31 October 2026
Background: Body composition may be associated with the expression of cardiorespiratory fitness, particularly when peak oxygen uptake (VO2peak) is normalized to body mass or lean mass. This exploratory, cross-sectional, single-center study primarily...
Background: Thermal oxidation of edible oils generates lipid oxidation products that contribute to dyslipidemia, oxidative stress, and vascular injury. Estrogen deficiency further increases susceptibility to cardiovascular dysfunction. This study eva...
Clinical assessment commonly relies on physiological variables interpreted as isolated values or against population-derived thresholds. Although indispensable, these approaches provide limited information about regulatory flexibility, inter-system co...
Background/Objectives: Valsartan/sacubitril improves outcomes in heart failure, but its effects on cardiac performance in chronic hypertension remain unclear. We investigated the effects of chronic valsartan/sacubitril treatment on hemodynamics, card...
Purpose: This exploratory cross-sectional study examined associations between generalized joint hypermobility (GJH), physical performance, and ankle mobility in physically active young adults. Methods: Forty university students (28 males and 12 femal...
Objective physical-function assessment may help personalize supportive care across chimeric antigen receptor (CAR) T-cell therapy, yet rehabilitation evidence remains dispersed. We narratively synthesized adult hematologic CAR T-cell reports identifi...
Low back pain is a major cause of disability and is increasingly recognized as a multifactorial condition involving complex inflammatory and neuroimmune mechanisms. Inflammatory biomarkers may provide insight into the biological processes underlying...
Background/Objectives: This study investigated the preventive effects of apilarnil (APL) against copper nanoparticle (CuNPs)-induced liver and kidney injury in rats. Methods: Thirty-five rats were randomly allocated into five groups (n = 7): Control...
Cardiac autonomic recovery after exercise is conventionally summarized as a single nocturnal heart rate variability (HRV) average, treating sleep as a passive backdrop rather than an active determinant of recovery. Three distinct levels of inference...
Background/Objective: Bone is a mechanically responsive tissue whose trabecular microarchitecture adapts to local functional loading. Whether the presence of an unerupted, unilateral, vertically impacted mandibular third molar is associated with dete...
Background: Multicomponent exercise promotes healthy aging, but evidence in community-dwelling older women remains limited. This study examined pre–post changes in functional fitness and cardiovascular health following participation in a six-mo...
Background/Objectives: Firefighters may be at an elevated risk for cardiovascular disease due to occupational stressors, including shift work, overnight emergency responses, and sleep disruption. This cross-sectional pilot study conducted within a si...
Background/Objectives: Human physiological evidence for functional clothing is limited, and garment changes may reflect ordinary material or measurement effects. We described surface-temperature and heart rate variability (HRV) observations before an...
Background/Objectives: Inter-brain synchronization (IBS) has emerged as a key indicator of social cognition, reflecting the temporal alignment of neural activities across individuals. This systematic review aimed to determine the neurophysiological m...
Background: Changes in estrogen and progesterone during the menstrual cycle could potentially influence standing-induced hemodynamic and autonomic responses. Aims and Objectives: We aimed to explore the effects of menstrual cycle phases on cardiovasc...
Background/Objectives: Previous studies have shown that excess body weight influences plantar pressure. However, the specific impact of Body Mass Index (BMI) on dynamic pressure distribution during different phases of walking, as well as its effect o...
Background/Objectives: Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD) is a frequent complication of chronic kidney disease, characterized by altered bone mineral density and mineral–hormonal metabolism. Therapeutic exercise ma...
Background: Secondary multiple organ dysfunction syndrome (MODS) has an excessively high fatality rate. The mechanisms by which sepsis and systemic inflammatory response syndrome (SIRS) induces organ dysfunction and their characteristic pathological...
Objective: This study investigated the effects of three chronic stress exposure models (permanent elimination, forced swimming, and food and water deprivation) on bone oxidative stress, structure, and metabolism in vivo. Methods: Adult rats were expo...
Calcium (Ca2+) and magnesium (Mg2+) are essential divalent cations whose homeostasis is essential for cardiovascular, muscular and metabolic function. Absolute or relative imbalances between Ca and Mg can lead to cardiovascular, metabolic and neurolo...
Background/Objectives: Caffeine is a widely used ergogenic aid; however, evidence regarding its effects on neuromuscular and metabolic responses during resistance training remains limited. Therefore, this study aimed to analyze the effects of caffein...
Objective: The purpose of this exploratory study was to examine mean differences, reliability, and agreement between CP and W′ derived from a 3MAT performed after an ICT and values obtained during a standalone 3MAT performed on a separate day....
Background: Exercise adaptation is increasingly recognized as an immunometabolic process driven by coordinated interactions among inflammatory signaling, mitochondrial regulation, metabolic homeostasis, and recovery-associated physiology. Within this...
Congenital heart defects represent prevalent malformations requiring complex surgical interventions. Outcomes are influenced by clinical severity, inflammatory response, and complexity of care, highlighting the need for improved risk stratification t...
The open access journal Physiologia [...]
Background: The regulation of inorganic phosphate (Pi) homeostasis is predominantly mediated by the Pi transporters belonging to the SLC34 and SLC20 families of solute carriers. However, not all Pi handling can be explained by these transporters. In...
Background/Objectives: Chronic ethanol consumption damages erythrocyte membranes, reducing their deformability and disrupting erythropoiesis. Dopaminergic signalling plays an important role in regulating haematopoietic stem cells. However, the impact...
Background: Youth with type 1 diabetes (T1D) often show low physical activity levels and a long time spent in sedentary and poor sleep, which may worsen their health. This study aimed to describe baseline movement and sleep patterns in children and a...
Background/Objectives: This study evaluated carotid baroreflex sensitivity (cBRS) during graded exercise tests to exhaustion in healthy individuals. It aimed to elucidate whether the augmented blood pressure response during heavy- and maximal-intensi...
Background/Objectives: The combined effects of aerobic exercise and normobaric hyperoxia exposure on skeletal muscle in diabetes mellitus (DM) remain unclear. This study investigated whether their combination influences skeletal muscle capillary and...
Background/Objectives: This study examined the effects of an eight-week plyometric training programme on jump biomechanics, field-based jump performance, and repeated-jump endurance in 13–14-year-old volleyball players, and explored training-in...
Background/Objectives: Metabolic syndrome (MetS) is a cluster of cardiometabolic risk factors that increases the risk for cardiovascular disease. Although gait impairments are documented in older adults with MetS, few studies have examined gait biome...
Background: Childhood cancer survivors commonly experience long-term treatment effects that impair physical function. Access to in-person physical fitness assessments is often limited by geographic, logistical, and resource constraints. Virtually sup...
The purpose of this narrative review was to describe the maximal strength, muscle power, rate of force development, and muscle morphology of athletes across different ski disciplines. Specifically, this review synthesizes evidence on upper- and lower...
Objective: Analyze physical fitness variables and body composition to define patterns or similarities in performance using principal component analysis. Materials and Methods: Sixty-eight players participated in the study, divided into three groups a...
Background/Objectives: This systematic review examined whether oral vitamin D supplementation improves vitamin D status, health, and exercise outcomes in indoor-training aquatic athletes. Methods: We systematically reviewed randomized, placebo-contro...
Background/Objectives: To develop and internally validate multiple linear regression models to predict estimated VO2max from anthropometric variables and easily obtainable physical fitness tests in active university students and to compare model perf...
Background: The number of people working in Antarctica has steadily increased. Identifying the characteristic functional changes in polar expeditioners can help preserve health, enhance work capacity, and improve adaptive potential in specific enviro...
Background: Contemporary aneurysm surgery increasingly requires the management of complex lesions with limited physiological reserve. A growing “physiology-first” paradigm emphasizes that optimizing cerebrovascular dynamics during aneurys...
Background: As Para-Powerlifting (PP) athletes need the maximum bench press concentric strength performance during competitions, the velocity of the eccentric phase could be critical to the sport’s success. Methods: Through eccentric tempo modi...
Excess post-exercise oxygen consumption (EPOC) reflects cardiorespiratory fitness, energy metabolism and the residual physiological effects of preceding exercise. We aimed to compare EPOC profiles of master swimmers across different age groups and pe...
Objectives: The study aimed to comprehensively assess the impact of tattoos on the structural and functional properties of the skin in healthy women. Methods: The investigation included 22 female participants aged 19–41 years, covering a total...
Menopause is a natural biological transition marked by the cessation of regular menstrual cycles and is associated with significant endocrine, hormonal, and metabolic changes. Sleep disturbances are among the most common and distressing symptoms duri...
Background: Zearalenone (ZEA) is a potent estrogenic mycotoxin that adversely affects the female reproductive system, causing hormonal imbalance, uterine enlargement, structural changes in the reproductive tract, and reduced fertility. This study eva...
Background: Hydration and electrolyte strategies are critical in mountain ultra-endurance events, yet field-based evidence from trail races remains limited. This study examined the relationship between fluid intake, sodium consumption, and body mass...
Quantifying oxidative, glycolytic, and phosphagen energy system contributions during exercise is challenging due to their simultaneous activation and reliance on indirect estimation. This narrative review critically examines the methodological founda...
Background: Prenatal cannabinoid exposure (PCE) causes neurodevelopmental impairments affecting learning and memory; however, the receptor-level interactions underlying these cognitive deficits remain poorly understood. This study investigated whethe...
Introduction: cigarette smoking is a major source of systemic oxidative stress and a well-established risk factor for cardiovascular disease. Heated tobacco products (HTPs) are increasingly promoted as reduced-risk alternatives, yet their cellular ef...
Background/Objectives: Despite increasing interest in high-intensity exercise and cerebrovascular function, the effects of maximal sprint exercise on cerebrovascular reactivity (CVR), a key indicator of vascular health, remain unclear. Methods: This...
Background: Anthropometric characteristics are known determinants of rowing performance, particularly during adolescence, when rapid physical growth affects strength, leverage, and movement efficiency. Understanding how body size and proportionality...
