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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Oxidative Stress and Antioxidants in Carcinogenesis: A Multifaceted Approach—2nd Edition

edited by

Fábio Rodrigues Ferreira Seiva

submission deadline 31 Mar 2026 | 1 articles | Viewed by 327 | Submission Open

Keywords: oxidative stress; carcinogenesis; reactive oxygen species (ROS); antioxidants; cancer therapeutics

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Therapies, Mitochondrial Function, and Transplantation Strategies: Mechanisms and Emerging Therapeutics

edited by

Junhwan Kim

and

P. Singh

submission deadline 31 Mar 2026 | Viewed by 259 | Submission Open

Keywords: oxidative stress; antioxidant therapies; mitochondrial function; mitochondrial dysfunction

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Peroxiredoxins

edited by

Dong-Seok Lee

submission deadline 31 Mar 2026 | Viewed by 235 | Submission Open

Keywords: peroxiredoxins; oxidative stress; neuron; neuroinflammation; stemness; cancer

(This special issue belongs to the Section Antioxidant Enzyme Systems)

Optimizing Physical Exercise: Post-Exercise Recovery, Oxidative and Nitrosative Stress, and the Role of Physical Activity in Healthy Aging and Neuroprotection

edited by

Celestyna Mila-Kierzenkowska

and

Marta Pawlowska

submission deadline 31 Mar 2026 | Viewed by 220 | Submission Open

Keywords: oxidative stress; exercise; nitrosative stress; post-exercise damage; post-exercise regeneration; aging; neuroprotection

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Therapeutic Potential of Natural Antioxidants in Respiratory Diseases and Airway Inflammation

edited by Yo-Han Han

submission deadline 31 Mar 2026 | Viewed by 163 | Submission Open

Keywords: natural product; acute/chronic lung injury; inflammation; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Redox Signaling in Kidney Diseases

edited by Xiaofeng Yang

submission deadline 31 Mar 2026 | Viewed by 139 | Submission Open

Keywords: oxidative stress; redox signaling; kidney diseases; antioxidant defense; inflammation; biomarkers

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox-Based Targeting of Signaling Pathways as a Therapeutic Approach

edited by

Seung-rock Lee

and Dhiraj Kumar Sah

submission deadline 31 Mar 2026 | Viewed by 117 | Submission Open

Keywords: cellular signaling; redox-based; therapeutic intervention; human disease; longevity

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Roles of Oxidative Stress in Human Pathophysiology

edited by

Alexandros Georgakilas

submission deadline 31 Mar 2026 | Viewed by 112 | Submission Open

Keywords: oxidative stress; reactive oxygen species; redox signaling; antioxidants; inflammation; biomarkers; human diseases; therapy; pathology; pathophysiology

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants in Food Matrices: From Analytical Advances to Circular and Sustainable Applications

edited by

Sara Jaramillo-Carmona

and

Rafael Guillén Bejarano

submission deadline 31 Mar 2026 | Viewed by 106 | Submission Open

Keywords: food matrix; bioaccesibility; bioavailability; functionality; by-products; valorization; circular economy

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Antioxidants and Oxidative Stress at the Crossroads of Autophagy and Ferroptosis

edited by

Elzbieta Janda

and Flavia Biamonte

submission deadline 31 Mar 2026 | Viewed by 97 | Submission Open

Keywords: antioxidants; oxidative stress; ferroptosis; autophagy; molecular mechanisms

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

NMR Spectroscopy for the Characterization of Foods: Applications in Antioxidant Research and Beyond

edited by

Giacomo Di Matteo

and

Federico Brigante

submission deadline 31 Mar 2026 | Viewed by 87 | Submission Open

Keywords: NMR spectroscopy; antioxidants; food science; bioactive compounds; oxidative stability; metabolomics; food processing; health promotion

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Antioxidant and Antidiabetic Activities of Plant Matrices: Methods, Mechanisms, and Translational Relevance

edited by

Sabina Lachowicz-Wiśniewska

submission deadline 31 Mar 2026 | Viewed by 82 | Submission Open

Keywords: antioxidant assays; antidiabetic activity; α -glucosidase; α -amylase; DPP-IV; antiglycation/AGEs; tea (Camellia sinensis); wild plants; neglected and underutilized species (NUS); stachys; root and tuber crops; ultrasound; microwave; bioavailability; metabolomics; layer-by-layer; hydrogels; alginate; pectin; chitosan; zein; processing by-products

Biological Activities of Antioxidant Selenoproteins

edited by

Raquel Martin-Venegas

submission deadline 31 Mar 2026 | Viewed by 81 | Submission Open

Keywords: selenoproteins; selenium metabolism; microbial redox regulation; bacteria– host redox interactions; oxidative stress; antioxidant defence

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Natural Antioxidants from Agro-Wastes and Food Waste: Characterization and Applications

edited by

Charles Manful

and Raymond H. Thomas

submission deadline 31 Mar 2026 | Viewed by 78 | Submission Open

Keywords: natural antioxidants; oxidative stress; carotenoids; terpenes; phytochemicals; polyphenols; functional foods; bioavailability; translational research; chronic diseases; optimization

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Antioxidant Capacity of Natural Products—3rd Edition

edited by

Younghwa Kim

submission deadline 31 Mar 2026 | Viewed by 71 | Submission Open

Keywords: natural antioxidants; oxidative stress; phytochemicals; bioactive compounds; reactive oxygen species (ROS)

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Antioxidant Defenses and Inflammation in Diabetic Retinopathy

edited by Devy Deliyanti

submission deadline 31 Mar 2026 | Viewed by 69 | Submission Open

Keywords: retinal injury; diabetic retinopathy; retinal inflammation; cell death; antioxidant; pro-oxidants; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Dietary, Environmental, and Lifestyle Modulators of Oxidative Stress in Health and Disease

edited by

Ines Drenjančević

and

Ivana Jukić

submission deadline 31 Mar 2026 | Viewed by 58 | Submission Open

Keywords: oxidative stress; nutrition; antioxidants; functional foods; dietary supplements; nutritional interventions; disease prevention; diet and health; environmental

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Biology of Glyoxalases and Advanced Glycation End Products in Health and Diseases

edited by

Cinzia Antognelli

Marilena Pariano

and

Vincenzo Nicola Talesa

submission deadline 10 Apr 2026 | 6 articles | Viewed by 6496 | Submission Open

Keywords: glyoxalases; methylglyoxal; advanced glycation end products; aging; diseases; antioxidants; apoptosis; cell proliferation; nutraceuticals; oxidative stress; inflammation; apoptosis; EMT; cell proliferation; signal transduction; biological mechanisms

(This special issue belongs to the Section Antioxidant Enzyme Systems)

Reactive Nitrogen Species (RNS) and Redox Signaling in Tumors

edited by Maria Clara Franco and

Luciana Hannibal

submission deadline 10 Apr 2026 | 1 articles | Viewed by 6443 | Submission Open

Keywords: tumor biology; reactive nitrogen species; redox signaling; oxidative stress; ROS

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Natural Antioxidants and Metabolic Diseases, 2nd Edition

edited by

José Ángel Rufián-Henares

Fortuna Iannuzzo

Elisabetta Schiano

and

Maria Maisto

submission deadline 10 Apr 2026 | 1 articles | Viewed by 907 | Submission Open

Keywords: metabolic syndrome; antioxidant compounds; diabetes; obesity; cardiovascular diseases; biological effects; food sources; medicinal plants; oxidative stress; inflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Natural Antioxidants for Cosmetic Applications

edited by

Rita Cortesi

and

Maddalena Sguizzato

submission deadline 10 Apr 2026 | 1 articles | Viewed by 889 | Submission Open

Keywords: cosmetic formulations; skin care; oxidative stress; photoprotection

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Synthetic Compounds: Antioxidant and Anti-Inflammatory Activities, Biomedical Properties and Formulations

edited by

Simone Carradori

and

Ilaria D'Agostino

submission deadline 20 Apr 2026 | 3 articles | Viewed by 7216 | Submission Open

Keywords: antioxidants; inflammation pathways; therapeutic activity; redox potential; synthesis; preclinical studies; macrophages; immunomodulation; packaging; formulations; topical application; polymers; nanotechnology; cytotoxicity; mechanism of action; food; drug design

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Novel Antioxidant Mechanisms for Health and Diseases, 2nd Edition

edited by Yoshihisa Koyama

submission deadline 20 Apr 2026 | 3 articles | Viewed by 4274 | Submission Open

Keywords: antioxidant therapy; reactive oxygen species; oxidative stress; nano-antioxidant therapy; nutrigenomics; microbiome

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Targeting Oxidative Stress in Ischemia/Reperfusion Injury

edited by Kenneth J. Dery

submission deadline 20 Apr 2026 | 1 articles | Viewed by 845 | Submission Open

Keywords: ischemia/reperfusion injury; reactive oxygen species; redox-regulated molecular and cellular mechanism; antioxidant-based therapeutic strategies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress, Mitochondrial Dysfunction, and Inflammation in Autism

edited by

Abha Chauhan

submission deadline 20 Apr 2026 | Viewed by 244 | Submission Open

Keywords: autism; oxidative stress; mitochondria; inflammation; redox signaling; antioxidants; reactive oxygen species; immune response

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Lysosomal Function in Health and Disease

edited by

Silvana M. Zanlungo

and Alejandra R. Álvarez

submission deadline 30 Apr 2026 | 3 articles | Viewed by 11868 | Submission Open

Keywords: lysosome; lysosomal dysfunction; lysosome homeostasis; autophagy; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Activities of Phytochemicals in Fruits and Vegetables

edited by

Wen Qin

submission deadline 30 Apr 2026 | 3 articles | Viewed by 6256 | Submission Open

Keywords: ROS and oxidative stress; green and efficient extraction technology of phytochemicals; antioxidant activity of phytochemicals in fruits and vegetables; polyphenols and polysaccharides in fruits and vegetables; phytochemicals and inflammation

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Redox Signaling in Brain Aging and Neurodegeneration

edited by Marco Bisaglia

submission deadline 30 Apr 2026 | 2 articles | Viewed by 3086 | Submission Open

Keywords: aging; autophagy; brain; Alzheimer disease; amyotrophic lateral sclerosis; Friedreich ataxia; Huntington disease; neurodegeneration; oxidative stress; protein aggregation; Parkinson’ s disease; reactive oxygen species

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Resilience Signaling of Functional Nutrients and Neurotoxicant Pollutants for Human Health

edited by

Maria Scuto

and

Angela Trovato Salinaro

submission deadline 30 Apr 2026 | 2 articles | Viewed by 3004 | Submission Open

Keywords: dietary nutrients; polyphenol-basaed nanoparticles; oxidative stress; apoptosis; ferroptosis; pyroptosis; hormesis; inflammation; human health; toxicant pollutants; apoptosis; cancer; nervous system disorders; personalized nutritional therapy

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress from Environmental Exposures

edited by

Giulia Squillacioti

Valeria Bellisario

and

Federica Ghelli

submission deadline 30 Apr 2026 | 2 articles | Viewed by 2657 | Submission Open

Keywords: environmental exposures; human health; air pollution; lifestyle; oxidative stress; particulate matter; environmental stressors

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Striated Muscle and Other Tissues

edited by

Enrique Jaimovich

submission deadline 30 Apr 2026 | 2 articles | Viewed by 2548 | Submission Open

Keywords: ROS/RNS production; mitochondria ROS; NADPH oxidase; metabolic regulation; cardiac oxidative stress; ROS sources; exercise-induced ROS/RNS; antioxidants; ROS/RNS in disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

High-Fat Diet-Induced Oxidative Stress

edited by

María Teresa Llinas Más

and

Isabel Hernández

submission deadline 30 Apr 2026 | 1 articles | Viewed by 2065 | Submission Open

Keywords: saturated fats; fats; high-fat diet; obesity; cardiovascular disease; non-alcoholic fatty liver disease; oxidative stress; antioxidants; cancer; neurodegenerative diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants in Cardiovascular Medicine: Emerging Trends and Future Perspectives

edited by

Matteo Becatti

and

Claudia Fiorillo

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1437 | Submission Open

Keywords: cardiovascular disease; CVD; atherosclerosis; hypertension; heart failure; ischemic heart disease; vascular aging; myocardial remodeling

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Nrf2 and Cardiovascular Function, Diseases, and Therapeutic Targets

edited by

Gao Lie

and

Irving H. Zucker

submission deadline 30 Apr 2026 | 1 articles | Viewed by 906 | Submission Open

Keywords: nuclear factor erythroid 2-related factor 2 (Nrf2); Nrf2-targeted therapies; cardiovascular diseases; antioxidant; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Based on Antioxidant Capacity: The Multifunctional Roles of Bioactive Compounds from Fruits and Vegetables in Precision Nutrition

edited by

Mauro Lombardo

submission deadline 30 Apr 2026 | 1 articles | Viewed by 830 | Submission Open

Keywords: fruits and vegetables; antioxidants; anti-inflammatory; plant compounds; health

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

NRF2 in Non-Communicable Diseases

edited by

Isabel Lastres-Becker

submission deadline 30 Apr 2026 | Viewed by 494 | Submission Open

Keywords: NRF2; oxidative stress; inflammation; proteostasis; mitochondria; redox homeostasis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Innovative Approaches to Antioxidant Activity and Polyphenol Extraction

edited by José Ricardo Pérez-Correa and

María Salomé Mariotti-Celis

submission deadline 30 Apr 2026 | Viewed by 490 | Submission Open

Keywords: polyphenols; novel antioxidant activity methods; sustainable separation technologies; innovative application techniques

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Oxidative Stress in Respiratory Diseases—Second Edition

edited by

Sabina Galiniak

and

Stephen M. Black

submission deadline 30 Apr 2026 | Viewed by 305 | Submission Open

Keywords: reactive oxygen species; inflammation; antioxidant therapy; chronic obstructive pulmonary disease; asthma; cystic fibrosis; nitrosative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Skin Disorders: Therapeutic Potential of Antioxidants

edited by

Hideya Ando

submission deadline 30 Apr 2026 | Viewed by 277 | Submission Open

Keywords: ultraviolet radiation; reactive oxygen species; oxidative stress; skin disorders; skin aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Activity of Natural Bioactive Compounds in Food and Agricultural Byproducts

edited by

Fabiana Pizzolongo

and

Filosa Stefania

submission deadline 30 Apr 2026 | Viewed by 272 | Submission Open

Keywords: waste valorization; phytochemicals; functional ingredients; green extraction; nutritional enhancement; circular economy; health-promoting compounds; food fortification; shelf-life extension; oxidative stress

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Oxidative Stress in Hearing Loss—2nd Edition

edited by Lei Song and Joseph Santos-Sacchi

submission deadline 30 Apr 2026 | Viewed by 176 | Submission Open

Keywords: ear; outer hair cell; inner ear

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Phytotherapy and Natural Products in the Treatment and Prevention of Chronic Diseases

edited by

Sara Damiano

and

Roberto Ciarcia

submission deadline 30 Apr 2026 | Viewed by 93 | Submission Open

Keywords: chronic diseases; phytotherapy; natural antioxidants; plant-derived compounds

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Antioxidants from Sustainable Food Sources—2nd Edition

edited by

Kevin Kantono

and

Nazimah Hamid

submission deadline 30 Apr 2026 | Viewed by 73 | Submission Open

Keywords: sustainable antioxidants; natural sources; green extraction; functional foods; food system resilience

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Antioxidants Isolation and Characterization

edited by José Luis Todolí Torró and

Ana Beltrán Sanahuja

submission deadline 30 Apr 2026 | Viewed by 67 | Submission Open

Keywords: plant-derived antioxidants; polyphenols; flavonoids; carotenoids; phenolic acids; green extraction techniques; chromatographic and spectroscopic analysis; metabolomics; antioxidant activity evaluation; agro-industrial by-products valorization

(This special issue belongs to the Section Methods for Antioxidants Evaluation/Measurement)

Molecular Crosstalk Between Redox Signaling and Intestinal Health: The Role of Dietary Antioxidants

edited by

Carla Gentile

and Graziella Serio

submission deadline 30 Apr 2026 | Viewed by 66 | Submission Open

Keywords: redox signaling; intestinal inflammation; dietary antioxidants; NF-κ B signaling; Nrf2 signaling; epigenetic regulation; tight junctions; polyphenols; melatonin; phytomelatonin

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Next-Generation Insights into Anthocyanins and Phytopigments: Bioactivity, Bioavailability, and Health Impacts

edited by

Agustín G. Asuero

Noelia Tena

and

Julia Martín

submission deadline 30 Apr 2026 | Viewed by 65 | Submission Open

Keywords: anthocyanins; phytopigments; antioxidant activity; bioavailability; metabolic transformation; dietary supplements; chronic disease prevention

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Oxidative Stress in Cardiovascular Diseases

edited by

Yongting Luo

Junjie Luo

and Peng An

submission deadline 30 Apr 2026 | Viewed by 62 | Submission Open

Keywords: cardiovascular disease; oxidative stress; antioxidant compound; mechanism; therapeutic target

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Anti-Inflammatory Agents from Natural Antioxidants: Discovery, Mechanisms, and Therapeutic Potential

edited by

Young-Chang Cho

submission deadline 30 Apr 2026 | Viewed by 60 | Submission Open

Keywords: oxidative stress; inflammatory responses; antioxidant; anti-inflammation; anti-aging; anticancer; natural products

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Role of Natural Antioxidant Compounds in Slowing Neurodegeneration

edited by

Jessica Maiuolo

submission deadline 30 Apr 2026 | Viewed by 57 | Submission Open

Keywords: neurodegeneration; neurodegenerative diseases; plant extracts; natural compounds; phytochemicals; polyphenols; gut-microbiota; gut– brain axis; brain and short-chain fatty acids

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Role of Antioxidants in Pregnant Women’s and Children’s Health—3rd Edition

edited by

Joanna Gajewska

Jadwiga Ambroszkiewicz

and

Magdalena Chełchowska

submission deadline 30 Apr 2026 | Viewed by 52 | Submission Open

Keywords: antioxidants; oxidative stress; pregnancy; newborns; infants; children; glutathione; adipokines; vitamins; microelements; reproductive health; metabolic disease; lifestyle factors; rare disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

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