Curr. Oncol., Volume 28, Issue 2 (April 2021) – 48 articles
Cover Story (view full-size image): This overview of all randomized controlled trials (RCTs) published globally shows that Canada plays a meaningful role in the international cancer research community. Canadian RCTs are heavily dependent on funding from the pharmaceutical industry and primarily test new systemic therapies in the palliative context. Only one third of positive Canadian trials (and 13% of all trials) identify a new treatment that is associated with substantial clinical benefit; therefore, urgent efforts to improve on this are warranted. It is notable that only 14% of Canadian trials are conducted without industry funding. These data highlight the need for more investment in cancer clinical trials from the government and philanthropic sectors to ensure that Canadian RCTs address diseases and questions that are most likely to improve outcomes for patients in Canada and beyond. View this paper
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