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Chemosensors
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Advanced Nanomaterials-Based (Bio-)Sensors for Electrochemical Detection and Analysis: 2nd Edition
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Advanced Nanomaterials-Based (Bio-)Sensors for Electrochemical Detection and Analysis: 2nd Edition

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Electrochemical Devices and Sensors".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 2257

Special Issue Editors

Prof. Dr. Iolanda Cruz Vieira

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Guest Editor
Laboratory of Biosensors, Federal University of Santa Catarina, Florianópolis 88040-900, Brazil
Interests: nanostructured materials; green synthesis; microcystin; cardiac biomarkers; electrochemical immunosensors; enzymatic biosensors; laccase; peroxidase; phenolic compounds; pharmaceutical and food analysis
Special Issues, Collections and Topics in MDPI journals
Dr. Edson Roberto Santana

E-Mail Website
Guest Editor
Laboratory of Biosensors, Federal University of Santa Catarina, Florianópolis 88040-900, Brazil
Interests: electroanalytical chemistry; electrochemical sensors and biosensors; 3D printing of electrochemical devices; nanostructured materials for sensing applications; environmental monitoring of emerging pollutants
Special Issues, Collections and Topics in MDPI journals
Dr. João Paulo Winiarski

E-Mail Website
Guest Editor
Laboratory of Biosensors, Federal University of Santa Catarina, Florianópolis 88040-900, Brazil
Interests: nanomaterials; silica-based materials; 2D materials; multi-walled carbon nanotubes; organic-inorganic hybrid materials; biomarkers; environmental monitoring
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The rapid evolution of nanomaterials has significantly impacted the development of electrochemical (bio-)sensors, enabling devices with enhanced sensitivity, reproducibility, and lower detection limits. This Special Issue of Chemosensors aims to highlight innovative research that employs nanoparticles, conducting polymers, hybrid nanostructures, and biorecognition elements to expand the analytical capabilities of electrochemical platforms. Studies involving different electrode substrates, such as glassy carbon, screen-printed electrodes, boron-doped diamond, or 3D-printed composites, are of particular interest.

In addition to classical approaches, we welcome contributions that reflect current trends in this field, such as the integration of flexible and wearable devices, point-of-care and multiplexed detection systems, and sustainable green fabrication strategies. The use of advanced nanomaterials, including metal–organic frameworks (MOFs), MXenes, and other emerging hybrids, is also highly encouraged. Applications in clinical diagnostics, environmental monitoring, food safety, and pharmaceutical analysis are especially emphasized.

This Special Issue invites original research articles, critical reviews, and communications from interdisciplinary perspectives, aiming to provide a comprehensive overview of how advanced nanomaterials are reshaping the landscape of electrochemical (bio-)sensing.

Prof. Dr. Iolanda Cruz Vieira
Dr. Edson Roberto Santana
Dr. João Paulo Winiarski
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanoparticles
  • 2D materials
  • 3D materials
  • electrochemical (bio-)sensors
  • immunosensors
  • modified electrodes
  • electroanalysis
  • enzymes
  • polymers

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Related Special Issue

Published Papers (3 papers)

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Research

18 pages, 15012 KB  
Article
Construction and Application Study of a Non-Enzymatic Dopamine Sensor Based on Zinc Porphyrin–Chitosan-Functionalized Reduced Graphene Oxide
by Xiangyu Ren, Rundong Wang, Yiru Zhang, Mengjin Zhai, Yukun Qin, Wenhao Liao, Anjie Cao, Yuan Chen and Bingkai Han
Chemosensors 2026, 14(6), 127; https://doi.org/10.3390/chemosensors14060127 - 3 Jun 2026
Abstract
Metalloporphyrins play an important role in biomedicine, catalysis, and energy, among other fields, due to their structural complexity and functional diversity. In this study, GO was used as the precursor support and chitosan was employed to reduce and functionalize GO into chitosan-functionalized rGO. [...] Read more.
Metalloporphyrins play an important role in biomedicine, catalysis, and energy, among other fields, due to their structural complexity and functional diversity. In this study, GO was used as the precursor support and chitosan was employed to reduce and functionalize GO into chitosan-functionalized rGO. Furthermore, metalloporphyrins were covalently linked to the amino side chains of chitosan via an amide crosslinking method, and a series of metalloporphyrin–chitosan-functionalized rGO nanocomposites were designed and synthesized. A set of poly(metalloporphyrin–chitosan)-functionalized rGO working electrodes was constructed by drop-coating onto glassy carbon electrodes, and their electrocatalytic performance toward dopamine was investigated in PBS solution. Finally, zinc(II) porphyrin, with the best performance, was selected as the core catalytic unit to fabricate an enzyme-free dopamine sensor. Under optimal working conditions, the sensor exhibited a sensitivity of 0.30 mA mM−1cm−2, a linear detection range of 0.001~1.0 mM, and a low detection limit of 0.05 μM (S/N = 3). The sensor showed anti-interference ability against various interfering ions and electroactive substances, as well as good stability and repeatability. Full article
(This article belongs to the Special Issue Advanced Nanomaterials-Based (Bio-)Sensors for Electrochemical Detection and Analysis: 2nd Edition)
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19 pages, 3588 KB  
Article
A Novel Conductometric Methanol Sensor Based on Green-Synthesized Fe3O4-Nanoparticles
by Sabri Ouni, Eslam Elkalla, Sumera Khizar, Abdelhamid Elaissari, Abdelhamid Errachid and Nicole Jaffrezic-Renault
Chemosensors 2026, 14(4), 90; https://doi.org/10.3390/chemosensors14040090 - 3 Apr 2026
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Abstract
Methanol (MeOH) is widely used in industry and is highly toxic when ingested. In this work, a new micro-conductometric transducer is functionalized with magnetic Fe3O4 nanoparticles capped with Artemisia Herba Alba (AHA) extract. The resulting AHA-Fe3O4 nanoparticles, [...] Read more.
Methanol (MeOH) is widely used in industry and is highly toxic when ingested. In this work, a new micro-conductometric transducer is functionalized with magnetic Fe3O4 nanoparticles capped with Artemisia Herba Alba (AHA) extract. The resulting AHA-Fe3O4 nanoparticles, crystallized in the cubic spinel phase, exhibit an average crystallite size of 6 nm. These nanoparticles were homogeneously dispersed within an electrodeposited chitosan film on interdigitated electrodes for conductometric measurements. The gas-sensing behavior of the films was evaluated at room temperature toward methanol, ethanol, and acetone vapors. For methanol, the sensor shows response times (tRes) ranging from 9 to 12 s depending on the analyte concentration, with a detection limit of 600 ppm in the gas phase. The methanol sensor presents a sensitivity 30 times lower for acetone and 3.7 times lower for ethanol. The sensor exhibited stable detection sensitivity over two months, under intermittent storage at 4 °C. Methanol was detected in the headspace of commercial product samples, in good agreement with the producer’s value. Full article
(This article belongs to the Special Issue Advanced Nanomaterials-Based (Bio-)Sensors for Electrochemical Detection and Analysis: 2nd Edition)
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18 pages, 2976 KB  
Article
Heavy Metal Ion Detection by Carbonized Metal–Organic–Framework (MOF-C) Nanocomposite-Modified Electrochemical Sensors
by Wei Wang, Peiting Zhao, Chenjie Wang, Aixuan Xu, Wei Ma, Gan Wang, Zehua Han, Yishan Lu, Jin Yan and Ran Peng
Chemosensors 2026, 14(2), 40; https://doi.org/10.3390/chemosensors14020040 - 3 Feb 2026
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Abstract
Efficient detection of heavy metal ions in complex marine environments is essential to the safety of marine organisms and human beings. This study developed a novel screen-printed-electrode (SPE) electrochemical sensor for rapid on-site determination of typical heavy metal ions such as Cu2+ [...] Read more.
Efficient detection of heavy metal ions in complex marine environments is essential to the safety of marine organisms and human beings. This study developed a novel screen-printed-electrode (SPE) electrochemical sensor for rapid on-site determination of typical heavy metal ions such as Cu2+, Pb2+, Cd2+, and Hg2+ in seawater. The sensor employs a three-electrode system, with the working electrode modified with a composite of metal–organic framework-derived carbon (MOF-C) and multiwalled carbon nanotubes (MWCNTs), thereby significantly enhancing detection sensitivity and selectivity. By optimizing square-wave anodic stripping voltammetry (SWASV) parameters, detection limits of 0.83, 0.40, 1.05, and 0.30 μM for the detection of Cu2+, Pb2+, Cd2+, and Hg2+ ions were achieved. In mixed-ion detection, excellent peak separation and strong resistance to interferences were demonstrated. Experimental results demonstrate that the sensor exhibits good linear response, excellent interference resistance, and high practicality, providing a new approach for rapid on-site determination of heavy metal pollution in marine environments. Full article
(This article belongs to the Special Issue Advanced Nanomaterials-Based (Bio-)Sensors for Electrochemical Detection and Analysis: 2nd Edition)
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