Antioxidant Effects of Natural Compounds on Cell Metabolism
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Natural and Synthetic Antioxidants".
Deadline for manuscript submissions: 12 January 2026 | Viewed by 1618
Special Issue Editors
Interests: antioxidants; oxidative stress; red blood cells; oxygen; metabolic pathways; flavonoids; lipid peroxidation; hemoglobin; erythrocyte metabolism; blood; free radicals; free radical scavengers
Special Issues, Collections and Topics in MDPI journals
Interests: blood; red blood cells; hemoglobin; erythrocyte membranes; oxygen; oxidative stress; antioxidant activity; natural compounds; lipid peroxidation; free radicals; free radical scavengers; adenosine triphosphate; erythrocyte metabolism
Special Issue Information
Dear Colleagues,
Organisms possess countless metabolic and biosynthetic capacities that constitute a rich source of new opportunities to discover functions and pathways that are still unknown and for which the identification of all enzymatic functions in a pathway is essential. Maintaining the proper functioning of the thousands of biochemical reactions that take place inside cells that can be exposed to various natural stressors or that result from environmental pollution is the key to safeguarding life itself.
Oxidative stress can be caused by an imbalance between the cell’s antioxidant defenses and free radical generation. For this reason, it is important to improve cellular antioxidant systems that are given by a combination of molecules, complexes, and biochemical processes that protect the cell from oxidative insults.
Cellular metabolism and its dysregulation plays a key role in the biochemistry of the onset of many diseases, such as cancer, metabolic syndrome, diabetes, cardiovascular diseases, and neurodegeneration.
In light of the historical moment following the COVID-19 pandemic, in which the attention of the entire scientific community was focused on the development and therapeutic potential of new molecules, this Special Issue aims to bring together new scientific research aimed at outlining advances in the discovery of new enzyme functions and metabolic pathways, studying the potential effects of natural compounds on cell metabolism and human health.
The antioxidant properties of natural compounds are emerging as effective agents against many chronic and progressive human diseases related to aging by reducing oxidative stress and simultaneously suppressing free radicals and the formation of reactive oxygen species in various metabolic reactions at the cellular level.
In this context, the multiplicity of bioactive molecules that presents in nature, which is associated with a potential metabolic effect, represents an excellent option to improve immune response against disease and can be a valid alternative to synthetic drugs. Knowledge of the mechanisms involving the alteration of energy metabolism, the overproduction of reactive oxygen species, and the imbalance between cell proliferation and death represent useful tools with which to create new and more effective therapeutic approaches to ensure a better quality of life. Therefore, the study of potential natural mediators of cellular metabolism has become an interesting research topic.
In this Special Issue, the main focus will be on the involvement of natural compounds on cell metabolism under physiological conditions and the potential antioxidant activities against disease progression. It is possible to improve this new field with original research articles and/or reviews.
Prof. Dr. Ester Tellone
Dr. Annamaria Russo
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antioxidants
- metabolic pathways
- dietary intake
- blood cells
- bioactive compounds
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