Special Issues

Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Antioxidants in Prevention and Treatment of Diabetes
edited by Karima Zitouni and Kenneth Earle
submission deadline 30 Nov 2026 | 3 articles | Viewed by 3249 | Submission Open
Keywords: diabetic vasculopathy; oxidative stress; type 2 diabetes; antioxidant defenses
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Mitochondria, Redox and Pancreatic β-Cells: Maturation, Function and Inflammatory Stress
edited by Sarah Zangen
submission deadline 30 Nov 2026 | 2 articles | Viewed by 3067 | Submission Open
Keywords: pancreatic β-cell mitochondria; redox; ETC dysfunction; electron ROS/RNS; mitophagy; UPR^mt; antioxidant defenses; cytokines; inflammasome; iPSC/islet organoids; biomarkers; therapeutics
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidants in Food Matrices: From Analytical Advances to Circular and Sustainable Applications submission deadline 30 Nov 2026 | 1 articles | Viewed by 2225 | Submission Open
Keywords: food matrix; bioaccesibility; bioavailability; functionality; by-products; valorization; circular economy
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Next-Generation Insights into Anthocyanins and Phytopigments: Bioactivity, Bioavailability, and Health Impacts submission deadline 30 Nov 2026 | 2 articles | Viewed by 2179 | Submission Open
Keywords: anthocyanins; phytopigments; antioxidant activity; bioavailability; metabolic transformation; dietary supplements; chronic disease prevention
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Oxidative Stress in Osteoclast Metabolism: Implications for Bone Disease Treatment
edited by
submission deadline 30 Nov 2026 | 2 articles | Viewed by 2167 | Submission Open
Keywords: bone; osteoclast; oxidative stress; antioxidants; Nrf2; miRNA; osteoporosis; arthritis; periodontal disease
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
One Health and Oxidative Stress: Environmental Drivers, Molecular Pathways, and Disease Risk submission deadline 30 Nov 2026 | 2 articles | Viewed by 2145 | Submission Open
Keywords: one health; environmental exposures; environmental epidemiology; cardiovascular disease; cancer; mitochondrial dysfunction; epigenetics; oxidative stress; antioxidants; toxicology
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Therapeutic Potential of Natural Antioxidants in Respiratory Diseases and Airway Inflammation
edited by Yo-Han Han
submission deadline 30 Nov 2026 | 1 articles | Viewed by 1779 | Submission Open
Keywords: natural product; acute/chronic lung injury; inflammation; oxidative stress
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Melanoma and Redox Dynamics: A Crucial Tug-of-War in Tumor Onset and in Therapy Response submission deadline 30 Nov 2026 | 1 articles | Viewed by 1762 | Submission Open
Keywords: melanoma; redox homeostasis; ROS; antioxidants; therapy resistance; cancer metabolism; mitochondria; epigenetic changes; innovative therapeutic and experimental approaches
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidants from Agri-Food Byproducts: Effects on Metabolic Syndrome and Skin Health submission deadline 30 Nov 2026 | 2 articles | Viewed by 1568 | Submission Open
Keywords: agri-food byproducts; antioxidants; bioactive compounds; oxidative stress; polyphenols; anti-inflammatory activity; skin health; cosmeceuticals; nutraceuticals; sustainable valorization
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Defenses and Inflammation in Diabetic Retinopathy
edited by Devy Deliyanti
submission deadline 30 Nov 2026 | 2 articles | Viewed by 1084 | Submission Open
Keywords: retinal injury; diabetic retinopathy; retinal inflammation; cell death; antioxidant; pro-oxidants; oxidative stress
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and Cardioprotection in Ischemia/Reperfusion Injury: Mechanisms, Biomarkers, and Therapeutic Approaches
edited by Anna Krzywonos-Zawadzka, Agnieszka Jaźwa-Kusior and Iwona Bil-Lula
submission deadline 30 Nov 2026 | Viewed by 973 | Submission Open
Keywords: mitochondrial dysfunction; reactive oxygen species (ROS); cardioprotective strategies; conditioning strategies
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant Role of High-Density Lipoprotein—2nd Edition
edited by Paul Durrington
submission deadline 30 Nov 2026 | 1 articles | Viewed by 970 | Submission Open
Keywords: lipoprotein oxidation; cell membrane oxidation; HDL antioxidant activity; glycosylation; atherosclerosis; paraoxonase
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Innovative Processing for Bioactive and Antioxidant Recovery in Foods submission deadline 30 Nov 2026 | Viewed by 481 | Submission Open
Keywords: bioactive compounds; antioxidant recovery; innovative extraction techniques
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Redox Modulation in Neurodegenerative Disorders: A Focus on Epigenetic Regulation
edited by
submission deadline 30 Nov 2026 | Viewed by 332 | Submission Open
Keywords: redox signaling; oxidative stress; epigenetics; DNA methylation; histone modification; chromatin remodeling; noncoding RNA; mitochondrial dysfunction; neurodegeneration; biomarkers
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Advanced in the Protective Action of Antioxidant Signalling Mediators on Skeletal Muscle Regeneration
edited by
submission deadline 30 Nov 2026 | Viewed by 331 | Submission Open
Keywords: skeletal muscle (SkM); antioxidant signalling; reactive oxygen species (ROS); muscle stem cells (MuSCs)
Oxidative Stress Induced by Environmental Pollution
edited by Lina Mu
submission deadline 30 Nov 2026 | Viewed by 286 | Submission Open
Keywords: environmental exposure; oxidative stress; antioxidants; emerging contaminants; reactive oxygen species (ROS); toxins; chronic diseases; molecular mechanisms; health impacts; environmental health
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress in Heart Disease
edited by Aldrin V. Gomes
submission deadline 30 Nov 2026 | Viewed by 282 | Submission Open
Keywords: reactive oxygen species (ROS); redox signaling; ischemia–reperfusion injury; mitochondrial dysfunction; cardiac hypertrophy; myocardial infarction; oxidative stress; antioxidant defense; atherosclerosis
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress in Eye Diseases—2nd Edition submission deadline 30 Nov 2026 | Viewed by 279 | Submission Open
Keywords: oxidative stress; antioxidants; reactive oxygen species; redox signaling; inflammatory cell death; age-related blinding diseases; age-related macular degeneration; retinal disorder; lens
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress in Brain Function—3rd Edition
edited by
submission deadline 30 Nov 2026 | Viewed by 262 | Submission Open
Keywords: pathophysiological; brain function; oxidative stress ; brain damage ; neurodegeneration; cellular signaling; neurotoxicity; excitotoxicity; synaptic transmission; cognitive function
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
The Role of NRF2 in Cardiovascular Health and Disease
edited by Elena N. Dedkova
submission deadline 30 Nov 2026 | Viewed by 243 | Submission Open
Keywords: NRF2 as a therapeutic target; oxidative stress; redox signaling; cardiovascular disease; cardiac remodeling; heart failure; ischemia–reperfusion injury; Friedreich ataxia; mitochondrial dysfunction; inflammation; ferroptosis; autophagy; environmental stressors; translational research; therapeutic targeting; small-molecule activators; biomarkers
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Bioactive Compounds of Essential Oils: Chemical Characterization, Antioxidant Mechanisms, and Functional Properties submission deadline 30 Nov 2026 | Viewed by 228 | Submission Open
Keywords: essential oils; bioactive compounds; antioxidant activity; chemical characterization; structure–activity relationships; stability and degradation kinetics; toxicological evaluation; cytotoxicity
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Medicinal Plant Extracts for Modulation of Oxidative Stress and Associated Disorders
edited by
submission deadline 30 Nov 2026 | Viewed by 221 | Submission Open
Keywords: phytotherapy; bioactive compounds; natural antioxidants; polyphenolic compounds; oxidative stress modulation; chronic diseases
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Mitochondrial Redox Signalling and Regulated Cell Death Pathways: New Insights into Disease Mechanisms and Therapy
edited by Seung Jae Hyeon
submission deadline 30 Nov 2026 | Viewed by 213 | Submission Open
Keywords: mitochondrial ROS; redox signalling; regulated cell death; oxidative stress; therapeutic targets
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Redox Imbalance and Antioxidants in Gut–Liver Axis Dysfunction: A Focus on Dysbiosis and Microbial Metabolites
edited by and Laura Mahdi
submission deadline 30 Nov 2026 | Viewed by 170 | Submission Open
Keywords: gut–liver axis; oxidative stress; dysbiosis; microbial metabolites
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Reactive Oxygen Species in Cancer and Viral Diseases: A Double-Edged Sword
edited by Eduardo Maldonado and
submission deadline 30 Nov 2026 | Viewed by 160 | Submission Open
Keywords: reactive oxygen species (ROS); oxidative stress; mitochondria; cancer; viral infections; redox homeostasis; antioxidant defenses; chemotherapy; electron transport chain; ROS-mediated cytotoxicity
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidant and Anti-Inflammatory Properties of Mushrooms: From Structure to Functionality
edited by
submission deadline 1 Dec 2026 | 4 articles | Viewed by 18655 | Submission Open
Keywords: mushroom; antioxidants; metabolic syndrome; functional food; nutraceuticals; polysaccharides; phenolics; terpenoids
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Redox Mechanisms in Obesity-Induced Organ Injury: Potential Therapeutic Opportunities
edited by and Stefania Melini
submission deadline 10 Dec 2026 | Viewed by 182 | Submission Open
Keywords: redox signaling; oxidative stress; metabolic diseases; mitochondrial dysfunction; inflammation; liver; brain; MAFLD (metabolic dysfunction-associated fatty liver disease); MASH (metabolic dysfunction-associated steatohepatitis); cardiometabolic diseases
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Bioactive Antioxidants from Agri-Food Wastes, 2nd Edition submission deadline 20 Dec 2026 | 3 articles | Viewed by 4244 | Submission Open
Keywords: agri-food byproducts; waste; food industry; additives; packaging
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Targeting Mitochondrial Dysfunction and Oxidative Stress for Neuroprotection
edited by
submission deadline 25 Dec 2026 | Viewed by 194 | Submission Open
Keywords: oxidative stress; mitochondrial dysfunction; neurodegeneration; Alzheimer’s disease; Parkinson’s disease; biomarkers
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Iron Metabolism and Oxidative Stress in Brain Ageing and Neurodegenerative Diseases
edited by
submission deadline 26 Dec 2026 | Viewed by 372 | Submission Open
Keywords: iron metabolism; redox balance; oxidative stress; neurodegenerative diseases; brain ageing; ferroptosis; metal homeostasis; antioxidant systems; brain iron imaging
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Novel Antioxidant Mechanisms for Health and Diseases, 2nd Edition
edited by Yoshihisa Koyama
submission deadline 30 Dec 2026 | 6 articles | Viewed by 14296 | Submission Open
Keywords: antioxidant therapy; reactive oxygen species; oxidative stress; nano-antioxidant therapy; nutrigenomics; microbiome
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Unveiling the Essential Role of Coenzyme Q in Health submission deadline 30 Dec 2026 | 5 articles | Viewed by 10759 | Submission Open
Keywords: coenzyme Q10; CoQ biosynthesis; ROS; cognitive deficiency; cardiovascular disease
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Redox Resilience Signaling of Functional Nutrients and Neurotoxicant Pollutants for Human Health submission deadline 30 Dec 2026 | 2 articles | Viewed by 5843 | Submission Open
Keywords: dietary nutrients; polyphenol-basaed nanoparticles; oxidative stress; apoptosis; ferroptosis; pyroptosis; hormesis; inflammation; human health; toxicant pollutants; apoptosis; cancer; nervous system disorders; personalized nutritional therapy
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Nrf2 and Cardiovascular Function, Diseases, and Therapeutic Targets
edited by and
submission deadline 30 Dec 2026 | 3 articles | Viewed by 4260 | Submission Open
Keywords: nuclear factor erythroid 2-related factor 2 (Nrf2); Nrf2-targeted therapies; cardiovascular diseases; antioxidant; oxidative stress
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Bioactivity Mechanisms of Antioxidant Compounds from Natural Products
edited by
submission deadline 30 Dec 2026 | 3 articles | Viewed by 1197 | Submission Open
Keywords: natural antioxidants; molecular mechanisms; bioavailability; pharmacokinetics; structure–activity relationships
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Plant and Algal Antioxidants in Stress Defence
edited by Petra Peharec Štefanić and
submission deadline 30 Dec 2026 | 1 articles | Viewed by 922 | Submission Open
Keywords: plant antioxidants; algal antioxidants; oxidative stress; bioactive compounds; ROS; abiotic stress; biotic stress; antioxidant enzymes; secondary metabolites; stress physiology; phytochemicals; natural antioxidants
(This special issue belongs to the Section ROS, RNS and RSS)
Oxidative Stress in Respiratory Diseases—Second Edition submission deadline 30 Dec 2026 | Viewed by 636 | Submission Open
Keywords: reactive oxygen species; inflammation; antioxidant therapy; chronic obstructive pulmonary disease; asthma; cystic fibrosis; nitrosative stress
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Bioactive Natural Compounds and Their Derivatives in Cancer: Redox Signaling, Molecular Mechanisms and Translational Opportunities submission deadline 30 Dec 2026 | Viewed by 278 | Submission Open
Keywords: bioactive natural compounds; derivatives; cancer; redox signaling; molecular mechanisms; translational oncology
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Exploring New Frontiers in Oxidative Stress and Antioxidant Research: From Model Organisms to Human Disease submission deadline 31 Dec 2026 | 6 articles | Viewed by 18699 | Submission Open
Keywords: oxidative stress; antioxidant therapeutics; cell death and survival pathways; cellular signaling networks; gene regulation and expression
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Editorial Board Members’ Collection Series: Advances in Redox-Tools and Therapies in Cardiovascular Disease submission deadline 31 Dec 2026 | 5 articles | Viewed by 12458 | Submission Open
Keywords: cardiovascular disease; oxidative stress; inflammation; reactive oxygen species; redox signalling
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Natural Antioxidants in Functional Foods
edited by , Palmira De Bellis and
submission deadline 31 Dec 2026 | 12 articles | Viewed by 12266 | Submission Open
Keywords: polyphenols; functional foods; fermentation; antioxidant activity; anti-inflammatory activity
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and Inflammation in Kidney Diseases
edited by
submission deadline 31 Dec 2026 | 6 articles | Viewed by 11982 | Submission Open
Keywords: chronic renal failure; clinical nephrology; renal physiology; glomerulonephritis; diabetic nephropathy; renal disease; oxidative stress; kidney transplantation
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Based on Antioxidant Capacity: The Multifunctional Roles of Bioactive Compounds from Fruits and Vegetables in Precision Nutrition
edited by
submission deadline 31 Dec 2026 | 4 articles | Viewed by 9250 | Submission Open
Keywords: fruits and vegetables; antioxidants; anti-inflammatory; plant compounds; health
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Oxidative Stress and Human Reproduction
edited by Sofoklis Stavros and Despoina Mavrogianni
submission deadline 31 Dec 2026 | 4 articles | Viewed by 6228 | Submission Open
Keywords: reproduction; oxidative stress; ROS; pregnancy
Algal Antioxidants: Physiology, Metabolism, and Evolution
edited by
submission deadline 31 Dec 2026 | 3 articles | Viewed by 4871 | Submission Open
Keywords: algae; antioxidant; oxidative stresses; algal physiology
Innovative Processing Technologies and Their Effects on Antioxidant Activity in Plant-Derived Natural Products
edited by
submission deadline 31 Dec 2026 | 6 articles | Viewed by 4683 | Submission Open
Keywords: innovative extraction methodologies; natural antioxidants; oxidative stress modulations; cell-based and biochemical assays
(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)
Phenolic Profiling and Antioxidant Capacity of Natural Products submission deadline 31 Dec 2026 | 2 articles | Viewed by 4211 | Submission Open
Keywords: plant extracts; antioxidant capacity; phenolic profiling; stress oxidative diseases
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
Inhibition of Oxidative Stress and Related Signaling Pathways in Neuroprotection—3rd Edition submission deadline 31 Dec 2026 | 2 articles | Viewed by 3643 | Submission Open
Keywords: neuroprotection; neurotoxicity; antioxidative vs. prooxidative activity; antioxidant capacity; signaling pathways; redox metals; apoptosis; ferroptosis; cuproptosis; autophagy
(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)
Antioxidants Isolation and Characterization
edited by José Luis Todolí Torró and
submission deadline 31 Dec 2026 | 4 articles | Viewed by 3388 | Submission Open
Keywords: plant-derived antioxidants; polyphenols; flavonoids; carotenoids; phenolic acids; green extraction techniques; chromatographic and spectroscopic analysis; metabolomics; antioxidant activity evaluation; agro-industrial by-products valorization
(This special issue belongs to the Section Methods for Antioxidants Evaluation/Measurement)
Phenolics as Antioxidant Agents—2nd Edition
edited by
submission deadline 31 Dec 2026 | 3 articles | Viewed by 2718 | Submission Open
Keywords: antioxidants; bioactive compounds; oxidative stress; structure–activity relationships (SARs); sustainable extraction; green chemistry; therapeutic potential; in vitro and in vivo models; food and biomedical applications
(This special issue belongs to the Section Natural and Synthetic Antioxidants)
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