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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Oxidative Stress and Inflammation in Osteoarthritis and Rheumatoid Arthritis

edited by

Katarzyna Piotrowska

and

Mateusz Bosiacki

submission deadline 31 Oct 2026 | Viewed by 387 | Submission Open

Keywords: proinflammatory gene transcription; markers of oxidative stress and antioxidant enzyme activity; targeted therapies in OA and RA; translational studies; experimental models including 3D chondrocyte cultures; antioxidant enzyme gene polymorphisms; impacts of diet/dietary supplements and physical activity on inflammatory processes and oxidative balance

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Reactive Oxygen Species in Skeletal Muscle and Adipose Tissue

edited by Jan Górski and

Elzbieta Supruniuk

submission deadline 31 Oct 2026 | Viewed by 362 | Submission Open

Keywords: oxidative stress; antioxidants; myokines; adipokines; skeletal muscle; adipose tissue

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Quantum Biology and Redox Signaling

edited by

Margaret Ahmad

submission deadline 31 Oct 2026 | Viewed by 278 | Submission Open

Keywords: quantum biology; redox signaling; electron transfer; radical pair mechanisms; reactive oxygen species (ROS); spin chemistry; biological electron tunneling; oxidative stress and signaling; quantum effects in living systems; bioenergetics

(This special issue belongs to the Section ROS, RNS and RSS)

Methionine in Redox Signaling, Metabolic Regulation, and Disease

edited by

Jackob Moskovitz

submission deadline 31 Oct 2026 | Viewed by 204 | Submission Open

Keywords: methionine sulfoxide reductase; methionine-1; S-adenosylmethionine; redox regulation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Advanced Bioanalytical Techniques in Antioxidant and Oxidative Stress Research

edited by Tomasz Ligor and

Magdalena Ligor

submission deadline 31 Oct 2026 | Viewed by 189 | Submission Open

Keywords: biomarkers of oxidative stress; antioxidants from natural sources; advanced chromatographic techniques; omics approaches

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Multi-Organ Effects of Alcohol Exposure: Oxidative Mechanisms and Antioxidant Protection

edited by

María Luisa Ojeda Murillo

and

Fátima Nogales Bueno

submission deadline 31 Oct 2026 | Viewed by 185 | Submission Open

Keywords: alcohol consumption; multi-organ damage; oxidative stress; nitrosative stress; antioxidants

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Recent Advances in Applications of Antioxidants in Livestock Health and Reproduction—2nd Edition

edited by Weijun Pang

submission deadline 31 Oct 2026 | Viewed by 171 | Submission Open

Keywords: antioxidants; livestock health; reproduction; production efficiency; disease-resistant ability

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Genetics and Epigenetics of Antioxidants

edited by

Jolanta Dorszewska

and

Richard Siow

submission deadline 31 Oct 2026 | Viewed by 148 | Submission Open

Keywords: antioxidants; oxidative stress; nutrigenetics; epigenetics; SOD; CAT; GPx; personalized nutrition; cancer; neurodegenerative diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Targeting Oxidative Stress in Ischemia/Reperfusion Injury

edited by Kenneth J. Dery

submission deadline 10 Nov 2026 | 3 articles | Viewed by 5336 | Submission Open

Keywords: ischemia/reperfusion injury; reactive oxygen species; redox-regulated molecular and cellular mechanism; antioxidant-based therapeutic strategies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Resilience in Mitochondrial Health and Disease: New Advances in Cellular Defense Mechanisms

edited by

Yuseok Moon

and

Ki Hyung Kim

submission deadline 10 Nov 2026 | 1 articles | Viewed by 2137 | Submission Open

Keywords: mitochondrial redox; mitochondria; cellular conditions; oxidative damage; redox homeostasis; cellular aging; metabolic disorders; cancer; inflammation; obesity; aging; mucosal diseases; neurodegenerative diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Plant‑Derived Essential Oils and Phytochemicals: Dual Antioxidant and Antimicrobial Mechanisms

edited by

Cristina-Mihaela Rîmbu

and

Cristina-Elena Horhogea

submission deadline 15 Nov 2026 | Viewed by 223 | Submission Open

Keywords: plant-derived essential oils and phytochemicals; redox modulation and antioxidant activity; antimicrobial mechanisms and applications

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Natural Antioxidants for Cosmetic Applications

edited by

Rita Cortesi

and

Maddalena Sguizzato

submission deadline 20 Nov 2026 | 4 articles | Viewed by 6738 | Submission Open

Keywords: cosmetic formulations; skin care; oxidative stress; photoprotection

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Role of Mitochondria and ROS in Health and Disease—2nd Edition

edited by

Paola Venditti

Gaetana Napolitano

and

Gianluca Fasciolo

submission deadline 20 Nov 2026 | 3 articles | Viewed by 4372 | Submission Open

Keywords: ROS; mitochondria; antioxidants; oxidative stress; neurological diseases; metabolic diseases; retinal diseases; mitochondrial disfunctions; mitochondria endoplasmic reticulum communication; mitochondrial bioenergetics; ageing; physical activity

(This special issue belongs to the Section ROS, RNS and RSS)

Natural Antioxidants: Multiple Mechanisms for Skin Protection and Skin Disease

edited by

Hang Ma

and

Jean Christopher Chamcheu

submission deadline 30 Nov 2026 | 4 articles | Viewed by 6488 | Submission Open

Keywords: natural products; mechanism(s) of action; multi-omics approaches; target identification; dermatological treatment; skin protection; inflammation; skin cancers; skin aging; cosmeceuticals

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants and Oxidative Stress at the Crossroads of Autophagy and Ferroptosis

edited by

Elzbieta Janda

and Flavia Biamonte

submission deadline 30 Nov 2026 | 4 articles | Viewed by 6195 | Submission Open

Keywords: antioxidants; oxidative stress; ferroptosis; autophagy; molecular mechanisms

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Radiation Exposure and Health: The Role of Oxidative Stress and Inflammatory Response

edited by

Siamak Haghdoost

and

Benjamin Frey

submission deadline 30 Nov 2026 | 3 articles | Viewed by 5128 | Submission Open

Keywords: radiation; inflammatory response; oxidative stress

Role of Antioxidants and Oxidative Stress in Neurodegenerative Diseases

edited by

Barbara Sottero

submission deadline 30 Nov 2026 | 2 articles | Viewed by 4386 | Submission Open

Keywords: neurodegenerative diseases; antioxidants; oxidative stress; Parkinson’s disease; Alzheimer’s disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Impact of Antioxidant and Anti-Inflammatory Functions of HDL in Diseases—3rd Edition

edited by

Carlo Cervellati

and

Judit Marsillach

submission deadline 30 Nov 2026 | 4 articles | Viewed by 3885 | Submission Open

Keywords: paraoxonases; oxidized LDL; high-density lipoproteins; metabolic diseases; apolipoproteins; cardiovascular disease; neurological disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Therapies, Mitochondrial Function, and Transplantation Strategies: Mechanisms and Emerging Therapeutics

edited by

Junhwan Kim

and

P. Singh

submission deadline 30 Nov 2026 | 4 articles | Viewed by 3603 | Submission Open

Keywords: oxidative stress; antioxidant therapies; mitochondrial function; mitochondrial dysfunction

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Cardiovascular Diseases

edited by

Yongting Luo

Junjie Luo

and Peng An

submission deadline 30 Nov 2026 | 2 articles | Viewed by 3346 | Submission Open

Keywords: cardiovascular disease; oxidative stress; antioxidant compound; mechanism; therapeutic target

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Mitochondria, Redox and Pancreatic β-Cells: Maturation, Function and Inflammatory Stress

edited by Sarah Zangen

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2520 | Submission Open

Keywords: pancreatic β-cell mitochondria; redox; ETC dysfunction; electron ROS/RNS; mitophagy; UPR^mt; antioxidant defenses; cytokines; inflammasome; iPSC/islet organoids; biomarkers; therapeutics

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants in Prevention and Treatment of Diabetes

edited by Karima Zitouni and Kenneth Earle

submission deadline 30 Nov 2026 | 3 articles | Viewed by 2231 | Submission Open

Keywords: diabetic vasculopathy; oxidative stress; type 2 diabetes; antioxidant defenses

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants in Food Matrices: From Analytical Advances to Circular and Sustainable Applications

edited by

Sara Jaramillo-Carmona

and

Rafael Guillén Bejarano

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1814 | Submission Open

Keywords: food matrix; bioaccesibility; bioavailability; functionality; by-products; valorization; circular economy

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Next-Generation Insights into Anthocyanins and Phytopigments: Bioactivity, Bioavailability, and Health Impacts

edited by

Agustín G. Asuero

Noelia Tena

and

Julia Martín

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1639 | Submission Open

Keywords: anthocyanins; phytopigments; antioxidant activity; bioavailability; metabolic transformation; dietary supplements; chronic disease prevention

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Melanoma and Redox Dynamics: A Crucial Tug-of-War in Tumor Onset and in Therapy Response

edited by

Cinzia Domenicotti

and

Barbara Marengo

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1348 | Submission Open

Keywords: melanoma; redox homeostasis; ROS; antioxidants; therapy resistance; cancer metabolism; mitochondria; epigenetic changes; innovative therapeutic and experimental approaches

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Therapeutic Potential of Natural Antioxidants in Respiratory Diseases and Airway Inflammation

edited by Yo-Han Han

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1186 | Submission Open

Keywords: natural product; acute/chronic lung injury; inflammation; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

One Health and Oxidative Stress: Environmental Drivers, Molecular Pathways, and Disease Risk

edited by

Francesca Gorini

Andrea Borghini

and

Alessandro Tonacci

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1002 | Submission Open

Keywords: one health; environmental exposures; environmental epidemiology; cardiovascular disease; cancer; mitochondrial dysfunction; epigenetics; oxidative stress; antioxidants; toxicology

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants from Agri-Food Byproducts: Effects on Metabolic Syndrome and Skin Health

edited by

Vincenzo Piccolo

Maria Maisto

and

Ritamaria Di Lorenzo

submission deadline 30 Nov 2026 | 2 articles | Viewed by 940 | Submission Open

Keywords: agri-food byproducts; antioxidants; bioactive compounds; oxidative stress; polyphenols; anti-inflammatory activity; skin health; cosmeceuticals; nutraceuticals; sustainable valorization

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Role of High-Density Lipoprotein—2nd Edition

edited by Paul Durrington

submission deadline 30 Nov 2026 | 1 articles | Viewed by 717 | Submission Open

Keywords: lipoprotein oxidation; cell membrane oxidation; HDL antioxidant activity; glycosylation; atherosclerosis; paraoxonase

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Cardioprotection in Ischemia/Reperfusion Injury: Mechanisms, Biomarkers, and Therapeutic Approaches

edited by Anna Krzywonos-Zawadzka, Agnieszka Jaźwa-Kusior and Iwona Bil-Lula

submission deadline 30 Nov 2026 | Viewed by 478 | Submission Open

Keywords: mitochondrial dysfunction; reactive oxygen species (ROS); cardioprotective strategies; conditioning strategies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Osteoclast Metabolism: Implications for Bone Disease Treatment

edited by

Eiko Sakai

submission deadline 30 Nov 2026 | 2 articles | Viewed by 364 | Submission Open

Keywords: bone; osteoclast; oxidative stress; antioxidants; Nrf2; miRNA; osteoporosis; arthritis; periodontal disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Defenses and Inflammation in Diabetic Retinopathy

edited by Devy Deliyanti

submission deadline 30 Nov 2026 | Viewed by 324 | Submission Open

Keywords: retinal injury; diabetic retinopathy; retinal inflammation; cell death; antioxidant; pro-oxidants; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Advanced in the Protective Action of Antioxidant Signalling Mediators on Skeletal Muscle Regeneration

edited by

Elisabetta Meacci

submission deadline 30 Nov 2026 | Viewed by 276 | Submission Open

Keywords: skeletal muscle (SkM); antioxidant signalling; reactive oxygen species (ROS); muscle stem cells (MuSCs)

Redox Modulation in Neurodegenerative Disorders: A Focus on Epigenetic Regulation

edited by

Simona Daniele

submission deadline 30 Nov 2026 | Viewed by 257 | Submission Open

Keywords: redox signaling; oxidative stress; epigenetics; DNA methylation; histone modification; chromatin remodeling; noncoding RNA; mitochondrial dysfunction; neurodegeneration; biomarkers

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Heart Disease

edited by Aldrin V. Gomes

submission deadline 30 Nov 2026 | Viewed by 206 | Submission Open

Keywords: reactive oxygen species (ROS); redox signaling; ischemia–reperfusion injury; mitochondrial dysfunction; cardiac hypertrophy; myocardial infarction; oxidative stress; antioxidant defense; atherosclerosis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Brain Function—3rd Edition

edited by

Waldo Cerpa

submission deadline 30 Nov 2026 | Viewed by 193 | Submission Open

Keywords: pathophysiological; brain function; oxidative stress ; brain damage ; neurodegeneration; cellular signaling; neurotoxicity; excitotoxicity; synaptic transmission; cognitive function

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Eye Diseases—2nd Edition

edited by

Dhirendra Pratap Singh

and

Eri Kubo

submission deadline 30 Nov 2026 | Viewed by 170 | Submission Open

Keywords: oxidative stress; antioxidants; reactive oxygen species; redox signaling; inflammatory cell death; age-related blinding diseases; age-related macular degeneration; retinal disorder; lens

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress Induced by Environmental Pollution

edited by Lina Mu

submission deadline 30 Nov 2026 | Viewed by 166 | Submission Open

Keywords: environmental exposure; oxidative stress; antioxidants; emerging contaminants; reactive oxygen species (ROS); toxins; chronic diseases; molecular mechanisms; health impacts; environmental health

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Bioactive Compounds of Essential Oils: Chemical Characterization, Antioxidant Mechanisms, and Functional Properties

edited by

Márcio Vargas-Ramella

and

Paulo Cezar Bastianello Campagnol

submission deadline 30 Nov 2026 | Viewed by 159 | Submission Open

Keywords: essential oils; bioactive compounds; antioxidant activity; chemical characterization; structure–activity relationships; stability and degradation kinetics; toxicological evaluation; cytotoxicity

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

The Role of NRF2 in Cardiovascular Health and Disease

edited by Elena N. Dedkova

submission deadline 30 Nov 2026 | Viewed by 153 | Submission Open

Keywords: NRF2 as a therapeutic target; oxidative stress; redox signaling; cardiovascular disease; cardiac remodeling; heart failure; ischemia–reperfusion injury; Friedreich ataxia; mitochondrial dysfunction; inflammation; ferroptosis; autophagy; environmental stressors; translational research; therapeutic targeting; small-molecule activators; biomarkers

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Medicinal Plant Extracts for Modulation of Oxidative Stress and Associated Disorders

edited by

Anca Toiu

submission deadline 30 Nov 2026 | Viewed by 132 | Submission Open

Keywords: phytotherapy; bioactive compounds; natural antioxidants; polyphenolic compounds; oxidative stress modulation; chronic diseases

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Mitochondrial Redox Signalling and Regulated Cell Death Pathways: New Insights into Disease Mechanisms and Therapy

edited by Seung Jae Hyeon

submission deadline 30 Nov 2026 | Viewed by 119 | Submission Open

Keywords: mitochondrial ROS; redox signalling; regulated cell death; oxidative stress; therapeutic targets

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Reactive Oxygen Species in Cancer and Viral Diseases: A Double-Edged Sword

edited by Eduardo Maldonado and

Sandra Pérez

submission deadline 30 Nov 2026 | Viewed by 116 | Submission Open

Keywords: reactive oxygen species (ROS); oxidative stress; mitochondria; cancer; viral infections; redox homeostasis; antioxidant defenses; chemotherapy; electron transport chain; ROS-mediated cytotoxicity

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Imbalance and Antioxidants in Gut–Liver Axis Dysfunction: A Focus on Dysbiosis and Microbial Metabolites

edited by

Agostino Di Ciaula

and Laura Mahdi

submission deadline 30 Nov 2026 | Viewed by 90 | Submission Open

Keywords: gut–liver axis; oxidative stress; dysbiosis; microbial metabolites

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Innovative Processing for Bioactive and Antioxidant Recovery in Foods

edited by

Patroklos Vareltzis

submission deadline 30 Nov 2026 | Viewed by 86 | Submission Open

Keywords: bioactive compounds; antioxidant recovery; innovative extraction techniques

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Antioxidant and Anti-Inflammatory Properties of Mushrooms: From Structure to Functionality

edited by

Michał Swieca

submission deadline 1 Dec 2026 | 3 articles | Viewed by 17515 | Submission Open

Keywords: mushroom; antioxidants; metabolic syndrome; functional food; nutraceuticals; polysaccharides; phenolics; terpenoids

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Redox Mechanisms in Obesity-Induced Organ Injury: Potential Therapeutic Opportunities

edited by

Claudio Pirozzi

and Stefania Melini

submission deadline 10 Dec 2026 | Viewed by 134 | Submission Open

Keywords: redox signaling; oxidative stress; metabolic diseases; mitochondrial dysfunction; inflammation; liver; brain; MAFLD (metabolic dysfunction-associated fatty liver disease); MASH (metabolic dysfunction-associated steatohepatitis); cardiometabolic diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Bioactive Antioxidants from Agri-Food Wastes, 2nd Edition

edited by

Mia Kurek

Sabina Galus

and

Tea Sokač Cvetnić

submission deadline 20 Dec 2026 | 3 articles | Viewed by 3504 | Submission Open

Keywords: agri-food byproducts; waste; food industry; additives; packaging

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Targeting Mitochondrial Dysfunction and Oxidative Stress for Neuroprotection

edited by

Nora Gray

submission deadline 25 Dec 2026 | Viewed by 104 | Submission Open

Keywords: oxidative stress; mitochondrial dysfunction; neurodegeneration; Alzheimer’s disease; Parkinson’s disease; biomarkers

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Iron Metabolism and Oxidative Stress in Brain Ageing and Neurodegenerative Diseases

edited by

Po-Wah So

submission deadline 26 Dec 2026 | Viewed by 267 | Submission Open

Keywords: iron metabolism; redox balance; oxidative stress; neurodegenerative diseases; brain ageing; ferroptosis; metal homeostasis; antioxidant systems; brain iron imaging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

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