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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mitochondrial Oxidative Stress in Aging and Disease—2nd Edition

edited by

Angela Maria Serena Lezza

and

Vito Pesce

submission deadline 15 Jan 2026 | 7 articles | Viewed by 20933 | Submission Open

Keywords: mitochondrial oxidative stress in aging; mitochondrial oxidative stress in age-related or metabolic diseases; mitochondrial signaling via ROS in diseases; mitochondrial oxidative stress and genomic instability; mitochondrial oxidative stress and inflammation; antioxidants as novel therapeutic approaches; mitochondrial pathologies; aging; mitochondrial

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants and Multifunction Photoprotection—2nd Edition

edited by

André Rolim Baby

and

Catarina Rosado

submission deadline 20 Jan 2026 | 1 articles | Viewed by 2731 | Submission Open

Keywords: natural and synthetic antioxidants; sunscreens; multifunctional products; safety and efficacy establishment; product technologies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Exploring the Role of Polyphenols in Oxidative Stress and Cellular Protection

edited by

Lucia Gimeno-Mallench

submission deadline 20 Jan 2026 | 1 articles | Viewed by 2438 | Submission Open

Keywords: polyphenol; oxidative stress; cellular signaling; metabolic pathways

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Advances in Peroxiredoxin Biology

edited by Mikael Molin and Cecilia Picazo

submission deadline 23 Jan 2026 | 1 articles | Viewed by 811 | Submission Open

Keywords: oxidative stress; aging; age-related diseases; H2O2 signaling; redox regulation

(This special issue belongs to the Section Antioxidant Enzyme Systems)

Interplay Between Gut Microbiota and Oxidative Stress

edited by

Sunmin Park

submission deadline 25 Jan 2026 | Viewed by 363 | Submission Open

Keywords: gut microbiota; redox; human health; gut homeostasis

Redox Balance and Autophagy in Neuroinflammation

edited by

Anna Colell

and

Vicente Roca-Agujetas

submission deadline 26 Jan 2026 | Viewed by 304 | Submission Open

Keywords: oxidative stress/oxidative damage ; reactive oxygen species (ROS) ; redox homeostasis ; autophagy ; lysosomal clearance ; proteinopathies ; neuroinflammation ; neurological disorders ; cellular homeostasis ; neuroprotection

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Diabetic Retinopathy

edited by Tatsuya Mimura

submission deadline 30 Jan 2026 | 1 articles | Viewed by 2752 | Submission Open

Keywords: diabetic retinopaty; oxidative stress; antioxidants; inflammation; environmental factor

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Environmental Risk Factors and Oxidative Stress in the Retina

edited by

Adrian Gericke

submission deadline 30 Jan 2026 | Viewed by 336 | Submission Open

Keywords: environment; pollution; oxidative stress; retina

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Signaling in Chronic Diseases

edited by

Emma Borrelli

submission deadline 30 Jan 2026 | Viewed by 335 | Submission Open

Keywords: redox signaling; chronic oxidative diseases; redox modulator; oxidative stress; antioxidant; redox homeostasis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Regulation by One-Electron Transferring Flavoproteins: Catalysis and Metabolism

edited by

Daisuke Seo

and

Narimantas K. Cenas

submission deadline 30 Jan 2026 | Viewed by 142 | Submission Open

Keywords: flavin mononucleotide (FMN); flavin adenine dinucleotide (FAD); single-electron transfer; free radicals; reactive oxygen species (ROS); mitochondrial respiration; photosynthesis; nitrogen fixation; electron flux bifurcation; immune response; semiquinone

(This special issue belongs to the Section Antioxidant Enzyme Systems)

Redox Regulation in Animal Reproduction

edited by Zhongliang Jiang

submission deadline 31 Jan 2026 | 11 articles | Viewed by 39729 | Submission Open

Keywords: spermatogenesis; follicular atresia; oocyte maturation; granulosa cells; hormone regulation; autophagy; apoptosis; oxidative stress; signaling regulation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Natural Antioxidants and Aquatic Animal Health—2nd Edition

edited by

Rui Jia

submission deadline 31 Jan 2026 | 10 articles | Viewed by 12598 | Submission Open

Keywords: natural antioxidants; oxidative stress; medicinal plants; aquatic animals; feed additives

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants Benefits in Aquaculture—3rd Edition

edited by

Ángel Isidro Cámpa-Córdova

submission deadline 31 Jan 2026 | 4 articles | Viewed by 5221 | Submission Open

Keywords: aquaculture; invertebrates; vertebrates; oxidative stress; antioxidant response; antioxidant enzymes; antioxidant gene expression; antioxidant products

Diabetic Retinopathy and Oxidative Stress: Molecular Mechanisms, Diagnostic Strategies, and Advances in Antioxidant Therapies

edited by

Ángel Luis Ortega

and

Juan Gambini

submission deadline 31 Jan 2026 | 2 articles | Viewed by 4563 | Submission Open

Keywords: diabetic retinopathy; natural antioxidants; oxidative stress; epigenetic mechanisms; biomarkers; diagnostic methods

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Effect of Nutritional Intervention and Diet on Oxidative Stress and Human Diseases

edited by

Josep A. Tur

, Cristina Bouzas and

Margalida Monserrat-Mesquida

submission deadline 31 Jan 2026 | 2 articles | Viewed by 4023 | Submission Open

Keywords: nutrition; diet; oxidative stress; inflammation; human chronic diseases; supplements; cardiovascular diseases; diabetes; obesity

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Innovations in Drug Delivery Systems for Antioxidant-Based Therapeutic Agents

edited by

Judit Váradi

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3764 | Submission Open

Keywords: antioxidant; bioaccessibility/bioavailability; stability; controlled release; drug delivery system; nanoparticles; nano-carriers

Role of Antioxidants in the Interplay Between Gut Microbiota and Cardiovascular Disease

edited by

Thea Magrone

and

Luigi Santacroce

submission deadline 31 Jan 2026 | 1 articles | Viewed by 2271 | Submission Open

Keywords: antioxidants; cardiovascular diseases; diet; gut microbiota; physical activity; signalling pathways; senescence

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Plant Materials and Their Antioxidant Potential, 3rd Edition

edited by

Elisabeta Irina Geana

and

Ovidiu Tita

submission deadline 31 Jan 2026 | 3 articles | Viewed by 1940 | Submission Open

Keywords: antiseptic; antioxidant; volatile oil; compounds; fruits and vegetables; medicinal plants; agri-food industry; food ingredients; functional foods; nutraceuticals; food supplements; pharmaceutical products; antioxidant activity; oxidative stress; aging; anti-inflammatory activity; sustainable recovery; circular bioeconomy

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Antioxidants from the Perspective of Environmental Physiology and Pathology

edited by

Gianfranco Santovito

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1834 | Submission Open

Keywords: antioxidants; environmental stress; pollutants; health; oxidative stress

Oxidative Stress and Human Reproduction

edited by Sofoklis Stavros and Despoina Mavrogianni

submission deadline 31 Jan 2026 | Viewed by 1774 | Submission Open

Keywords: reproduction; oxidative stress; ROS; pregnancy

Natural Antioxidants in Counteracting Mycotoxin and Heavy Metal Toxicity

edited by

Shusheng Tang

and Xingyao Pei

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1673 | Submission Open

Keywords: natural antioxidants; mycotoxins; heavy metal; detoxification

Oxidative Stress and Inflammation in Heart Failure

edited by Camilla Hage

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1190 | Submission Open

Keywords: heart failure; oxidative stress; HFrEF; HFpEF; reactive oxygen species; nitric oxide; cardiomyocytes; cardiomyopathies; cardiac dysfunction

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants from the Sea and Their Application

edited by

Daniela Giordano

and

Chiara Lauritano

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1103 | Submission Open

Keywords: marine natural products; marine enzymes; marine nutraceuticals; marine cosmeceuticals; food supplements; antioxidant mechanisms of action; structure– function relationship; antioxidant capacity; biotechnological application; biotechnological production

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Redox Regulation of Membrane Transporters: Mechanisms and Implications

edited by

Fátima Martel

submission deadline 31 Jan 2026 | 1 articles | Viewed by 593 | Submission Open

Keywords: antioxidants; membrane transport; pathologies; modulation; redox potencial

Antioxidant Potential of Phytotherapy in Cardiovascular Diseases

edited by

Valentina Oana Buda

submission deadline 31 Jan 2026 | Viewed by 241 | Submission Open

Keywords: phytotherapy; cardiovascular diseases; oxidative stress; antioxidants; medicinal plants; polyphenols; endothelial function; redox balance; natural compounds; plant-derived bioactives

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Lung Diseases: Pathogenic Mechanisms and Therapeutic Implications

edited by

Esteban C. Gabazza

submission deadline 31 Jan 2026 | Viewed by 212 | Submission Open

Keywords: COPD; lung cancer; pulmonary fibrosis; oxidative stress; antioxidant therapies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Lipoproteins and Redox Imbalance in Health and Disease: Mechanisms and Therapeutic Opportunities

edited by

Chiara Pavanello

and Alice Ossoli

submission deadline 31 Jan 2026 | Viewed by 166 | Submission Open

Keywords: lipoproteins; redox; lipid metabolism; oxidative stress; inflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Airway Diseases

edited by Miguel Santibáñez-Margüello

submission deadline 31 Jan 2026 | Viewed by 155 | Submission Open

Keywords: oxidative stress; asthma; chronic obstructive pulmonary disease (COPD); particulate matter oxidative potential (PM-OP)

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Role of Oxidative Stress in Vascular Disease Associated with Diabetes, 2nd Edition

edited by

Cristina M. Sena

submission deadline 10 Feb 2026 | Viewed by 222 | Submission Open

Keywords: obesity; diabetes; vascular dysfunction; oxidative stress; inflammation; insulin resistance; hyperglycemia; pancreas; beta cells

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Potential of the Mediterranean and Ketogenic Diets

edited by Elisabetta Camajani

submission deadline 10 Feb 2026 | Viewed by 188 | Submission Open

Keywords: Mediterranean diet; ketogenic diet; antioxidants; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Radioprotective Effects of Antioxidants

edited by

Ruth Edge

Homer S. Black

and

George Truscott

submission deadline 20 Feb 2026 | 6 articles | Viewed by 29213 | Submission Open

Keywords: radiation protection; ionizing radiation; photoprotection; ultraviolet (UV); vitamins; phytochemicals; sunscreens

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Brain Function—2nd Edition

edited by

Waldo Cerpa

submission deadline 20 Feb 2026 | 6 articles | Viewed by 22803 | Submission Open

Keywords: pathophysiological brain regulation; brain function; oxidative stress; brain damage; neurodegeneration; cellular signaling; neurotoxicity; excitotoxicity; synaptic transmission; cognitive function

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Properties in Novel Feed Ingredients for Fish

edited by

Inês Guerreiro

submission deadline 20 Feb 2026 | 5 articles | Viewed by 13355 | Submission Open

Keywords: aquafeeds; fish; oxidative status; aquaculture; antioxidant; insect meal

Antioxidants and Age-Related Changes in Skeletal Muscle and Vascular Health

edited by

Thiago Silveira Álvares

submission deadline 20 Feb 2026 | 2 articles | Viewed by 7766 | Submission Open

Keywords: phytochemicals; phenolic compounds; antioxidant supplementation; bioactivity; oxidative stress; reactive oxygen species; nitric oxide; endothelial function; microvascular reactivity; muscle oxygenation; muscle quality; fatigue resistance; sarcopenia; aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant and Anti-Inflammatory Components of the Diet

edited by

Rosita Gabbianelli

submission deadline 20 Feb 2026 | 3 articles | Viewed by 7176 | Submission Open

Keywords: plant-based foods; food antioxidants; food anti-inflammatory compounds; nutrigenomics

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Reactive Oxygen Species Signalling and Oxidative Stress in Fish

edited by Daniela Vallone and

Nicholas S. Foulkes

submission deadline 20 Feb 2026 | 4 articles | Viewed by 6544 | Submission Open

Keywords: ROS; toxicology; fish; zebrafish; metabolism; immunity; cell signalling

Oxidative Stress and Antioxidant Response in Insects

edited by

José Eduardo Serrão

submission deadline 20 Feb 2026 | 3 articles | Viewed by 6338 | Submission Open

Keywords: antioxidant enzymes; invertebrates; oxidative stress; pest control; pollinators; ROS; wild animals

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Modulation of Gut Microbiota and Oxidative Stress to Counteract or Prevent Human Disease

edited by

Simone Carradori

Annalisa Chiavaroli

Alessandra Ammazzalorso

and

Marialucia Gallorini

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3160 | Submission Open

Keywords: medicinal chemistry; enzyme modulators; neurodegenerative disorders; microbiota; gut– brain axis; inflammation; probiotic metabolomics; prebiotics; postbiotics; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Role of Oxidative Stress in Eye Diseases

edited by

Tatsuya Mimura

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2442 | Submission Open

Keywords: oxidative stress; reactive oxygen species; ocular disorders; age-related macular degeneration; retinopathy; glaucoma; cataracts; uveitis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Women’s Special Issue Series: Antioxidants in Human Health—2nd Edition

edited by

Simone Van Breda

and

Ruth Edge

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1633 | Submission Open

Keywords: oxidative stress; reactive oxygen species (ROS); antioxidants; vitamins; phytochemicals; molecular mechanisms; non-communicable diseases; human health; aging; clinical and public health applications

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Regulation of Immune and Inflammatory Responses

edited by

Yasuhiro Yoshida

submission deadline 25 Feb 2026 | 3 articles | Viewed by 3284 | Submission Open

Keywords: immune system; inflammatory responses; cytokines; immune cells; autoimmune disorders; chronic inflammation; and infections

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

ROS Levels and Thioredoxin Reductases

edited by

Jianqiang Xu

and Shui Guan

submission deadline 27 Feb 2026 | Viewed by 160 | Submission Open

Keywords: thioredoxin reductase; oxidative stress; antioxidants; bioactive materials; ferroptosis; disulfidptosis; necroptosis; apoptosis; autophagy; inflammation; diagnosis marker; oxidative stress; disulfide stress; redox regulation; nanomedicine

(This special issue belongs to the Section ROS, RNS and RSS)

Oxidative Stress in the Newborn

edited by Ru-Jeng Teng

submission deadline 28 Feb 2026 | 11 articles | Viewed by 27219 | Submission Open

Keywords: newborn; neonatal diseases; oxidative stress; reactive oxygen species; antioxidant therapy

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Human Diseases—4th Edition

edited by

Soliman Khatib

submission deadline 28 Feb 2026 | 5 articles | Viewed by 11594 | Submission Open

Keywords: oxidative stress; ROS/RNS; human diseases; antioxidants; OS biomarkers

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

From Waste to Health: Upcycling Agrifood By-Products into Functional Antioxidant-Rich Ingredients and Products

edited by

Ítala Marx

and

Feliciano Priego-Capote

submission deadline 28 Feb 2026 | 5 articles | Viewed by 11265 | Submission Open

Keywords: antioxidant activity; oxidative stress; reactive oxygen species; polyphenols; bioactive compounds; functional ingredients; health-promoting formulations; agrifood waste; green extraction technologies; emerging analytical methods

Oxidative and Nitrosative Stress in Male Reproduction

edited by

Pamela Uribe

and

Raúl Sánchez

submission deadline 28 Feb 2026 | 6 articles | Viewed by 10631 | Submission Open

Keywords: oxidative stress; nitrosative stress; reactive oxygen species; reactive nitrogen species; spermatozoa; sperm motility; sperm function; antioxidants

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Inflammation in Cancer Biology

edited by

Jorge Sastre-Serra

and

Mercedes Nadal-Serrano

submission deadline 28 Feb 2026 | 3 articles | Viewed by 10580 | Submission Open

Keywords: oxidative stress; antioxidant defenses; inflammation; signaling pathways; therapeutic strategies; cancer

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Antioxidant Defense in Crop Plants, 2nd Edition

edited by

Grzegorz Chrzanowski

and

Marta Jańczak-Pieniążek

submission deadline 28 Feb 2026 | 8 articles | Viewed by 10144 | Submission Open

Keywords: biotic and abiotic stress; oxidative stress; ROS; plant biostimulants; crop plants; antioxidant mechanisms; oxidative stress; antioxidant response; antioxidant enzymes

(This special issue belongs to the Section ROS, RNS and RSS)

Antioxidants and Aquaculture: A Synergistic Approach for Sustainable Aquatic Production

edited by

Yukun Zhang

Amina Moss

and Saichiro Yokoyama

submission deadline 28 Feb 2026 | 5 articles | Viewed by 10119 | Submission Open

Keywords: oxidative stress; aquatic animals; dietary antioxidants; reactive oxygen species (ROS); natural antioxidants; fish nutrition; antioxidant supplementation; environmental stressors; sustainable aquaculture; stress management

Recent Advances in Applications of Antioxidants in Livestock Health and Reproduction

edited by Weijun Pang

submission deadline 28 Feb 2026 | 5 articles | Viewed by 9736 | Submission Open

Keywords: antioxidants; livestock health; reproduction; production efficiency; disease-resistant ability; growth and development; latest progress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

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