Natural Antioxidants in Counteracting Mycotoxin and Heavy Metal Toxicity

Dear Colleagues,

Mycotoxins and heavy metals are pervasive environmental contaminants, posing significant global threats to human and animal health through food chain contamination and environmental exposure. Their toxicity mechanisms, particularly the induction of oxidative stress, are major contributors to cellular damage, organ dysfunction, and chronic diseases. Natural antioxidants, including plant-derived polyphenols, flavonoids, terpenoids, vitamins, and microbial metabolites, offer immense potential in mitigating these toxic effects. These compounds often function through potent antioxidant activities, directly scavenging reactive oxygen species and enhancing endogenous antioxidant defenses. This Special Issue aims to compile cutting-edge research and reviews exploring the protective roles and mechanisms of natural antioxidants against key mycotoxins (aflatoxin, ochratoxin, deoxynivalenol, zearalenone, fumonisin) and heavy metals (lead, cadmium, arsenic, mercury). We welcome original research articles and comprehensive reviews investigating the detoxification potential, molecular mechanisms, in vitro and in vivo efficacy, and potential applications of these natural antioxidants in food safety, nutrition, and preventive medicine.

Prof. Dr. Shusheng Tang
Guest Editor

Dr. Xingyao Pei
Guest Editor Assistant

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