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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Emerging Trends in Antioxidant Nutraceuticals

edited by

Andrei Mocan

and

Oleg Frumuzachi

submission deadline 31 Dec 2025 | Viewed by 343 | Submission Open

Keywords: nutraceuticals; diabetes; cancer; oxidative stress; inflammation; antioxidant

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Metabolism and Epigenetics: A Potential Dual Interaction in the Microenvironment of Solid Tumors

edited by

Federico Pio Fabrizio

Lucia Anna Muscarella

Filippo Torrisi

and Sebastiano Giallongo

submission deadline 31 Dec 2025 | Viewed by 270 | Submission Open

Keywords: metabolomics; tumor cell metabolism; tumor microenvironment; cell communication; cell signaling; epigenetics; post-translational modifications; cancer therapy

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Development and Application of Detection Methods for Reactive Oxygen Species and Antioxidants

edited by

Naoya Kishikawa

and

Mahmoud El-Maghrabey

submission deadline 31 Dec 2025 | Viewed by 257 | Submission Open

Keywords: antioxidant extraction; antioxidant assay; sensors for reactive oxygen species (ROS); ROS scavenger assays; biological samples; oxidative stress status; nutritional value; food analysis; bioassays; enzymatic assays; redox cycle; cell imaging

(This special issue belongs to the Section Methods for Antioxidants Evaluation/Measurement)

Radiation Exposure and Health: The Role of Oxidative Stress and Inflammatory Response

edited by

Siamak Haghdoost

and

Benjamin Frey

submission deadline 31 Dec 2025 | Viewed by 224 | Submission Open

Keywords: radiation; inflammatory response; oxidative stress

Natural Antioxidants in Functional Foods

edited by

Angela Cardinali

, Palmira De Bellis and

Anna Rita Bavaro

submission deadline 31 Dec 2025 | Viewed by 214 | Submission Open

Keywords: polyphenols; functional foods; fermentation; antioxidant activity; anti-inflammatory activity

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Role of Dietary Antioxidants in Alleviating Oxidative Stress and Inflammation for Enhanced Immunity in Animals

edited by Yanka D. Karamalakova and

Jie Yin

submission deadline 31 Dec 2025 | Viewed by 181 | Submission Open

Keywords: antioxidants; antioxidant feeding; insect meal; growth performance; digestible energy; nutrient digestibility; blood biochemistry; oxidative stress (OS); lipid peroxidation (MDA); ROS/RNS; superoxide dismutase (SOD); catalase (CAT); glutathione (GSH); glutathione peroxidase (GPx); inflammation markers; total antioxidant capacity (TAC); meat; milk; eggs quality

Novel Strategies for Oxidative Stress Management: Dietary Interventions for Liver and Gut Health

edited by

Antonio Cilla

and

Mussa Makran

submission deadline 31 Dec 2025 | Viewed by 171 | Submission Open

Keywords: antioxidant compounds; phytochemicals; dietary interventions; hepatic disease; intestinal disease; redox homeostasis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants and Dietary Nutrition: Emerging Trends, and Clinical Applications

edited by

Sofia Lotti

and

Raúl Zamora-Ros

submission deadline 31 Dec 2025 | Viewed by 161 | Submission Open

Keywords: antioxidants; oxidative stress; chronic disease prevention; dietary strategies; bioavailability

Antioxidant Natural Products and Peptides in Cosmetics

edited by

Fotini Lamari

Vassiliki Magafa

and

Sophia Hatziantoniou

submission deadline 31 Dec 2025 | Viewed by 157 | Submission Open

Keywords: cosmetics; herbal extracts; natural products; peptides; synthesis; isolation; oxidative stress; emulsions; nanoparticles; fibroblasts; ageing

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Oxidative Stress, Mitochondrial Dysfunction, and Inflammation in Autism

edited by

Abha Chauhan

submission deadline 31 Dec 2025 | Viewed by 151 | Submission Open

Keywords: autism; oxidative stress; mitochondria; inflammation; redox signaling; antioxidants; reactive oxygen species; immune response

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Studies on Antioxidants and Anti-Aging Substances Using Model Organisms and Cell Cultures

edited by

Yoshihiro H. Inoue

submission deadline 31 Dec 2025 | Viewed by 151 | Submission Open

Keywords: antioxidants; anti-aging substances and natural products; experimental animals; 3D cell culture models; organoids; acting mechanisms; antioxidant genes; autophagy; proteasome

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Mitochondrial Dysfunction in Metabolic Disorders

edited by

Pablo M. García-Rovés

Steen Larsen

and Hugo J Alves-Figueiredo

submission deadline 31 Dec 2025 | Viewed by 144 | Submission Open

Keywords: metabolic diseases; oxidative stress; mitochondrial dysfunction; antioxidant therapies; lifestyle interventions; gene therapies; mitochondrial transfer therapies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants for Skin Health—2nd Edition

edited by Rubia Casagrande

submission deadline 31 Dec 2025 | Viewed by 144 | Submission Open

Keywords: skin inflammation; cytokine; skin oxidative stress; Nrf2; reduced glutathione; ultraviolet irradiation; drug delivery; flavonoid; terpenes; specialized pro-resolution lipid mediators

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Editorial Board Members’ Collection Series: Advances in Redox-Tools and Therapies in Cardiovascular Disease

edited by

Andreas Daiber

Albino Carrizzo

and

Moo-Yeol Lee

submission deadline 31 Dec 2025 | Viewed by 138 | Submission Open

Keywords: cardiovascular disease; oxidative stress; inflammation; reactive oxygen species; redox signalling

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Sustainable Strategies for Natural Antioxidant Utilization

edited by

Vlasios Goulas

and Atalanti Christou

submission deadline 31 Dec 2025 | Viewed by 128 | Submission Open

Keywords: extraction; antioxidants; polyphenols; phytochemicals; green chemistry; sustainable process; natural products; drug discovery; formulation; natural product analysis

Bioavailability of Antioxidants: From Omics Insights to Health Outcomes

edited by

Pascual García-Pérez

submission deadline 31 Dec 2025 | Viewed by 123 | Submission Open

Keywords: bioavailability; nutrigenomics; metabolomics; gut microbiota; dietary polyphenols; functional foods; biotransformation; systems biology; antioxidants; bioactivity

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Algal Antioxidants: Physiology, Metabolism, and Evolution

edited by

Shan Lu

submission deadline 31 Dec 2025 | Viewed by 111 | Submission Open

Keywords: algae; antioxidant; oxidative stresses; algal physiology

Redox Regulation of Plant Growth and Development

edited by Judit Dobránszki and

Judit Remenyik

submission deadline 31 Dec 2025 | Viewed by 103 | Submission Open

Keywords: plant biology; ascorbate; free-radical scavenging; glutathione; heat shock proteins; melatonin; oxidative stress; plant growth and development; redox homeostasis; RNP; ROS; plant stress mitigation; plant stress adaptation; transcription factors

(This special issue belongs to the Section ROS, RNS and RSS)

Hydrogen Sulfide and Its Role in Inflammatory and Degenerative Joint Diseases

edited by Guenter Steiner and Burkhard Klösch

submission deadline 31 Dec 2025 | Viewed by 91 | Submission Open

Keywords: hydrogen sulfide; inflammation; antioxidant; osteoarthritis; rheumatoid arthritis; degeneration; chondrocyte; monocyte; fibroblast; drug development

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Adaptive Responses in Space Medicine and Physiology

edited by

Dawon Kang

submission deadline 31 Dec 2025 | Viewed by 81 | Submission Open

Keywords: antioxidant defense ; microgravity ; oxidative stress ; radiation ; space medicine ; space physiology

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Biomarkers of Oxidative Stress in Lung Disease

edited by

Rafał Pawliczak

submission deadline 31 Dec 2025 | Viewed by 76 | Submission Open

Keywords: oxidative stress; reactive oxygen species; reactive nitrogen species; antioxidants; lung inflammation; bronchial inflammation; COPD; asthma; lung fibrosis; mitochondria

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Phytochemicals for Promoting Human Health and Well-Being

edited by

Teresa Mencherini

Francesca Sansone

and

Tiziana Esposito

submission deadline 10 Jan 2026 | 3 articles | Viewed by 2103 | Submission Open

Keywords: antioxidant phytochemicals; oxidative stress; health promotion; chronic disease; functional foods; nutraceuticals

Antioxidant Effects of Natural Compounds on Cell Metabolism

edited by Ester Tellone and Annamaria Russo

submission deadline 12 Jan 2026 | 2 articles | Viewed by 2779 | Submission Open

Keywords: antioxidants; metabolic pathways; dietary intake; blood cells; bioactive compounds

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Mitochondrial Oxidative Stress in Aging and Disease—2nd Edition

edited by

Angela Maria Serena Lezza

and

Vito Pesce

submission deadline 15 Jan 2026 | 7 articles | Viewed by 14161 | Submission Open

Keywords: mitochondrial oxidative stress in aging; mitochondrial oxidative stress in age-related or metabolic diseases; mitochondrial signaling via ROS in diseases; mitochondrial oxidative stress and genomic instability; mitochondrial oxidative stress and inflammation; antioxidants as novel therapeutic approaches; mitochondrial pathologies; aging; mitochondrial

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Hydrophilic and Lipophilic Antioxidants in Foods and Food Processing

edited by

Volker Böhm

submission deadline 15 Jan 2026 | Viewed by 90 | Submission Open

Keywords: antioxidant activity; antioxidant capacity; antioxidant mechanisms; carotenoids; polyphenols; vitamin C; vitamin E; impact of food processing

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Exploring the Role of Polyphenols in Oxidative Stress and Cellular Protection

edited by

Lucia Gimeno-Mallench

submission deadline 20 Jan 2026 | 1 articles | Viewed by 1184 | Submission Open

Keywords: polyphenol; oxidative stress; cellular signaling; metabolic pathways

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Systems in Plants

edited by

Francisco Espinosa Borreguero

, Ilda Jesús Casimiro Felicio and

Inmaculada Garrido Carballo

submission deadline 20 Jan 2026 | 2 articles | Viewed by 1026 | Submission Open

Keywords: enzymatic antioxidants; non-enzymatic antioxidants; nitro-oxidative stress; reactive oxygen species; reactive nitrogen species; ROS and RNS signaling

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Antioxidants and Multifunction Photoprotection—2nd Edition

edited by

André Rolim Baby

and

Catarina Rosado

submission deadline 20 Jan 2026 | Viewed by 111 | Submission Open

Keywords: natural and synthetic antioxidants; sunscreens; multifunctional products; safety and efficacy establishment; product technologies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Advances in Peroxiredoxin Biology

edited by Mikael Molin and Cecilia Picazo

submission deadline 23 Jan 2026 | Viewed by 95 | Submission Open

Keywords: oxidative stress; aging; age-related diseases; H2O2 signaling; redox regulation

(This special issue belongs to the Section Antioxidant Enzyme Systems)

Interplay Between Gut Microbiota and Oxidative Stress

edited by

Sunmin Park

submission deadline 25 Jan 2026 | Viewed by 147 | Submission Open

Keywords: gut microbiota; redox; human health; gut homeostasis

Redox Balance and Autophagy in Neuroinflammation

edited by

Anna Colell

and

Vicente Roca-Agujetas

submission deadline 26 Jan 2026 | Viewed by 225 | Submission Open

Keywords: oxidative stress/oxidative damage ; reactive oxygen species (ROS) ; redox homeostasis ; autophagy ; lysosomal clearance ; proteinopathies ; neuroinflammation ; neurological disorders ; cellular homeostasis ; neuroprotection

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Effect of Oxidative Stress on Reproduction and Development—3rd Edition

edited by

Giulia Guerriero

and

Gerardino D’Errico

submission deadline 30 Jan 2026 | 4 articles | Viewed by 3195 | Submission Open

Keywords: free radicals and antioxidants; oxidative stress in male and female reproduction; mitochondria; gametogenesis; assisted reproduction; thermal fertility limit (TFL); climate change; one-health; biodiversity conservation and sustainability; reproduction; development and nutrigenomics; methods for reactive oxygen species detection and antioxidant property determination.

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Something Is Rotten in the State of Redox—2nd Edition

edited by

Claus Jacob

Muhammad Jawad Nasim

and

Ahmad Yaman Abdin

submission deadline 30 Jan 2026 | Viewed by 343 | Submission Open

Keywords: antioxidants; antioxidant mechanisms; ageing and age-related diseases; oxidative stress; redox biology

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Environmental Risk Factors and Oxidative Stress in the Retina

edited by

Adrian Gericke

submission deadline 30 Jan 2026 | Viewed by 237 | Submission Open

Keywords: environment; pollution; oxidative stress; retina

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Diabetic Retinopathy

edited by Tatsuya Mimura

submission deadline 30 Jan 2026 | Viewed by 211 | Submission Open

Keywords: diabetic retinopaty; oxidative stress; antioxidants; inflammation; environmental factor

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Signaling in Chronic Diseases

edited by

Emma Borrelli

submission deadline 30 Jan 2026 | Viewed by 106 | Submission Open

Keywords: redox signaling; chronic oxidative diseases; redox modulator; oxidative stress; antioxidant; redox homeostasis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Regulation by One-Electron Transferring Flavoproteins: Catalysis and Metabolism

edited by

Daisuke Seo

and

Narimantas K. Cenas

submission deadline 30 Jan 2026 | Viewed by 67 | Submission Open

Keywords: flavin mononucleotide (FMN); flavin adenine dinucleotide (FAD); single-electron transfer; free radicals; reactive oxygen species (ROS); mitochondrial respiration; photosynthesis; nitrogen fixation; electron flux bifurcation; immune response; semiquinone

(This special issue belongs to the Section Antioxidant Enzyme Systems)

Redox Regulation in Animal Reproduction

edited by Zhongliang Jiang

submission deadline 31 Jan 2026 | 9 articles | Viewed by 23756 | Submission Open

Keywords: spermatogenesis; follicular atresia; oocyte maturation; granulosa cells; hormone regulation; autophagy; apoptosis; oxidative stress; signaling regulation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Natural Antioxidants and Aquatic Animal Health—2nd Edition

edited by

Rui Jia

submission deadline 31 Jan 2026 | 6 articles | Viewed by 4902 | Submission Open

Keywords: natural antioxidants; oxidative stress; medicinal plants; aquatic animals; feed additives

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Effect of Nutritional Intervention and Diet on Oxidative Stress and Human Diseases

edited by

Josep A. Tur

, Cristina Bouzas and

Margalida Monserrat-Mesquida

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2450 | Submission Open

Keywords: nutrition; diet; oxidative stress; inflammation; human chronic diseases; supplements; cardiovascular diseases; diabetes; obesity

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Diabetic Retinopathy and Oxidative Stress: Molecular Mechanisms, Diagnostic Strategies, and Advances in Antioxidant Therapies

edited by

Ángel Luis Ortega

and

Juan Gambini

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2178 | Submission Open

Keywords: diabetic retinopathy; natural antioxidants; oxidative stress; epigenetic mechanisms; biomarkers; diagnostic methods

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Human Reproduction

edited by Sofoklis Stavros and Despoina Mavrogianni

submission deadline 31 Jan 2026 | Viewed by 1517 | Submission Open

Keywords: reproduction; oxidative stress; ROS; pregnancy

Antioxidants Benefits in Aquaculture—3rd Edition

edited by

Ángel Isidro Cámpa-Córdova

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1353 | Submission Open

Keywords: aquaculture; invertebrates; vertebrates; oxidative stress; antioxidant response; antioxidant enzymes; antioxidant gene expression; antioxidant products

Innovations in Drug Delivery Systems for Antioxidant-Based Therapeutic Agents

edited by

Judit Váradi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1156 | Submission Open

Keywords: antioxidant; bioaccessibility/bioavailability; stability; controlled release; drug delivery system; nanoparticles; nano-carriers

Antioxidants from the Perspective of Environmental Physiology and Pathology

edited by

Gianfranco Santovito

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1065 | Submission Open

Keywords: antioxidants; environmental stress; pollutants; health; oxidative stress

Lipotoxicity in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Its Therapeutic Control

edited by

Isao Ishii

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1003 | Submission Open

Keywords: metabolic dysfunction– associated steatotic liver disease (MASLD); metabolic dysfunction– associated steatohepatitis (MASH); fatty liver; lipotoxicity; ferroptosis; inflammation; fibrosis; Fenton reaction; thyroid hormone receptor-beta (THR-β ) agonist; peroxisome proliferator-activated receptor (PPAR) agonist; farnesoid X receptor (FXR) agonist

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Role of Antioxidants in the Interplay Between Gut Microbiota and Cardiovascular Disease

edited by

Thea Magrone

and

Luigi Santacroce

submission deadline 31 Jan 2026 | 1 articles | Viewed by 986 | Submission Open

Keywords: antioxidants; cardiovascular diseases; diet; gut microbiota; physical activity; signalling pathways; senescence

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants from the Sea and Their Application

edited by

Daniela Giordano

and

Chiara Lauritano

submission deadline 31 Jan 2026 | Viewed by 399 | Submission Open

Keywords: marine natural products; marine enzymes; marine nutraceuticals; marine cosmeceuticals; food supplements; antioxidant mechanisms of action; structure– function relationship; antioxidant capacity; biotechnological application; biotechnological production

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Natural Antioxidants in Counteracting Mycotoxin and Heavy Metal Toxicity

edited by

Shusheng Tang

and Xingyao Pei

submission deadline 31 Jan 2026 | Viewed by 365 | Submission Open

Keywords: natural antioxidants; mycotoxins; heavy metal; detoxification

Oxidative Stress and Inflammation in Heart Failure

edited by Camilla Hage

submission deadline 31 Jan 2026 | Viewed by 196 | Submission Open

Keywords: heart failure; oxidative stress; HFrEF; HFpEF; reactive oxygen species; nitric oxide; cardiomyocytes; cardiomyopathies; cardiac dysfunction

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

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