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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Natural Antioxidants and Metabolic Diseases

edited by

José Ángel Rufián-Henares

Fortuna Iannuzzo

Maria Maisto

and

Elisabetta Schiano

submission deadline 20 Aug 2025 | 10 articles | Viewed by 24185 | Submission Open

Keywords: metabolic syndrome; antioxidant compounds; diabetes; obesity; cardiovascular diseases; biological effects; food sources; medicinal plants; oxidative stress; inflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Janus Face of Oxidative Stress in Normal and Pathological Conditions

edited by

Marco Fiore

submission deadline 20 Aug 2025 | 7 articles | Viewed by 11953 | Submission Open

Keywords: ethanol; toxicity; abuse; addiction; binge drinking; oxidative stress; psychoactive drug; cancer; recreational drug; FASD

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Reactive Nitrogen Species (RNS) and Redox Signaling in Tumors

edited by Maria Clara Franco and

Luciana Hannibal

submission deadline 20 Aug 2025 | 1 articles | Viewed by 5353 | Submission Open

Keywords: tumor biology; reactive nitrogen species; redox signaling; oxidative stress; ROS

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants Benefits in Aquaculture—3rd Edition

edited by

Ángel Isidro Cámpa-Córdova

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1102 | Submission Open

Keywords: aquaculture; invertebrates; vertebrates; oxidative stress; antioxidant response; antioxidant enzymes; antioxidant gene expression; antioxidant products

Antioxidant and Protective Effects of Plant Extracts—2nd Edition

edited by

Natale Badalamenti

Adriana Basile

and

Alessia Postiglione

submission deadline 25 Aug 2025 | 9 articles | Viewed by 9989 | Submission Open

Keywords: essential oils; plant and food extracts; antioxidant; anti-inflammatory; antimicrobial; protective effects; antiproliferative

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Innovative Analytical Pathways: Exploring Phytochemical Profiles and Bioactivities Through Advanced Instrumentation

edited by

Igor Piotr Turkiewicz

and

Karolina Tkacz

submission deadline 25 Aug 2025 | 1 articles | Viewed by 667 | Submission Open

Keywords: phytochemical profiling; bioactivity analysis; pharmacodynamics and pharmacokinetics of antioxidants; advanced instrumentation; natural antioxidants; extraction and isolation techniques; structural characterization; industrial applications of antioxidants; LC-MS; GC-MS; HRMS; NMR; FTIR

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Oxidative Stress and Lysosomal Function in Health and Disease

edited by

Silvana M. Zanlungo

and Alejandra R. Álvarez

submission deadline 29 Aug 2025 | 3 articles | Viewed by 6810 | Submission Open

Keywords: lysosome; lysosomal dysfunction; lysosome homeostasis; autophagy; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Small Molecule Approaches to Modulating Oxidative Stress Responses

edited by

Hidekazu Hiroaki

submission deadline 29 Aug 2025 | Viewed by 642 | Submission Open

Keywords: natural products; nutraceuticals; antioxidants; polyphenols; flavonoids; barrier function; cellular senescence; inflammation; DNA damage; regeneration

Oxidative Stress in Psychiatric Disorders

edited by

Wirginia Krzyściak

and Maciej Pilecki

submission deadline 29 Aug 2025 | Viewed by 374 | Submission Open

Keywords: antioxidants; oxidative stress; psychiatric disorders; mental health

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Adipose Tissue

edited by

Fátima Nogales Bueno

and

María Luisa Ojeda Murillo

submission deadline 30 Aug 2025 | 5 articles | Viewed by 29213 | Submission Open

Keywords: oxidative stress; adipose tissue; ROS; antioxidant defense

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Antioxidants in Carcinogenesis: A Multifaceted Approach

edited by

Fábio Rodrigues Ferreira Seiva

submission deadline 31 Aug 2025 | 5 articles | Viewed by 12777 | Submission Open

Keywords: cancer; tumor biology; bioactive molecules; natural compounds; free radicals; alternative treatments

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The OxInflammation Process and Tissue Repair

edited by Reggiani Vilela Gonçalves, Mariaurea Matias Sarandy and Rômulo Dias Novaes

submission deadline 31 Aug 2025 | 5 articles | Viewed by 11954 | Submission Open

Keywords: oxidative stress; inflammasome; cytokines; angiogenesis; molecular biology; cellular and molecular mechanisms; diabetes; tissue repair

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Properties and Applications of Food By-Products

edited by

Kai Wang

submission deadline 31 Aug 2025 | 7 articles | Viewed by 10373 | Submission Open

Keywords: food by-products; nutrients; extracts; bioactive compounds; antioxidant activity; physiochemical properties; functional food; value-added application

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Antioxidant Capacity of Natural Products—2nd Edition

edited by

Younghwa Kim

submission deadline 31 Aug 2025 | 8 articles | Viewed by 9354 | Submission Open

Keywords: natural product; natural antioxidant; phytochemical; chronic disease; prevention

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Oxidative Stress in Metabolic Syndrome and Cardiovascular Diseases

edited by

Anna Wai San Cheang

and Cheng-Chao Ruan

submission deadline 31 Aug 2025 | 4 articles | Viewed by 8772 | Submission Open

Keywords: oxidative stress; metabolic disorders; cardiovascular diseases; antioxidant therapeutic strategies; natural and chemical antioxidants

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Exploring Biomarkers of Oxidative Stress in Health and Disease

edited by Daniela Gradinaru and

Denisa Marilena Margină

submission deadline 31 Aug 2025 | 7 articles | Viewed by 8316 | Submission Open

Keywords: oxidative and nitrosative stress; AGEs— advanced glycation end-products; lipid peroxidation; nitrotyrosine; glutathione; 8-oxo-2'-deoxyguanosine; inflammation; cardiometabolic risk; cancer; neurodegeneration; nanoparticles; xenobiotic; antioxidant; ageing; advanced therapies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Implication of Oxidative Stress on Human Aging and Associated Pathologies

edited by

Giovanni Ricevuti

and

Salvatore Chirumbolo

submission deadline 31 Aug 2025 | 1 articles | Viewed by 8302 | Submission Open

Keywords: ROS; dementia and Alzheimer; aging; cellular senescence; senescent cells; senolitic therapy; glial cells; inflammaging; immunosenescence; inflammation; metaflammation; inflammasoma; NRF2 and NFKB; DNA methylation; glycomics; metabolomics; lipidomics; anti-senescence therapy; source of chronic inflammation in aging; oxygen ozone therapy; phytochemicals; xenobiotics; ozone; antioxidant molecules; nutrition; anti-inflammatory drugs; cardiovascular disease; medicinal plants

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants and Aquaculture: A Synergistic Approach for Sustainable Aquatic Production

edited by

Yukun Zhang

Amina Moss

and Saichiro Yokoyama

submission deadline 31 Aug 2025 | 3 articles | Viewed by 4515 | Submission Open

Keywords: oxidative stress; aquatic animals; dietary antioxidants; reactive oxygen species (ROS); natural antioxidants; fish nutrition; antioxidant supplementation; environmental stressors; sustainable aquaculture; stress management

Oxidative Stress and Antioxidant Response in Insects

edited by

José Eduardo Serrão

submission deadline 31 Aug 2025 | 3 articles | Viewed by 3832 | Submission Open

Keywords: antioxidant enzymes; invertebrates; oxidative stress; pest control; pollinators; ROS; wild animals

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant and Anti-Inflammatory Components of the Diet

edited by

Rosita Gabbianelli

submission deadline 31 Aug 2025 | 2 articles | Viewed by 3019 | Submission Open

Keywords: plant-based foods; food antioxidants; food anti-inflammatory compounds; nutrigenomics

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Lipid Peroxidation in Physiology and Chronic Inflammatory Diseases

edited by

Mario Di Gioacchino

submission deadline 31 Aug 2025 | 1 articles | Viewed by 2610 | Submission Open

Keywords: lipid peroxidation; oxidative stress; chronic inflammation; antioxidants; reactive lipid species; inflammatory signaling; redox biology; lipid mediators; disease pathogenesis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Cardiovascular Diseases and Vascular Pathophysiology

edited by

Guillermo Zalba

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1832 | Submission Open

Keywords: atherosclerosis; diabetes; heart failure; inflammation; myocardial infarction; NADPH oxidase; oxidative stress; reactive oxygen species; stroke

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

In Honor of Jiankang Liu for His Contributions and Impact on Redox and Mitochondrial Biology and Medicine

edited by

Jiangang Long

and

Zhihui Feng

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1541 | Submission Open

Keywords: redox; mitochondrial; free radical biology; aging; oxidative stress

Redox-Related Molecules in Biofilm Lifestyles

edited by

Fabio Forlani

Francesca Annunziata

and

Salvatore Princiotto

submission deadline 31 Aug 2025 | Viewed by 523 | Submission Open

Keywords: redox-related proteins; redox homeostasis; biofilm; antibiofilm compounds; biofilm modulators; bioactives; mechanistic studies

(This special issue belongs to the Section Aberrant Oxidation of Biomolecules)

Toward a Clinically Actionable Marker of Systemic Oxidative Stress

edited by Chester Lee Drum and Leroy Sivappiragasam Pakkiri

submission deadline 31 Aug 2025 | Viewed by 450 | Submission Open

Keywords: liquid chromatography– triple quadrupole mass spectrometry (LC/MS); biomarker discovery; chronic diseases; multiple reaction monitoring (MRM); oxidative stress; reactive oxygen species (ROS)

Oxidative Stress in Neurological Aging

edited by

Gunhyuk Park

Hye-Sun Lim

and Yongung Kim

submission deadline 31 Aug 2025 | Viewed by 258 | Submission Open

Keywords: antioxidants; neuron; medicinal herbs; therapeutic effects; aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Bioactive Compounds and Antioxidants in Fruits and Vegetables—2nd Edition

edited by Filomena Corbo and

Marilena Muraglia

submission deadline 31 Aug 2025 | Viewed by 188 | Submission Open

Keywords: metabolic syndrome (MetS); multi-target; polypharmacology; prevention; polyphenols; antioxidants; anti-inflammation; ageing; cancer; cardiovascular diseases; diabetes; obesity; mediterranean diet; health claim; human studies; green extraction; metabolomic; experimental design; nutrition; neuropathic pain; obesity; paediatrics

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Antioxidant Potential of Essential Oils

edited by

Riccardo Amorati

and

Christian Bergamini

submission deadline 31 Aug 2025 | Viewed by 183 | Submission Open

Keywords: essential oils; terpenes; phenols; oxidative stress; hydrodistillation; supercritical CO2; free radicals; lipid peroxidation

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Oxidative Stress Across Kingdoms in the Gut: Host Immunity, Microbiota, Oxidized Foods, and Neurotransmitter Interactions

edited by Alex Rodriguez-Palacios

submission deadline 31 Aug 2025 | Viewed by 135 | Submission Open

Keywords: oxidative stress; gut; microbiota; ROS; metabolic

Blood Cells and Redox Homeostasis in Health and Disease, 2nd Edition

edited by

Angelo D'Alessandro

and

Alkmini T. Anastasiadi

submission deadline 10 Sep 2025 | 4 articles | Viewed by 4738 | Submission Open

Keywords: blood; redox status; antioxidants; oxidative stress; redox therapy; oxidative stress biomarkers

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Advances in Oxidoreductases

edited by

Byung Cheon Lee

submission deadline 10 Sep 2025 | 1 articles | Viewed by 905 | Submission Open

Keywords: oxidoreductase; redox enzyme; metabolic regulation; signaling; cancer; immune regulation

(This special issue belongs to the Section Antioxidant Enzyme Systems)

Antioxidant Systems, Transcription Factors and Non-Coding RNAs

edited by

Raffaella Faraonio

submission deadline 15 Sep 2025 | 1 articles | Viewed by 1150 | Submission Open

Keywords: antioxidant systems; oxidative stress; transcription factors; non-coding RNAs; stress response

(This special issue belongs to the Section ROS, RNS and RSS)

Food Antioxidants and Metabolic Health: Impact on Lipid and Carbohydrate Metabolism

edited by

Miguel Rebollo-Hernanz

Ivan Luzardo-Ocampo

Alicia Gil-Ramírez

and

Diego A. Luna-Vital

submission deadline 15 Sep 2025 | Viewed by 1056 | Submission Open

Keywords: food antioxidants; lipid metabolism; carbohydrate metabolism; redox metabolism; bioenergetics; metabolic health; obesity; metabolic syndrome; diabetes; gut microbiota

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

NRF2 in Non-Communicable Diseases

edited by

Isabel Lastres-Becker

submission deadline 15 Sep 2025 | Viewed by 298 | Submission Open

Keywords: NRF2; oxidative stress; inflammation; proteostasis; mitochondria; redox homeostasis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Synthetic Compounds: Antioxidant and Anti-Inflammatory Activities, Biomedical Properties and Formulations

edited by

Simone Carradori

and

Ilaria D'Agostino

submission deadline 20 Sep 2025 | 3 articles | Viewed by 4621 | Submission Open

Keywords: antioxidants; inflammation pathways; therapeutic activity; redox potential; synthesis; preclinical studies; macrophages; immunomodulation; packaging; formulations; topical application; polymers; nanotechnology; cytotoxicity; mechanism of action; food; drug design

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Mitochondrial Oxidative Stress and Inflammation

edited by Aldrin V. Gomes

submission deadline 20 Sep 2025 | 2 articles | Viewed by 4347 | Submission Open

Keywords: oxidative stress; mitochondria; antioxidants; disease; inflammation; mitochondrial oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Cigarette Smoke and Oxidative Stress

edited by

Lorenzo Loffredo

submission deadline 20 Sep 2025 | 1 articles | Viewed by 861 | Submission Open

Keywords: smoking; cardiovascular diseases; oxidative stress; cigarettes

Innovative Approaches to Antioxidant Activity and Polyphenol Extraction

edited by José Ricardo Pérez-Correa and

María Salomé Mariotti-Celis

submission deadline 20 Sep 2025 | Viewed by 383 | Submission Open

Keywords: polyphenols; novel antioxidant activity methods; sustainable separation technologies; innovative application techniques

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Exploring New Frontiers in Oxidative Stress and Antioxidant Research: From Model Organisms to Human Disease

edited by

Marcello Ziosi

and

Gaetano Santulli

submission deadline 22 Sep 2025 | 1 articles | Viewed by 340 | Submission Open

Keywords: oxidative stress; antioxidant therapeutics; cell death and survival pathways; cellular signaling networks; gene regulation and expression

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Adaptive Responses to Oxidative Stress: Insights from Molecular, Cellular, and Animal Studies

edited by Ghasem Rashidian and

Caterina Faggio

submission deadline 24 Sep 2025 | 2 articles | Viewed by 1904 | Submission Open

Keywords: oxidative stress; antioxidant capacity; adaptive oxidative response; xenobiotics; pollutants; pesticides; natural antioxidants; antioxidant enzymes; reactive oxygen species (ROS); lipid peroxidation; redox homeostasis; oxidative damage; aquatic toxicology; stress response pathways; environmental stressors; cellular defense mechanisms; adaptive responses

Dietary Antioxidant Compounds and Liver Health: Pharmacological Activities and Molecular Mechanisms

edited by Juan Socorro Armendariz-Borunda, Marina Galicia-Moreno and Hugo Christian Monroy-Ramirez

submission deadline 25 Sep 2025 | 1 articles | Viewed by 843 | Submission Open

Keywords: liver; oxidative stress; antioxidants; natural foods; MAFLD; NAFLD; obesity; liver function; hepatitis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants and Antioxidant Mechanisms in the Prevention and Treatment of Infectious Diseases

edited by

Gabriele Carullo

Maria Dichiara

Valeria Tudino

and Sara Rossi

submission deadline 25 Sep 2025 | Viewed by 181 | Submission Open

Keywords: antioxidants; infectious diseases; quorum sensing; inflammation; natural and synthetic antioxidants; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Signaling in Brain Aging and Neurodegeneration

edited by Marco Bisaglia

submission deadline 28 Sep 2025 | 2 articles | Viewed by 1714 | Submission Open

Keywords: aging; autophagy; brain; Alzheimer disease; amyotrophic lateral sclerosis; Friedreich ataxia; Huntington disease; neurodegeneration; oxidative stress; protein aggregation; Parkinson’ s disease; reactive oxygen species

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Bioactive Compounds: Antioxidant, Antibacterial, Anti-inflammatory Modulation

edited by

Raquel Bridi

and

Christian Espinosa-Bustos

submission deadline 30 Sep 2025 | 18 articles | Viewed by 84817 | Submission Open

Keywords: bioactive compounds; antioxidants; inflammation; antibacterial; reactive oxygen species

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Prevention of Atherosclerosis and of Low-Density Lipoprotein Oxidation: Role of Dietary Antioxidant Compounds and Altered Redox Pathways. A Commemorative Special Issue in Honour of Professor Stanley Omaye

edited by

Alessandra Napolitano

and

Mario Allegra

submission deadline 30 Sep 2025 | 5 articles | Viewed by 20559 | Submission Open

Keywords: LDL; oxidative stress; antioxidants; chronic; low-grade inflammation; vitamins; antioxidant enzymes; redox signalling

Role of Natural Antioxidants on Neuroprotection

edited by

Mercedes Villacampa

José Carlos Menéndez

and

Ángel Cores

submission deadline 30 Sep 2025 | 6 articles | Viewed by 15454 | Submission Open

Keywords: drug design; polyphenols; oxidative stress; Nrf2 induction; neuroinflammation; neurodegenerative diseases

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants from Sustainable Food Sources

edited by

Kevin Kantono

and

Nazimah Hamid

submission deadline 30 Sep 2025 | 10 articles | Viewed by 13981 | Submission Open

Keywords: natural products; food processing; green technology

Use of Antioxidant Supplementation in Aquaculture: Impact on Growth, Health, and Product Quality

edited by

Luisa M. P. Valente

and Marta Monteiro

submission deadline 30 Sep 2025 | 5 articles | Viewed by 9158 | Submission Open

Keywords: functional feeds; oxidative stress; antioxidant supplementation; flesh quality; stress resilience

Antioxidant Capacity of Anthocyanins and Other Vegetal Pigments: Properties, Intake and Health Benefits

edited by

Agustín G. Asuero

Noelia Tena

and

Julia Martín

submission deadline 30 Sep 2025 | 7 articles | Viewed by 7997 | Submission Open

Keywords: anthocyanins; polyphenols; betalains; chlorophylls; carotenoids; antioxidant capacity; oxidative stress; bioavailability; intake

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Oxidative Stress in Chronic Diseases: A Focus on Rheumatoid Arthritis

edited by

Isaias Dichi

, Alexandre Meira Pazelli and

Bruna Miglioranza Scavuzzi

submission deadline 30 Sep 2025 | 2 articles | Viewed by 7752 | Submission Open

Keywords: rheumatic disorders; autoimmune conditions; oxidative stress; inflammation; redox state; antioxidant therapy

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