Skip to Content
You are currently on the new version of our website. Access the old version .

Chemosensors, Volume 14, Issue 2

2026 February - 24 articles

Cover Story: Aberrant glycosylation is related to several diseases, making glycoproteins and their glycoforms useful biomarkers. This review focuses on electrochemical strategies developed to assess the glycosylation level of a specific glycoprotein or biological structure (cells and tissues) rather than merely glycoprotein or cell concentration. Applications span diabetes management, congenital disorders of glycosylation, cancer prognosis, and neurodegenerative disease diagnosis. Innovative designs incorporate microfluidic and paper-based platforms for faster, low-cost analysis. Overall, electrochemical sensors hold significant potential for point-of-care testing, enabling the rapid and accurate evaluation of glycosylation status, with the potential to drive cell-based biomarker discovery and disease diagnostics. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (24)

  • Article
  • Open Access
1,024 Views
16 Pages

The analysis of intact phosphine ligands and phosphino organometallic complexes by mass spectrometry is problematic due to the reactivity of phosphorous(III) leading to rapid oxidation and decomposition of the ligands and complexes. Traditionally, th...

(This article belongs to the Special Issue Spectroscopic Techniques for Chemical Analysis)
  • Article
  • Open Access
906 Views
13 Pages

Coptisine Chloride: A Natural Isoquinoline Alkaloid as a Dual-Responsive Aggregation-Induced Emission Sensor for Heparin and Protamine

  • Nana Ma,
  • Xueling Dong,
  • Ruinan Li,
  • Chuang Du and ,
  • Yawen Wang,
  • Jiaxin Bai,
  • Run Ran,
  • Xulin Liu,
  • Dianshuo Zhang and
  • Haikui Zou
  • + 5 authors+ 0 author

Heparin (Hep) and its clinical antidote protamine (PRO) play essential yet antagonistic roles in anticoagulant therapy, necessitating reliable analytical tools to monitor their levels and interactions. Herein, we report that coptisine chloride (COP),...

(This article belongs to the Section Optical Chemical Sensors)
  • Article
  • Open Access
1,299 Views
16 Pages

Dynamic Characteristics of Primary and Secondary Polar Metabolites in Cabernet Sauvignon Grapes at Different Growth Stages in the Ningxia Wine Region

  • Feng-Lian Ma,
  • Jia-Nan Wang,
  • Xue-Teng Guo,
  • Hang Lv and ,
  • Jia-Jia Fan,
  • Gui-Juan Ma,
  • Li-Hua Tang,
  • Yi Lv and
  • Yong-Jie Yu
  • + 4 authors+ 0 author

This study focuses on the Helan Mountain East Foothills region of Ningxia, a typical continental climate wine-growing area, with Cabernet Sauvignon grapes as the subject. It combines trimethylsilyl derivatization–Gas Chromatography–Mass S...

(This article belongs to the Special Issue GC, MS and GC-MS Analytical Methods: Opportunities and Challenges (Fourth Edition))
  • Review
  • Open Access
7 Citations
2,671 Views
28 Pages

Integrating environmental sustainability into chemical sensor research is no longer optional and must be addressed at the laboratory scale, where material selection, fabrication strategies, and end-of-life management are defined. Although chemical se...

(This article belongs to the Special Issue Feature Review Papers in Chemical/Bio-Sensors and Analytical Chemistry in 2025)
  • Article
  • Open Access
3 Citations
1,515 Views
20 Pages

Diabetes continues to impose significant global health and economic burdens, driving the demand for robust, enzyme-free glucose sensors capable of reliable operation under physiological conditions. Here, we report the development of a high-performanc...

(This article belongs to the Section Electrochemical Devices and Sensors)
  • Article
  • Open Access
1 Citations
1,680 Views
15 Pages

Thermal Lens Vibrational Overtone Spectroscopy for Detection of Impurities in Liquid Alkanes

  • David Camejo,
  • Miguel Rodriguez-Escalante,
  • Parashu Nyaupane,
  • Helena Diez-y-Riega and
  • Carlos E. Manzanares

In this investigation, the local mode model for C-H overtone transitions in hydrocarbons and the thermal lens (TL) technique are used to obtain vibrational overtone spectra and subsequent analysis of hydrocarbon impurities in liquid solutions. The ex...

(This article belongs to the Special Issue Spectroscopic Techniques for Chemical Analysis)
  • Review
  • Open Access
7 Citations
3,285 Views
37 Pages

Advances in Electrochemical Aptasensors for Targeted Detection in Biomedicine, Food Safety, and Environmental Monitoring

  • Wenting Shang,
  • Peipei Zhou,
  • Mengxue Liu,
  • Guangxia Lv and ,
  • Mengqi Sun,
  • Yanxia Li and
  • Xiangying Meng
  • + 2 authors+ 0 author

Electrochemical biosensors have emerged as indispensable detection tools with rapid advancements in recent years, offering high sensitivity, specificity, and cost-effectiveness for quantifying diverse analytes, including amino acids, proteins, pathog...

(This article belongs to the Special Issue Recent Developments in Electrode Materials for Electrochemical Sensing)
  • Article
  • Open Access
4 Citations
1,657 Views
22 Pages

Eco-Friendly Nanocellulose Optical Chemosensor Immobilized with ADOL for Mercury Detection in Industrial Wastewater

  • Mohamed Abd-El Baset,
  • Nuha Y. Elamin,
  • Mohamed R. Elamin,
  • Soad S. Alzahrani and ,
  • Rasha M. Kamel,
  • Reda F. M. Elshaarawy and
  • Ahmed Shahat
  • + 2 authors+ 0 author

A novel chemosensor has been developed for the accurate and sensitive detection of Hg2+ ions in industrial wastewater. This sensor uses a stick-like nanocellulose architecture synthesized via a green method. The unique morphology and surface area of...

(This article belongs to the Section Optical Chemical Sensors)
  • Article
  • Open Access
1,915 Views
20 Pages

Roadside public transport stops represent localized air pollution hotspots where short-term exposure may differ substantially from levels reported by urban background monitoring. This study investigates the application of low-cost air quality sensors...

(This article belongs to the Section Nanostructures for Chemical Sensing)
  • Review
  • Open Access
3 Citations
2,469 Views
69 Pages

Nanostructure-Enhanced Optical Sensing Platforms for Pesticide Analysis in Food and Water Samples: A Review

  • Aurelia Magdalena Pisoschi,
  • Loredana Stanca,
  • Florin Iordache,
  • Iuliana Ionascu and ,
  • Iuliana Gajaila,
  • Ovidiu Ionut Geicu,
  • Liviu Bilteanu and
  • Andreea Iren Serban
  • + 3 authors+ 0 author

Pesticides are applied to promote performances in the agricultural field, sustaining crop productivity by counteracting the damages induced by pests and weeds. Under conditions of uncontrolled application, their negative influences exerted on soil, w...

(This article belongs to the Special Issue Feature Review Papers in Chemical/Bio-Sensors and Analytical Chemistry in 2025)
  • Article
  • Open Access
4 Citations
2,436 Views
18 Pages

Green Synthesis of ZnO Nanoparticles Using Retama raetam Leaf Extract for VOC Sensing Applications

  • Tarek Sekrafi,
  • Mosaab Echabaane,
  • Ahmadou Ly,
  • Marc Debliquy and ,
  • Chérif Dridi and
  • Driss Lahem
  • + 1 author+ 0 author

The green synthesis of zinc oxide nanoparticles (ZnO NPs) using Retama raetam leaf extract via microwave irradiation was investigated. The biosynthesized NPs were characterized using scanning electron microscopy (SEM), energy dispersive X-ray spectro...

(This article belongs to the Special Issue Chemical Sensors for Bio-Medical and Environmental Applications, 2nd Edition)
  • Article
  • Open Access
896 Views
11 Pages

In Situ Formation of Quantum Dots as a Novel Fluorescence Probe for Phosphate Anion Detection

  • Xiuhua You,
  • Zhijun Li,
  • Youjiao Wu,
  • Xinhua Ma and ,
  • Yiwei Wang,
  • Shurong Tang and
  • Wei Chen
  • + 2 authors+ 0 author

A new fluorescence detection method for PO43− was developed through the in situ synthesis of cadmium sulfide quantum dots (CdS QDs). Without PO43−, the CdS QDs could not be effectively formed by only the S2− and Cd2+ in the solution...

(This article belongs to the Section Applied Chemical Sensors)
  • Article
  • Open Access
6 Citations
2,587 Views
18 Pages

Heavy Metal Ion Detection by Carbonized Metal–Organic–Framework (MOF-C) Nanocomposite-Modified Electrochemical Sensors

  • Wei Wang,
  • Peiting Zhao,
  • Chenjie Wang,
  • Aixuan Xu and ,
  • Wei Ma,
  • Gan Wang,
  • Zehua Han,
  • Yishan Lu,
  • Jin Yan and
  • Ran Peng
  • + 5 authors+ 0 author

Efficient detection of heavy metal ions in complex marine environments is essential to the safety of marine organisms and human beings. This study developed a novel screen-printed-electrode (SPE) electrochemical sensor for rapid on-site determination...

(This article belongs to the Special Issue Advanced Nanomaterials-Based (Bio-)Sensors for Electrochemical Detection and Analysis: 2nd Edition)
  • Article
  • Open Access
2 Citations
1,501 Views
14 Pages

In this study, we present a new approach for detecting carbon dioxide based on the voltammetric behavior of selected pH indicators in a deep eutectic solvent (DES). The sensing strategy exploits the electrochemical oxidation potentials of acid–...

(This article belongs to the Special Issue Applications of Electronic Nose (E-Nose) and Electronic Tongue (E-Tongue) in Food Quality)
  • Review
  • Open Access
4 Citations
1,891 Views
33 Pages

Electrochemical Strategies to Evaluate the Glycosylation Status of Biomolecules for Disease Diagnosis

  • Roberto María-Hormigos,
  • Olga Monago-Maraña and
  • Agustin G. Crevillen

Aberrant glycosylation is linked to several diseases, making glycoproteins and their glycoforms promising biomarkers. Traditional methods like mass spectrometry offer high sensitivity but are costly, time-consuming, and unsuitable for point-of-care t...

(This article belongs to the Special Issue Feature Review Papers in Chemical/Bio-Sensors and Analytical Chemistry in 2025)
  • Article
  • Open Access
1 Citations
2,165 Views
18 Pages

Electrochemical Sensor Based on a Fe3O4 and Graphene Composite for the Detection of Myristicin

  • Dewi Murniati,
  • Deden Saprudin,
  • Irmanida Batubara,
  • Budi Riza Putra and
  • Utami Dyah Syafitri

This study aims to develop an electrochemical sensor based on a glassy carbon electrode (GCE) modified with Fe3O4 and graphene for the detection of myristicin as a characteristic compound in nutmeg plants. Electrode modification materials were prepar...

(This article belongs to the Special Issue (Bio)Chemical Sensing in Real-World Applications—a Dedicated Issue for Young Researchers)
  • Review
  • Open Access
4 Citations
2,883 Views
28 Pages

Multi-Way Data Analysis Nowadays: Taking Advanced Chemometric Tools to Everyday Analytical Chemistry Applications

  • Marta Guembe-Garcia,
  • Lisa Rita Magnaghi,
  • Guglielmo Emanuele Franceschi,
  • Antonio Bova and
  • Raffaela Biesuz

Multi-way analysis has become one of the most powerful and versatile chemometric approaches for dealing with the increasing complexity of data generated in modern analytical chemistry. Advances in instrumentation, the widespread use of hyphenated tec...

(This article belongs to the Special Issue Advanced Chemometric Methods for Analytical Applications)
  • Article
  • Open Access
1 Citations
1,369 Views
22 Pages

Untargeted Metabolomics and Multivariate Data Processing to Reveal SARS-CoV-2 Specific VOCs for Canine Biodetection

  • Diego Pardina Aizpitarte,
  • Eider Larrañaga,
  • Ugo Mayor,
  • Ainhoa Isla and ,
  • Jose Manuel Amigo and
  • Luis Bartolomé
  • + 1 author+ 0 author

The exceptional olfactory capabilities of trained detection dogs demonstrate high potential for identifying infectious diseases. However, safe and standardized canine training requires specific chemical targets rather than infectious biological sampl...

(This article belongs to the Special Issue Artificial Intelligence (AI)/Machine Learning (ML)-Assisted Chemical Sensors)
  • Article
  • Open Access
3 Citations
2,349 Views
20 Pages

Benchtop Volatilomics and Machine Learning for the Discrimination of Coffee Species

  • Catherine Kiefer,
  • Steffen Schwarz,
  • Nima Naderi,
  • Hadi Parastar and ,
  • Sascha Rohn and
  • Philipp Weller
  • + 1 author+ 0 author

The main characteristics of the large number of coffee species are differences in aroma and caffeine content. Labeled blends of Coffea arabica (C. arabica) and Coffea canephora (C. canephora) are common to broaden the flavor profile or enhance the st...

(This article belongs to the Special Issue GC, MS and GC-MS Analytical Methods: Opportunities and Challenges (Fourth Edition))
  • Review
  • Open Access
9 Citations
2,296 Views
30 Pages

Advances and Prospects of Chemiresistive Breath Humidity Sensors

  • Yiming Qiao,
  • Mingna Yang,
  • Siyu Rao,
  • Cong Ji and ,
  • Xuemin Duan,
  • Xiaomei Yang,
  • Shuai Chen and
  • Ling Zang
  • + 3 authors+ 0 author

Chemiresistive breath humidity sensors (CRBHSs) have emerged as a promising technology for non-invasive health monitoring, offering high sensitivity, a simple device architecture, strong miniaturization potential, and low power consumption. This revi...

(This article belongs to the Special Issue Feature Review Papers in Chemical/Bio-Sensors and Analytical Chemistry in 2025)
  • Article
  • Open Access
2,253 Views
16 Pages

Porous-Architecture-Driven Performance of Electrospun SnO2 Nanofibers for Reliable H2S Detection

  • Milica Počuča-Nešić,
  • Katarina Vojisavljević,
  • Slavica Savić Ružić,
  • Zorica Marinković Stanojević and ,
  • Aleksandar Malešević,
  • Tian Tian,
  • Nan Ma,
  • Rong Qian,
  • Mao Huang and
  • Zorica Branković
  • + 7 authors+ 2 authors

Pure SnO2 nanofibers were synthesized via an electrospinning method and subsequently calcined at 550 °C to investigate the structure–property relationship governing H2S gas sensing performance. X-Ray diffraction confirmed the formation of t...

(This article belongs to the Section Nanostructures for Chemical Sensing)
  • Article
  • Open Access
1 Citations
1,039 Views
18 Pages

Monitoring trace nitrophenol pollutants in water has garnered considerable attention. A porous organic polymer-modified cellulose nanofiber membrane (COP-99@DCA) was fabricated via in situ growth of a porous organic polymer on an electrospun cellulos...

(This article belongs to the Special Issue (Bio)Chemical Sensing in Real-World Applications—a Dedicated Issue for Young Researchers)
  • Review
  • Open Access
10 Citations
7,438 Views
28 Pages

Bioactive Peptides from Natural Sources: Biological Functions, Therapeutic Potential and Applications

  • Francisca Rodríguez-Cabello,
  • Lyanne Rodríguez,
  • Fanny Guzmán,
  • Basilio Carrasco and ,
  • Sigrid Sanzana,
  • Andrés Trostchansky,
  • Iván Palomo and
  • Eduardo Fuentes
  • + 3 authors+ 0 author

Natural bioactive peptides have emerged as pivotal candidates in modern science due to their multifaceted biological activities and versatile applications across biomedicine, biotechnology, and nutraceuticals. These molecules exhibit a broad pharmaco...

(This article belongs to the Special Issue GC, MS and GC-MS Analytical Methods: Opportunities and Challenges (Fourth Edition))
  • Article
  • Open Access
1,119 Views
20 Pages

Phytoremediation is an eco-friendly and in situ solution for remediating heavy metal-contaminated soils, yet practical application requires timely and accurate effectiveness evaluation. However, conventional chemical analysis of plant parts and soils...

(This article belongs to the Special Issue Application of Laser-Induced Breakdown Spectroscopy, 2nd Edition)
XFacebookLinkedIn
Chemosensors - ISSN 2227-9040