • Article
  • Open Access
7 Citations
3,684 Views
17 Pages

Effects of Pre-Operative Risk Factors on Intensive Care Unit Length of Stay (ICU-LOS) in Major Oral and Maxillofacial Cancer Surgery

  • Juergen Wallner,
  • Michael Schwaiger,
  • Sarah-Jayne Edmondson,
  • Irene Mischak and ,
  • Jan Egger,
  • Matthias Feichtinger,
  • Wolfgang Zemann and
  • Mauro Pau
  • + 3 authors+ 0 author

4 August 2021

Objective: This study aimed to investigate the effect of certain pre-operative parameters directly on the post-operative intensive care unit (ICU)-length of stay (LOS), in order to identify at-risk patients that are expected to need prolonged intensi...

(This article belongs to the Special Issue Head and Neck Cancer Imaging and Image Analysis)
  • Case Report
  • Open Access
1,521 Views
23 Pages

28 October 2025

Background: Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity, often necessitating extensive surgical resection. Such interventions may result in complex intraoral defects requiring immediate reconstruction to resto...

(This article belongs to the Special Issue Dental Oncology)
  • Article
  • Open Access
1 Citations
4,105 Views
10 Pages

Is the Sublingual Artery a Reliable Alternative for Intraoral Anastomoses in Head and Neck Free-Flap Reconstruction? Anatomical Basis and Preliminary Results

  • Vasco Starke,
  • Jürgen Wallner,
  • Robert Stigler,
  • Sidney Mannschatz and ,
  • Jakob Müller and
  • Erich Brenner
  • + 1 author+ 0 author

31 October 2024

Background/Objectives: Head and neck free-flap reconstructions are often required to treat tumors or extensive post-traumatic jaw defects. The facial artery is the standard receiving vessel for intraoral microvascular anastomoses. However, its use is...

(This article belongs to the Section Peripheral Vascular Diseases)
  • Review
  • Open Access
2 Citations
4,916 Views
15 Pages

Use of Thromboelastography and Rotational Thromboelastometry in Otolaryngology: A Narrative Review

  • Mathew K. Marsee,
  • Faisal S. Shariff,
  • Grant Wiarda,
  • Patrick J. Watson and ,
  • Ali H. Sualeh,
  • Toby J. Brenner,
  • Max L. McCoy,
  • Hamid D. Al-Fadhl,
  • Alexander J. Jones and
  • Craig Folsom
  • + 7 authors+ 2 authors

20 February 2022

In the field of otolaryngology—head and neck surgery (ENT), coagulopathies present unique diagnostic and therapeutic challenges. In both hyper- and hypocoagulable patients, management of coagulopathies requires intricate attention to the nature...

(This article belongs to the Special Issue Clinical Research on Viscoelastic Testing)
  • Article
  • Open Access
3 Citations
2,336 Views
14 Pages

The Effect of Preoperative Anemia on Blood Transfusion Outcomes in Major Head and Neck Cancer Surgery

  • Munib Ali,
  • Steven C. Nakoneshny,
  • Joseph C. Dort,
  • Khara M. Sauro and ,
  • Thomas Wayne Matthews,
  • Shamir P. Chandarana,
  • Todd A. Wilson,
  • David C. McKenzie,
  • Christiaan Schrag and
  • Robert D. Hart
  • + 6 authors+ 1 author

25 June 2025

Background/objectives: Major head and neck oncologic surgeries requiring microvascular reconstruction frequently result in complications such as perioperative blood transfusion (PBT). Not only are blood products overutilized and associated with risks...

(This article belongs to the Section Clinical Research in Cancer)
  • Article
  • Open Access
3,323 Views
15 Pages

Metabolic Predictors in Risk Stratification for Oral Cavity and Oropharyngeal Cancer Patients Undergoing Free Flap Tissue Transfer: A Retrospective Study

  • Darko Solter,
  • Andro Koren,
  • Luciana Koren,
  • Emili Dragaš and ,
  • Alan Pegan,
  • Goran Geber,
  • Davor Vagić and
  • Andro Košec
  • + 3 authors+ 0 author

20 February 2026

Background/Objectives: Oral and oropharyngeal cancers are highly prevalent and associated with a high mortality. The primary treatment modality is surgery with free flap reconstruction becoming the gold standard. Our study aimed to assess the anthrop...

(This article belongs to the Special Issue Oral Cancer: The Latest Advances in Clinical and Basic Research (Second Edition))
  • Article
  • Open Access
23 Citations
4,240 Views
12 Pages

16 March 2022

Background: Vascular patency is the key element for high flap survival rates. The purpose of this study was to assess and compare the blood flow characteristics of deep inferior epigastric perforator (DIEP) and muscle-sparing transverse rectus abdomi...

(This article belongs to the Section Methodology, Drug and Device Discovery)
  • Article
  • Open Access
7 Citations
3,825 Views
12 Pages

Osteoradionecrosis of the Jaw—Comparison between Bone and Soft Tissue Injury and Their Influence on Surgical Outcomes—A Retrospective Cohort Study

  • Oliver Ristow,
  • Jan Lukas Birgel,
  • Thomas Rückschloß,
  • Thomas Held and ,
  • Kristin Lang,
  • Maximilian Smielowski,
  • Sven Zittel,
  • Julius Moratin,
  • Maximilian Pilz and
  • Karl Semmelmayer
  • + 7 authors+ 2 authors

Surgical therapy of osteoradionecrosis of the jaw (ORN) is challenging and requires treatment of the affected hard and soft tissue. To understand how tissue injury after irradiation influences surgical outcomes, the objective of this study was to fin...

(This article belongs to the Section Medical Imaging and Theranostics)

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