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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Potential Health Benefits of Dietary Antioxidants

edited by

Irene Dini

submission deadline 31 Oct 2025 | 12 articles | Viewed by 51578 | Submission Open

Keywords: food antioxidants; food supplements; antioxidant activity; food antioxidant isolation; food antioxidant characterization; analytical method validation; antioxidant bioavailability; circular economy; sustainability

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Regulatory Effects of Curcumin, 2nd Edition

edited by

Jean-Marc Zingg

Kiyotaka Nakagawa

and

Taiki Miyazawa

submission deadline 31 Oct 2025 | 4 articles | Viewed by 32469 | Submission Open

Keywords: curcumin; antioxidant; prooxidant; bioavailability; bioactivity

Oxidative Stress and Liver Disease

edited by Alejandra Espinosa Escalona

submission deadline 31 Oct 2025 | 11 articles | Viewed by 23134 | Submission Open

Keywords: oxidative stress; antioxidants; MAFLD; NAFLD; obesity

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Role of High-Density Lipoprotein

edited by Paul Durrington

submission deadline 31 Oct 2025 | 8 articles | Viewed by 20712 | Submission Open

Keywords: lipoprotein oxidation; cell membrane oxidation; HDL antioxidant activity; glycosylation; atherosclerosis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress as a Therapeutic Target of Alzheimer’s Disease

edited by

Marcello Leopoldo

and

Leonardo Brunetti

submission deadline 31 Oct 2025 | 7 articles | Viewed by 19835 | Submission Open

Keywords: Alzheimer's disease; neuroinflammation; therapeutic agent; oxidative stress

The Role of Natural Antioxidants in Fruits and Vegetables in Human Health

edited by

Antonio Barberis

submission deadline 31 Oct 2025 | 3 articles | Viewed by 19698 | Submission Open

Keywords: antioxidants; anti-inflammation; oxidative stress; fruits; vegetables; oxidation reactions; functional foods

Oxidative Stress Induced by Air Pollution, 2nd Edition

edited by

Yasuhiro Yoshida

submission deadline 31 Oct 2025 | 6 articles | Viewed by 13150 | Submission Open

Keywords: particulate matter; air pollution; oxidative stress; reactive oxygen species; inflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Anti-Cancer Potential of Plant-Based Antioxidants

edited by

Javier Espino

María Garrido

and

Jonathan Delgado-Adamez

submission deadline 31 Oct 2025 | 7 articles | Viewed by 12397 | Submission Open

Keywords: cancer; antitumor activity; medicinal plants; natural antioxidants; polyphenols; terpenoids; carotenoids

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Implication of Oxidative Stress in Promoting Cellular Senescence and Associated Pathologies—2nd Edition

edited by

Alexandra Barbouti

submission deadline 31 Oct 2025 | 7 articles | Viewed by 11854 | Submission Open

Keywords: oxidative stress; free radicals; reactive oxygen species (ROS); cellular senescence; ageing; age-related pathologies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Reactive Oxygen Species and Growth Factors in Photodynamic Therapy (PDT), Photobiomodulation (PBM), and Radiation Therapy (RT)

edited by Timothy C. Zhu and Brian C. Wilson

submission deadline 31 Oct 2025 | 5 articles | Viewed by 10012 | Submission Open

Keywords: reactive oxygen species (ROS); singlet oxygen (SO); radiation; photodynamic therapy; cancers

(This special issue belongs to the Section ROS, RNS and RSS)

Green Extraction of Antioxidant from Natural Source

edited by

Jolanta Flieger

submission deadline 31 Oct 2025 | 6 articles | Viewed by 9790 | Submission Open

Keywords: green extraction techniques ; supercritical fluid extraction ; ionic liquid (IL)-based extraction; microwave-assisted extraction; antioxidants; plants; cosmetic formulation

Oxidative Stress and Inflammation in Bone Metabolism and Diseases

edited by

Jin Kyeong Choi

submission deadline 31 Oct 2025 | 4 articles | Viewed by 8829 | Submission Open

Keywords: oxidative stress; immune system; inflammation; joint inflammation; bone; metabolism pathways

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Valorization of Waste Through Antioxidant Extraction and Utilization

edited by

Andrés Moreno

submission deadline 31 Oct 2025 | 4 articles | Viewed by 7257 | Submission Open

Keywords: valorization; waste management; green extraction; antioxidants; value-added products; by-products

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Antioxidant Activities of Phytochemicals in Fruits and Vegetables

edited by

Wen Qin

submission deadline 31 Oct 2025 | 3 articles | Viewed by 5885 | Submission Open

Keywords: ROS and oxidative stress; green and efficient extraction technology of phytochemicals; antioxidant activity of phytochemicals in fruits and vegetables; polyphenols and polysaccharides in fruits and vegetables; phytochemicals and inflammation

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Novel Approaches in Natural Occuring Antioxidants in the Prevention and Treatment of Chronic Diseases, 2nd Edition

edited by

Christos Kontogiorgis

submission deadline 31 Oct 2025 | 2 articles | Viewed by 5874 | Submission Open

Keywords: nutracuticals; antioxidants; phytochemicals; in vitro studies; in vivo studies; extracts; isolated compounds; chronic diseases; prevention; treatment; therapeutic

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

From Waste to Health: Upcycling Agrifood By-Products into Functional Antioxidant-Rich Ingredients and Products

edited by

Ítala Marx

and

Feliciano Priego-Capote

submission deadline 31 Oct 2025 | 3 articles | Viewed by 5530 | Submission Open

Keywords: antioxidant activity; oxidative stress; reactive oxygen species; polyphenols; bioactive compounds; functional ingredients; health-promoting formulations; agrifood waste; green extraction technologies; emerging analytical methods

Heme Oxygenase in Health and Disease: New Insights and Future Directions

edited by

J. Catharina Duvigneau

submission deadline 31 Oct 2025 | 2 articles | Viewed by 5152 | Submission Open

Keywords: enzyme activity; ferroptosis; carbon monoxide; oxidative stress; reactive oxygen and nitrogen species; heme proteins; heme degradation; heme responsive elements; heme regulation

(This special issue belongs to the Section Antioxidant Enzyme Systems)

Oxidative Stress Induced by Micro(Nano)plastics

edited by

Lavinia Casati

Alessandro Villa

and

Marco Parolini

submission deadline 31 Oct 2025 | 1 articles | Viewed by 5044 | Submission Open

Keywords: micro(nano)plastics; oxidative stress; One Health; in vitro and in vivo models; organisms; cellular microenvironment

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Cellular ROS and Antioxidants: Physiological and Pathological Role—2nd Edition

edited by

Andrey V. Kozlov

Mihály Boros

and

Salvatore Nesci

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4506 | Submission Open

Keywords: reactive oxygen and nitrogen species; intracellular signaling; oxidative stress; iron metabolism; mitochondrial dysfunction; hypoxia; inflammation; targeted and untargeted antioxidants; gas messengers natural and artificial sources of reactive oxygen species; antioxidant defense systems; small signaling molecules; oxidative stress-driven processes

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Phytochemicals Against Oxidative Stress: Polypharmacological Strategies for Aging-Related Disease

edited by

and

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2753 | Submission Open

Keywords: phytochemicals; antioxidants; systems biology; oxidative stress; hair loss; skin aging

Plants and Plant-Based By-Products as Valuable Sources of Antioxidants: Current Tendencies and Achievements in Their Exploitation

edited by Svetlana Momchilova and

Adriana Slavova-Kazakova

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2670 | Submission Open

Keywords: antioxidants; oxidative stability; antioxidant activity; lipid oxidation; green chemistry; biomass; plants and by-products; herbs; utilization

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Olive Antioxidants: Extraction, Biological Activity and Practical Applications—3rd Edition

edited by

Juan Fernández-Bolaños

and

Alejandra Bermudez-Oria

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2569 | Submission Open

Keywords: antioxidant effect; olive oil; olive by-products; olive leaves; polyphenols; carotenoids; polysaccharide– polyphenol complexes; vitamin E; health; Mediterranean diet

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Redox Regulation in COPD: Therapeutic Implications of Antioxidants

edited by

Samuel Santos Valença

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1896 | Submission Open

Keywords: COPD; oxidative stress; antioxidants; pulmonary diseases; therapeutics

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants in Cardiovascular Medicine: Emerging Trends and Future Perspectives

edited by

Matteo Becatti

and

Claudia Fiorillo

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1253 | Submission Open

Keywords: cardiovascular disease; CVD; atherosclerosis; hypertension; heart failure; ischemic heart disease; vascular aging; myocardial remodeling

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Sperm: Technical, Biological and Clinical Aspects—2nd Edition

edited by

Monica Muratori

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1096 | Submission Open

Keywords: male infertility; ROS; oxidative sperm DNA damage; sperm DNA fragmentation; sperm epigenetic damage; assisted reproductive techniques; in vitro sperm manipulation; antioxidants; embryo development; pregnancy

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Applications and Health Benefits of Novel Antioxidant Biomaterials—2nd Edition

edited by

Washington Luiz Esteves Magalhães

and Tielidy Lima

submission deadline 31 Oct 2025 | Viewed by 292 | Submission Open

Keywords: antioxidant biomaterials; tissue regeneration; biocompatibility; controlled release; premature aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Respiratory Diseases—Second Edition

edited by

Sabina Galiniak

and

Stephen M. Black

submission deadline 31 Oct 2025 | Viewed by 289 | Submission Open

Keywords: reactive oxygen species; inflammation; antioxidant therapy; chronic obstructive pulmonary disease; asthma; cystic fibrosis; nitrosative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Bioactive Compounds from Natural Sources with Antioxidant and Anti-Inflammatory Potential

edited by

Chun Guang Li

submission deadline 31 Oct 2025 | Viewed by 238 | Submission Open

Keywords: antioxidant; anti-inflammatory; natural compounds; isolation; extraction; molecular mechanism; synergistic effect; clinical trial; bioavailability; analytical method; pharmacodynamics; pharmacokinetics

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Vitamins, Antioxidants, and Neurodegeneration: Exploring Protective Strategies in Brain Health

edited by

Maria Morello

submission deadline 31 Oct 2025 | Viewed by 180 | Submission Open

Keywords: neurodegenerative diseases; alzheimer's disease; parkinson's disease; amyotrophic lateral sclerosis (ALS); aging populations; vitamins; antioxidants; oxidative stress; neuroinflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Role of Oxidative Stress in Cardiac Remodeling and Heart Failure—3rd Edition

edited by

Marina Politi Okoshi

Elida Paula Benquique Ojopi

and

Luana Urbano Pagan

submission deadline 31 Oct 2025 | Viewed by 173 | Submission Open

Keywords: oxidative stress; heart disease; cardiac remodeling; signaling pathways; remodeling; left ventricular dysfunction; heart failure; cardiovascular disease; myocardial damage

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

NADPH Oxidases (NOXs)

edited by David W. Stepp

submission deadline 10 Nov 2025 | 8 articles | Viewed by 14188 | Submission Open

Keywords: NADPH oxidases; reactive oxygen species; redox signaling; cardiovascular diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Roles of NADPH Oxidase in Modulation of Signal Transduction and Cellular Metabolism—2nd Edition

edited by

Rosario Ammendola

and

Fabio Cattaneo

submission deadline 10 Nov 2025 | 3 articles | Viewed by 6360 | Submission Open

Keywords: redox signaling; inflammation; NADPH oxidase; ROS; cell metabolism; redox-state; Warburg effect; metabolic reprogramming; tumor microenvironment; cell proliferation

(This special issue belongs to the Section Antioxidant Enzyme Systems)

Oxidative Stress and NRF2 in Health and Disease—2nd Edition

edited by

Lidija Milković

submission deadline 20 Nov 2025 | 9 articles | Viewed by 16762 | Submission Open

Keywords: oxidative stress; redox signaling; NRF2 and its regulation; redox-modifying therapeutic approach; omics approach; physiology; non-communicable diseases; metabolism; aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Alcohol-Induced Oxidative Stress in Health and Disease, 2nd Edition

edited by

Marco Fiore

submission deadline 20 Nov 2025 | 3 articles | Viewed by 4139 | Submission Open

Keywords: alcohol; alcohol use disorder; reactive oxygen species; antioxidant defense

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Hepatic Diseases

edited by

Miquel Mulero

submission deadline 21 Nov 2025 | 3 articles | Viewed by 5508 | Submission Open

Keywords: oxidative stress; hepatic diseases; liver fibrosis; reactive oxygen species (ROS); mitochondrial dysfunction; lipid peroxidation; antioxidant defense; non-alcoholic fatty liver disease (NAFLD); alcoholic liver disease; hepatoprotective strategies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants from Food and Food Wastes for Nutraceutical, Pharmaceutical and Cosmetic Fields

edited by Monica Locatelli and

Vincenzo Disca

submission deadline 25 Nov 2025 | 8 articles | Viewed by 15752 | Submission Open

Keywords: phenolic compounds; analytical methods; bioactivities; green extraction; functional ingredients; food supplements; by-products and up-cycled ingredients; nutraceutical; cosmetics; bioaccessibility

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Antioxidant Compounds and Health Benefits of Mediterranean Functional Food

edited by

Stefania D'Angelo

submission deadline 25 Nov 2025 | 2 articles | Viewed by 3806 | Submission Open

Keywords: antioxidants; anti-inflammatory; anti-obesity; functional food; human health; Mediterranean diet; nutraceuticals; nutrition; oxidative stress; phytochemicals; polyphenols

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Oxidative Stress in Animal Reproduction and Nutrition

edited by

Fang Chen

and

Jun Chen

submission deadline 28 Nov 2025 | 3 articles | Viewed by 3441 | Submission Open

Keywords: oxidative stress; antioxidants; animal reproduction; nutritional regulation; livestock and poultry; mouse or rat model; antioxidant mechanisms; oxidative stress mechanisms

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants in Meat and Meat Products

edited by

Rubén Domínguez-Valencia

and

Mirian Pateiro

submission deadline 28 Nov 2025 | Viewed by 230 | Submission Open

Keywords: natural antioxidants; oxidative degradation; meat shelf-life; food quality; functional food; bioactive compounds; antioxidant active packaging

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Antioxidants and Retinal Diseases—2nd Edition

edited by

Francisco J. Romero

and Jorge M. Barcia

submission deadline 30 Nov 2025 | 8 articles | Viewed by 28958 | Submission Open

Keywords: retinal diseases; antioxidants; oxygen species; extracellular vesicles; miRNA

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Therapy for Obesity-Related Diseases

edited by

Seyed Khosrow Tayebati

submission deadline 30 Nov 2025 | 8 articles | Viewed by 17667 | Submission Open

Keywords: obesity; inflammation; oxidative stress; organ damage; natural antioxidants; synthetic antioxidants; mechanisms of action; therapeutical approaches

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Natural Products: Biological, Antioxidant Properties and Health Effects—4th Edition

edited by

Evangelos Zoidis

submission deadline 30 Nov 2025 | 9 articles | Viewed by 15044 | Submission Open

Keywords: algal antioxidants; agricultural by-products; algae; bioactive compounds; cancer; cardiovascular diseases; essential oils; inflammatory diseases; marine organisms; metabolic diseases; oxidative stress; phytochemicals; polyphenols; radical scavenging; shelf life; waste products

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Free Radicals, Antioxidants, and Oxidative Stress in Aging and Age-Related Diseases—2nd Edition

edited by

Abdelouahed Khalil

and

Tamas Fulop

submission deadline 30 Nov 2025 | 5 articles | Viewed by 14546 | Submission Open

Keywords: aging; oxidative stress; age-related diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress-Related Mechanisms and Antioxidant Therapy in Cancer

edited by

and

submission deadline 30 Nov 2025 | 4 articles | Viewed by 12954 | Submission Open

Keywords: ascorbate; vitamin C; cancer therapy; cancer prevention; antioxidants; prooxidants; oxidative stress; epigenetic activity

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Novel Antioxidants for Animal Nutrition—2nd Edition

edited by

Matteo Dell'Anno

and

Luciana Rossi

submission deadline 30 Nov 2025 | 6 articles | Viewed by 11462 | Submission Open

Keywords: nutrition; functional diets; innovative antioxidants; feed additives; natural extracts; disease prevention; oxidative stress; one health

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Inhibition of Oxidative Stress and Related Signaling Pathways in Neuroprotection—2nd Edition

edited by

Maja Jazvinšćak Jembrek

and

Josipa Vlainić

submission deadline 30 Nov 2025 | 5 articles | Viewed by 8873 | Submission Open

Keywords: neuroprotection; neurotoxicity; antioxidative vs. proxidative; oxidative stress; signaling pathways; redox metals

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Eye Diseases

edited by

Dhirendra Pratap Singh

and

Eri Kubo

submission deadline 30 Nov 2025 | 5 articles | Viewed by 8756 | Submission Open

Keywords: oxidative stress; antioxidants; reactive oxygen species; redox signaling; inflammatory cell death; age-related blinding diseases; glaucoma; cataract; age-related macular degeneration; gene regulation; retinal disorder; dry eye disorder; corneal diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Reactive Oxygen and Nitrogen Species in Plants―2nd Edition

edited by

Francisco J. Corpas

Rosa M. Rivero

and

José M. Palma

submission deadline 30 Nov 2025 | 4 articles | Viewed by 7681 | Submission Open

Keywords: antioxidants; hydrogen peroxide; nitric oxide; nitro-oxidative stress; ROS; RNS; hydrogen sulfide; melatonin

(This special issue belongs to the Section ROS, RNS and RSS)

The Interaction Between Gut Microbiota and Host Oxidative Stress

edited by

Jie Yin

submission deadline 30 Nov 2025 | 3 articles | Viewed by 6552 | Submission Open

Keywords: oxidative stress; antioxidants; gut microbiome; immunity

Innovative Technologies for Detecting Antioxidant Properties and Oxidative Stabilization of Agri-Food Products and Plant Extracts

edited by

Chao Hui Feng

submission deadline 30 Nov 2025 | 3 articles | Viewed by 6145 | Submission Open

Keywords: green extraction; plant extracts; bioactive compounds; flavonoids; polyphenols; detection technologies; antioxidant activity

(This special issue belongs to the Section Methods for Antioxidants Evaluation/Measurement)

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