Special Issues

Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Next-Generation Insights into Anthocyanins and Phytopigments: Bioactivity, Bioavailability, and Health Impacts submission deadline 30 Apr 2026 | Viewed by 155 | Submission Open
Keywords: anthocyanins; phytopigments; antioxidant activity; bioavailability; metabolic transformation; dietary supplements; chronic disease prevention
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Mitochondrial and Redox Signaling in Exercise, Aging, and Metabolic Health submission deadline 30 Apr 2026 | Viewed by 140 | Submission Open
Keywords: mitochondria; skeletal muscle; exercise; aging; metabolism; oxidative stress; muscle– brain crosstalk; sarcopenia; osteoporosis; neurodegenerative diseases
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Molecular Crosstalk Between Redox Signaling and Intestinal Health: The Role of Dietary Antioxidants
edited by and Graziella Serio
submission deadline 30 Apr 2026 | Viewed by 134 | Submission Open
Keywords: redox signaling; intestinal inflammation; dietary antioxidants; NF-κ B signaling; Nrf2 signaling; epigenetic regulation; tight junctions; polyphenols; melatonin; phytomelatonin
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidants in Prevention and Treatment of Diabetes
edited by Karima Zitouni and Kenneth Earle
submission deadline 30 Apr 2026 | Viewed by 133 | Submission Open
Keywords: diabetic vasculopathy; oxidative stress; type 2 diabetes; antioxidant defenses
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
The Role of Antioxidants in Pregnant Women’s and Children’s Health—3rd Edition submission deadline 30 Apr 2026 | Viewed by 129 | Submission Open
Keywords: antioxidants; oxidative stress; pregnancy; newborns; infants; children; glutathione; adipokines; vitamins; microelements; reproductive health; metabolic disease; lifestyle factors; rare disease
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidants Isolation and Characterization
edited by José Luis Todolí Torró and
submission deadline 30 Apr 2026 | Viewed by 122 | Submission Open
Keywords: plant-derived antioxidants; polyphenols; flavonoids; carotenoids; phenolic acids; green extraction techniques; chromatographic and spectroscopic analysis; metabolomics; antioxidant activity evaluation; agro-industrial by-products valorization
(This special issue belongs to the Section Methods for Antioxidants Evaluation/Measurement)
Natural Antioxidants from Plants in Combating Metabolism-Related Diseases submission deadline 30 Apr 2026 | Viewed by 114 | Submission Open
Keywords: plant-derived antioxidants; flavonoids; alkaloids; coumarins; polysaccharides; metabolism-related diseases; obesity; diabetes; NAFLD; cardiovascular diseases; neurodegenerative diseases; gut microbiota; extraction and purification; bioactivity evaluation; therapeutic applications
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Innovative Processing Technologies and Their Effects on Antioxidant Activity in Plant-Derived Natural Products
edited by
submission deadline 30 Apr 2026 | Viewed by 100 | Submission Open
Keywords: innovative extraction methodologies; natural antioxidants; oxidative stress modulations; cell-based and biochemical assays
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Advanced in the Protective Action of Antioxidant Signalling Mediators on Skeletal Muscle Regeneration
edited by
submission deadline 30 Apr 2026 | Viewed by 100 | Submission Open
Keywords: skeletal muscle (SkM); antioxidant signalling; reactive oxygen species (ROS); muscle stem cells (MuSCs)
Redox Homeostasis in Poultry/Animal Production―2nd Edition
edited by
submission deadline 30 Apr 2026 | Viewed by 97 | Submission Open
Keywords: redox homeostasis; oxidative stress; antioxidants; transcription factors; immunity; inflammation; poultry; pigs; cattle
Redox Modulation in Neurodegenerative Disorders: A Focus on Epigenetic Regulation
edited by
submission deadline 30 Apr 2026 | Viewed by 86 | Submission Open
Keywords: redox signaling; oxidative stress; epigenetics; DNA methylation; histone modification; chromatin remodeling; noncoding RNA; mitochondrial dysfunction; neurodegeneration; biomarkers
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Peptides submission deadline 10 May 2026 | 4 articles | Viewed by 5112 | Submission Open
Keywords: structure– activity relationships; novel natural or synthetic sources; advanced delivery systems; roles in preventing or alleviating oxidative stress-related diseases.
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Bioactive Antioxidants from Agri-Food Wastes, 2nd Edition submission deadline 10 May 2026 | 1 articles | Viewed by 593 | Submission Open
Keywords: agri-food byproducts; waste; food industry; additives; packaging
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Natural Compounds in Neurogenesis, Neurodevelopment, and the Attenuation of Neurotoxicity: Insights from Animal Models submission deadline 10 May 2026 | Viewed by 140 | Submission Open
Keywords: neurogenesis; neurodevelopment; neurotoxicity; antioxidant activity; brain development
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Health Implications of Vitamin E and Its Analogues and Metabolites
edited by Jean-Marc Zingg, and
submission deadline 15 May 2026 | 1 articles | Viewed by 408 | Submission Open
Keywords: vitamin E; antioxidant; non-antioxidant; bioavailability; bioactivity; signalling; gene expression
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Cigarette Smoke and Oxidative Stress
edited by
submission deadline 20 May 2026 | 6 articles | Viewed by 9436 | Submission Open
Keywords: smoking; cardiovascular diseases; oxidative stress; cigarettes
Redox Regulation in COPD: Therapeutic Implications of Antioxidants submission deadline 20 May 2026 | 2 articles | Viewed by 3064 | Submission Open
Keywords: COPD; oxidative stress; antioxidants; pulmonary diseases; therapeutics
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Phenolics as Antioxidant Agents—2nd Edition
edited by
submission deadline 20 May 2026 | Viewed by 211 | Submission Open
Keywords: antioxidants; bioactive compounds; oxidative stress; structure– activity relationships (SARs); sustainable extraction; green chemistry; therapeutic potential; in vitro and in vivo models; food and biomedical applications
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Antioxidants in Health and Disease: Environmental Challenges, Redox Homeostasis, and Adaptive Responses
edited by
submission deadline 20 May 2026 | Viewed by 112 | Submission Open
Keywords: antioxidants; redox biology; oxidative stress; environmental exposures; adaptive responses; resilience; Nrf2 pathway; endogenous antioxidants; exogenous antioxidants; cellular homeostasis; environmental toxicology; climate-related stress; human health; chronic disease; prevention; therapeutic strategies
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Plant and Algal Antioxidants in Stress Defence
edited by Petra Peharec Štefanić and
submission deadline 20 May 2026 | Viewed by 105 | Submission Open
Keywords: plant antioxidants; algal antioxidants; oxidative stress; bioactive compounds; ROS; abiotic stress; biotic stress; antioxidant enzymes; secondary metabolites; stress physiology; phytochemicals; natural antioxidants
(This special issue belongs to the Section ROS, RNS and RSS)
Antioxidant Research in Chile—2nd Edition submission deadline 30 May 2026 | 7 articles | Viewed by 11912 | Submission Open
Keywords: antioxidants; biotechnology; biomedicine; natural products; nutrition; oxidative stress; Chilean plants of economic importance; polyphenols; flavonoids; anthocyanins; phenolic acids; resveratrol; food waste; plant extracts; neuroinflammation; redox signaling; circular economy; ROS scavengers; antioxidants in industry; entrepreneurship; green startups
Oxidative Stress in Livestock and Poultry—3rd Edition
edited by and
submission deadline 30 May 2026 | 6 articles | Viewed by 11095 | Submission Open
Keywords: oxidative stress; environmental stressors; gut microbiome; antioxidant strategies; epigenetic modifications
Oxidative Stress in Plant Stress and Plant Physiology
edited by
submission deadline 30 May 2026 | 3 articles | Viewed by 3362 | Submission Open
Keywords: ROS signaling; stress adaptive responses; halophyte vs glycophyte; redox homeostasis; molecular crosstalk with  ROS signaling; biotic; abiotic; soil borne; and air pollutants
(This special issue belongs to the Section ROS, RNS and RSS)
Innovative Analytical Pathways: Exploring Phytochemical Profiles and Bioactivities Through Advanced Instrumentation submission deadline 30 May 2026 | 1 articles | Viewed by 1453 | Submission Open
Keywords: phytochemical profiling; bioactivity analysis; pharmacodynamics and pharmacokinetics of antioxidants; advanced instrumentation; natural antioxidants; extraction and isolation techniques; structural characterization; industrial applications of antioxidants; LC-MS; GC-MS; HRMS; NMR; FTIR
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Glutathione Redox Cycle, 2nd Edition
edited by
submission deadline 30 May 2026 | Viewed by 129 | Submission Open
Keywords: glutathione; oxidized glutathione; glutathione metabolism; glutathione biosynthesis; glutathione homeostasis; thiol redox status; disulfide; GSH; GSSG
(This special issue belongs to the Section Antioxidant Enzyme Systems)
The OxInflammation Process and Tissue Repair
edited by Reggiani Vilela Gonçalves, Mariaurea Matias Sarandy and Rômulo Dias Novaes
submission deadline 31 May 2026 | 6 articles | Viewed by 22532 | Submission Open
Keywords: oxidative stress; inflammasome; cytokines; angiogenesis; molecular biology; cellular and molecular mechanisms; diabetes; tissue repair
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Multi-Target Profile of Antioxidant Compounds, Including Repurposing and Combination Strategies—2nd Edition
edited by
submission deadline 31 May 2026 | 5 articles | Viewed by 12631 | Submission Open
Keywords: polypharmacology; multi-target ligands; rational drug; design repurposing; off-target effects; computational techniques
Roles of NADPH Oxidase in Modulation of Signal Transduction and Cellular Metabolism—2nd Edition submission deadline 31 May 2026 | 4 articles | Viewed by 8551 | Submission Open
Keywords: redox signaling; inflammation; NADPH oxidase; ROS; cell metabolism; redox-state; Warburg effect; metabolic reprogramming; tumor microenvironment; cell proliferation
(This special issue belongs to the Section Antioxidant Enzyme Systems)
Innovative Technologies for Detecting Antioxidant Properties and Oxidative Stabilization of Agri-Food Products and Plant Extracts
edited by
submission deadline 31 May 2026 | 3 articles | Viewed by 8512 | Submission Open
Keywords: green extraction; plant extracts; bioactive compounds; flavonoids; polyphenols; detection technologies; antioxidant activity
(This special issue belongs to the Section Methods for Antioxidants Evaluation/Measurement)
Oxidative Stress in Hepatic Diseases
edited by
submission deadline 31 May 2026 | 3 articles | Viewed by 8304 | Submission Open
Keywords: oxidative stress; hepatic diseases; liver fibrosis; reactive oxygen species (ROS); mitochondrial dysfunction; lipid peroxidation; antioxidant defense; non-alcoholic fatty liver disease (NAFLD); alcoholic liver disease; hepatoprotective strategies
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Lipid Peroxidation in Physiology and Chronic Inflammatory Diseases submission deadline 31 May 2026 | 1 articles | Viewed by 8118 | Submission Open
Keywords: lipid peroxidation; oxidative stress; chronic inflammation; antioxidants; reactive lipid species; inflammatory signaling; redox biology; lipid mediators; disease pathogenesis
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress in Animal Reproduction and Nutrition
edited by and
submission deadline 31 May 2026 | 8 articles | Viewed by 8032 | Submission Open
Keywords: oxidative stress; antioxidants; animal reproduction; nutritional regulation; livestock and poultry; mouse or rat model; antioxidant mechanisms; oxidative stress mechanisms
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Cellular ROS and Antioxidants: Physiological and Pathological Role—2nd Edition submission deadline 31 May 2026 | 5 articles | Viewed by 6906 | Submission Open
Keywords: reactive oxygen and nitrogen species; intracellular signaling; oxidative stress; iron metabolism; mitochondrial dysfunction; hypoxia; inflammation; targeted and untargeted antioxidants; gas messengers natural and artificial sources of reactive oxygen species; antioxidant defense systems; small signaling molecules; oxidative stress-driven processes
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Plants and Plant-Based By-Products as Valuable Sources of Antioxidants: Current Tendencies and Achievements in Their Exploitation
edited by Svetlana Momchilova and
submission deadline 31 May 2026 | 4 articles | Viewed by 6305 | Submission Open
Keywords: antioxidants; oxidative stability; antioxidant activity; lipid oxidation; green chemistry; biomass; plants and by-products; herbs; utilization
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Oxidative Stress in Age-Related Diseases submission deadline 31 May 2026 | 2 articles | Viewed by 3780 | Submission Open
Keywords: aging; age-related diseases; frailty; oxidative stress; reductive stress; redox homeostasis; antioxidants
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Bioactive Compounds from Natural Sources with Antioxidant and Anti-Inflammatory Potential
edited by
submission deadline 31 May 2026 | 5 articles | Viewed by 3544 | Submission Open
Keywords: antioxidant; anti-inflammatory; natural compounds; isolation; extraction; molecular mechanism; synergistic effect; clinical trial; bioavailability; analytical method; pharmacodynamics; pharmacokinetics
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Oxidative Stress and NRF2 in Diabetes
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 3354 | Submission Open
Keywords: oxidative stress; NRF2; ROS; diabetes; diabetes-related complications; insulin
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress Mechanisms and Parkinson's Disease Treatment submission deadline 31 May 2026 | 1 articles | Viewed by 3165 | Submission Open
Keywords: Parkinson’ s disease; dopamine; dopamine oxidation; neuromelanin; dopaminergic neurons; antioxidants; neuroprotection; neurodegeneration; oxidative stress; protein degradation dysfunction; neuroinflammation; mitochondrial dysfunction; endoplasmic reticulum stress; alpha-synuclein oligomers; glutathione; glutathione transferase; DT-diaphorase; preclinical model for Parkinson's disease; VMAT2; dopamine transporter; tyrosine hydroxylase; dopamine-derived orto-quinones
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress During Physical Activity
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 2316 | Submission Open
Keywords: physical activity; exercise; oxidative stress; reactive oxygen species (ROS); redox balance; cellular damage; skeletal muscle
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Hydrogen Sulfide, Reactive Sulfur Species, and Donor Compounds: Natural and Synthetic Tools for Physiology and Disease submission deadline 31 May 2026 | 1 articles | Viewed by 2175 | Submission Open
Keywords: hydrogen sulfide; H2S donors; H2S hybrid compounds; H2S sources; pharmacological tools; H2S signaling
Role of Oxidative Stress in Cardiac Remodeling and Heart Failure—3rd Edition submission deadline 31 May 2026 | 1 articles | Viewed by 923 | Submission Open
Keywords: oxidative stress; heart disease; cardiac remodeling; signaling pathways; remodeling; left ventricular dysfunction; heart failure; cardiovascular disease; myocardial damage
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress as a Therapeutic Target of Alzheimer’s Disease—2nd Edition submission deadline 31 May 2026 | 1 articles | Viewed by 713 | Submission Open
Keywords: Alzheimer's disease; oxidative stress; therapeutic target; antioxidant; neurodegeneration
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidants, Metabolic Regulation and Stroke
edited by Indu Dhar
submission deadline 31 May 2026 | 1 articles | Viewed by 633 | Submission Open
Keywords: oxidative stress; metabolic regulation; neuroprotection; antioxidants; stroke
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Redox Regulation of Cancer Metabolism
edited by , Adriana Celesia and Alessia Cardile
submission deadline 31 May 2026 | 1 articles | Viewed by 272 | Submission Open
Keywords: redox homeostasis; cancer metabolism; reactive oxygen species (ROS); metabolic reprogramming; oxidative stress; Nrf2; HIF-1α ; mitochondrial metabolism; antioxidant therapy; metabolic vulnerabilities
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Vitamins, Antioxidants, and Neurodegeneration: Exploring Protective Strategies in Brain Health
edited by
submission deadline 31 May 2026 | Viewed by 269 | Submission Open
Keywords: neurodegenerative diseases; alzheimer's disease; parkinson's disease; amyotrophic lateral sclerosis (ALS); aging populations; vitamins; antioxidants; oxidative stress; neuroinflammation
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
The Effects of Antioxidants as Supplements on Exercise Performance and Recovery
edited by and Rossella Rotondo
submission deadline 31 May 2026 | Viewed by 183 | Submission Open
Keywords: exercise performance; exercise recovery; oxidative stress; antioxidants; sport nutrition; sport supplements; detoxification systems
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant and Antimicrobial Activity of Honey Bee Products—3rd Edition submission deadline 31 May 2026 | Viewed by 182 | Submission Open
Keywords: honey bee products; antioxidant capacity; antimicrobial efficacy; polyphenol content; functional food; health promotion
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Oxidative Stress and Precision Medicine in Cardiometabolic and Cardiovascular Disease: Mechanisms, Biomarkers, and Therapeutic Targets
edited by Leroy Sivappiragasam Pakkiri and Chester Lee Drum
submission deadline 31 May 2026 | Viewed by 163 | Submission Open
Keywords: oxidative stress; precision medicine; cardiometabolic disease; cardiovascular disease; redox signaling
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Inhibition of Oxidative Stress and Related Signaling Pathways in Neuroprotection—3rd Edition submission deadline 31 May 2026 | Viewed by 144 | Submission Open
Keywords: neuroprotection; neurotoxicity; antioxidative vs. prooxidative activity; antioxidant capacity; signaling pathways; redox metals; apoptosis; ferroptosis; cuproptosis; autophagy
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and Neuroinflammation in Alzheimer’s Disease: Molecular Mechanisms and Therapeutic
edited by
submission deadline 31 May 2026 | Viewed by 134 | Submission Open
Keywords: Alzheimer’ s Disease; oxidative stress; neuroinflammation; antioxidants; amyloid beta; tau pathology; mitochondrial dysfunction; micoglia activation; cell death regulation; therapeutic natural products
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
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