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Genes, Volume 10, Issue 7

July 2019 - 74 articles

Cover Story: The human gut microbiota, that means the types of organisms that are present in an environmental habitat, consisting of trillions of microbial cells and thousands of bacterial species and it encompasses ~10−13 microorganisms. A growing body of evidence suggests that gut microbial communities play a fundamental role in many aspects of human health and diseases and, in turn, they are influenced by environment and nutritional behaviors. One of the most popular diets is the very low carbohydrate aka ketogenic diet. (KD). The KD is used for different aims: from weight loss to neurological diseases but its impact on microbiota is still poorly investigated but we know that ketones (produced during a KD) have positive effects on gut’s health. We investigated the complex interactions between ketogenic diet and gut microbiota and how this large network may influence human health. View this paper.
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Articles (74)

  • Article
  • Open Access
23 Citations
5,582 Views
11 Pages

Identification and Expression of SAUR Genes in the CAM Plant Agave

  • Gang Deng,
  • Xing Huang,
  • Li Xie,
  • Shibei Tan,
  • Thomas Gbokie,
  • Yaning Bao,
  • Zhouli Xie and
  • Kexian Yi

23 July 2019

Agave species are important crassulacean acid metabolism (CAM) plants and widely cultivated in tropical areas for producing tequila spirit and fiber. The hybrid H11648 of Agave ((A. amaniensis × A. angustifolia) × A. amaniensis) is the ma...

  • Article
  • Open Access
29 Citations
10,129 Views
27 Pages

Chromatin Interaction Analysis with Updated ChIA-PET Tool (V3)

  • Guoliang Li,
  • Tongkai Sun,
  • Huidan Chang,
  • Liuyang Cai,
  • Ping Hong and
  • Qiangwei Zhou

22 July 2019

Understanding chromatin interactions is important because they create chromosome conformation and link the cis- and trans- regulatory elements to their target genes for transcriptional regulation. Chromatin Interaction Analysis with Paired-End Tag (C...

  • Review
  • Open Access
141 Citations
23,520 Views
19 Pages

A Guide on Deep Learning for Complex Trait Genomic Prediction

  • Miguel Pérez-Enciso and
  • Laura M. Zingaretti

20 July 2019

Deep learning (DL) has emerged as a powerful tool to make accurate predictions from complex data such as image, text, or video. However, its ability to predict phenotypic values from molecular data is less well studied. Here, we describe the theoreti...

  • Article
  • Open Access
13 Citations
4,238 Views
7 Pages

Venous Thromboembolism in Prader–Willi Syndrome: A Questionnaire Survey

  • Ann M. Manzardo,
  • Janalee Heinemann,
  • Barbara McManus,
  • Carolyn Loker,
  • James Loker and
  • Merlin G. Butler

19 July 2019

Prader–Willi Syndrome Association (USA) monitors the ongoing health and welfare of individuals with Prader–Willi syndrome (PWS) through active communication with members by membership surveys and data registries. Thromboembolism and blood...

  • Concept Paper
  • Open Access
15 Citations
6,535 Views
20 Pages

When Three Isn’t a Crowd: A Digyny Concept for Treatment-Resistant, Near-Triploid Human Cancers

  • Kristine Salmina,
  • Bogdan I. Gerashchenko,
  • Michael Hausmann,
  • Ninel M. Vainshelbaum,
  • Pawel Zayakin,
  • Juris Erenpreiss,
  • Talivaldis Freivalds,
  • Mark S. Cragg and
  • Jekaterina Erenpreisa

19 July 2019

Near-triploid human tumors are frequently resistant to radio/chemotherapy through mechanisms that are unclear. We recently reported a tight association of male tumor triploidy with XXY karyotypes based on a meta-analysis of 15 tumor cohorts extracted...

  • Article
  • Open Access
15 Citations
4,955 Views
19 Pages

Transcriptome Analysis of Landrace Pig Subcutaneous Preadipocytes during Adipogenic Differentiation

  • Xitong Zhao,
  • Shaokang Chen,
  • Zhen Tan,
  • Yuan Wang,
  • Fengxia Zhang,
  • Ting Yang,
  • Yibing Liu,
  • Hong Ao,
  • Kai Xing and
  • Chuduan Wang

19 July 2019

Fat deposition in pigs, which significantly contributes to meat quality, fattening efficiency, reproductive performance, and immunity, is critically affected by preadipocyte adipogenic differentiation. We elucidated adipogenesis in pigs using transcr...

  • Article
  • Open Access
8 Citations
4,664 Views
14 Pages

18 July 2019

Genome-wide association studies have identified over 150 risk loci that increase prostate cancer risk. However, few causal variants and their regulatory mechanisms have been characterized. In this study, we utilized our previously developed single-nu...

  • Review
  • Open Access
7 Citations
7,287 Views
15 Pages

Computational Processing and Quality Control of Hi-C, Capture Hi-C and Capture-C Data

  • Peter Hansen,
  • Michael Gargano,
  • Jochen Hecht,
  • Jonas Ibn-Salem,
  • Guy Karlebach,
  • Johannes T. Roehr and
  • Peter N. Robinson

18 July 2019

Hi-C, capture Hi-C (CHC) and Capture-C have contributed greatly to our present understanding of the three-dimensional organization of genomes in the context of transcriptional regulation by characterizing the roles of topological associated domains,...

  • Article
  • Open Access
9 Citations
4,464 Views
17 Pages

Characterization of Solanum melongena Thioesterases Related to Tomato Methylketone Synthase 2

  • Vy Le Uyen Khuat,
  • Vi Thi Tuong Bui,
  • Huong Thi Diem Tran,
  • Nuong Xuan Truong,
  • Thien Chi Nguyen,
  • Phuc Huynh Hanh Mai,
  • Tuan Le Anh Dang,
  • Hiep Minh Dinh,
  • Hong Thi Anh Pham and
  • Thuong Thi Hong Nguyen

18 July 2019

2-Methylketones are involved in plant defense and fragrance and have industrial applications as flavor additives and for biofuel production. We isolated three genes from the crop plant Solanum melongena (eggplant) and investigated these as candidates...

  • Article
  • Open Access
25 Citations
5,910 Views
18 Pages

Transcriptome Analysis of Differentially Expressed Genes Related to the Growth and Development of the Jinghai Yellow Chicken

  • Fuxiang Chen,
  • Pengfei Wu,
  • Manman Shen,
  • Mingliang He,
  • Lan Chen,
  • Cong Qiu,
  • Huiqiang Shi,
  • Tao Zhang,
  • Jiahong Wang and
  • Kaizhou Xie
  • + 3 authors

17 July 2019

The growth traits are important traits in chickens. Compared to white feather broiler breeds, Chinese local broiler breeds have a slow growth rate. The main genes affecting the growth traits of local chickens in China are still unclear and need to be...

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Genes - ISSN 2073-4425