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10,982 Results Found

  • Article
  • Open Access
45 Citations
3,913 Views
11 Pages

Rural domestic sewage treatment is not only an important part of the renovation of rural human settlements, but also a major measure to revitalize those areas. In the absence of extensive participation by farmers, it is difficult to achieve desired r...

  • Article
  • Open Access
1 Citations
978 Views
12 Pages

12 February 2015

We clarify patient participation by developing a systematic structure of 34=81 models spanned out by three subcategories for each of four categories. Choosing a qualitative descriptive research design, and applying purposive sampling, four doctors, s...

  • Article
  • Open Access
3 Citations
3,906 Views
13 Pages

Community Participation in and Perception of Community-Directed Treatment with Ivermectin in Kinshasa, DRC

  • Jean-Claude Makenga Bof,
  • Paul Mansiangi,
  • Horlyne Nsangi,
  • Éric Mafuta,
  • Isabelle Aujoulat and
  • Yves Coppieters

The success of community-directed treatment with Ivermectin (CDTI) depends on active community participation. We conducted a case study nested in a cross-sectional study in the Binza Ozone Health Zone (ZS) in Kinshasa, Democratic Republic of Congo, i...

  • Article
  • Open Access
5 Citations
3,789 Views
12 Pages

10 March 2022

Background: Community-dwelling adults who can perform self-care behaviors related to making treatment decisions and participating in treatment have been found to use less emergency care. In this exploratory study, we examined the relationships in old...

  • Article
  • Open Access
18 Citations
4,370 Views
17 Pages

23 March 2021

During China’s rapid economic development and urbanization, numerous cases of urban malodorous black river (MBR) have occurred. MBR refers to a polluted urban river that smells bad, is almost black in color, has no aquatic plants or animals, and that...

  • Review
  • Open Access
17 Citations
5,365 Views
50 Pages

Participation of MicroRNAs in the Treatment of Cancer with Phytochemicals

  • Seung Wan Son,
  • Han Yeoung Lee,
  • Sokviseth Moeng,
  • Hyo Jeong Kuh,
  • Soo Young Choi and
  • Jong Kook Park

14 October 2020

Cancer is a global health concern and one of the main causes of disease-related death. Even with considerable progress in investigations on cancer therapy, effective anti-cancer agents and regimens have thus far been insufficient. There has been comp...

  • Article
  • Open Access
1,404 Views
12 Pages

Improving the Effectiveness of Conservative Treatment of Idiopathic Scoliosis Through Active Parental Participation During Inpatient Rehabilitation

  • Marianna Białek,
  • Justyna Pękala,
  • Ewelina Białek-Kucharska,
  • Małgorzata Poczynek,
  • Paulina Poświata and
  • Tomasz Kotwicki

Background/Objectives: This is a study of adolescents with idiopathic scoliosis (IS), treated by the Functional Individual Therapy of Scoliosis (FITS) method. The hypothesis was that active parental involvement in the treatment process enhances the o...

  • Article
  • Open Access
48 Citations
1,499 Views
9 Pages

1 August 2010

Introduction: A growing number of psychosocial interventions are being offered to cancer patients during and after their medical treatment. Here, we examined whether Mindfulness-Based Stress Reduction (MBSR), a stress management course, helps women t...

  • Article
  • Open Access
3 Citations
2,734 Views
14 Pages

The efficacy of internet and mobile-based interventions (IMIs) has been demonstrated with different mental health disorders, but little is known about the mediating effect of phobic anxiety on activity and participation and the differential effect of...

  • Article
  • Open Access
654 Views
14 Pages

Integrative Analysis of Omics Reveals RdDM Pathway Participation in the Initiation of Rice Microspore Embryogenesis Under Cold Treatment

  • Yingbo Li,
  • Runhong Gao,
  • Yingjie Zong,
  • Guimei Guo,
  • Wenqi Zhang,
  • Zhiwei Chen,
  • Jiao Guo and
  • Chenghong Liu

23 July 2025

Abiotic stress can reprogram the gametophytic pathway; the mechanisms by which floral bud pre-treatment influences microspore embryogenesis initiation remain unclear. In this study, we use bisulfite sequencing, sRNA-seq, and RNA-seq to analyze the dy...

  • Article
  • Open Access
7 Citations
10,714 Views
18 Pages

17 November 2019

Irrigation remains a critical input into farming and, therefore, it remains a proxy for food security and poverty alleviation in developing countries. Despite their role in economic growth and the received investment, irrigation schemes are still und...

  • Review
  • Open Access
2 Citations
5,834 Views
21 Pages

Psychodynamic Therapies for the Treatment of Substance Addictions: A PRISMA Meta-Analysis

  • Marco Zuccon,
  • Eleonora Topino,
  • Alessandro Musetti and
  • Alessio Gori

7 October 2023

The aim of this meta-analysis was to compare psychodynamic with other treatments in studies of substance addiction. The literature search was conducted using the PubMed, Web of Science, Cohcrane library, SCOPUS, and Onesearch databases. All studies c...

  • Article
  • Open Access
5 Citations
4,145 Views
23 Pages

Communities’ Perception, Knowledge, and Practices Related to Human African Trypanosomiasis in the Democratic Republic of Congo

  • Charlie Kabanga,
  • Olaf Valverde Mordt,
  • Florent Mbo,
  • Medard Mbondo,
  • Donatien Olela,
  • Rinelle Etinkum,
  • Dieudonne Nkaji,
  • Bienvenu Mukoso and
  • Lubanza Mananasi

26 September 2022

Background: The number of human African trypanosomiasis (HAT) cases in the Democratic Republic of Congo (DRC) has significantly reduced, thanks to more effective drugs and screening tools and regular mass screening. However, this potentially jeopardi...

  • Article
  • Open Access
5 Citations
3,486 Views
11 Pages

The opioid epidemic is a public health crisis that disproportionately affects our unsheltered neighbors. Because medication-assisted treatment (MAT) is effective for preventing deaths from drug overdose and retention is associated with better health...

  • Article
  • Open Access
11 Citations
3,594 Views
24 Pages

As our cities grow, it is important to develop policies and streetscape designs that provide pedestrians with safe comfortable walking conditions and acknowledge the challenges involved in making urban places feel liveable and safe while understandin...

  • Article
  • Open Access
1 Citations
4,143 Views
22 Pages

Wastewater Management Strategies in Rural Communities Using Constructed Wetlands: The Role of Community Participation

  • Brenda Lizeth Monzón-Reyes,
  • Humberto Raymundo González-Moreno,
  • Alex Elías Álvarez Month,
  • Alexi Jose Peralta Vega,
  • Gaston Ballut-Dajud and
  • Luis Carlos Sandoval Herazo

27 March 2025

The lack of access to centralized technologies and economic resources in rural communities makes wastewater management a critical challenge. Decentralized systems such as constructed wetlands offer sustainable solutions by leveraging natural processe...

  • Article
  • Open Access
24 Citations
7,849 Views
27 Pages

Affordability of Decentralized Wastewater Systems: A Case Study in Integrated Planning from INDIA

  • Norbert Brunner,
  • Markus Starkl,
  • Absar A. Kazmi,
  • Alvaro Real,
  • Nitin Jain and
  • Vijay Mishra

13 November 2018

Based on experiences about the planning of decentralized wastewater treatment systems for slums of two rural towns in India, the paper asks to what extent affordability for the future users may impede the realization of other sustainability goals. Th...

  • Article
  • Open Access
1 Citations
1,542 Views
25 Pages

Chronic Pain Prevalence and Psychosocial Burden in the Italian Population from the 2019 European Health Interview Survey

  • Alice Maraschini,
  • Michael Tenti,
  • William Raffaeli,
  • Laura Iannucci,
  • Lidia Gargiulo,
  • Alessandra Burgio,
  • Giada Minelli,
  • Corrado Fagnani,
  • Emanuela Medda and
  • Maurizio Ferri
  • + 2 authors

Chronic pain (CP) is a global healthcare concern requiring careful monitoring. In Italy, the most recent CP prevalence estimates date back to 2003. In this work, we analyzed data from the 2019 European Health Interview Survey, based on a representati...

  • Communication
  • Open Access
2 Citations
2,445 Views
9 Pages

Probing Gut Participation in Parkinson’s Disease Pathology and Treatment via Stem Cell Therapy

  • Jea-Young Lee,
  • Vanessa Castelli,
  • Paul R. Sanberg and
  • Cesar V. Borlongan

Accumulating evidence suggests the critical role of the gut–brain axis (GBA) in Parkinson’s disease (PD) pathology and treatment. Recently, stem cell transplantation in transgenic PD mice further implicated the GBA’s contribution to...

  • Article
  • Open Access
5 Citations
4,592 Views
11 Pages

Effects of SLCO1B1 Genetic Variant on Metabolite Profile in Participants on Simvastatin Treatment

  • Lilian Fernandes Silva,
  • Rowmika Ravi,
  • Jagadish Vangipurapu,
  • Anniina Oravilahti and
  • Markku Laakso

22 November 2022

Organic-anion-transporting polypeptide 1B1 (OATP1B1), encoded by the solute carrier organic anion transporter family member 1B1 gene (SLCO1B1), is highly expressed in the liver and transports several endogenous metabolites into the liver, including s...

  • Article
  • Open Access
1,849 Views
10 Pages

Background: Understanding patient perceptions of cancer care is crucial for improving treatment experiences and health outcomes. This study explores female patient-reported experiences with cancer care. Our aim was to identify areas for improvement a...

  • Article
  • Open Access
9 Citations
7,397 Views
14 Pages

Around half of methadone maintenance treatment (MMT) participants choose the tapering phase, however, the guidelines on tapering differ between countries and only include the tapering rate. Physicians need more evidence to guide clinical practice. We...

  • Article
  • Open Access
11 Citations
4,107 Views
18 Pages

Harmonization and Visualization of Data from a Transnational Multi-Sensor Personal Exposure Campaign

  • Rok Novak,
  • Ioannis Petridis,
  • David Kocman,
  • Johanna Amalia Robinson,
  • Tjaša Kanduč,
  • Dimitris Chapizanis,
  • Spyros Karakitsios,
  • Benjamin Flückiger,
  • Danielle Vienneau and
  • Ondřej Mikeš
  • + 11 authors

Use of a multi-sensor approach can provide citizens with holistic insights into the air quality of their immediate surroundings and their personal exposure to urban stressors. Our work, as part of the ICARUS H2020 project, which included over 600 par...

  • Article
  • Open Access
9 Citations
4,268 Views
13 Pages

A Qualitative Study on Concerns, Needs, and Expectations of Hospital Patients Related to Climate Change: Arguments for a Patient-Centered Adaptation

  • Benedikt Lenzer,
  • Christina Hoffmann,
  • Peter Hoffmann,
  • Ursula Müller-Werdan,
  • Manuel Rupprecht,
  • Christian Witt,
  • Cornelius Herzig and
  • Uta Liebers

This study explores the concerns, needs, and expectations of inpatients with the goal to develop a patient-centered climate change adaptation agenda for hospitals. Statements of patients from geriatrics, internal medicine, psychiatry, and surgery (N...

  • Article
  • Open Access
12 Citations
11,718 Views
16 Pages

30 October 2014

A serious illness, a chronic medical condition or a hospital bed should not deny any child her/his basic right to play, a right essential for children’s development and general wellbeing. In fact, it is in these frightening and anxious moments that p...

  • Article
  • Open Access
10 Citations
4,516 Views
18 Pages

Exploring Public Perceptions and Disposal Procedures in the Development of a Comprehensive End-of-Life Vehicle Regulation in Malaysia: A Pilot Study

  • Hasani Mohd Ali,
  • Vladimir Simic,
  • Charli Sitinjak,
  • Jady Zaidi Hassim,
  • Muhamad Helmi Md Said,
  • Rasyikah Md Khalid,
  • Grace Emmanuel Kaka and
  • Rozmi Ismail

8 March 2023

The growing global demand for new cars has resulted in a rise in end-of-life vehicles (ELV), both with usable and non-usable parts. Malaysia faces a particularly pressing issue of abandoned vehicles (AVs), as the country currently lacks comprehensive...

  • Article
  • Open Access
1,509 Views
18 Pages

A Longitudinal Transdisciplinary Approach for Autism Spectrum Disorder

  • Aline Kabarite,
  • Glória Maria Marques Ferreira,
  • José Carlos Pitangueira,
  • Rayana de Souza Arimatéa,
  • Renata da Costa Rebello de Mendonça,
  • Roberta Sousa Marcello,
  • Thais Giudice Schulz,
  • Rudimar dos Santos Riesgo and
  • Kamila Castro

22 September 2025

Background/Objectives: Autism Spectrum Disorder (ASD) presents complex developmental challenges that require coordinated, individualized interventions. This study aimed to evaluate the effectiveness of a transdisciplinary, family-centered approach in...

  • Systematic Review
  • Open Access
43 Citations
7,001 Views
13 Pages

The Contribution of “Individual Participant Data” Meta-Analyses of Psychotherapies for Depression to the Development of Personalized Treatments: A Systematic Review

  • Pim Cuijpers,
  • Marketa Ciharova,
  • Soledad Quero,
  • Clara Miguel,
  • Ellen Driessen,
  • Mathias Harrer,
  • Marianna Purgato,
  • David Ebert and
  • Eirini Karyotaki

11 January 2022

While randomized trials typically lack sufficient statistical power to identify predictors and moderators of outcome, ”individual participant data” (IPD) meta-analyses, which combine primary data of multiple randomized trials, can increas...

  • Article
  • Open Access
9 Citations
3,435 Views
12 Pages

Modification of Body-Related Attentional Bias through Virtual Reality and Eye-Tracking in Healthy Participants: Implications for Anorexia Nervosa Treatments

  • Helena Miquel-Nabau,
  • Natalia Briseño-Oloriz,
  • Bruno Porras-Garcia,
  • Mariarca Ascione,
  • Franck-Alexandre Meschberger-Annweiler,
  • Marta Ferrer-Garcia,
  • Manuel Moreno-Sanchez,
  • Eduardo Serrano-Troncoso,
  • Marta Carulla-Roig and
  • José Gutiérrez Maldonado

Cognitive biases have a significant impact on the etiology and treatment of eating disorders (EDs). These biases, including selective attentional bias (AB) to disliked body parts, may reinforce concerns about body shape, fear of gaining weight and bo...

  • Article
  • Open Access
3 Citations
3,031 Views
14 Pages

Results of a Randomized, Double-Blind, Placebo-Controlled, Phase 1b/2 Trial of Nabpaclitaxel + Gemcitabine ± Olaratumab in Treatment-Naïve Participants with Metastatic Pancreatic Cancer

  • Faithlore P. Gardner,
  • Zev A. Wainberg,
  • Christos Fountzilas,
  • Nathan Bahary,
  • Mark S. Womack,
  • Teresa Macarulla,
  • Ignacio Garrido-Laguna,
  • Patrick M. Peterson,
  • Erkut Borazanci and
  • Melissa Johnson
  • + 2 authors

28 March 2024

The efficacy and safety of olaratumab plus nabpaclitaxel and gemcitabine in treatment-naïve participants with metastatic pancreatic ductal adenocarcinoma was evaluated. An initial phase 1b dose-escalation trial was conducted to determine the ola...

  • Article
  • Open Access
450 Views
13 Pages

Long-Term Study of the Changes in Symptoms and Signs of Dry Eye Disease in Participants Non-Adherent to Treatment

  • Belen Sabucedo-Villamarin,
  • Jacobo Garcia-Queiruga,
  • Hugo Pena-Verdeal,
  • María José Ginzo-Villamayor,
  • Carlos Garcia-Resua,
  • Maria J. Giraldez and
  • Eva Yebra-Pimentel

20 November 2025

Background: The purpose of this study was to assess differences in clinical symptoms and signs of DED in non-adherent to treatment patients to describe long-term disease progression. Methods: 120 patients previously diagnosed with Dry Eye Disease (DE...

  • Article
  • Open Access
28 Citations
4,499 Views
12 Pages

While effective for slowing the transmission of SARS-CoV-2, public health measures, such as physical distancing and stay-at-home orders, have significantly shifted the way people interact and maintain social connections. To better understand how peop...

  • Article
  • Open Access
6 Citations
2,915 Views
13 Pages

The quality of family relationships is important for individual and family well-being. Improving family relationships is also an important goal in methadone maintenance treatment (MMT). Little is known about factors associated with the improvement of...

  • Article
  • Open Access
6 Citations
2,740 Views
14 Pages

22 November 2020

Recurrent pain is a common experience in childhood and adolescence and can result in significant disability in youth, including poor quality of life, school absences, and reduced social activities. Evidence has linked adolescent risk and resilience f...

  • Systematic Review
  • Open Access
7 Citations
3,499 Views
13 Pages

3 July 2023

Diffuse midline glioma (DMG), H3 K27-altered are highly aggressive, incurable central nervous system (CNS) tumors. The current standard palliative treatment is radiotherapy, with most children succumbing to the disease in less than one year from...

  • Article
  • Open Access
14 Citations
8,929 Views
18 Pages

15 December 2017

Chronic pain can lead to significant negative outcomes across many areas of life. Recently, mindfulness-based interventions (MBIs) have been identified as potentially effective tools for improved pain management among adolescents living with pain. Th...

  • Article
  • Open Access
17 Citations
5,627 Views
15 Pages

The gender identity of trans individuals influences their treatment preferences, and this in turn seems to affect their individual treatment progress. However, there has been no research which—next to the impact of gender identity on treatment...

  • Brief Report
  • Open Access
1 Citations
2,909 Views
7 Pages

11 September 2024

Research conducted on homogenous populations can lead to biased and misleading findings, impeding the development of effective interventions and treatments for diverse populations. Low participation among minority groups further leads to disparities...

  • Article
  • Open Access
1 Citations
3,529 Views
15 Pages

A Comparison of the Efficacy of Online HAPIFED versus Online Cognitive Behavioural Therapy for Binge Eating Disorder: A Randomized Controlled Trial

  • Felipe Q. da Luz,
  • Mohammed Mohsin,
  • Paula C. Teixeira,
  • Edilaine dos Santos,
  • Tamiris Gaeta,
  • Silvia Ferrari,
  • Kayo Martin,
  • Andréia Dias,
  • Tatiana A. Jana and
  • Leticia S. Marinho
  • + 4 authors

13 June 2024

The efficacy of two different online treatment programs for people with binge eating disorder (BED) was compared. One hundred and nineteen adults with BED were randomized to treatments based on the Healthy Approach to Weight Management and Food in Ea...

  • Article
  • Open Access
705 Views
15 Pages

High Levels of Community Support for Mansonellosis Interventions in an Endemic Area of the Brazilian Amazon

  • Uziel Ferreira Suwa,
  • Carla Letícia Gomes Simão,
  • Ulysses Carvalho Barbosa,
  • Patrícia Moura Sousa,
  • Cláudia Patrícia Mendes de Araújo,
  • Marilaine Martins and
  • James Lee Crainey

Mansonellosis is a chronic infectious tropical disease that affects hundreds of millions of people worldwide but is not currently targeted for control. In this study, we interviewed 320 residents from Sao Gabriel do Cachoeira (SGC) about their suppor...

  • Article
  • Open Access
9 Citations
2,898 Views
12 Pages

3 February 2021

Meniscal tear is a common reason for patients to undergo knee operation, and the medial meniscus posterior root tear (MMPRT) is one of the most frequent kinds of meniscal tears. The purpose of this study was to analyze participants’ factors (anthropo...

  • Article
  • Open Access
15 Citations
1,034 Views
6 Pages

1 October 2017

Background: Radiotherapy (RT) has been the standard treatment for early oropharyngeal cancer, achieving excellent outcomes, but with significant toxicities. Transoral robotic surgery (TORS) has emerged as a promising alternative. A decision aid (DA)...

  • Article
  • Open Access
4 Citations
2,246 Views
12 Pages

This study explores patients’ opportunities for collective participation in an institution for people with substance use disorder. Patients and staff from the treatment institution cooperated with researchers to make changes in the treatment practice...

  • Article
  • Open Access
3 Citations
4,450 Views
12 Pages

Treatment adherence in adults with cystic fibrosis (CF) is poor. One of the reasons identified for lack of adherence to nebulised treatments is that patients may not experience any immediate relief in their symptoms or notice changes as a result of t...

  • Article
  • Open Access
889 Views
16 Pages

12 July 2025

Using the behavioral model of engagement in health services, the current study assessed client characteristics that may contribute to treatment duration in trauma-focused psychotherapy in a community clinic setting. Participants (n = 893) were adults...

  • Article
  • Open Access
2 Citations
3,053 Views
11 Pages

Studies suggest that intensive oral health promotion programs in the workplace reduce dental and medical care expenditures. The purpose of this longitudinal study was to evaluate the short version of an oral health promotion program in the workplace...

  • Article
  • Open Access
1 Citations
3,441 Views
17 Pages

Isotretinoin Concerns in Switzerland: A Student-Based Transversal Study

  • Anna-Lena U. Jakobi,
  • Andreas J. Bircher,
  • Alberto Pagnamenta and
  • Isabella Terrani

7 March 2025

Background/Objectives: Concerns about isotretinoin may affect both initiation and adherence in acne patients. We conducted a student-based transversal study including participants with knowledge on isotretinoin to assess related concerns and factors...

  • Article
  • Open Access
6 Citations
4,511 Views
14 Pages

The Influence of Orthodontic Treatment Need on Oral Health-Related Quality of Life among 12–18-Year-Old Adolescents in Riyadh

  • Nancy Ajwa,
  • Arwa AlHammad,
  • Luluh AlAmmar,
  • Munira AlMarjan,
  • Talal AlShugair,
  • Leen AlManie and
  • Durgesh Bangalore

28 October 2022

This study assessed the prevalence of orthodontic treatment needs and oral health-related quality of life (OHRQoL) in 12–18-year-old adolescents and explored the association between OHRQoL and treatment needs, gender, education level and family...

  • Article
  • Open Access
1,833 Views
12 Pages

Lumbar Tractions in Radicular Pain Caused by Herniated Disc: Randomised, Open-Label, Superiority, and Controlled Trial on 424 Participants

  • Elsa Bernhard,
  • Ambre Hittinger-Roux,
  • Helene Delaplace,
  • Loïc Pauvele,
  • Isabelle Charlot,
  • Marion Geoffroy,
  • Lukshe Kanagaratnam,
  • Christophe Eap,
  • Christophe Mensa and
  • Loïs Bolko
  • + 1 author

22 July 2025

Background/Objectives: Radicular pain is a frequent pathology, and disc herniation is the commonest aetiology. A meta-analysis summarising international guidelines for radicular pain, published in 2021, showed that lumbar traction’s place is st...

  • Article
  • Open Access
10 Citations
3,120 Views
12 Pages

Background: The aim of this study was to investigate the effect of lower urinary tract symptoms (LUTS) on behavior related to treatment of Polish adults aged ≥ 40 years. Methods: We conducted a computer-assisted telephone survey with a study sampl...

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