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Antioxidants publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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NADPH Oxidases in Health and Aging—2nd Edition

edited by Marschall S. Runge and

Nageswara R. Madamanchi

submission deadline 30 Sep 2025 | 1 articles | Viewed by 4598 | Submission Open

Keywords: redox signaling; NADPH oxidases; reactive oxygen species (ROS); aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Bioactive Antioxidants from Agri-Food Wastes

edited by

Mia Kurek

and

Sabina Galus

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3745 | Submission Open

Keywords: agri-food byproducts; waste; food industry; additives; packaging

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Oxidative Stress in Livestock and Poultry—3rd Edition

edited by

Wutai Guan

and

Shihai Zhang

submission deadline 30 Sep 2025 | 4 articles | Viewed by 3154 | Submission Open

Keywords: oxidative stress; environmental stressors; gut microbiome; antioxidant strategies; epigenetic modifications

Oxidative/Nitrosative Stress in Cardiovascular Diseases

edited by

Claudia Penna

and Saveria Femminò

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3054 | Submission Open

Keywords: oxidative stress; cardiovascular disease; therapeutic approaches; biomarkers; exercise; aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Polyphenol-Lipid Interactions in Nutrition and Health

edited by

Ana Reis

and

Maarit Karonen

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2186 | Submission Open

Keywords: antibiotic resistance; animal feed; mouthfeel perception; bacterial growth; blood brain barrier; flavonoids; hydrolysable tannins; infection; (neuro)inflammation; microbial metabolites; nitric oxide; plant-based diets; phytochemicals; proanthocyanidins; vascular health

Oxidative Stress and NRF2 in Diabetes

edited by

R. Paul Robertson

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1617 | Submission Open

Keywords: oxidative stress; NRF2; ROS; diabetes; diabetes-related complications; insulin

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Age-Related Diseases

edited by

Gloria Olaso-Gonzalez

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1537 | Submission Open

Keywords: aging; age-related diseases; frailty; oxidative stress; reductive stress; redox homeostasis; antioxidants

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress During Physical Activity

edited by

Ivan Dimauro

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1401 | Submission Open

Keywords: physical activity; exercise; oxidative stress; reactive oxygen species (ROS); redox balance; cellular damage; skeletal muscle

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Exploring Plant-Derived Bioactive Compounds: The Role of Peptides, Polysaccharides, and Antioxidants in Nutriceutical Development and Health Promotion

edited by

Zhaohui Xue

submission deadline 30 Sep 2025 | 2 articles | Viewed by 915 | Submission Open

Keywords: plant-derived bioactive peptides; polysaccharides; structure– activity relationship (SAR); molecular mechanisms; oxidative stress; hypolipidemic effects; antitumor capacity; apoptosis induction

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

New Insight into Redox Homeostasis and Oxidative Stress in Health and Disease: Focus on Cardiac and Vascular Function

edited by

István Szokodi

and

Endre Sulyok

submission deadline 30 Sep 2025 | 1 articles | Viewed by 838 | Submission Open

Keywords: reactive oxygen/nitrogen species; oxidative/nitrosative stress; redox signaling; atherosclerosis; hypertension; stroke; myocardial infarction; heart failure; biomarker; translational and precision medicine

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Novel Antioxidant Mechanisms for Health and Diseases, 2nd Edition

edited by Yoshihisa Koyama

submission deadline 30 Sep 2025 | 1 articles | Viewed by 386 | Submission Open

Keywords: antioxidant therapy; reactive oxygen species; oxidative stress; nano-antioxidant therapy; nutrigenomics; microbiome

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidant Activity of Grape and Grape By-Products

edited by

Cristiana Radulescu

and Radu Lucian Olteanu

submission deadline 30 Sep 2025 | Viewed by 191 | Submission Open

Keywords: antioxidants; grapes and grape by-products; extracts; cosmetic formulations; chromatography; microencapsulation; phytochemical profile; microbiological assay

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Antioxidants and Their Application and Role in Bakery Products

edited by

Urszula Krupa-Kozak

and

Małgorzata Starowicz

submission deadline 30 Sep 2025 | Viewed by 122 | Submission Open

Keywords: antioxidants; antioxidant activity; phenolic compounds; vitamins; cereal-based conventional and gluten-free bakery products; plant-based by-products; fruits and vegetables; herbs; functional foods; health-related potential

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Optimizing Physical Exercise: Post-Exercise Recovery, Oxidative and Nitrosative Stress, and the Role of Physical Activity in Healthy Aging and Neuroprotection

edited by

Celestyna Mila-Kierzenkowska

and

Marta Pawlowska

submission deadline 30 Sep 2025 | Viewed by 107 | Submission Open

Keywords: oxidative stress; exercise; nitrosative stress; post-exercise damage; post-exercise regeneration; aging; neuroprotection

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Skin Disorders: Therapeutic Potential of Antioxidants

edited by

Hideya Ando

submission deadline 30 Sep 2025 | Viewed by 106 | Submission Open

Keywords: ultraviolet radiation; reactive oxygen species; oxidative stress; skin disorders; skin aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Plant Polyphenols in Human Health: Emerging Insights for Future Therapeutic Strategies

edited by

Vicente Micol

and

Francisco Javier Álvarez-Martínez

submission deadline 30 Sep 2025 | Viewed by 97 | Submission Open

Keywords: polyphenols; antioxidant properties; anti-inflammatory effects; metabolic stress; chronic disease prevention; gut microbiota; polyphenols metabolites; bioavailability; skin health; novel therapies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Women’s Special Issue Series: Antioxidants in Human Health—2nd Edition

edited by

Simone Van Breda

and

Ruth Edge

submission deadline 30 Sep 2025 | Viewed by 95 | Submission Open

Keywords: oxidative stress; reactive oxygen species (ROS); antioxidants; vitamins; phytochemicals; molecular mechanisms; non-communicable diseases; human health; aging; clinical and public health applications

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Reactive Oxygen Species Signalling and Oxidative Stress in Fish

edited by Daniela Vallone and

Nicholas S. Foulkes

submission deadline 30 Sep 2025 | Viewed by 88 | Submission Open

Keywords: ROS; toxicology; fish; zebrafish; metabolism; immunity; cell signalling

Inflammation and Oxidative Stress in Articular Cartilage

edited by

Carmelita G. Frondoza

submission deadline 30 Sep 2025 | Viewed by 85 | Submission Open

Keywords: cartilage; chondrocyte; joint inflammation; arthritis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Therapeutic Potential of Natural Antioxidants in Respiratory Diseases and Airway Inflammation

edited by Yo-Han Han

submission deadline 30 Sep 2025 | Viewed by 66 | Submission Open

Keywords: natural product; acute/chronic lung injury; inflammation; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Antioxidants and Oxidative Stress in Skin Health and Diseases

edited by

Yong Chool Boo

and

An Sang Mi

submission deadline 30 Sep 2025 | Viewed by 49 | Submission Open

Keywords: antioxidants; oxidative stress; skin health; skin disease; skin aging; cosmetics; dermatology; ultraviolet radiation; air pollution; glycation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Bioactive Compounds in Functional Foods and Their Role in Combating Oxidative Stress

edited by

Luana Izzo

Alessandra Cimbalo

and Massimo Frangiamone

submission deadline 20 Oct 2025 | 2 articles | Viewed by 6149 | Submission Open

Keywords: bioactive compounds; functional foods; polyphenols; flavonoids; carotenoids; vitamins

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Redox Regulation in Inflammation and Disease—3rd Edition

edited by

Eva-Maria Hanschmann

, Mariana Ines Holubiec and

Christoph Hudemann

submission deadline 20 Oct 2025 | 1 articles | Viewed by 899 | Submission Open

Keywords: redox signaling; reactive oxygen and nitrogen species; inflammation; signal transduction; thiol switches; regulation of immune cells; translational immunology

Antioxidant Peptides

edited by

Daniel Carneiro Moreira

and

José Roberto de Souza de Almeida Leite

submission deadline 30 Oct 2025 | Viewed by 115 | Submission Open

Keywords: structure– activity relationships; novel natural or synthetic sources; advanced delivery systems; roles in preventing or alleviating oxidative stress-related diseases.

Potential Health Benefits of Dietary Antioxidants

edited by

Irene Dini

submission deadline 31 Oct 2025 | 9 articles | Viewed by 30952 | Submission Open

Keywords: food antioxidants; food supplements; antioxidant activity; food antioxidant isolation; food antioxidant characterization; analytical method validation; antioxidant bioavailability; circular economy; sustainability

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Regulatory Effects of Curcumin, 2nd Edition

edited by

Jean-Marc Zingg

Kiyotaka Nakagawa

and

Taiki Miyazawa

submission deadline 31 Oct 2025 | 4 articles | Viewed by 18401 | Submission Open

Keywords: curcumin; antioxidant; prooxidant; bioavailability; bioactivity

Oxidative Stress and Liver Disease

edited by Alejandra Espinosa Escalona

submission deadline 31 Oct 2025 | 8 articles | Viewed by 13988 | Submission Open

Keywords: oxidative stress; antioxidants; MAFLD; NAFLD; obesity

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress as a Therapeutic Target of Alzheimer’s Disease

edited by

Marcello Leopoldo

and

Leonardo Brunetti

submission deadline 31 Oct 2025 | 6 articles | Viewed by 13557 | Submission Open

Keywords: Alzheimer's disease; neuroinflammation; therapeutic agent; oxidative stress

Antioxidant Role of High-Density Lipoprotein

edited by Paul Durrington

submission deadline 31 Oct 2025 | 8 articles | Viewed by 12450 | Submission Open

Keywords: lipoprotein oxidation; cell membrane oxidation; HDL antioxidant activity; glycosylation; atherosclerosis

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress Induced by Air Pollution, 2nd Edition

edited by

Yasuhiro Yoshida

submission deadline 31 Oct 2025 | 5 articles | Viewed by 8469 | Submission Open

Keywords: particulate matter; air pollution; oxidative stress; reactive oxygen species; inflammation

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Reactive Oxygen Species and Growth Factors in Photodynamic Therapy (PDT), Photobiomodulation (PBM), and Radiation Therapy (RT)

edited by Timothy C. Zhu and Brian C. Wilson

submission deadline 31 Oct 2025 | 4 articles | Viewed by 6199 | Submission Open

Keywords: reactive oxygen species (ROS); singlet oxygen (SO); radiation; photodynamic therapy; cancers

(This special issue belongs to the Section ROS, RNS and RSS)

Anti-Cancer Potential of Plant-Based Antioxidants

edited by

Javier Espino

María Garrido

and

Jonathan Delgado-Adamez

submission deadline 31 Oct 2025 | 5 articles | Viewed by 5876 | Submission Open

Keywords: cancer; antitumor activity; medicinal plants; natural antioxidants; polyphenols; terpenoids; carotenoids

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Inflammation in Bone Metabolism and Diseases

edited by

Jin Kyeong Choi

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4687 | Submission Open

Keywords: oxidative stress; immune system; inflammation; joint inflammation; bone; metabolism pathways

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Green Extraction of Antioxidant from Natural Source

edited by

Jolanta Flieger

submission deadline 31 Oct 2025 | 5 articles | Viewed by 4663 | Submission Open

Keywords: green extraction techniques ; supercritical fluid extraction ; ionic liquid (IL)-based extraction; microwave-assisted extraction; antioxidants; plants; cosmetic formulation

Antioxidant Activities of Phytochemicals in Fruits and Vegetables

edited by

Wen Qin

submission deadline 31 Oct 2025 | 3 articles | Viewed by 4211 | Submission Open

Keywords: ROS and oxidative stress; green and efficient extraction technology of phytochemicals; antioxidant activity of phytochemicals in fruits and vegetables; polyphenols and polysaccharides in fruits and vegetables; phytochemicals and inflammation

(This special issue belongs to the Section Natural and Synthetic Antioxidants)

Implication of Oxidative Stress in Promoting Cellular Senescence and Associated Pathologies—2nd Edition

edited by

Alexandra Barbouti

submission deadline 31 Oct 2025 | 3 articles | Viewed by 3642 | Submission Open

Keywords: oxidative stress; free radicals; reactive oxygen species (ROS); cellular senescence; ageing; age-related pathologies

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

The Role of Natural Antioxidants in Fruits and Vegetables in Human Health

edited by

Antonio Barberis

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3378 | Submission Open

Keywords: antioxidants; anti-inflammation; oxidative stress; fruits; vegetables; oxidation reactions; functional foods

Valorization of Waste Through Antioxidant Extraction and Utilization

edited by

Andrés Moreno

submission deadline 31 Oct 2025 | 3 articles | Viewed by 3349 | Submission Open

Keywords: valorization; waste management; green extraction; antioxidants; value-added products; by-products

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Heme Oxygenase in Health and Disease: New Insights and Future Directions

edited by

J. Catharina Duvigneau

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2855 | Submission Open

Keywords: enzyme activity; ferroptosis; carbon monoxide; oxidative stress; reactive oxygen and nitrogen species; heme proteins; heme degradation; heme responsive elements; heme regulation

(This special issue belongs to the Section Antioxidant Enzyme Systems)

Cellular ROS and Antioxidants: Physiological and Pathological Role—2nd Edition

edited by

Andrey V. Kozlov

Mihály Boros

and

Salvatore Nesci

submission deadline 31 Oct 2025 | 4 articles | Viewed by 1788 | Submission Open

Keywords: reactive oxygen and nitrogen species; intracellular signaling; oxidative stress; iron metabolism; mitochondrial dysfunction; hypoxia; inflammation; targeted and untargeted antioxidants; gas messengers natural and artificial sources of reactive oxygen species; antioxidant defense systems; small signaling molecules; oxidative stress-driven processes

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Phytochemicals Against Oxidative Stress: Polypharmacological Strategies for Aging-Related Disease

edited by

and

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1787 | Submission Open

Keywords: phytochemicals; antioxidants; systems biology; oxidative stress; hair loss; skin aging

Olive Antioxidants: Extraction, Biological Activity and Practical Applications—3rd Edition

edited by

Juan Fernández-Bolaños

and

Alejandra Bermudez-Oria

submission deadline 31 Oct 2025 | 2 articles | Viewed by 939 | Submission Open

Keywords: antioxidant effect; olive oil; olive by-products; olive leaves; polyphenols; carotenoids; polysaccharide– polyphenol complexes; vitamin E; health; Mediterranean diet

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

Unveiling the Essential Role of Coenzyme Q in Health

edited by

Guillermo López Lluch

and

Steen Larsen

submission deadline 31 Oct 2025 | Viewed by 565 | Submission Open

Keywords: coenzyme Q10; CoQ biosynthesis; ROS; cognitive deficiency; cardiovascular disease

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress Induced by Micro(Nano)plastics

edited by

Lavinia Casati

Alessandro Villa

and

Marco Parolini

submission deadline 31 Oct 2025 | 1 articles | Viewed by 488 | Submission Open

Keywords: micro(nano)plastics; oxidative stress; One Health; in vitro and in vivo models; organisms; cellular microenvironment

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress and Sperm: Technical, Biological and Clinical Aspects—2nd Edition

edited by

Monica Muratori

submission deadline 31 Oct 2025 | Viewed by 249 | Submission Open

Keywords: male infertility; ROS; oxidative sperm DNA damage; sperm DNA fragmentation; sperm epigenetic damage; assisted reproductive techniques; in vitro sperm manipulation; antioxidants; embryo development; pregnancy

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

From Waste to Health: Upcycling Agrifood By-Products into Functional Antioxidant-Rich Ingredients and Products

edited by

Ítala Marx

and

Feliciano Priego-Capote

submission deadline 31 Oct 2025 | Viewed by 196 | Submission Open

Keywords: antioxidant activity; oxidative stress; reactive oxygen species; polyphenols; bioactive compounds; functional ingredients; health-promoting formulations; agrifood waste; green extraction technologies; emerging analytical methods

Applications and Health Benefits of Novel Antioxidant Biomaterials—2nd Edition

edited by

Washington Luiz Esteves Magalhães

and Tielidy Lima

submission deadline 31 Oct 2025 | Viewed by 189 | Submission Open

Keywords: antioxidant biomaterials; tissue regeneration; biocompatibility; controlled release; premature aging

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Oxidative Stress in Respiratory Diseases—Second Edition

edited by

Sabina Galiniak

and

Stephen M. Black

submission deadline 31 Oct 2025 | Viewed by 160 | Submission Open

Keywords: reactive oxygen species; inflammation; antioxidant therapy; chronic obstructive pulmonary disease; asthma; cystic fibrosis; nitrosative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Modulation of Gut Microbiota and Oxidative Stress to Counteract or Prevent Human Disease

edited by

Simone Carradori

Annalisa Chiavaroli

Alessandra Ammazzalorso

and

Marialucia Gallorini

submission deadline 31 Oct 2025 | Viewed by 137 | Submission Open

Keywords: medicinal chemistry; enzyme modulators; neurodegenerative disorders; microbiota; gut– brain axis; inflammation; probiotic metabolomics; prebiotics; postbiotics; oxidative stress

(This special issue belongs to the Section Health Outcomes of Antioxidants and Oxidative Stress)

Plants and Plant-Based By-Products as Valuable Sources of Antioxidants: Current Tendencies and Achievements in Their Exploitation

edited by Svetlana Momchilova and

Adriana Slavova-Kazakova

submission deadline 31 Oct 2025 | Viewed by 122 | Submission Open

Keywords: antioxidants; oxidative stability; antioxidant activity; lipid oxidation; green chemistry; biomass; plants and by-products; herbs; utilization

(This special issue belongs to the Section Extraction and Industrial Applications of Antioxidants)

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