Special Issues

Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Antioxidant Peptides submission deadline 10 May 2026 | 6 articles | Viewed by 12912 | Submission Open
Keywords: structure– activity relationships; novel natural or synthetic sources; advanced delivery systems; roles in preventing or alleviating oxidative stress-related diseases.
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Bioactive Antioxidants from Agri-Food Wastes, 2nd Edition submission deadline 10 May 2026 | 2 articles | Viewed by 1792 | Submission Open
Keywords: agri-food byproducts; waste; food industry; additives; packaging
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Natural Compounds in Neurogenesis, Neurodevelopment, and the Attenuation of Neurotoxicity: Insights from Animal Models submission deadline 10 May 2026 | Viewed by 293 | Submission Open
Keywords: neurogenesis; neurodevelopment; neurotoxicity; antioxidant activity; brain development
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Health Implications of Vitamin E and Its Analogues and Metabolites
edited by Jean-Marc Zingg, and
submission deadline 15 May 2026 | 1 articles | Viewed by 3504 | Submission Open
Keywords: vitamin E; antioxidant; non-antioxidant; bioavailability; bioactivity; signalling; gene expression
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Cigarette Smoke and Oxidative Stress
edited by
submission deadline 20 May 2026 | 6 articles | Viewed by 13361 | Submission Open
Keywords: smoking; cardiovascular diseases; oxidative stress; cigarettes
Redox Regulation in COPD: Therapeutic Implications of Antioxidants submission deadline 20 May 2026 | 2 articles | Viewed by 3831 | Submission Open
Keywords: COPD; oxidative stress; antioxidants; pulmonary diseases; therapeutics
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Phenolics as Antioxidant Agents—2nd Edition
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 369 | Submission Open
Keywords: antioxidants; bioactive compounds; oxidative stress; structure– activity relationships (SARs); sustainable extraction; green chemistry; therapeutic potential; in vitro and in vivo models; food and biomedical applications
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Antioxidants in Health and Disease: Environmental Challenges, Redox Homeostasis, and Adaptive Responses
edited by
submission deadline 20 May 2026 | Viewed by 303 | Submission Open
Keywords: antioxidants; redox biology; oxidative stress; environmental exposures; adaptive responses; resilience; Nrf2 pathway; endogenous antioxidants; exogenous antioxidants; cellular homeostasis; environmental toxicology; climate-related stress; human health; chronic disease; prevention; therapeutic strategies
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Plant and Algal Antioxidants in Stress Defence
edited by Petra Peharec Štefanić and
submission deadline 20 May 2026 | Viewed by 234 | Submission Open
Keywords: plant antioxidants; algal antioxidants; oxidative stress; bioactive compounds; ROS; abiotic stress; biotic stress; antioxidant enzymes; secondary metabolites; stress physiology; phytochemicals; natural antioxidants
(This special issue belongs to the Section ROS, RNS and RSS)
Antioxidant Research in Chile—2nd Edition submission deadline 30 May 2026 | 9 articles | Viewed by 18192 | Submission Open
Keywords: antioxidants; biotechnology; biomedicine; natural products; nutrition; oxidative stress; Chilean plants of economic importance; polyphenols; flavonoids; anthocyanins; phenolic acids; resveratrol; food waste; plant extracts; neuroinflammation; redox signaling; circular economy; ROS scavengers; antioxidants in industry; entrepreneurship; green startups
Oxidative Stress in Livestock and Poultry—3rd Edition
edited by and
submission deadline 30 May 2026 | 6 articles | Viewed by 13269 | Submission Open
Keywords: oxidative stress; environmental stressors; gut microbiome; antioxidant strategies; epigenetic modifications
Oxidative Stress in Plant Stress and Plant Physiology
edited by
submission deadline 30 May 2026 | 4 articles | Viewed by 4904 | Submission Open
Keywords: ROS signaling; stress adaptive responses; halophyte vs glycophyte; redox homeostasis; molecular crosstalk with  ROS signaling; biotic; abiotic; soil borne; and air pollutants
(This special issue belongs to the Section ROS, RNS and RSS)
Innovative Analytical Pathways: Exploring Phytochemical Profiles and Bioactivities Through Advanced Instrumentation submission deadline 30 May 2026 | 1 articles | Viewed by 1869 | Submission Open
Keywords: phytochemical profiling; bioactivity analysis; pharmacodynamics and pharmacokinetics of antioxidants; advanced instrumentation; natural antioxidants; extraction and isolation techniques; structural characterization; industrial applications of antioxidants; LC-MS; GC-MS; HRMS; NMR; FTIR
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Glutathione Redox Cycle, 2nd Edition
edited by
submission deadline 30 May 2026 | Viewed by 336 | Submission Open
Keywords: glutathione; oxidized glutathione; glutathione metabolism; glutathione biosynthesis; glutathione homeostasis; thiol redox status; disulfide; GSH; GSSG
(This special issue belongs to the Section Antioxidant Enzyme Systems)
The OxInflammation Process and Tissue Repair
edited by Reggiani Vilela Gonçalves, Mariaurea Matias Sarandy and Rômulo Dias Novaes
submission deadline 31 May 2026 | 6 articles | Viewed by 26549 | Submission Open
Keywords: oxidative stress; inflammasome; cytokines; angiogenesis; molecular biology; cellular and molecular mechanisms; diabetes; tissue repair
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Multi-Target Profile of Antioxidant Compounds, Including Repurposing and Combination Strategies—2nd Edition
edited by
submission deadline 31 May 2026 | 5 articles | Viewed by 15595 | Submission Open
Keywords: polypharmacology; multi-target ligands; rational drug; design repurposing; off-target effects; computational techniques
Lipid Peroxidation in Physiology and Chronic Inflammatory Diseases submission deadline 31 May 2026 | 2 articles | Viewed by 11445 | Submission Open
Keywords: lipid peroxidation; oxidative stress; chronic inflammation; antioxidants; reactive lipid species; inflammatory signaling; redox biology; lipid mediators; disease pathogenesis
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress in Hepatic Diseases
edited by
submission deadline 31 May 2026 | 4 articles | Viewed by 10849 | Submission Open
Keywords: oxidative stress; hepatic diseases; liver fibrosis; reactive oxygen species (ROS); mitochondrial dysfunction; lipid peroxidation; antioxidant defense; non-alcoholic fatty liver disease (NAFLD); alcoholic liver disease; hepatoprotective strategies
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress in Animal Reproduction and Nutrition
edited by and
submission deadline 31 May 2026 | 8 articles | Viewed by 10823 | Submission Open
Keywords: oxidative stress; antioxidants; animal reproduction; nutritional regulation; livestock and poultry; mouse or rat model; antioxidant mechanisms; oxidative stress mechanisms
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Plants and Plant-Based By-Products as Valuable Sources of Antioxidants: Current Tendencies and Achievements in Their Exploitation
edited by Svetlana Momchilova and
submission deadline 31 May 2026 | 7 articles | Viewed by 10159 | Submission Open
Keywords: antioxidants; oxidative stability; antioxidant activity; lipid oxidation; green chemistry; biomass; plants and by-products; herbs; utilization
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Innovative Technologies for Detecting Antioxidant Properties and Oxidative Stabilization of Agri-Food Products and Plant Extracts
edited by
submission deadline 31 May 2026 | 3 articles | Viewed by 10122 | Submission Open
Keywords: green extraction; plant extracts; bioactive compounds; flavonoids; polyphenols; detection technologies; antioxidant activity
(This special issue belongs to the Section Methods for Antioxidants Evaluation/Measurement)
Roles of NADPH Oxidase in Modulation of Signal Transduction and Cellular Metabolism—2nd Edition submission deadline 31 May 2026 | 4 articles | Viewed by 9933 | Submission Open
Keywords: redox signaling; inflammation; NADPH oxidase; ROS; cell metabolism; redox-state; Warburg effect; metabolic reprogramming; tumor microenvironment; cell proliferation
(This special issue belongs to the Section Antioxidant Enzyme Systems)
Cellular ROS and Antioxidants: Physiological and Pathological Role—2nd Edition submission deadline 31 May 2026 | 5 articles | Viewed by 9120 | Submission Open
Keywords: reactive oxygen and nitrogen species; intracellular signaling; oxidative stress; iron metabolism; mitochondrial dysfunction; hypoxia; inflammation; targeted and untargeted antioxidants; gas messengers natural and artificial sources of reactive oxygen species; antioxidant defense systems; small signaling molecules; oxidative stress-driven processes
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Bioactive Compounds from Natural Sources with Antioxidant and Anti-Inflammatory Potential
edited by
submission deadline 31 May 2026 | 8 articles | Viewed by 8122 | Submission Open
Keywords: antioxidant; anti-inflammatory; natural compounds; isolation; extraction; molecular mechanism; synergistic effect; clinical trial; bioavailability; analytical method; pharmacodynamics; pharmacokinetics
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Oxidative Stress in Age-Related Diseases submission deadline 31 May 2026 | 3 articles | Viewed by 6899 | Submission Open
Keywords: aging; age-related diseases; frailty; oxidative stress; reductive stress; redox homeostasis; antioxidants
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress Mechanisms and Parkinson's Disease Treatment submission deadline 31 May 2026 | 2 articles | Viewed by 5015 | Submission Open
Keywords: Parkinson’ s disease; dopamine; dopamine oxidation; neuromelanin; dopaminergic neurons; antioxidants; neuroprotection; neurodegeneration; oxidative stress; protein degradation dysfunction; neuroinflammation; mitochondrial dysfunction; endoplasmic reticulum stress; alpha-synuclein oligomers; glutathione; glutathione transferase; DT-diaphorase; preclinical model for Parkinson's disease; VMAT2; dopamine transporter; tyrosine hydroxylase; dopamine-derived orto-quinones
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and NRF2 in Diabetes
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 4057 | Submission Open
Keywords: oxidative stress; NRF2; ROS; diabetes; diabetes-related complications; insulin
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress During Physical Activity
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 3584 | Submission Open
Keywords: physical activity; exercise; oxidative stress; reactive oxygen species (ROS); redox balance; cellular damage; skeletal muscle
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Role of Oxidative Stress in Cardiac Remodeling and Heart Failure—3rd Edition submission deadline 31 May 2026 | 2 articles | Viewed by 3049 | Submission Open
Keywords: oxidative stress; heart disease; cardiac remodeling; signaling pathways; remodeling; left ventricular dysfunction; heart failure; cardiovascular disease; myocardial damage
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Hydrogen Sulfide, Reactive Sulfur Species, and Donor Compounds: Natural and Synthetic Tools for Physiology and Disease submission deadline 31 May 2026 | 1 articles | Viewed by 2751 | Submission Open
Keywords: hydrogen sulfide; H2S donors; H2S hybrid compounds; H2S sources; pharmacological tools; H2S signaling
Oxidative Stress as a Therapeutic Target of Alzheimer’s Disease—2nd Edition submission deadline 31 May 2026 | 2 articles | Viewed by 2460 | Submission Open
Keywords: Alzheimer's disease; oxidative stress; therapeutic target; antioxidant; neurodegeneration
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Inhibition of Oxidative Stress and Related Signaling Pathways in Neuroprotection—3rd Edition submission deadline 31 May 2026 | 1 articles | Viewed by 1642 | Submission Open
Keywords: neuroprotection; neurotoxicity; antioxidative vs. prooxidative activity; antioxidant capacity; signaling pathways; redox metals; apoptosis; ferroptosis; cuproptosis; autophagy
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Mitochondrial Dysfunction and Oxidative Stress in Aging and Age-Related Disorders
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 1386 | Submission Open
Keywords: mitochondrial dysfunction; oxidative stress; aging; age-related diseases; mitochondrial biogenesis; reactive oxygen species (ROS); mitochondrial quality control; redox homeostasis; cellular senescence; neurodegeneration
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Redox Regulation of Cancer Metabolism
edited by , Adriana Celesia and Alessia Cardile
submission deadline 31 May 2026 | 1 articles | Viewed by 1372 | Submission Open
Keywords: redox homeostasis; cancer metabolism; reactive oxygen species (ROS); metabolic reprogramming; oxidative stress; Nrf2; HIF-1α ; mitochondrial metabolism; antioxidant therapy; metabolic vulnerabilities
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Vitamins, Antioxidants, and Neurodegeneration: Exploring Protective Strategies in Brain Health
edited by
submission deadline 31 May 2026 | 2 articles | Viewed by 1300 | Submission Open
Keywords: neurodegenerative diseases; alzheimer's disease; parkinson's disease; amyotrophic lateral sclerosis (ALS); aging populations; vitamins; antioxidants; oxidative stress; neuroinflammation
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and Precision Medicine in Cardiometabolic and Cardiovascular Disease: Mechanisms, Biomarkers, and Therapeutic Targets
edited by Leroy Sivappiragasam Pakkiri and Chester Lee Drum
submission deadline 31 May 2026 | 1 articles | Viewed by 1262 | Submission Open
Keywords: oxidative stress; precision medicine; cardiometabolic disease; cardiovascular disease; redox signaling
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress in Cancers of the Female Reproductive Tract: Bridging Current Knowledge with New Technologies
edited by Ioannis A. Kalogiannidis and
submission deadline 31 May 2026 | 1 articles | Viewed by 1251 | Submission Open
Keywords: oxidative stress; female reproductive cancers; reactive oxygen species (ROS); antioxidant mechanisms; therapeutic target
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
The Effects of Antioxidants as Supplements on Exercise Performance and Recovery
edited by and Rossella Rotondo
submission deadline 31 May 2026 | 1 articles | Viewed by 1182 | Submission Open
Keywords: exercise performance; exercise recovery; oxidative stress; antioxidants; sport nutrition; sport supplements; detoxification systems
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant and Antimicrobial Activity of Honey Bee Products—3rd Edition submission deadline 31 May 2026 | 1 articles | Viewed by 1111 | Submission Open
Keywords: honey bee products; antioxidant capacity; antimicrobial efficacy; polyphenol content; functional food; health promotion
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Melanoma and Redox Dynamics: A Crucial Tug-of-War in Tumor Onset and in Therapy Response submission deadline 31 May 2026 | 1 articles | Viewed by 918 | Submission Open
Keywords: melanoma; redox homeostasis; ROS; antioxidants; therapy resistance; cancer metabolism; mitochondria; epigenetic changes; innovative therapeutic and experimental approaches
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Activities of Nanomaterials: Mechanisms, Applications, and Technological Potential submission deadline 31 May 2026 | 1 articles | Viewed by 591 | Submission Open
Keywords: antioxidant nanomaterials; nano-antioxidants; oxidative Stress; free radical scavenging; nanomedicine
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Oxidative Stress in Cancers submission deadline 31 May 2026 | 1 articles | Viewed by 524 | Submission Open
Keywords: cancer; oxidative stress; ROS; antioxidants; combined therapy; cellular death
Oxidative Stress and Neuroinflammation in Alzheimer’s Disease: Molecular Mechanisms and Therapeutic
edited by
submission deadline 31 May 2026 | Viewed by 280 | Submission Open
Keywords: Alzheimer’ s Disease; oxidative stress; neuroinflammation; antioxidants; amyloid beta; tau pathology; mitochondrial dysfunction; micoglia activation; cell death regulation; therapeutic natural products
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Anti-Cancer Potential of Plant-Based Antioxidants—2nd Edition submission deadline 31 May 2026 | Viewed by 250 | Submission Open
Keywords: antioxidants; cancer; carotenoids; medicinal plants; nutraceuticals; oxidative stress; polyphenols; terpenoids
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Properties and Applications of Food By-Products—2nd Edition
edited by
submission deadline 31 May 2026 | Viewed by 221 | Submission Open
Keywords: food by-products  ; nutrients  ; extracts  ; bioactive compounds  ; antioxidant activity  ; physiochemical properties  ; functional food; value-added application
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Advances in Analysis of Antioxidant-Rich Medicinal Plants, Functional Foods and Food Supplements submission deadline 31 May 2026 | Viewed by 195 | Submission Open
Keywords: antioxidants; bioactive compounds; extraction; medicinal plants; natural products; instrumental analysis; chromatography; spectrometry; biological activity; chemometrics; structure– activity relationship
(This special issue belongs to the Section Methods for Antioxidants Evaluation/Measurement)
Advances in Oxidative Stability of Foods
edited by
submission deadline 31 May 2026 | Viewed by 184 | Submission Open
Keywords: food chemistry; oxidative stability; food processing; food storage; food engineering; antioxidants; food science
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Antioxidant Role of High-Density Lipoprotein—2nd Edition
edited by Paul Durrington
submission deadline 31 May 2026 | Viewed by 182 | Submission Open
Keywords: lipoprotein oxidation; cell membrane oxidation; HDL antioxidant activity; glycosylation; atherosclerosis; paraoxonase
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Peptides from Marine Organisms: Structural Insights, Functional Mechanisms, and Sustainable Applications
edited by Changfeng Chi
submission deadline 1 Jun 2026 | 1 articles | Viewed by 2727 | Submission Open
Keywords: marine peptides; antioxidant activity; structure identification; structural modification; bioactivity and function; structure; function relationship; functional foods; biodiversity; organismic diversity and diversity preservation; genetic diversity
Oxidative Stress in Lung Diseases
edited by
submission deadline 15 Jun 2026 | 4 articles | Viewed by 15938 | Submission Open
Keywords: ROS; RNS; lung diseases; antioxidant defense; respiratory health
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
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