Role of Antioxidants in the Interplay Between Gut Microbiota and Cardiovascular Disease
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 1972
Special Issue Editors
Interests: immunology; microbiology; nutrition; mucosal immunity; nutraceuticals; polyphenols; pathology; obesity; cytokines
Special Issues, Collections and Topics in MDPI journals
2. Microbiology and Virology Unit, Policlinico University, Rome, Italy
Interests: human microbiota; clinical microbiology; infectious diseases; host-microbe interactions; anti-microbial resistance; probiotics; microbial by-products
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The gut microbiota plays an important role in maintaining homeostasis and thus contributing to the maintenance of human health. However, factors such as gender, age, and lifestyle (e.g., physical activity, diet) influence the composition and function of the gut microbiota, leading to several diseases (e.g., cardiovascular disease) and immune-related disorders. Physical activity changes the gut microbiota's composition, increasing the bacteria that produce short-chain fatty acids. These metabolites exert anti-inflammatory and immunomodulatory effects that can improve intestinal barrier function, reduce endotoxemia, and enhance cardiovascular function. This can be facilitated through a high dietary intake of natural products with antioxidant properties. Similarly, alterations in microbial diversity and richness are associated with low-grade systemic inflammation, endothelial dysfunction, and an increased risk of cardiovascular disease, particularly in the elderly population. In this Special Issue, we will explore the relationship between the gut microbiota, physical activity, cardiovascular diseases, diet, and the effects of endogenous and exogenous antioxidants in reducing oxidative stress.
Dr. Thea Magrone
Prof. Dr. Luigi Santacroce
Guest Editors
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Keywords
- antioxidants
- cardiovascular diseases
- diet
- gut microbiota
- physical activity
- signalling pathways
- senescence
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