Diabetic Retinopathy and Oxidative Stress: Molecular Mechanisms, Diagnostic Strategies, and Advances in Antioxidant Therapies
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 1369
Special Issue Editors
Interests: biochemistry; genetics and molecular biology medicine pharmacology; toxicology; pharmaceutics; immunology; microbiology; agricultural and biological sciences; engineering; neuroscience; chemistry; physics and astronomy; environmental science; oxidative stress; diabetic retinopathy; antioxidants; natural products; polyphenols
Special Issues, Collections and Topics in MDPI journals
Interests: nutrition; longevity; aging; oxidative stress and exercise
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Diabetic retinopathy is a progressive asymptomatic neurovascular complication of diabetes that results in irreversible retinal damage. The rising prevalence of diabetes has established it as the leading cause of preventable blindness, particularly among the working-age population worldwide. Diabetic retinopathy exhibits a complex etiology, which complicates the understanding of how diabetes induces this pathology. However, there is a strong consensus on the pivotal role of oxidative stress, triggered by disrupted glycemic homeostasis, in the development and progression of diabetic retinopathy. Current treatments primarily address diabetic retinopathy in its advanced stages, when vision has already been substantially compromised. Therefore, early diagnosis and clinical interventions are essential to prevent disease progression and avoid irreversible retinal damage.
This Special Issue will explore the role of oxidative stress in the pathogenesis of diabetic retinopathy, with a focus on the molecular pathways involved in disease onset and progression, innovative diagnostic methods to improve sensitivity in disease staging, the identification of clinically relevant biomarkers, and the development of novel antioxidant therapeutic strategies. We welcome authors to contribute original research articles, clinical trials, traditional reviews, and systematic reviews to advance our understanding of the disease and foster progress in its diagnosis and treatment.
We look forward to your contribution.
Dr. Ángel Luis Ortega
Dr. Juan Gambini
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- diabetic retinopathy
- natural antioxidants
- oxidative stress
- epigenetic mechanisms
- biomarkers
- diagnostic methods
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