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65 Results Found

  • Article
  • Open Access
5 Citations
2,907 Views
13 Pages

16 December 2022

Alternative splicing (AS) is a regulatory mechanism of post-transcriptional regulation that plays an important role in plant response to abiotic stresses. However, corresponding research involving the mechanism of AS in the nitrogen starvation respon...

  • Article
  • Open Access
7 Citations
4,991 Views
21 Pages

Comparative Analysis Based on Transcriptomics and Metabolomics Data Reveal Differences between Emmer and Durum Wheat in Response to Nitrogen Starvation

  • Romina Beleggia,
  • Nooshin Omranian,
  • Yan Holtz,
  • Tania Gioia,
  • Fabio Fiorani,
  • Franca M. Nigro,
  • Nicola Pecchioni,
  • Pasquale De Vita,
  • Ulrich Schurr and
  • Roberto Papa
  • + 2 authors

Mounting evidence indicates the key role of nitrogen (N) on diverse processes in plant, including development and defense. Using a combined transcriptomics and metabolomics approach, we studied the response of seedlings to N starvation of two differe...

  • Article
  • Open Access
35 Citations
9,089 Views
17 Pages

13 March 2015

Nitrogen starvation acclimation in non-diazotrophic cyanobacteria is characterized by a process termed chlorosis, where the light harvesting pigments are degraded and the cells gradually tune down photosynthetic and metabolic activities. The chlorosi...

  • Article
  • Open Access
13 Citations
5,591 Views
38 Pages

β-N-Methylamino-L-Alanine (BMAA) Causes Severe Stress in Nostoc sp. PCC 7120 Cells under Diazotrophic Conditions: A Proteomic Study

  • Olga A. Koksharova,
  • Ivan O. Butenko,
  • Olga V. Pobeguts,
  • Nina A. Safronova and
  • Vadim M. Govorun

30 April 2021

Non-proteinogenic neurotoxic amino acid β-N-methylamino-L-alanine (BMAA) is synthesized by cyanobacteria, diatoms, and dinoflagellates, and is known to be a causative agent of human neurodegenerative diseases. Different phytoplankton organisms’ abili...

  • Article
  • Open Access
5 Citations
3,433 Views
11 Pages

Changes in the Root Architecture of Oil Palm Seedlings in Response to Nitrogen Starvation

  • Marlon De la Peña,
  • Rodrigo Ruiz-Romero,
  • Laura Isabel Castro-Arza and
  • Hernán Mauricio Romero

20 February 2024

Oil palm (Elaeis guineensis) is a widely cultivated crop known for its high oil yield. It is cultivated extensively across tropical regions, notably in Southeast Asia, Africa, and Latin America. It plays a vital role in global vegetable oil supply, m...

  • Feature Paper
  • Article
  • Open Access
13 Citations
3,298 Views
25 Pages

21 April 2021

Stress events have transgenerational effects on plant growth and development. In Mediterranean regions, water-deficit and heat (WH) stress is a frequent issue that negatively affects crop yield and quality. Nitrogen (N) is an essential plant macronut...

  • Communication
  • Open Access
14 Citations
3,708 Views
8 Pages

7 November 2020

Non-diazotrophic cyanobacteria are unable to fix atmospheric nitrogen and rely on combined nitrogen for growth and development. In the absence of combined nitrogen sources, most non-diazotrophic cyanobacteria, e.g., Synechocystis sp. PCC 6803 or Syne...

  • Article
  • Open Access
1 Citations
1,612 Views
15 Pages

13 February 2025

Nitrogen (N) is the most important fertilizer for increasing crop production, as it is absorbed by various N transporters and metabolized by a series of enzymes. Aspartate aminotransferase (ASP) facilitates the conversion of Glu to Asp for N storage....

  • Article
  • Open Access
2,088 Views
13 Pages

A Maize Mutant Impaired in SL Biosynthesis (zmccd8) Shows a Lower Growth, an Altered Response to Nitrogen Starvation, and a Potential Secondary Effect on Drought Tolerance

  • Laura Ravazzolo,
  • Andrea Chichi,
  • Franco Meggio,
  • Leonardo Buzzicotti,
  • Benedetto Ruperti,
  • Serena Varotto,
  • Mario Malagoli and
  • Silvia Quaggiotti

25 September 2024

Strigolactones (SLs) are essential phytohormones involved in plant development and interaction with the rhizosphere, regulating shoot branching, root architecture, and leaf senescence for nutrient reallocation. The Zea mays L. zmccd8 mutant, defectiv...

  • Article
  • Open Access
7 Citations
3,755 Views
23 Pages

The maintenance of adaptability to the exposure to agroecological extreme environments is generally a feature after the long-term domestication of crops. Auxin influences plant growth in all environments. At present, the research on the auxin respons...

  • Article
  • Open Access
20 Citations
3,169 Views
12 Pages

30 September 2022

Nitrogen deprivation is known to improve lipid accumulation in microalgae and thraustochytrids. However, the patterns of fatty acid production and the molecular mechanisms underlying the accumulation of unsaturated and saturated fatty acids (SFAs) un...

  • Article
  • Open Access
2 Citations
3,298 Views
10 Pages

14 September 2021

To understand the relationship between carbon or nitrogen utilization and iron homeostasis, we performed an iron uptake assay with several deletion mutants with partial defects in carbon or nitrogen metabolism. Among them, some deletion mutants defec...

  • Article
  • Open Access
11 Citations
2,504 Views
17 Pages

Enhanced Autophagic Activity Improved the Root Growth and Nitrogen Utilization Ability of Apple Plants under Nitrogen Starvation

  • Liuqing Huo,
  • Zijian Guo,
  • Qi Wang,
  • Li Cheng,
  • Xin Jia,
  • Ping Wang,
  • Xiaoqing Gong,
  • Cuiying Li and
  • Fengwang Ma

Autophagy is a conserved degradation pathway for recycling damaged organelles and aberrant proteins, and its important roles in plant adaptation to nutrient starvation have been generally reported. Previous studies found that overexpression of autoph...

  • Article
  • Open Access
39 Citations
5,002 Views
16 Pages

Alternative Polyadenylation and Salicylic Acid Modulate Root Responses to Low Nitrogen Availability

  • Carlos M. Conesa,
  • Angela Saez,
  • Sara Navarro-Neila,
  • Laura de Lorenzo,
  • Arthur G. Hunt,
  • Edgar B. Sepúlveda,
  • Roberto Baigorri,
  • Jose M. Garcia-Mina,
  • Angel M. Zamarreño and
  • Juan C. del Pozo
  • + 1 author

16 February 2020

Nitrogen (N) is probably the most important macronutrient and its scarcity limits plant growth, development and fitness. N starvation response has been largely studied by transcriptomic analyses, but little is known about the role of alternative poly...

  • Feature Paper
  • Article
  • Open Access
19 Citations
4,147 Views
18 Pages

20 April 2020

In eukaryotes, autophagy, a catabolic mechanism for macromolecule and protein recycling, allows the maintenance of amino acid pools and nutrient remobilization. For a better understanding of the relationship between autophagy and nitrogen metabolism,...

  • Article
  • Open Access
25 Citations
9,350 Views
15 Pages

30 June 2014

Nutrient balance is important for photosynthetic growth and biomass production in microalgae. Here, we investigated and compared metabolic responses of amino acid pools to nitrogen and sulfur starvation in a unicellular model cyanobacterium, Synecho...

  • Article
  • Open Access
6 Citations
4,561 Views
12 Pages

Nitrification upon Nitrogen Starvation and Recovery: Effect of Stress Period, Substrate Concentration and pH on Ammonia Oxidizers’ Performance

  • Leila Abbaszadeh,
  • Eleni Koutra,
  • Konstantina Tsigkou,
  • Maria Gaspari,
  • Panagiotis G. Kougias and
  • Michael Kornaros

Nitrification has been widely applied in wastewater treatment, however gaining more insight into the nitrifiers’ physiology and stress response is necessary for the optimization of nutrient removal and design of advanced processes. Since nitrif...

  • Article
  • Open Access
5 Citations
2,566 Views
15 Pages

Genome-Wide Identification of TaSAUR Gene Family Members in Hexaploid Wheat and Functional Characterization of TaSAUR66-5B in Improving Nitrogen Use Efficiency

  • Weizeng Lv,
  • Xue He,
  • Haojuan Guo,
  • Haibin Lan,
  • Yanqing Jiao,
  • Le Li,
  • Yanhao Lian,
  • Zhiqiang Wang,
  • Zeyu Xin and
  • Tongbao Lin
  • + 1 author

Excessive input of nitrogen fertilizer not only causes a great waste of resources but brings about a series of ecological and environmental problems. Although Small Auxin Up-regulated RNAs (SAURs) participate in diverse biological processes, the...

  • Article
  • Open Access
5 Citations
2,615 Views
23 Pages

29 December 2023

High-affinity nitrate transporters (NRT) are key components for nitrogen (N) acquisition and distribution within plants. However, insights on these transporters in wheat are scarce. This study presents a comprehensive analysis of the NRT2 and NRT3 ge...

  • Article
  • Open Access
7 Citations
2,934 Views
16 Pages

Microalgae-based biodiesel production has many advantages over crude oil extraction and refinement, thus attracting more and more concern. Protein ubiquitination is a crucial mechanism in eukaryotes to regulate physiological responses and cell develo...

  • Article
  • Open Access
11 Citations
1,751 Views
6 Pages

The unicellular red alga Galdieria sulphuraria is a polyextremophilic organism with a metabolic flexibility to grow autotrophically or heterotrophically. Galdieria can also produce and accumulate biotechnologically attractive products such as pigment...

  • Article
  • Open Access
13 Citations
4,476 Views
18 Pages

Genome-Wide Identification, Characterization, and Regulation of RWP-RK Gene Family in the Nitrogen-Fixing Clade

  • Zhihua Wu,
  • Hong Liu,
  • Wen Huang,
  • Lisha Yi,
  • Erdai Qin,
  • Tiange Yang,
  • Jing Wang and
  • Rui Qin

11 September 2020

RWP-RK is a plant-specific family of transcription factors, involved in nitrate response, gametogenesis, and nodulation. However, genome-wide characterization, phylogeny, and the regulation of RWP-RK genes in the nodulating and non-nodulating plant s...

  • Article
  • Open Access
22 Citations
4,323 Views
20 Pages

25 February 2020

Tea (Camellia sinensis (L.) O. Kuntze) is a widely consumed beverage. Lack of macronutrients is a major cause of tea yield and quality losses. Though the effects of macronutrient starvation on tea metabolism have been studied, little is known about t...

  • Article
  • Open Access
72 Citations
9,404 Views
22 Pages

Transcriptome Analysis of Two Rice Varieties Contrasting for Nitrogen Use Efficiency under Chronic N Starvation Reveals Differences in Chloroplast and Starch Metabolism-Related Genes

  • Subodh Kumar Sinha,
  • Amitha Mithra Sevanthi V.,
  • Saurabh Chaudhary,
  • Punit Tyagi,
  • Sureshkumar Venkadesan,
  • Manju Rani and
  • Pranab Kumar Mandal

11 April 2018

The nitrogen use efficiency (NUE) of crop plants is limited and enhancing it in rice, a major cereal crop, would be beneficial for farmers and the environment alike. Here we report the genome-wide transcriptome analysis of two rice genotypes, IR 64 (...

  • Review
  • Open Access
11 Citations
4,062 Views
8 Pages

6 October 2021

Target of rapamycin (TOR) kinases form two distinct complexes, TORC1 and TORC2, which are evolutionarily conserved among eukaryotes. These complexes control intracellular biochemical processes in response to changes in extracellular nutrient conditio...

  • Article
  • Open Access
31 Citations
11,290 Views
12 Pages

Metabolomic Analysis of Fission Yeast at the Onset of Nitrogen Starvation

  • Kenichi Sajiki,
  • Tomáš Pluskal,
  • Mizuki Shimanuki and
  • Mitsuhiro Yanagida

13 December 2013

Microorganisms naturally respond to changes in nutritional conditions by adjusting their morphology and physiology. The cellular response of the fission yeast S. pombe to nitrogen starvation has been extensively studied. Here, we report time course...

  • Article
  • Open Access
2 Citations
987 Views
14 Pages

1 August 2025

Background/Objectives: Nitrogen (N) is an essential macronutrient that strongly influences maize growth and metabolism. While many studies have focused on nitrogen responses during later developmental stages, early-stage physiological and metabolic r...

  • Article
  • Open Access
18 Citations
6,289 Views
27 Pages

The First Proteomic Study of Nostoc sp. PCC 7120 Exposed to Cyanotoxin BMAA under Nitrogen Starvation

  • Olga A. Koksharova,
  • Ivan O. Butenko,
  • Olga V. Pobeguts,
  • Nina A. Safronova and
  • Vadim M. Govorun

9 May 2020

The oldest prokaryotic photoautotrophic organisms, cyanobacteria, produce many different metabolites. Among them is the water-soluble neurotoxic non-protein amino acid beta-N-methylamino-L-alanine (BMAA), whose biological functions in cyanobacterial...

  • Article
  • Open Access
2 Citations
1,203 Views
24 Pages

The phosphate starvation response (PHR) transcription factor family play central regulatory roles in nutrient signaling, but its relationship with other abiotic stress remains elusive. In the woody plant Eucalyptus grandis, we characterized 12 EgPHRs...

  • Article
  • Open Access
3 Citations
2,446 Views
22 Pages

Proteomics of Paracoccidioides lutzii: Overview of Changes Triggered by Nitrogen Catabolite Repression

  • Vanessa Rafaela Milhomem Cruz-Leite,
  • André Luís Elias Moreira,
  • Lana O’Hara Souza Silva,
  • Moises Morais Inácio,
  • Juliana Alves Parente-Rocha,
  • Orville Hernandez Ruiz,
  • Simone Schneider Weber,
  • Célia Maria de Almeida Soares and
  • Clayton Luiz Borges

12 November 2023

Members of the Paracoccidioides complex are the causative agents of Paracoccidioidomycosis (PCM), a human systemic mycosis endemic in Latin America. Upon initial contact with the host, the pathogen needs to uptake micronutrients. Nitrogen is an essen...

  • Article
  • Open Access
8 Citations
4,804 Views
16 Pages

Hungry for Sex: Differential Roles for Ustilago maydisb Locus Components in Haploid Cells vis à vis Nutritional Availability

  • R. Margaret Wallen,
  • Kirsten Richardson,
  • Madison Furnish,
  • Hector Mendoza,
  • Allison Dentinger,
  • Sunita Khanal and
  • Michael H. Perlin

12 February 2021

Mating-types allow single-celled eukaryotic organisms to distinguish self from non-self in preparation for sexual reproduction. The components of mating-type loci provide initial self/non-self-recognition through pheromone and receptor interactions t...

  • Article
  • Open Access
16 Citations
3,386 Views
17 Pages

30 September 2019

Nitrogen use efficiency (NUE) of crops is estimated to be less than 50%, with a strong impact on environment and economy. Genotype-dependent ability to cope with N shortage has been only partially explored in maize and, in this context, the compariso...

  • Article
  • Open Access
28 Citations
4,641 Views
22 Pages

Genome-Wide Identification and Functional Analysis of Nitrate Transporter Genes (NPF, NRT2 and NRT3) in Maize

  • Lihua Jia,
  • Desheng Hu,
  • Junbo Wang,
  • Yuanyuan Liang,
  • Fang Li,
  • Yi Wang and
  • Yanlai Han

18 August 2023

Nitrate is the primary form of nitrogen uptake in plants, mainly transported by nitrate transporters (NRTs), including NPF (NITRATE TRANSPORTER 1/PEPTIDE TRANSPORTER FAMILY), NRT2 and NRT3. In this study, we identified a total of 78 NPF, seven NRT2,...

  • Article
  • Open Access
28 Citations
4,458 Views
15 Pages

Identification of Long Non-Coding RNAs and the Regulatory Network Responsive to Arbuscular Mycorrhizal Fungi Colonization in Maize Roots

  • Guomin Han,
  • Chen Cheng,
  • Yanmei Zheng,
  • Xuewen Wang,
  • Yunjian Xu,
  • Wei Wang,
  • Suwen Zhu and
  • Beijiu Cheng

11 September 2019

Recently, long noncoding RNAs (lncRNAs) have emerged as vital regulators of many biological processes in animals and plants. However, to our knowledge no investigations on plant lncRNAs which respond to arbuscular mycorrhizal (AM) fungi have been rep...

  • Article
  • Open Access
7 Citations
2,885 Views
20 Pages

Genome-Wide Survey of the RWP-RK Gene Family in Cassava (Manihot esculenta Crantz) and Functional Analysis

  • Chenyu Lin,
  • Xin Guo,
  • Xiaohui Yu,
  • Shuxia Li,
  • Wenbin Li,
  • Xiaoling Yu,
  • Feng An,
  • Pingjuan Zhao and
  • Mengbin Ruan

18 August 2023

The plant-specific RWP-RK transcription factor family plays a central role in the regulation of nitrogen response and gametophyte development. However, little information is available regarding the evolutionary relationships and characteristics of th...

  • Article
  • Open Access
13 Citations
3,798 Views
19 Pages

Identification and Molecular Characterization of RWP-RK Transcription Factors in Soybean

  • Nooral Amin,
  • Naveed Ahmad,
  • Mohamed A. S. Khalifa,
  • Yeyao Du,
  • Ajmal Mandozai,
  • Aimal Nawaz Khattak and
  • Wang Piwu

31 January 2023

The RWP-RK is a small family of plant-specific transcription factors that are mainly involved in nitrate starvation responses, gametogenesis, and root nodulation. To date, the molecular mechanisms underpinning nitrate-regulated gene expression in man...

  • Article
  • Open Access
11 Citations
2,847 Views
21 Pages

Genome-Wide Identification and Functional Characterization Reveals the Pivotal Roles of BnaA8.ATG8F in Salt Stress Tolerance and Nitrogen Limitation Adaptation in Allotetraploid Rapeseed

  • Tianyu Zhang,
  • Ting Zhou,
  • Yifan Zhang,
  • Junfan Chen,
  • Haili Song,
  • Pengjia Wu,
  • Caipeng Yue,
  • Jinyong Huang,
  • Zhenhua Zhang and
  • Yingpeng Hua

26 September 2022

Autophagy is a common physiological process in organisms, including higher plants. The ATG8 subfamily, the core member of the autophagy-related gene (ATG) family, plays a key role in plant growth and development and nutrient stress responses. However...

  • Article
  • Open Access
46 Citations
5,552 Views
23 Pages

22 February 2020

Nitrogen (N) is the most important limiting factor for cotton production worldwide. Genotype-dependent ability to cope with N shortage has been only partially explored in cotton, and in this context, the comparison of molecular responses of cotton ge...

  • Article
  • Open Access
2 Citations
1,962 Views
15 Pages

30 November 2023

Long non-coding RNAs (lncRNAs) regulate gene expression in eukaryotic organisms. Research suggests that lncRNAs may be involved in the regulation of nitrogen use efficiency in plants. In this study, we identified 1628 lncRNAs based on the transcripto...

  • Article
  • Open Access
2 Citations
3,171 Views
17 Pages

A Genome-Wide Association Study to Identify Novel Candidate Genes Related to Low-Nitrogen Tolerance in Cucumber (Cucumis sativus L.)

  • Bowen Li,
  • Aimin Wei,
  • Xueqiang Tong,
  • Yike Han,
  • Nan Liu,
  • Zhengwu Chen,
  • Hongyu Yang,
  • Huaxiang Wu,
  • Mingjie Lv and
  • Shengli Du
  • + 1 author

6 March 2023

Cucumber is one of the most important vegetables, and nitrogen is essential for the growth and fruit production of cucumbers. It is crucial to develop cultivars with nitrogen limitation tolerance or high nitrogen efficiency for green and efficient de...

  • Article
  • Open Access
3 Citations
2,080 Views
10 Pages

23 September 2024

Background/Objectives: Nitrogen is an essential macroelement for plant growth and productivity. Calcium (Ca2+) acts as a critical second messenger in numerous adaptations and developmental processes in plants. The Calcineurin B-like protein (CBL)-int...

  • Article
  • Open Access
16 Citations
6,305 Views
14 Pages

Starch Rich Chlorella vulgaris: High-Throughput Screening and Up-Scale for Tailored Biomass Production

  • Giorgia Carnovale,
  • Filipa Rosa,
  • Volha Shapaval,
  • Simona Dzurendova,
  • Achim Kohler,
  • Trude Wicklund,
  • Svein Jarle Horn,
  • Maria J. Barbosa and
  • Kari Skjånes

28 September 2021

The use of microalgal starch has been studied in biorefinery frameworks to produce bioethanol or bioplastics, however, these products are currently not economically viable. Using starch-rich biomass as an ingredient in food applications is a novel wa...

  • Review
  • Open Access
9 Citations
4,054 Views
12 Pages

A Review: Systemic Signaling in the Regulation of Plant Responses to Low N, P and Fe

  • Zhi Geng,
  • Jun Chen,
  • Bo Lu,
  • Fuyuan Zhang,
  • Ziping Chen,
  • Yujun Liu,
  • Chao Xia,
  • Jing Huang,
  • Cankui Zhang and
  • Congshan Xu
  • + 1 author

25 July 2023

Plant signal transduction occurs in response to nutrient element deficiency in plant vascular tissue. Recent works have shown that the vascular tissue is a central regulator in plant growth and development by transporting both essential nutritional a...

  • Article
  • Open Access
15 Citations
4,913 Views
15 Pages

26 April 2019

Medium-chain-length polyhydroxyalkanoates (mcl-PHAs) have gained great attention as a new green alternative to petrochemical-derived polymers. Due to their outstanding material properties they can be used in a wide range of applications. Pseudomonas...

  • Article
  • Open Access
3 Citations
2,417 Views
15 Pages

8 March 2024

The phytopathogenic fungus Fusarium fujikuroi has a rich secondary metabolism which includes the synthesis of very different metabolites in response to diverse environmental cues, such as light or nitrogen. Here, we focused our attention on fusarins,...

  • Article
  • Open Access
966 Views
19 Pages

19 September 2025

Nitrogen (N) is the most important macro-nutrient for plant growth and development, which not only results in the highest cost in crop production but may also lead to environmental pollution. Hence, there is a need to develop N and use efficient geno...

  • Article
  • Open Access
5 Citations
2,453 Views
14 Pages

The Multikinase Inhibitor AD80 Induces Mitotic Catastrophe and Autophagy in Pancreatic Cancer Cells

  • Keli Lima,
  • Lívia Bassani Lins de Miranda,
  • Anali Del Milagro Bernabe Garnique,
  • Bruna Oliveira de Almeida,
  • Mariane Cristina do Nascimento,
  • Guilherme Augusto Sousa Alcântara,
  • Glaucia Maria Machado-Santelli,
  • Eduardo Magalhães Rego and
  • João Agostinho Machado-Neto

29 July 2023

Significant advances in understanding the molecular complexity of the development and progression of pancreatic cancer have been made, but this disease is still considered one of the most lethal human cancers and needs new therapeutic options. In the...

  • Article
  • Open Access
7 Citations
2,815 Views
12 Pages

MoWhi2 Mediates Mitophagy to Regulate Conidiation and Pathogenesis in Magnaporthe oryzae

  • Shuai Meng,
  • Jane Sadhna Jagernath,
  • Chaoxi Luo,
  • Huanbin Shi and
  • Yanjun Kou

Mitophagy refers to the specific process of degrading mitochondria, which is an important physiological process to maintain the balance of mitochondrial quantity and quality in cells. At present, the mechanisms of mitophagy in pathogenic fungi remain...

  • Article
  • Open Access
12 Citations
3,581 Views
22 Pages

12 October 2021

Nitrogen (N) is an essential macronutrient for plants. However, little is known about the molecular regulation of N assimilation in Brassica napus, one of the most important oil crops worldwide. Here, we carried out a comprehensive genome-wide analys...

  • Article
  • Open Access
19 Citations
3,250 Views
22 Pages

26 September 2021

Nuclear Factor-Y (NF-Y) transcription factors play vital roles in plant abiotic stress response. Here, the NF-Y family in Brassica napus, which is hyper-sensitive to nitrogen (N) deprivation, was comprehensively identified and systematically characte...

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