Optical acquisition geometry determines the tissue regions represented in visible–near-infrared (Vis–NIR) spectra, yet its interactions with spectral preprocessing and multimodal fusion remain insufficiently understood for intact citrus f...
This work reports a novel, ultra-sensitive electroanalytical sensor based on a carbon paste electrode modified with multi-walled carbon nanotubes, cesium chloride, and sodium dodecyl sulfate (CPE/MWCNT-CsCl/SDS) for the determination of the antihista...
Semiconductors are regarded as promising alternatives to traditional noble metals for constructing surface-enhanced Raman scattering (SERS) substrates. Nevertheless, their sensitivity is insufficient for widespread practical applications. In this wor...
Prostate cancer is a neoplastic disease that generally remains asymptomatic until its late-stage emergence. Among the techniques approved to date for prostate cancer diagnosis, prostate-specific antigen (PSA) screening is the most established method...
1-Aminopyrene, as a transformation product of the priority pollutant 1-nitropyrene, has raised increasing concerns due to its carcinogenic, mutagenic, and bioaccumulative properties in marine environments. A rapid and sensitive method for trace 1-ami...
In this paper, we report a flow injection electrochemical sensor for bisphenol F based on a hierarchical multimodal nanoporous gold (hm-NPG)/multi-walled carbon nanotube (MWCNT) nanocomposite deposited onto a screen-printed carbon electrode (SPCE). T...
Intelligent gas sensors (IGSs) have garnered significant attention owing to their highly sensitive, selective, and reliable gas detection in industrial safety, environmental monitoring, food quality assessment, healthcare diagnostics, and smart Inter...
Paper-based colorimetric glucose sensing has evolved from simple visual assays toward digitally quantified systems increasingly supported by artificial intelligence (AI). However, advanced computational analysis cannot fully compensate for limitation...
Accurate monitoring of antidepressant drugs is essential for ensuring therapeutic efficacy and minimizing adverse effects, creating a demand for sensitive and reliable analytical methodologies. In the present study, a novel electrochemical sensor was...
Carbon dots (CDs) have emerged as widely used functional nanomaterials in biomedical sensing due to their tunable fluorescence emission wavelength, excellent biocompatibility, and ease of functional modification. Fluorescent CDs operating in the near...
The tumor microenvironment (TME) is spatially and temporally heterogeneous, limiting the specificity of single-biomarker strategies for resolving complex tumor states. The sequence programmability and predictable base pairing of DNA allow multiple bi...
Wine-processed Scutellaria baicalensis is a processed Chinese herbal product obtained by wine-processing of raw S. baicalensis. Flavonoids are its core pharmacodynamic constituents with heat-clearing, anti-inflammatory, hepatoprotective and other bio...
Porphyrins are typical macrocyclic conjugated compounds widely utilized for designing high-sensitivity and high-selectivity chemical sensors. Porphyrin macrocycles can self-assemble into uniform two-dimensional (2D) nanostructures on gold films via &...
Near-infrared spectroscopy supports rapid quantification of moisture, oil, protein, and starch in corn. Their prediction models may require different spectral inputs, complicating shared-variable selection. We developed the multicomponent shared wave...
The demand for non-destructive evaluation of agricultural products has stimulated the emergence of multimodal sensing technologies capable of integrating diverse quality- and safety-related information. Recent advances in multimodal sensing and machi...
Thiamethoxam is a widely used neonicotinoid insecticide in agriculture, and its excessive use has raised growing concerns about food safety and environmental pollution. In this study, a portable fluorescence sensing platform was developed for the rap...
Wearable health monitoring is expanding from physical signals, such as heart rate and body temperature, to molecular information at body interfaces and in biofluids. Raman spectroscopy provides chemically specific vibrational fingerprints and support...
Background: Astronauts operating in extravehicular activity (EVA) and intravehicular activity (IVA) suits are exposed to a closed, thermally demanding microenvironment in which sweat accumulation, hydration status, skin-barrier disturbance, optical-s...
Real-time detection of the six characteristic gases dissolved in transformer oil (H2, CO, CO2, CH4, C2H4, C2H2), present from sub-ppm levels for C2H2 to several thousand ppm for CO2, is essential for early fault diagnosis in oil-immersed power equipm...
Quinones have emerged as versatile optical signal transducers in spectroscopic analytical chemistry because of their unique redox activity, electron-transfer capability, reactive oxygen species generation, and tunable photophysical properties. Beyond...
Pt-functionalized SnO2 hollow nanotubular structures were fabricated by single-nozzle electrospinning followed by calcination and evaluated for H2S sensing. At an operating temperature of 350 °C, the 2 wt% Pt/SnO2 sensor exhibited a response of 5...
Electronic noses provide a pattern-based approach for investigating volatile profiles associated with colorectal cancer; however, the combined analysis of participant-matched sensor profiles from different biological matrices remains largely unexplor...
Addictive drug abuse remains a major global public health concern, creating a need for rapid and reliable approaches for drug screening and on-site analysis. Conventional analytical techniques provide accurate chemical identification but generally re...
Fluorescence imaging has emerged as a transformative tool in parasitological research, providing high-contrast visualization of complex morphologies often obscured in traditional bright-field microscopy. This review article synthesizes recent advance...
The sensing and detection of toxic and hazardous gases represents a critical technology in urgent need of development. Herein, density functional theory is employed to explore the adsorption characteristics and electronic response of CO2, CO, SO2, an...
Protein-based biosensors exploit the extraordinary selectivity of proteins toward specific ligands—such as other proteins, ions, and electromagnetic signals—often surpassing engineered recognition systems. Ligand binding induces structura...
Fluconazole (FLU) is a widely used antifungal drug, and its reliable determination is important for quality control in pharmaceutical analysis. This study aimed to develop a simple and accurate FLU-selective potentiometric sensor based on a molecular...
Knife crime has increased globally, yet the effectiveness of current detection methods used by law enforcement is often limited in operational settings. This challenge highlights the need for innovative detection approaches. The use of canines as hig...
A simple, low-cost analytical platform based on a commercial direct methanol–ethanol fuel cell (D(M–E)FC) combined with chemometric data analysis is investigated for the quantitative analysis and exploratory differentiation of pharmaceuti...
Herbal medicines (HMs) are chemically complex multi-component systems, yet analytical strategies that systematically connect chemical composition, biological activity, target prioritization, and quantitative analysis remain limited. Here, we establis...
In this work, a three-dimensional (3D) tubular composite electrode was fabricated for the high-sensitivity electrochemical detection of ascorbic acid (AA). The differential pulse voltammetry (DPV) was employed to investigate the electrochemical behav...
Blue-emitting CdSe/ZnS quantum dots require precise control of crystal growth because variations in particle size and surface structure can strongly influence their emission properties. In this study, blue-optical CdSe/ZnS core–shell quantum do...
Green nanomaterials have attracted considerable attention for environmental monitoring due to their sustainability and multifunctional properties. In this study, copper oxide nanoparticles were synthesized using pomegranate peel (pp) extract (CuO@PP)...
Fourier-transform infrared (FT-IR) spectroscopy provides rapid, accessible, and chemically informative molecular fingerprints, but quantitative analysis of complex samples is often hindered by band overlap, baseline variation, matrix effects, and non...
Chloride quantification is crucial for environmental monitoring, marine research, and the durability assessment of geotechnical infrastructures, yet accurate measurement in complex aqueous and soil matrices remains challenging. Optical fiber sensors...
To address the dual challenges of environmental temperature–humidity fluctuations and spurious impulse artifacts in real-time IoT monitoring, this paper proposes a novel digital sensor signal denoising method based on wavelet packet decompositi...
Food fraud and adulteration continue to threaten food safety, consumer confidence and international trade. The challenges of investigating food-forensics reliably are compounded by increasingly complex supply chains, changing deceptive practices and...
Reduced nicotinamide adenine dinucleotide phosphate (NADPH) sustains reductive biosynthesis, antioxidant defense, oxidase activity, and redox signaling; nevertheless, studies framed as “NADPH imaging” often interrogate biochemically non-e...
X-ray fluorescence (XRF) chlorine analyzers are widely used for chlorine determination in crude oil and petroleum products. Although analytical test procedures are standardized, a calibration-oriented uncertainty framework for the analyzer itself rem...
Chiral covalent organic frameworks (CCOFs) merge the structural versatility of covalent organic frameworks with chirality, offering a powerful platform for enantioselective electrochemical sensing. This review comprehensively summarizes recent advanc...
Traditional tin dioxide (SnO2) gas sensors suffer from high operating temperatures and poor sensing response toward ammonia (NH3) at room temperature. Herein, flower-like CeO2/SnO2 n-n heterostructures are fabricated via a facile one-pot solvothermal...
Chronic kidney disease (CKD) is associated with metabolic alterations that may affect the volatile organic compound (VOC) profiles of biological fluids. Electronic nose systems capture complex VOC patterns as characteristic sensor-response fingerprin...
A calix[4]arene-based fluorescent chemosensor containing two quinolinium units (C4-BisQ) was synthesized and evaluated for the selective detection of cyanide (CN−). C4-BisQ showed a dual-mode optical response with a green-to-blue color change u...
The increasing use of germanium in advanced technologies and its potential release into aquatic environments demand sensitive and accessible analytical methods for its determination at trace levels. This work reports the development of an adsorptive...
A red-emissive, derivatization-assisted aptasensor was developed for acrylamide analysis in food. Acrylamide was first converted into the xanthydrol–acrylamide adduct (XAA), which was recognized by the DNA aptamer AptXAA. A π-conjugation-ext...
Background: The characterisations of highly diluted preparations impregnated onto solid carriers remains analytically challenging, particularly when residual material is present at very low levels. Electrophotonic analysis (EPA), based on corona-disc...
To address the quantitative distortion problem caused by the primary internal filtration effect (PIFE) resulting from coexisting substances in the fluorescence detection of aromatic pollutants, this study proposes a multi-component concentration quan...
In this study, an electrochemical sensor based on a graphitized carboxylated multi-walled carbon nanotube/polyaniline (G-COOH-MWCNTs/PANI) composite was developed for the highly sensitive detection of Pb2+ in seawater. A G-COOH-MWCNTs/PANI composite...
MicroRNAs (miRNAs) represent highly promising biomarkers for non-invasive clinical diagnostics. To overcome the limitations of conventional methods, Field-Effect Transistor biosensors (bioFETs) emerge as compelling alternatives by providing label-fre...
Micro- and nanoplastics have emerged as persistent, mobile water contaminants capable of carrying co-pollutants such as phthalates, polycyclic aromatic hydrocarbons and antibiotic-resistant pathogens, yet detection methods for this size range remain...
