Redox Signaling in Chronic Diseases

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".

Deadline for manuscript submissions: 30 January 2026 | Viewed by 68

Special Issue Editor


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Guest Editor
Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy
Interests: redox modulator; ozone therapy; oxidative stress in chronic diseases; antioxidants; anti-inflammatory agents; gaseous signaling molecules
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Special Issue Information

Dear Colleagues,

Redox signaling plays a pivotal role in the pathogenesis and development of many chronic diseases, such as atherosclerosis, diabetes, COPD, reumatologic diseases, and neurodegenerative diseases.

Keap1-NRF2 complex, FOXO, HIF, and NFkB signaling pathways represent important mechanisms for mantaining physiological redox homeostasis and regulating a large number of cellular functions, as reported by a large number of studies.

For these reasons, a better understanding of redox signaling networks under different physiological and pathological conditions is of critical value for the treatment of chronic oxidative diseases.

This Special Issue thus aims to provide an overview of state-of-the-art and future perspectives in redox-related diseases and associated phenomena (cardiovascular diseases, metabolic disorder, cancer, aging, chronic pulmonary diseases, neurodegenerative disorders).

Original research articles, reviews and short reports—ranging from basic research to clinical applications, in all aspects of redox modulation in chronic diseases—are welcome.

Dr. Emma Borrelli
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • redox signaling
  • chronic oxidative diseases
  • redox modulator
  • oxidative stress
  • antioxidant
  • redox homeostasis

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Published Papers

This special issue is now open for submission.
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