Biomarkers of Oxidative Stress in Lung Disease
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 10
Special Issue Editor
Interests: allergy and clinical immunology; mechanisms of airways inflammation; oxidative stress in asthma; atopic dermatitis and COPD; arachidonic acid metabolism; smoking and oxidative stress; microbiota
Special Issue Information
Dear Colleagues,
Oxidative stress is a key mediator/trigger of inflammation, impairment, and injury during the progression of virtually all lung diseases. Specifically, oxidative stress plays a major role in the pathogenesis of various pathologic conditions, including COPD, asthma, chronic bronchitis, COVID-19, and pulmonary fibrosis of various origins. It is also enhanced by environmental influences such as smoking, air pollution, and occupational hazards. Oxidative stress is present in bronchi as well in lung parenchyma. It may influence epithelial cell death and mediator release and cause airway remodeling and fibrosis. Some of the molecular mechanisms of oxidative stress’s influence on lung pathology have been well established, but several, including changes in gene expression and inflammasome activation, remains to be fully elucidated. Therefore, data for signal transduction and clarifying the role of oxidative stress might be of interest.
Interestingly, the role of oxidative stress in allergic inflammation is underappreciated.
Similarly, therapeutic interventions targeting oxidative stress are still far from being introduced in clinical practice.
As Guest Editor, I invite you to contribute to this Special Issue, whose focus will be the role of oxidative stress in lung disease progression and as target of therapeutic interventions.
Prof. Dr. Rafał Pawliczak
Guest Editor
Manuscript Submission Information
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Keywords
- oxidative stress
- reactive oxygen species
- reactive nitrogen species
- antioxidants
- lung inflammation
- bronchial inflammation
- COPD
- asthma
- lung fibrosis
- mitochondria
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