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Chemosensors
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Feature Review Papers in Chemical/Bio-Sensors and Analytical Chemistry in 2025
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Feature Review Papers in Chemical/Bio-Sensors and Analytical Chemistry in 2025

A special issue of Chemosensors (ISSN 2227-9040).

Deadline for manuscript submissions: 31 December 2025 | Viewed by 973

Special Issue Editors

Prof. Dr. Nicole Jaffrezic-Renault

E-Mail Website
Guest Editor
Institute of UTINAM, University of Franche-Comté, UMR-CNRS 6213, 16 Gray Road, 25030 Besançon, France
Interests: biosensors; gas sensing; biomedical and environmental applications
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Jin-Ming Lin

E-Mail Website
Guest Editor
Beijing Key Laboratory of Microanalytical Methods and Instrumentation, Department of Chemistry, Tsinghua University, Beijing 100084, China
Interests: bio- and environmental analytical chemistry; microfluidics and mass spectrometry for cell analysis; chemiluminescence/fluorescence immunoassay for protein and DNA analysis; analytical methods for negative oxygen ions and reactive oxygen species (ROS); sample pretreatment for mass spectrometry and chromatography analysis; development of analytical instrumentation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue aims to curate a collection of in-depth review papers encompassing comprehensive insights, analyses, and advancements in the field of chemical sensors, biosensors, and related analytical methods and systems. By selectively featuring review and systematic review manuscripts, this series aims to provide a rigorous and consolidated understanding of recent developments, offering valuable insights for researchers and practitioners in this field.

We sincerely welcome you all to contribute comprehensive review articles on a trending topic for peer review and possible publication.

Prof. Dr. Nicole Jaffrezic-Renault
Prof. Dr. Jin-Ming Lin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • electrochemical devices and sensors
  • biosensors and imaging
  • optical chemical sensors
  • gas sensors
  • material-based chemical sensors
  • analytical methods and applications

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Review

20 pages, 5758 KiB  
Review
Innovative Microfluidic Technologies for Rapid Heavy Metal Ion Detection
by Muhammad Furqan Rauf, Zhenda Lin, Muhammad Kamran Rauf and Jin-Ming Lin
Chemosensors 2025, 13(4), 149; https://doi.org/10.3390/chemosensors13040149 - 18 Apr 2025
Viewed by 325
Abstract
Heavy metal ion (HMI) contamination poses significant threats to public health and environmental safety, necessitating advanced detection technologies that are rapid, sensitive, and field-deployable. While conventional methods like atomic absorption spectroscopy (AAS) and inductively coupled plasma mass spectrometry (ICP-MS) remain prevalent, their limitations—including [...] Read more.
Heavy metal ion (HMI) contamination poses significant threats to public health and environmental safety, necessitating advanced detection technologies that are rapid, sensitive, and field-deployable. While conventional methods like atomic absorption spectroscopy (AAS) and inductively coupled plasma mass spectrometry (ICP-MS) remain prevalent, their limitations—including high costs, complex workflows, and lack of portability—underscore the urgent need for innovative alternatives. This review consolidates advancements in the last five years in microfluidic technologies for HMI detection, emphasizing their transformative potential through miniaturization, integration, and automation. We critically evaluate the synergy of microfluidics with cutting-edge materials (e.g., graphene and quantum dots) and detection mechanisms (electrochemical, optical, and colorimetric), enabling ultra-trace detection at parts-per-billion (ppb) levels. We highlight novel device architectures, such as polydimethylsiloxane (PDMS)-based labs-on-chip (LOCs), paper-based microfluidics, 3D-printed systems, and digital microfluidics (DMF), which offer unparalleled portability, cost-effectiveness, and multiplexing capabilities. Additionally, we address persistent challenges (e.g., selectivity and scalability) and propose future directions, including AI integration and sustainable fabrication. By bridging gaps between laboratory research and practical deployment, this review provides a roadmap for next-generation microfluidic solutions, positioning them as indispensable tools for global HMI monitoring. Full article
(This article belongs to the Special Issue Feature Review Papers in Chemical/Bio-Sensors and Analytical Chemistry in 2025)
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25 pages, 8266 KiB  
Review
Challenges and Applications of Bio-Sniffers for Monitoring Volatile Organic Compounds in Medical Diagnostics
by Yang Wang, Xunda Zhou, Siying Mao, Shiwei Chen and Zhenzhong Guo
Chemosensors 2025, 13(4), 127; https://doi.org/10.3390/chemosensors13040127 - 3 Apr 2025
Viewed by 392
Abstract
Bio-sniffers represent a novel detection technology that demonstrates significant potential in medical diagnostics. Specifically, they assess disease conditions and metabolic status through the detection of volatile organic compounds (VOCs) in exhaled breath. Unlike conventional methods such as gas chromatography-mass spectrometry (GC-MS) and gas [...] Read more.
Bio-sniffers represent a novel detection technology that demonstrates significant potential in medical diagnostics. Specifically, they assess disease conditions and metabolic status through the detection of volatile organic compounds (VOCs) in exhaled breath. Unlike conventional methods such as gas chromatography-mass spectrometry (GC-MS) and gas chromatography time-of-flight mass spectrometry (GC-TOF-MS), bio-sniffers provide rapid, sensitive, and portable detection capabilities. In this review, we examine the metabolic pathways and detection methods of specific VOCs in the human body, and their roles as disease biomarkers, and focus on the detection principles, performance characteristics, and medical applications of two bio-sniffer types: electrical and optical sensors. Finally, we systematically discuss the current challenges facing bio-sniffers in VOC monitoring, outline future development directions, and provide suggestions for improving sensitivity and reducing environmental interference. Full article
(This article belongs to the Special Issue Feature Review Papers in Chemical/Bio-Sensors and Analytical Chemistry in 2025)
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