Special Issues

Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Redox Regulation in Cardiovascular Diseases submission deadline 31 Dec 2025 | 3 articles | Viewed by 7928 | Submission Open
Keywords: oxidative stress; mitochondria; metabolism; chronic inflammation; atherosclerosis; CVD; ROS
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Therapies in Cardiovascular, Cardiorenal and Metabolic Diseases
edited by Kaushik P. Patel, Hong Zheng and
submission deadline 31 Dec 2025 | 5 articles | Viewed by 6497 | Submission Open
Keywords: antioxidant therapies; oxidative stress; cardiovascular diseases; cardiorenal diseases; metabolic diseases
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and Male Reproductive Health submission deadline 31 Dec 2025 | 6 articles | Viewed by 6437 | Submission Open
Keywords: oxidative stress; antioxidant therapy; male reproductive health; male fertility; erectile dysfunction; prostatic disease; male ageing
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Multi-Target Profile of Antioxidant Compounds, Including Repurposing and Combination Strategies—2nd Edition
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 4259 | Submission Open
Keywords: polypharmacology; multi-target ligands; rational drug; design repurposing; off-target effects; computational techniques
Natural Antioxidants in Pharmaceuticals and Dermatocosmetology
edited by
submission deadline 31 Dec 2025 | 4 articles | Viewed by 4210 | Submission Open
Keywords: phytochemicals; antioxidant; pharmaceuticals; dermatocosmetic products; in vitro and in vivo evaluations; clinical trials
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Activity of Polyphenolic Extracts
edited by
submission deadline 31 Dec 2025 | 3 articles | Viewed by 3724 | Submission Open
Keywords: antioxidant activity; polyphenols; plant extracts; oxidative stress
Agri-Food Wastes as Natural Source of Bioactive Antioxidants: Fourth Edition submission deadline 31 Dec 2025 | 3 articles | Viewed by 3562 | Submission Open
Keywords: agri-food by-products; agri-food waste; nutraceuticals; functional foods; cosmeceutical products; sustainable practices; bioactive compounds; health effects
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Oxidative Stress in Rare Diseases: Mechanisms, Implications, and Therapeutic Opportunities submission deadline 31 Dec 2025 | 2 articles | Viewed by 3203 | Submission Open
Keywords: rare diseases; oxidative stress; free radicals; biomedicine; redox biomarkers; redox epigenetics; redox metabolism; redox control of protein function; ferroptosis
Role of Reactive Oxygen Species (ROS) in Tumor Microenvironment Modulation submission deadline 31 Dec 2025 | 2 articles | Viewed by 2743 | Submission Open
Keywords: reactive oxygen species; tumor microenvironment; stroma cells; functional genomics; spatial transcriptomics; single-cell sequencing; RNA-seq; cancer; diagnosis and prognosis; biomarkers
Natural Antioxidants in Animal Nutrition
edited by , , Chao Wang, Hao Zhang and Jingfei Zhang
submission deadline 31 Dec 2025 | 2 articles | Viewed by 2668 | Submission Open
Keywords: antioxidants; animal; growth; metabolism; nutrition; oxidative stress; plant extracts
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress, Antioxidants, and Mechanisms in FLASH Radiotherapy submission deadline 31 Dec 2025 | 2 articles | Viewed by 2512 | Submission Open
Keywords: radiobiology and radiotherapy; ultra-high dose rate irradiation and the FLASH effect; molecular and cellular mechanisms; radiation-induced oxidative stress; reactive oxygen and nitrogen species; inflammatory processes; antioxidants and radioprotectors; pulse radiolysis; kinetics; physicochemical and biological processes; DNA damage; role of oxygen and the oxygen depletion hypothesis; modeling and experimental; FLASH particle therapy
Carotenoids in Health and Disease
edited by Kazutoshi Shindo
submission deadline 31 Dec 2025 | 2 articles | Viewed by 2365 | Submission Open
Keywords: antioxidant activities of carotenoids; analytical chemistry on carotenoids; reactive oxygen species (ROS) and disease; production of carotenoids
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Selected Papers from the 2nd International Electronic Conference on Antioxidants (IECAN2025) submission deadline 31 Dec 2025 | 1 articles | Viewed by 1680 | Submission Open
Keywords: obesity; cardiovascular diseases; chronic disease; dietary prevention; antioxidants intake; gut microbiome; natural and synthetic antioxidants; antioxidant enzyme systems; antioxidant extraction
Redox Biology and Genomic Integrity
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1521 | Submission Open
Keywords: redox biology; reactive oxygen species (ROS); oxidative stress; oxidative DNA damage; genome stability; DNA repair; hypermutation; antioxidant defense mechanisms; mitochondrial dysfunction; Saccharomyces cerevisiae; cellular adaptation; epigenetics; telomeres
From Field to Cell: Redox Mechanisms of Chemical Stressor Toxicity in Biological Systems submission deadline 31 Dec 2025 | Viewed by 1096 | Submission Open
Keywords: redox biology; environmental toxicology; chemical stressors; pesticides; redox signaling
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress in Respiratory Disorders
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 935 | Submission Open
Keywords: oxidative stress; lung; reactive oxygen species; reactive nitrogen species; acute lung injury; asthma; COPD; lung fibrosis; pulmonary silicosis; premature neonate
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Metabolic Dysfunction and Oxidative Stress submission deadline 31 Dec 2025 | 1 articles | Viewed by 742 | Submission Open
Keywords: iron; mitochondria; oxidative stress; inflammation; metabolism; free radicals
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Super Oxide Dismutase (SOD) Isoenzymes and Reactive Oxygen Species (ROS) in Immuno-Pathophysiology
edited by Giuseppina Ruggiero and
submission deadline 31 Dec 2025 | 1 articles | Viewed by 348 | Submission Open
Keywords: superoxide dismutase (SOD) isoenzymes; superoxide dismutase (SOD)1; cell signalling; cell metabolism; cell functions; cellular stress; disease pathogenesis
Modulation of Biochemical, Cellular and Physiological Mechanisms in Response to Oxidative Stress in Animals submission deadline 31 Dec 2025 | Viewed by 326 | Submission Open
Keywords: animals; cell signaling; metabolism; cell death responses; oxidative damage
Antioxidant Properties of Functional Foods
edited by Konstantinos G. Adamopoulos and
submission deadline 31 Dec 2025 | Viewed by 310 | Submission Open
Keywords: antioxidant; extraction; bioavailability; processing; optimization; functional food; phytochemicals
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Phenolic Antioxidants in Functional Foods and Nutraceuticals submission deadline 31 Dec 2025 | Viewed by 298 | Submission Open
Keywords: bioactive compounds; agri-food byproducts; in vitro assays; in vivo studies; green extraction; biological activities; safety assessment; industrial application
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Sustainable Food, Green Chemistry and Human Nutrition (GreenNutriFood 2025)
edited by , , and Andrea Asensio-Grau
submission deadline 31 Dec 2025 | Viewed by 283 | Submission Open
Keywords: food; nutrition; food processing; food packaging; green chemistry; meat; food waste; by-products; functional foods; fermentation; biofortification; food additives; food safety; shelf life; gut microbiome; seafood; marine resources
Emerging Trends in Antioxidant Nutraceuticals submission deadline 31 Dec 2025 | Viewed by 277 | Submission Open
Keywords: nutraceuticals; diabetes; cancer; oxidative stress; inflammation; antioxidant
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Development and Application of Detection Methods for Reactive Oxygen Species and Antioxidants submission deadline 31 Dec 2025 | Viewed by 213 | Submission Open
Keywords: antioxidant extraction; antioxidant assay; sensors for reactive oxygen species (ROS); ROS scavenger assays; biological samples; oxidative stress status; nutritional value; food analysis; bioassays; enzymatic assays; redox cycle; cell imaging
(This special issue belongs to the Section Methods for Antioxidants Evaluation/Measurement)
Metabolism and Epigenetics: A Potential Dual Interaction in the Microenvironment of Solid Tumors
edited by , , and Sebastiano Giallongo
submission deadline 31 Dec 2025 | Viewed by 213 | Submission Open
Keywords: metabolomics; tumor cell metabolism; tumor microenvironment; cell communication; cell signaling; epigenetics; post-translational modifications; cancer therapy
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Radiation Exposure and Health: The Role of Oxidative Stress and Inflammatory Response submission deadline 31 Dec 2025 | Viewed by 123 | Submission Open
Keywords: radiation; inflammatory response; oxidative stress
Natural Antioxidants in Functional Foods
edited by , Palmira De Bellis and
submission deadline 31 Dec 2025 | Viewed by 118 | Submission Open
Keywords: polyphenols; functional foods; fermentation; antioxidant activity; anti-inflammatory activity
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
The Role of Dietary Antioxidants in Alleviating Oxidative Stress and Inflammation for Enhanced Immunity in Animals
edited by Yanka D. Karamalakova and
submission deadline 31 Dec 2025 | Viewed by 98 | Submission Open
Keywords: antioxidants; antioxidant feeding; insect meal; growth performance; digestible energy; nutrient digestibility; blood biochemistry; oxidative stress (OS); lipid peroxidation (MDA); ROS/RNS; superoxide dismutase (SOD); catalase (CAT); glutathione (GSH); glutathione peroxidase (GPx); inflammation markers; total antioxidant capacity (TAC); meat; milk; eggs quality
Studies on Antioxidants and Anti-Aging Substances Using Model Organisms and Cell Cultures
edited by
submission deadline 31 Dec 2025 | Viewed by 96 | Submission Open
Keywords: antioxidants; anti-aging substances and natural products; experimental animals; 3D cell culture models; organoids; acting mechanisms; antioxidant genes; autophagy; proteasome
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Research in Chile—2nd Edition submission deadline 31 Dec 2025 | Viewed by 91 | Submission Open
Keywords: antioxidants; biotechnology; biomedicine; natural products; nutrition; oxidative stress; Chilean plants of economic importance; polyphenols; flavonoids; anthocyanins; phenolic acids; resveratrol; food waste; plant extracts; neuroinflammation; redox signaling; circular economy; ROS scavengers; antioxidants in industry; entrepreneurship; green startups
Editorial Board Members’ Collection Series: Advances in Redox-Tools and Therapies in Cardiovascular Disease submission deadline 31 Dec 2025 | Viewed by 88 | Submission Open
Keywords: cardiovascular disease; oxidative stress; inflammation; reactive oxygen species; redox signalling
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Novel Strategies for Oxidative Stress Management: Dietary Interventions for Liver and Gut Health
edited by and
submission deadline 31 Dec 2025 | Viewed by 82 | Submission Open
Keywords: antioxidant compounds; phytochemicals; dietary interventions; hepatic disease; intestinal disease; redox homeostasis
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress, Mitochondrial Dysfunction, and Inflammation in Autism
edited by
submission deadline 31 Dec 2025 | Viewed by 66 | Submission Open
Keywords: autism; oxidative stress; mitochondria; inflammation; redox signaling; antioxidants; reactive oxygen species; immune response
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Bioavailability of Antioxidants: From Omics Insights to Health Outcomes submission deadline 31 Dec 2025 | Viewed by 62 | Submission Open
Keywords: bioavailability; nutrigenomics; metabolomics; gut microbiota; dietary polyphenols; functional foods; biotransformation; systems biology; antioxidants; bioactivity
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidants and Dietary Nutrition: Emerging Trends, and Clinical Applications submission deadline 31 Dec 2025 | Viewed by 61 | Submission Open
Keywords: antioxidants; oxidative stress; chronic disease prevention; dietary strategies; bioavailability
Antioxidant Natural Products and Peptides in Cosmetics submission deadline 31 Dec 2025 | Viewed by 55 | Submission Open
Keywords: cosmetics; herbal extracts; natural products; peptides; synthesis; isolation; oxidative stress; emulsions; nanoparticles; fibroblasts; ageing
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Sustainable Strategies for Natural Antioxidant Utilization
edited by and Atalanti Christou
submission deadline 31 Dec 2025 | Viewed by 52 | Submission Open
Keywords: extraction; antioxidants; polyphenols; phytochemicals; green chemistry; sustainable process; natural products; drug discovery; formulation; natural product analysis
Oxidative Stress and Mitochondrial Dysfunction in Metabolic Disorders
edited by , and Hugo J Alves-Figueiredo
submission deadline 31 Dec 2025 | Viewed by 50 | Submission Open
Keywords: metabolic diseases; oxidative stress; mitochondrial dysfunction; antioxidant therapies; lifestyle interventions; gene therapies; mitochondrial transfer therapies
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Algal Antioxidants: Physiology, Metabolism, and Evolution
edited by
submission deadline 31 Dec 2025 | Viewed by 48 | Submission Open
Keywords: algae; antioxidant; oxidative stresses; algal physiology
Antioxidants for Skin Health—2nd Edition
edited by Rubia Casagrande
submission deadline 31 Dec 2025 | Viewed by 47 | Submission Open
Keywords: skin inflammation; cytokine; skin oxidative stress; Nrf2; reduced glutathione; ultraviolet irradiation; drug delivery; flavonoid; terpenes; specialized pro-resolution lipid mediators
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Hydrogen Sulfide and Its Role in Inflammatory and Degenerative Joint Diseases
edited by Guenter Steiner and Burkhard Klösch
submission deadline 31 Dec 2025 | Viewed by 28 | Submission Open
Keywords: hydrogen sulfide; inflammation; antioxidant; osteoarthritis; rheumatoid arthritis; degeneration; chondrocyte; monocyte; fibroblast; drug development
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and Adaptive Responses in Space Medicine and Physiology
edited by
submission deadline 31 Dec 2025 | Viewed by 27 | Submission Open
Keywords: antioxidant defense  ; microgravity  ; oxidative stress  ; radiation  ; space medicine  ; space physiology
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Redox Regulation of Plant Growth and Development
edited by Judit Dobránszki and
submission deadline 31 Dec 2025 | Viewed by 24 | Submission Open
Keywords: plant biology; ascorbate; free-radical scavenging; glutathione; heat shock proteins; melatonin; oxidative stress; plant growth and development; redox homeostasis; RNP; ROS; plant stress mitigation; plant stress adaptation; transcription factors
(This special issue belongs to the Section ROS, RNS and RSS)
Biomarkers of Oxidative Stress in Lung Disease
edited by
submission deadline 31 Dec 2025 | Viewed by 10 | Submission Open
Keywords: oxidative stress; reactive oxygen species; reactive nitrogen species; antioxidants; lung inflammation; bronchial inflammation; COPD; asthma; lung fibrosis; mitochondria
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Phytochemicals for Promoting Human Health and Well-Being submission deadline 10 Jan 2026 | Viewed by 192 | Submission Open
Keywords: antioxidant phytochemicals; oxidative stress; health promotion; chronic disease; functional foods; nutraceuticals
Antioxidant Effects of Natural Compounds on Cell Metabolism
edited by Ester Tellone and Annamaria Russo
submission deadline 12 Jan 2026 | 2 articles | Viewed by 1477 | Submission Open
Keywords: antioxidants; metabolic pathways; dietary intake; blood cells; bioactive compounds
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Mitochondrial Oxidative Stress in Aging and Disease—2nd Edition submission deadline 15 Jan 2026 | 6 articles | Viewed by 11215 | Submission Open
Keywords: mitochondrial oxidative stress in aging; mitochondrial oxidative stress in age-related or metabolic diseases; mitochondrial signaling via ROS in diseases; mitochondrial oxidative stress and genomic instability; mitochondrial oxidative stress and inflammation; antioxidants as novel therapeutic approaches; mitochondrial pathologies; aging; mitochondrial
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Systems in Plants
edited by , Ilda Jesús Casimiro Felicio and
submission deadline 20 Jan 2026 | 1 articles | Viewed by 710 | Submission Open
Keywords: enzymatic antioxidants; non-enzymatic antioxidants; nitro-oxidative stress; reactive oxygen species; reactive nitrogen species; ROS and RNS signaling
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Exploring the Role of Polyphenols in Oxidative Stress and Cellular Protection submission deadline 20 Jan 2026 | Viewed by 271 | Submission Open
Keywords: polyphenol; oxidative stress; cellular signaling; metabolic pathways
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Advances in Peroxiredoxin Biology
edited by Mikael Molin and Cecilia Picazo
submission deadline 23 Jan 2026 | Viewed by 13 | Submission Open
Keywords: oxidative stress; aging; age-related diseases; H2O2 signaling; redox regulation
(This special issue belongs to the Section Antioxidant Enzyme Systems)
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