Leveraging the rapid carrier recovery times and minimal polarization sensitivity of carrier-reservoir semiconductor optical amplifiers (CR-SOAs), this study embeds them in a Mach–Zehnder interferometer (MZI) setup to emulate a 2x1 multiplexer (...
The increasing prevalence of the mobile tigecycline resistance gene tet(X) poses a severe global health threat, and the genus Acinetobacter is a major reservoir. This study aimed to develop a rapid and specific multiplex PCR assay for detecting the p...
Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful technique for investigating biological heterogeneity at the single-cell level in human systems and model organisms. Recent advances in scRNA-seq have enabled the pooling of cells from m...
Diffraction-limited resolution and low penetration depth are fundamental constraints in optical microscopy and in vivo imaging. Recently, liquid-jet X-ray technology has enabled the generation of X-rays with high-power intensities in laboratory setti...
Prostate cancer (PCa) remains one of the most prominent forms of cancer for men. Since the early 1990s, Prostate-Specific Antigen (PSA) has been a commonly recognized PCa-associated protein biomarker. However, PSA testing has been shown to lack in sp...
Bacillus cereus is a spore-forming ubiquitous bacterium notable as a food poisoning agent. Detection of B. cereus spores using selective media is laborious and non-specific. Herein, the quantitative detection of B. cereus spores was investigated with...
In this paper, we analyze the applicability of color-space-based, color-independent visual-MIMO for V2X. We aim to achieve a visual-MIMO scheme that can maintain the original color and brightness while performing seamless communication. We consider t...
African horse sickness is a severe and often fatal disease affecting all species of equids. The aetiological agent, African horse sickness virus (AHSV), can be differentiated into nine serotypes. The identification of AHSV serotypes is vital for dise...
Background/Objectives: The clinically validated multiplex Oncuria bladder cancer (BC) assay quickly and noninvasively identifies disease risk and tracks treatment success by simultaneously profiling 10 protein biomarkers in voided urine samples. Oncu...
To enable highly reliable and spectrum-efficient vehicle-to-everything (V2X) communications under conditions with severe Doppler effects and rapidly time-varying channels, we propose a novel faster-than-Nyquist orthogonal time frequency space (FTN-OT...
All-inorganic lead halide perovskite (CsPbX3) nanocrystals (NCs) have emerged as a highly promising new generation of light emitters due to their extraordinary photophysical properties. However, the performance of these semiconducting NCs is undermin...
An increase in the frequency of mycoses and spreading of multidrug-resistant fungal pathogens necessitates the search for new antifungal agents. Earlier, we isolated the novel defensin from lentil Lensculinaris seeds, designated as Lc-def, which inhi...
This work concentrates on the problem of optimizing the cost of a passive wavelength division multiplexing (WDM) optical network used as a transport network for carrying the xHaul packet traffic between a set of remote radio sites and a central hub i...
Twenty-five years ago, a pathogenic variant of the phosphate-regulating endopeptidase homolog X-linked (PHEX) gene was identified as the cause of X-linked hypophosphatemic rickets (XLH). Subsequently, the overproduction of fibroblast growth factor 23...
Bacterial leaf scorch (BLS), caused by Xylella fastidiosa (Xf), is a prevalent disease of blueberries in the southeastern United States. Initially, this disease was reported to be caused by X. fastidiosa subsp. multiplex (Xfm). However, a recent surv...
We investigate the nanometrology of sub-nanometre particle sizes in industrially manufactured sodium silicate liquors at high pH using time-resolved fluorescence anisotropy. Rather than the previous approach of using a single dye label, we investigat...
Bluetongue is an economically important disease of ruminants caused by the bluetongue virus (BTV). BTV is serologically diverse, which complicates vaccination strategies. Rapid identification of the causative BTV serotypes is critical, however, real-...
Exosome-based vaccines represent a transformative platform in modern vaccinology, combining nanoscale delivery, biocompatibility, and potent immunogenicity. Among these, the StealthX platform developed by Capricor, Inc. has demonstrated exceptional v...
Pediocin-like bacteriocins are among the natural antimicrobial agents attracting attention as scaffolds for the development of a new generation of antibiotics. Acidocin A has significant structural differences from most other members of this subclass...
Orbital angular momentum (OAM) multiplexing of electromagnetic (EM) waves is of great significance for high-speed wireless communication and remote sensing. To achieve high-efficiency OAM multiplexing for multi-channel incident EM waves, this paper p...
19 December 2022
Early diagnosis of drug susceptibility for tuberculosis (TB) patients could guide the timely initiation of effective treatment. We evaluated a novel multiplex xMAP TIER (Tuberculosis-Isoniazid-Ethambutol-Rifampicin) assay based on the Luminex xMAP sy...
Multiplex lateral flow immunoassay (LFIA) is largely used for point-of-care testing to detect different pathogens or biomarkers in a single device. The increasing demand for multitargeting diagnostics requires multi-informative single tests. In this...
One of the main challenges in dense 5G radio access networks (RANs) is provisioning of low-cost connectivity between a large number of antennas, located at remote sites, and a central site (hub) in which baseband processing functions are performed. P...
Current hemostatic agents are obtained from pooled plasma from multiple donors requiring costly pathogen screening and processing. Recombinant DNA-based production represents an engineering solution that could improve supply, uniformity, and safety....
The emission of nanoscale particles from the surfaces of dental implants leads to the cumulative effect of particle complexes in the bone bed and surrounding soft tissues. Aspects of particle migration with the possibility of their involvement in the...
The polarization multiplexing technique is a well-established method that improves the communication capacity of an optical system. In this paper, we designed orthogonal linear and circular polarization multiplexing metalens using a library of rectan...
Background: The genetic quality of laboratory mice may have a direct impact on the results of research. Therefore, it is essential to improve genetic monitoring methods to guarantee research quality. However, few current methods boast high efficiency...
Microfluidic paper-based analytical devices (µPADs) are ideal for point-of-care diagnostics due to their low cost, compact size, and ease of use. However, current designs have limited multiplexing capabilities, making it difficult to simultaneo...
Backgroud/Objectives: Canine Visceral Leishmaniasis (CVL), caused by Leishmania infantum, is a significant public health concern due to dogs serving as reservoirs for human infection. An accurate and rapid diagnostic method to distinguish symptomatic...
In newborn screening (NBS), it is important to consider the availability of multiplex assays or other tests that can be integrated into existing systems when attempting to implement NBS for new target diseases. Recent developments in innovative testi...
Microbial detection in milk is crucial for food safety and quality, as beneficial and harmful microorganisms can affect consumer health and dairy product integrity. Identifying and quantifying these microorganisms helps prevent contamination and spoi...
Hepatitis B virus (HBV) chronically infects more than 240 million people worldwide, causing chronic hepatitis, cirrhosis, and hepatocellular carcinoma (HCC). Genome editing using CRISPR/Cas9 could provide new therapies because it can directly disrupt...
The need for a high-speed transmission network has become essential due to the exponential increase in traffic. In this paper, a free-space-optics (FSO) link modelled by integrating two multiplexing techniques, i.e., spectral amplitude coding-optical...
Optical twin-single sideband (Twin-SSB) modulation, due to the left sideband (LSB) and right sideband (RSB) signal carrying individual data, has become an attractive technique in fiber transmission because it satisfies the demand of the explosive inc...
(1) Background: Atopic dermatitis constitutes one of the most common inflammatory skin manifestations of the pediatric population. The onset of many inborn errors occurs early in life with an AD–like picture associated with a deregulated IgE re...
Polarization is one of the physical characteristics of optical waves, and the polarization-division-multiplexing (PDM) scheme has gained much attraction thanks to its capability of achieving high transmission rate. In the PDM-based quantum key distri...
The vector control method is applied to a whole angle hemispherical resonator gyroscope (HRG). The detection and control of the resonator vibration state are implemented using orthogonal X/Y channels. However, the performance of the HRG is limited by...
The V2X environment poses many challenges to emerging wireless communication systems, while it is crucial to ensure the efficiency and safety of road users. Requiring continual localization of the surroundings and accurate obstacle detection while pr...
With the increase in user density, it is a challenging problem to achieve higher energy efficiency in vehicle-to-everything (V2X) networks, where frequent handovers occur as users continuously pass through dense cell boundaries. In this paper, we inv...
Sixth-generation mobile communication (6G) aims to further improve capacity and reliability by controlling the radio propagation environment. Millimeter wave (mmWave) high-frequency band communication offers large bandwidth at the cost of high attenu...
Colistin resistance poses a significant clinical challenge, particularly in Gram-negative bacteria. This study investigates the occurrence of plasmid-mediated colistin resistance among Enterobacterales isolates (Escherichia coli, Klebsiella pneumonia...
CAH-X is a hypermobility-type Ehlers–Danlos syndrome connective tissue dysplasia affecting approximately 15% of patients with 21-hydroxylase deficiency (21-OHD) congenital adrenal hyperplasia (CAH) due to contiguous deletion of CYP21A2 and TNXB...
21-hydroxylase deficiency (21OHD), the most common form of congenital adrenal hyperplasia (CAH), is associated with pathogenic variants in CYP21A2 gene. The clinical form of the disease ranges from classic or severe to non-classic (NC) or mild late o...
A multi-function microelectromechanical system (MEMS) with a three-axis magnetometer (MAG) and three-axis accelerometer (ACC) function was implemented with an application-specific integrated circuit (ASIC)-compatible complementary metal-oxide-semicon...
The genome composition of intermediate wheatgrass (IWG; Thinopyrum intermedium (Host) Barkworth and D.R. Dewey; 2n = 6x = 42) is complex and remains to be a subject of ongoing investigation. This study employed fluorescence in situ hybridization (FIS...
For many genetic disorders, there are no specific metabolic biomarkers nor analytical methods suitable for newborn population screening, even where highly effective preemptive treatments are available. The direct measurement of signature peptides as...
Based on the Fourier transform (FT) of surface plasmon polaritons (SPPs), the relation between the displacement of the plasmonic field and the spatial frequency of the excitation light is theoretically established. The SPPs’ field shifts transv...
Duchenne and Becker muscular dystrophies, caused by pathogenic variants in DMD, are the most common inherited neuromuscular conditions in childhood. These diseases follow an X-linked recessive inheritance pattern, and mainly males are affected. The m...
Thermal ablation is achieved by delivering heat directly to tissue through a minimally invasive applicator. The therapy requires a temperature control between 50–100 °C since the mortality of the tumor is directly connected with the thermal...
Low Density Signature (LDS) is an emerging non-orthogonal multiple access (NOMA) technique that has never been evaluated under a vehicular channel in order to simulate the environment of a vehicle to everything (V2X) communication. Moreover, the LDS...
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