Oxidative Stress in Hearing Loss—2nd Edition
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 70
Special Issue Editors
Interests: ear; outer hair cell; inner ear
Special Issues, Collections and Topics in MDPI journals
Interests: hair cells; auditory; ear; inner; neurosciences; otolaryngology; physiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Following the success of our first Special Issue on "Oxidative Stress in Hearing Loss," which attracted 10 high-quality manuscripts, we can announce Volume II of this important topic. Hearing loss remains a critical global health challenge, with oxidative stress playing a central role in cochlear damage.
Oxidative stress, caused by an imbalance between reactive oxygen species (ROS) production and elimination, is a key mechanism in inner ear injury, leading to sensorineural hearing loss (SNHL). The cochlea’s high metabolic activity makes it highly vulnerable to oxidative damage. This process contributes to age-related hearing loss (ARHL), noise-induced hearing loss (NIHL), and ototoxic drug-induced hearing loss.
Given the promising potential of antioxidants in hearing protection and restoration, this second Special Issue will expand on recent advances in the field. We invite original research articles, reviews, and clinical studies covering, but not limited to, the following topics:
- Molecular mechanisms of oxidative stress in hearing loss;
- Novel antioxidant therapies (e.g., small molecules, nanoparticles, gene therapy);
- Mitochondrial-targeted disease mechanism and cochlear protection;
- Biomarkers of oxidative damage in hearing disorders;
- Preclinical and clinical studies on antioxidant efficacy.
Dr. Lei Song
Prof. Dr. Joseph Santos-Sacchi
Guest Editors
Manuscript Submission Information
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Keywords
- ear
- outer hair cell
- inner ear
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