Role of Oxidative Stress in Eye Diseases
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 20 February 2026 | Viewed by 28
Special Issue Editor
Special Issue Information
Dear Colleagues,
Oxidative stress is recognized as a key factor in the pathophysiology of numerous eye diseases. The eye is particularly vulnerable to oxidative damage due to its high oxygen consumption, continuous exposure to light, and rich content of polyunsaturated fatty acids. Reactive oxygen species (ROS) disrupt cellular homeostasis, induce lipid peroxidation, and damage proteins and DNA, ultimately contributing to the onset and progression of various ocular disorders.
This Special Issue aims to examine the complex role of oxidative stress in the development and progression of eye diseases, including—but not limited to—age-related macular degeneration, diabetic retinopathy, glaucoma, cataracts, and uveitis. We welcome original research articles and comprehensive reviews that explore underlying molecular mechanisms, identify oxidative biomarkers, and assess the efficacy of antioxidants or redox-modulating therapies in promoting ocular health. We encourage the submission of papers that use in vitro, in vivo, and clinical models.
By compiling state-of-the-art research in this area, this Special Issue seeks to deepen our understanding of oxidative stress as a therapeutic target and foster the development of innovative strategies to prevent or mitigate vision loss related to oxidative damage.
Prof. Dr. Tatsuya Mimura
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- oxidative stress
- reactive oxygen species
- ocular disorders
- age-related macular degeneration
- retinopathy
- glaucoma
- cataracts
- uveitis
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
