Oxidative Stress and Airway Diseases
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 95
Special Issue Editor
2. CIBER of Respiratory Diseases (CIBERES), Instituto de Salud Carlos III, Madrid, Spain
Interests: respiratory system; public; environmental and occupational health
Special Issue Information
Dear Colleagues,
Oxidative stress refers to an imbalance between reactive oxygen species (ROS) and the endogenous antioxidant capacity, which can lead to the oxidation of lipids and proteins, as well as damage to DNA and RNA. This contributes to enhanced airway and systemic inflammatory responses and plays a key role in the development and clinical course of airway diseases.
This disruption in redox homeostasis may arise as a consequence of environmental airborne exposure to particulate matter (PM) with high oxidative potential; from impaired endogenous antioxidant mechanisms; or as a result of the intrinsic pathophysiological processes of the airway disease itself. As an example, chronic inflammation in asthma is mediated by the activation of granulocytes, with an invasion of the bronchial mucosa. In addition to the ROS incorporated by the airborne PM, activated macrophages, neutrophils, and eosinophils are able to release ROS. Therefore, it is not clear whether, in terms of ROS, the contribution of PM inhalation is greater than that of the inflammatory cells themselves.
This Special Issue welcomes the submission of original research articles, reviews, meta-analyses, and clinical trial results exploring any aspect of oxidative stress in the physiopathogenesis of airway diseases, as well as antioxidant-based therapeutic interventions.
We look forward to your contributions.
Dr. Miguel Santibáñez-Margüello
Guest Editor
Manuscript Submission Information
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Keywords
- oxidative stress
- asthma
- chronic obstructive pulmonary disease (COPD)
- particulate matter oxidative potential (PM-OP)
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