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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Agri-Food Wastes as Natural Source of Bioactive Antioxidants: Fourth Edition

edited by

Silvana Hrelia

Cristina Angeloni

and

Maria Cristina Barbalace

submission deadline 10 Jul 2026 | 11 articles | Viewed by 22116 | Submission Open

Keywords: agri-food by-products; agri-food waste; nutraceuticals; functional foods; cosmeceutical products; sustainable practices; bioactive compounds; health effects

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Heme Proteins and Signaling in Redox Biology

edited by

Brandon Reeder

submission deadline 10 Jul 2026 | 1 articles | Viewed by 1401 | Submission Open

Keywords: heme proteins; redox biology; globin; oxygen binding and sensing proteins

(This special issue belongs to the Section ROS, RNS and RSS)

Hydrophilic and Lipophilic Antioxidants in Foods and Food Processing

edited by

Volker Böhm

submission deadline 15 Jul 2026 | 2 articles | Viewed by 2845 | Submission Open

Keywords: antioxidant activity; antioxidant capacity; antioxidant mechanisms; carotenoids; polyphenols; vitamin C; vitamin E; impact of food processing

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Phytochemical Analysis and Evaluation of Antioxidant Properties in Medicinal Plants

edited by

Magdalena Jeszka-Skowron

Agnieszka Zgoła-Grześkowiak

Tomasz Grześkowiak

and

Robert Frankowski

submission deadline 20 Jul 2026 | 10 articles | Viewed by 31863 | Submission Open

Keywords: antioxidant activity; phytochemicals in plants; medicinal plants; extraction; in vivo analysis; in vitro analysis

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

The Interaction Between Gut Microbiota and Host Oxidative Stress

edited by

Jie Yin

submission deadline 20 Jul 2026 | 4 articles | Viewed by 12890 | Submission Open

Keywords: oxidative stress; antioxidants; gut microbiome; immunity

Antioxidants and Multifunction Photoprotection—2nd Edition

edited by

André Rolim Baby

and

Catarina Rosado

submission deadline 20 Jul 2026 | 1 articles | Viewed by 9299 | Submission Open

Keywords: natural and synthetic antioxidants; sunscreens; multifunctional products; safety and efficacy establishment; product technologies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Glutathione and Health: From Development to Disease

edited by

Ying Chen

and Vasilis K. Vasiliou

submission deadline 20 Jul 2026 | 3 articles | Viewed by 8749 | Submission Open

Keywords: glutathione; antioxidants; antioxidant enzymes; oxidative stress; redox biology; molecular biology; cellular biology; biochemistry; development; disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress Induced by Air Pollution, 3rd Edition

edited by

Yasuhiro Yoshida

submission deadline 20 Jul 2026 | 3 articles | Viewed by 3897 | Submission Open

Keywords: particulate matter; air pollution; oxidative stress; reactive oxygen species; inflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Lipid Peroxidation, Vegetable Oil Oxidation, and the Role of Plant Extracts in Enhancing Oxidative Stability

edited by

Daniele Sanna

and

Angela Fadda

submission deadline 20 Jul 2026 | 2 articles | Viewed by 2003 | Submission Open

Keywords: oil oxidative stability; natural antioxidants; lipid peroxidation; surfactants; encapsulation

(This special issue belongs to the Section Aberrant Oxidation of Biomolecules)

Applications and Health Benefits of Novel Antioxidant Biomaterials—2nd Edition

edited by

Washington Luiz Esteves Magalhães

and Tielidy Lima

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1992 | Submission Open

Keywords: antioxidant biomaterials; tissue regeneration; biocompatibility; controlled release; premature aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Regulation in Algae

edited by

Kim Gwang Hoon

submission deadline 20 Jul 2026 | Viewed by 354 | Submission Open

Keywords: algae; reactive oxygen species; redox regulation; stress responses; NADPH oxidases; antioxidants; redox-sensitive transcription factors

(This special issue belongs to the Section ROS, RNS and RSS)

The Role of Oxidative Stress in Age-Related and Degenerative Eye Diseases

edited by

Ting Zhang

submission deadline 30 Jul 2026 | 6 articles | Viewed by 8323 | Submission Open

Keywords: oxidative stress; age-related macular degeneration; retinal degeneration; reactive oxygen species; redox signaling; mitochondrial dysfunction; antioxidant therapy; artificial intelligence; multi-omics; biomarkers; vision science

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Selected Papers from the 2nd International Electronic Conference on Antioxidants (IECAN2025)

edited by

Alessandra Napolitano

and

Mario Allegra

submission deadline 31 Jul 2026 | 4 articles | Viewed by 23662 | Submission Open

Keywords: obesity; cardiovascular diseases; chronic disease; dietary prevention; antioxidants intake; gut microbiome; natural and synthetic antioxidants; antioxidant enzyme systems; antioxidant extraction

Green Extraction of Antioxidant from Natural Source

edited by

Jolanta Flieger

submission deadline 31 Jul 2026 | 8 articles | Viewed by 20405 | Submission Open

Keywords: green extraction techniques ; supercritical fluid extraction ; ionic liquid (IL)-based extraction; microwave-assisted extraction; antioxidants; plants; cosmetic formulation

Antioxidants as Adjuvants for Inflammatory Bowel Disease Treatment

edited by

Marcello Chieppa

and

Angelo Santino

submission deadline 31 Jul 2026 | 7 articles | Viewed by 18669 | Submission Open

Keywords: IBD; antioxidant; gut barrier; inflammation; natural compounds; microbiome; colon cancer; adjuvant; nutritional bioactive products; polyphenols

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Exploring New Frontiers in Oxidative Stress and Antioxidant Research: From Model Organisms to Human Disease

edited by

Marcello Ziosi

and

Gaetano Santulli

submission deadline 31 Jul 2026 | 6 articles | Viewed by 16419 | Submission Open

Keywords: oxidative stress; antioxidant therapeutics; cell death and survival pathways; cellular signaling networks; gene regulation and expression

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Compounds and Health Benefits of Mediterranean Functional Food

edited by

Stefania D'Angelo

submission deadline 31 Jul 2026 | 7 articles | Viewed by 15643 | Submission Open

Keywords: antioxidants; anti-inflammatory; anti-obesity; functional food; human health; Mediterranean diet; nutraceuticals; nutrition; oxidative stress; phytochemicals; polyphenols

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Plant Materials and Their Antioxidant Potential, 3rd Edition

edited by

Elisabeta Irina Geana

and

Ovidiu Tita

submission deadline 31 Jul 2026 | 6 articles | Viewed by 6632 | Submission Open

Keywords: antiseptic; antioxidant; volatile oil; compounds; fruits and vegetables; medicinal plants; agri-food industry; food ingredients; functional foods; nutraceuticals; food supplements; pharmaceutical products; antioxidant activity; oxidative stress; aging; anti-inflammatory activity; sustainable recovery; circular bioeconomy

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Bioactive Antioxidants: Structural Characterization, Synthetic Pathways, and Clinical Applications

edited by

Jolanta Flieger

submission deadline 31 Jul 2026 | 4 articles | Viewed by 5267 | Submission Open

Keywords: bioactive antioxidants; therapeutic potential; synthetic strategies; structural characterization

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Natural Antioxidants in Counteracting Mycotoxin and Heavy Metal Toxicity

edited by

Shusheng Tang

and Xingyao Pei

submission deadline 31 Jul 2026 | 3 articles | Viewed by 4669 | Submission Open

Keywords: natural antioxidants; mycotoxins; heavy metal; detoxification

Olive Antioxidants: Extraction, Biological Activity and Practical Applications—3rd Edition

edited by

Juan Fernández-Bolaños

and

Alejandra Bermudez-Oria

submission deadline 31 Jul 2026 | 2 articles | Viewed by 4642 | Submission Open

Keywords: antioxidant effect; olive oil; olive by-products; olive leaves; polyphenols; carotenoids; polysaccharide–polyphenol complexes; vitamin E; health; Mediterranean diet

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Oxidative Stress and Mitochondrial Dysfunction in Metabolic Disorders

edited by

Pablo M. García-Rovés

Steen Larsen

and Hugo J Alves-Figueiredo

submission deadline 31 Jul 2026 | 2 articles | Viewed by 4626 | Submission Open

Keywords: metabolic diseases; oxidative stress; mitochondrial dysfunction; antioxidant therapies; lifestyle interventions; gene therapies; mitochondrial transfer therapies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Metabolic Dysfunction and Oxidative Stress

edited by

Vinood B. Patel

and

Mohammed Gulrez Zariwala

submission deadline 31 Jul 2026 | 2 articles | Viewed by 4494 | Submission Open

Keywords: iron; mitochondria; oxidative stress; inflammation; metabolism; free radicals

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants and Antioxidant Mechanisms in the Prevention and Treatment of Infectious Diseases

edited by

Gabriele Carullo

Maria Dichiara

Valeria Tudino

and Sara Rossi

submission deadline 31 Jul 2026 | 2 articles | Viewed by 4071 | Submission Open

Keywords: antioxidants; infectious diseases; quorum sensing; inflammation; natural and synthetic antioxidants; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Signaling in Chronic Diseases

edited by

Emma Borrelli

submission deadline 31 Jul 2026 | 2 articles | Viewed by 3533 | Submission Open

Keywords: redox signaling; chronic oxidative diseases; redox modulator; oxidative stress; antioxidant; redox homeostasis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Bone Metabolic Diseases

edited by Zhongbo Liu

submission deadline 31 Jul 2026 | 1 articles | Viewed by 3182 | Submission Open

Keywords: oxidative stress; bone metabolic diseases; osteoporosis; mitochondrial dysfunction; antioxidants; reactive species; osteoblast/osteoclast/osteocyte; Nrf2

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Male Reproductive Health—2nd Edition

edited by

Robert John Aitken

and

Joel R. Drevet

submission deadline 31 Jul 2026 | 3 articles | Viewed by 2747 | Submission Open

Keywords: oxidative stress; antioxidant therapy; male reproductive health; male fertility; erectile dysfunction; prostatic disease; male ageing

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Lipotoxicity in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Its Therapeutic Control

edited by

Isao Ishii

submission deadline 31 Jul 2026 | 1 articles | Viewed by 2702 | Submission Open

Keywords: metabolic dysfunction–associated steatotic liver disease (MASLD); metabolic dysfunction–associated steatohepatitis (MASH); fatty liver; lipotoxicity; ferroptosis; inflammation; fibrosis; Fenton reaction; thyroid hormone receptor-beta (THR-β) agonist; peroxisome proliferator-activated receptor (PPAR) agonist; farnesoid X receptor (FXR) agonist

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Role of Dietary Antioxidants in Alleviating Oxidative Stress and Inflammation for Enhanced Immunity in Animals

edited by Yanka D. Karamalakova and

Jie Yin

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1849 | Submission Open

Keywords: antioxidants; antioxidant feeding; insect meal; growth performance; digestible energy; nutrient digestibility; blood biochemistry; oxidative stress (OS); lipid peroxidation (MDA); ROS/RNS; superoxide dismutase (SOD); catalase (CAT); glutathione (GSH); glutathione peroxidase (GPx); inflammation markers; total antioxidant capacity (TAC); meat, milk, eggs quality

Antioxidants in Cosmetics

edited by

Fotini Lamari

Vassiliki Magafa

and

Sophia Hatziantoniou

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1793 | Submission Open

Keywords: cosmetics; herbal extracts; natural products; peptides; synthesis; isolation; oxidative stress; emulsions; nanoparticles; fibroblasts; ageing

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Oxidative Stress Across Kingdoms in the Gut: Host Immunity, Microbiota, Oxidized Foods, and Neurotransmitter Interactions

edited by Alex Rodriguez-Palacios

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1785 | Submission Open

Keywords: oxidative stress; gut; microbiota; ROS; metabolic

Oxidative Stress and Airway Diseases

edited by Miguel Santibáñez-Margüello

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1580 | Submission Open

Keywords: oxidative stress; asthma; chronic obstructive pulmonary disease (COPD); particulate matter oxidative potential (PM-OP)

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Delivery Systems for Natural Antioxidant Compounds

edited by

Antonio Vassallo

Lucía Martín-Banderas

and

Immacolata Faraone

submission deadline 31 Jul 2026 | 1 articles | Viewed by 781 | Submission Open

Keywords: natural antioxidants; delivery systems; nanoencapsulation; liposomes; emulsions; spray drying; controlled release; bioavailability enhancement; polymeric carriers; lipid-based systems; supramolecular assemblies; antioxidant protection; functional applications; shelf-life extension

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Phytochemical Profile, Antioxidant and Cytotoxic Activities of Plant Essential Oils

edited by

Natale Badalamenti

and

Gianfranco Fontana

submission deadline 31 Jul 2026 | 1 articles | Viewed by 472 | Submission Open

Keywords: essential oils; antioxidant properties; anti-inflammatory activity; phytochemistry; antiproliferative evaluation

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Oxidative Stress in Blood and Vascular Cells and Vascular Pathophysiology

edited by

Anna Pieniazek

submission deadline 31 Jul 2026 | Viewed by 293 | Submission Open

Keywords: blood; vascular cells; cellular stressors; redox homeostasis; oxidative stress; cell death; redox modulators

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Effects of Nutraceutical

edited by

Adriana Elena Bulboaca

submission deadline 31 Jul 2026 | Viewed by 237 | Submission Open

Keywords: oxidative stress; reactive oxygen species; antioxidants; nutraceutical; polyphenols; redox balance

Inflammatory Mediators and Oxidative Balance in Vascular Pathophysiology

edited by

Yun Jung Lee

submission deadline 31 Jul 2026 | Viewed by 209 | Submission Open

Keywords: inflammatory mediators; oxidative stress; vascular pathophysiology; endothelial dysfunction; antioxidants; redox signaling; oriental medicine; herbal medicine; network pharmacology; cardiovascular disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Biomarkers in Veterinary Medicine

edited by

Zoe S. Polizopoulou

and

Serafeim Chaintoutis

submission deadline 1 Aug 2026 | Viewed by 403 | Submission Open

Keywords: oxidative damage; redox homeostasis; reactive oxygen species; antioxidant systems; oxidative stress biomarkers

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Therapeutic Approaches in Lung Diseases

edited by Ru-Jeng Teng

submission deadline 10 Aug 2026 | 1 articles | Viewed by 2685 | Submission Open

Keywords: oxidative stress; antioxidant therapy; therapeutic strategies; patient care

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Role of Reactive Oxygen Species (ROS) in Tumor Microenvironment Modulation

edited by

Antonis Giakountis

and

Dimitrios Kouretas

submission deadline 20 Aug 2026 | 5 articles | Viewed by 11731 | Submission Open

Keywords: reactive oxygen species; tumor microenvironment; stroma cells; functional genomics; spatial transcriptomics; single-cell sequencing; RNA-seq; cancer; diagnosis and prognosis; biomarkers

Super Oxide Dismutase (SOD) Isoenzymes and Reactive Oxygen Species (ROS) in Immuno-Pathophysiology

edited by Giuseppina Ruggiero and

Paolo Mondola

submission deadline 20 Aug 2026 | 3 articles | Viewed by 4871 | Submission Open

Keywords: superoxide dismutase (SOD) isoenzymes; superoxide dismutase (SOD)1; cell signalling; cell metabolism; cell functions; cellular stress; disease pathogenesis

Advances in Plant Redox Biology Research

edited by Yurong Xie and Ming Chang

submission deadline 20 Aug 2026 | 3 articles | Viewed by 2972 | Submission Open

Keywords: plant redox biology; reactive oxygen species; reactive nitrogen species; plant development; environmental stress; abiotic/biotic stresses; host–microbe interactions

(This special issue belongs to the Section ROS, RNS and RSS)

Methodologies for Improving Antioxidant Properties and Absorption, 2nd Edition

edited by

Daniela Tofani

submission deadline 20 Aug 2026 | Viewed by 454 | Submission Open

Keywords: bioavailability; targeted absorption; delivery systems; antioxidant structural modification; structure–activity relationship

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Oxidative Stress in Diabetic Retinopathy and Other Retinal Diseases

edited by

Kwon-Soo Ha

submission deadline 20 Aug 2026 | Viewed by 212 | Submission Open

Keywords: vascular dysfunction; oxidative stress; mitochondrial dynamics; neurovascular dysfunction; diabetic retinopathy; age-related macular degeneration; retinal vein occlusion

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Carotenoids in Health and Disease

edited by Kazutoshi Shindo

submission deadline 30 Aug 2026 | 5 articles | Viewed by 26470 | Submission Open

Keywords: antioxidant activities of carotenoids; analytical chemistry on carotenoids; reactive oxygen species (ROS) and disease; production of carotenoids

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Novel Strategies for Oxidative Stress Management: Dietary Interventions for Liver and Gut Health

edited by

Antonio Cilla

and

Mussa Makran

submission deadline 30 Aug 2026 | 3 articles | Viewed by 11518 | Submission Open

Keywords: antioxidant compounds; phytochemicals; dietary interventions; hepatic disease; intestinal disease; redox homeostasis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Systems in Plants

edited by

Francisco Espinosa Borreguero

, Ilda Jesús Casimiro Felicio and

Inmaculada Garrido Carballo

submission deadline 30 Aug 2026 | 3 articles | Viewed by 4642 | Submission Open

Keywords: enzymatic antioxidants; non-enzymatic antioxidants; nitro-oxidative stress; reactive oxygen species; reactive nitrogen species; ROS and RNS signaling

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Phenolic Compounds from Novel Natural Sources and Fermented Foods

edited by

Harris Papapostolou

and

Maria Alexandri

submission deadline 30 Aug 2026 | Viewed by 234 | Submission Open

Keywords: phenolic compounds; plant-derived antioxidants; fermentation; foods

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Oxidative Stress and NRF2 in Health and Disease—2nd Edition

edited by

Lidija Milković

submission deadline 31 Aug 2026 | 16 articles | Viewed by 44794 | Submission Open

Keywords: oxidative stress; redox signaling; NRF2 and its regulation; redox-modifying therapeutic approach; omics approach; physiology; non-communicable diseases; metabolism; aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Role of Antioxidants in Enhancing Training Adaptation, Exercise Performance, and Post-exercise Recovery

edited by