94 Results Found

Porous dielectric membranes that perform insulator-based dielectrophoresis or electroosmotic pumping are commonly used in microchip technologies. However, there are few fundamental studies on the electrokinetic flow patterns of single microparticles...

Dielectrophoresis (DEP) is an advanced microfluidic manipulation technique that is based on the interaction of polarized particles with the spatial gradient of a non-uniform electric field to achieve non-contact and highly selective manipulation of p...

The micropipette manipulation technique is capable of making fundamental single particle measurements and analyses. This information is critical for establishing processing parameters in systems such as microfluidics and homogenization. To demonstrat...

We present in this paper a revision of three different methods we conceived in the framework of liquid crystal on silicon (LCoS) display optimization and application. We preliminarily demonstrate an LCoS self-calibration technique, from which we can...

Microfluidic microparticle manipulation is currently widely used in environmental, bio-chemical, and medical applications. Previously we proposed a straight microchannel with additional triangular cavity arrays to manipulate microparticles with inert...

Non-contact manipulation technology has a wide range of applications in the manipulation and fabrication of micro/nanomaterials. However, the manipulation devices are often complex, operated only by professionals, and limited by a single manipulation...

(1) The advent of micro/nanorobotics promises to transform the physical, chemical, and biological domains by harnessing opportunities otherwise limited by size. Most notable is the biomedical field, in which the ability to manipulate micro/nanopartic...

This paper introduces a dielectrophoretic system for the manipulation and separation of microparticles. The system is composed of five layers and utilizes microarray dot electrodes. We validated our system by conducting size-dependent manipulation an...

Micro/nano-manipulation is the fabrication of particular constructs on devices at the micro/nano-scale. Precise manipulation of microparticles is one of the key technological difficulties in manufacturing micro/nano-scale components. Based on scannin...

Currently used planar manipulation methods that utilize oscillating surfaces are usually based on asymmetries of time, kinematic, wave, or power types. This paper proposes a method for omnidirectional manipulation of microparticles on a platform subj...

A method incorporating the optically induced electrorotation (OER) and alternating current electroosmotic (ACEO) effects, for the formation and motion control of microparticle chains, is numerically and experimentally demonstrated. In this method, bo...

Size sorting, line focusing, and isolation of microparticles or cells are fundamental ingredients in the improvement of disease diagnostic tools adopted in biology and biomedicine. Microfluidic devices are exploited as a solution to transport and man...

Arranging microparticles into desired patterns, especially in a complicated pattern with a reliable and tunable manner, is challenging but highly desirable in the fields such as biomedicine and tissue engineering. To overcome these limitations, here,...

Local illumination with a light beam leads to thermo-orientational processes in a frustrated chiral nematic film with a free surface. Light-induced hydrodynamic flow and orientational structure create an adaptive platform for the collection, translat...

Metallic structures can be used for the localized heating of fluid and the controlled generation of microfluidic currents. Carefully designed currents can move and trap small particles and cells. Here we demonstrate a new bi-metallic substrate that a...

Medical ultrasound technology is available, affordable, and non-invasive. It is used to detect, quantify, and heat tissue structures. This review article gives a concise overview of the types of behaviour that biological cells experience under the in...

Microfluidics is an important technology for the biomedical industry and is often utilised in our daily lives. Recent advances in micro-milling technology have allowed for rapid fabrication of smaller and more complex structures, at lower costs, maki...

In order to study the acoustic levitation and manipulation of micro-particles in the heterogeneous structures inside metal, a test system for internal levitation in three-dimensional space is designed, establishing the 3D motion model of ultrasonic l...

Controllable assembly in nano-/microscale holds considerable promise for bioengineering, intracellular manipulation, diagnostic sensing, and biomedical applications. However, up to now, micro-/nanoscopic assembly methods are severely limited by the f...

Inertial microfluidics has obtained attention for its good performance in microparticle manipulation. It has the advantages of simplicity, high throughput, and a lack of external fields. In this paper, a simple microfluidic device is described, which...

In biomedical diagnosis, the efficient separation and purification of specific targets from clinical samples is the desired first step. Herein, the concept of virtual filter membranes based on optically-induced dielectrophoresis (ODEP) manipulation i...

Acoustic manipulation of microparticles and cells has attracted growing interest in biomedical applications. In particular, the use of acoustic waves to concentrate particles plays an important role in enhancing the detection process by biosensors. H...

Droplet microfluidics can produce highly tailored microparticles whilst retaining monodispersity. However, these systems often require lengthy optimisation, commonly based on a trial-and-error approach, particularly when using bio-instructive, polyme...

Inertial Microfluidics offer a high throughput, label-free, easy to design, and cost-effective solutions, and are a promising technique based on hydrodynamic forces (passive techniques) instead of external ones, which can be employed in the lab-on-a-...

High-efficient separation of (bio)microparticles has important applications in chemical analysis, environmental monitoring, drug screening, and disease diagnosis and treatment. As a label-free and high-precision separation scheme, dielectrophoresis (...

Shape-memory polymers have seen tremendous research efforts driven by the need for better drug carries and biomedical devices. In contrast to these advancements, fabrication of shape-memory particles which actuate at body temperature remains scarce....

The timely detection and diagnosis of diseases and accurate monitoring of specific genetic conditions require rapid and accurate separation, sorting, and direction of target cell types toward a sensor device surface. In that regard, cellular manipula...

Cardiovascular diseases such as hypertension and cardiac failure in South African children and adolescents are effectively managed long term, using a combination treatment of captopril and hydrochlorothiazide. The majority of commercially available p...

Methods for the isolation and analysis of extracellular vesicles (EVs) have been extensively explored in the field of life science and in clinical diagnosis in recent years. The separation and efficient recovery of high-purity target EVs from biologi...

Photopolymerized microparticles are made of biocompatible hydrogels like Polyethylene Glycol Diacrylate (PEGDA) by using microfluidic devices are a good option for encapsulation, transport and retention of biological or toxic agents. Due to the diffe...

We theoretically study the impact of bismuth-chalcogenide microparticles on the linear absorption and dispersion properties of a four-level double-V-type quantum system. The quantum system interacts with two circularly polarized laser fields of the s...

Optoelectronic tweezers (OET) are a promising technique for the realization of reconfigurable systems suitable to trap and manipulate microparticles. In particular, dielectrophoretic (DEP) forces produced by OET represent a valid alternative to micro...

Non-spherical shape is a general appearance feature for bioparticles. Therefore, a mechanical mechanism study of non-spherical particle migration in a microfluidic chip is essential for more precise isolation of target particles. With the manipulatio...

In recent years, various devices utilizing surface acoustic waves (SAW) have emerged as powerful tools for manipulating particles and fluids in microchannels. Although they demonstrate a wide range of functionalities across diverse applications, exis...

Optical tweezers can manipulate micro-particles, which have been widely used in various applications. Here, we experimentally demonstrate that optical tweezers can assemble the micro-particles to form stable structures at the glass–solution interface...

This work proposes a multi-objective polydimethylsiloxane (PDMS) micro-optofluidic (MoF) device suitably designed and manufactured through a 3D-printed-based master–slave approach. It exploits optical detection techniques to characterize immisc...

We introduce and investigate a novel Laguerre-Gaussian (LG) beam, different from the conventional modal LG beams, which conserve the transverse intensity structure (up to scale) on propagation. The proposed beam does not conserve its structure on fre...

Using tight focusing light, optical tweezers (OT) are tools that can manipulate and capture microscopic particles and biological cells as well as characterize a wide range of micro and nanomaterials. In this paper, we focused on fibroblasts, which ar...

The aim of the work was to design and construct a microscopic stage that enables the observation of biological cells in a magnetic field with a constant magnetic force. Regarding the requirements for biological observations in the magnetic field, con...

Manipulation of particles at the surface of a droplet can lead to the formation of structures with heterogeneous surfaces, including patchy colloidal capsules or patchy particles. Here, we study the assembly and rearrangement of microparticles confin...

We report observation and manipulation of a capillary jet under ultra-high centrifugal gravity in a proposed capillary-based fluidic device for the synthesis of microparticles in a centrifugal tube called Centrifuge-Based Droplet Shooting Device (CDS...

Rotation and transportation of micro-particles using ultrasonically-driven devices shows promising applications in the fields of biological engineering, composite material manufacture, and micro-assembly. Current interest in mechanical effects of ult...

Acoustic radiation forces have been extensively studied regarding static particles, cell patterning, and dynamic transportation. Compared with standing wave manipulation, traveling wave manipulation can be more easily modulated in real time and has n...

We investigate maneuvering superparamagnetic microparticles, or beads, in a remotely-controlled, automated way across arrays of few-micron-diameter permalloy disks. This technique is potentially useful for applying tunable forces to or for sorting bi...

Microfluidic devices can provide innovative means to handle and control the transport of (bio)particles within a fluid flow. The advantage of microscale devices is that different components can be integrated in a single chip at low cost, with a negli...

Precise trap and manipulation of individual cells is a prerequisite for single-cell analysis, which has a wide range of applications in biology, chemistry, medicine, and materials. Herein, a microfluidic trapping system with a 3D electrode based on A...

Self-propelling micro/nano-motors have attracted great attention due to their controllable active motion and various functional attributes. To date, a variety of technologies have been reported for the fabrication of micro/nano-motors. However, there...

Based on the Fourier transform (FT) of surface plasmon polaritons (SPPs), the relation between the displacement of the plasmonic field and the spatial frequency of the excitation light is theoretically established. The SPPs’ field shifts transv...

Optical fiber tweezers have been gaining prominence in several applications in Biology and Medicine. Due to their outstanding focusing abilities, they are able to trap and manipulate microparticles, including cells, needing any physical contact and w...

In this paper, we report a new kind of beam, named “spoon-like” beams, generated with the exponential phase. The intensity distributions and transverse energy flow of the spoon-like beam at the focal plane are analyzed theoretically and experimentall...