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Open AccessArticle

Dielectrophoretic Manipulation and Separation of Microparticles Using Microarray Dot Electrodes

1
Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia
2
Centre for Innovation in Medical Engineering (CIME), Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia
*
Author to whom correspondence should be addressed.
Sensors 2014, 14(4), 6356-6369; https://doi.org/10.3390/s140406356
Received: 15 November 2013 / Revised: 7 March 2014 / Accepted: 14 March 2014 / Published: 3 April 2014
(This article belongs to the Special Issue Microarray Sensors)
This paper introduces a dielectrophoretic system for the manipulation and separation of microparticles. The system is composed of five layers and utilizes microarray dot electrodes. We validated our system by conducting size-dependent manipulation and separation experiments on 1, 5 and 15 μm polystyrene particles. Our findings confirm the capability of the proposed device to rapidly and efficiently manipulate and separate microparticles of various dimensions, utilizing positive and negative dielectrophoresis (DEP) effects. Larger size particles were repelled and concentrated in the center of the dot by negative DEP, while the smaller sizes were attracted and collected by the edge of the dot by positive DEP. View Full-Text
Keywords: dielectrophoresis (DEP); microparticle separation; dot electrode; microfluidics; BioMEMS dielectrophoresis (DEP); microparticle separation; dot electrode; microfluidics; BioMEMS
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MDPI and ACS Style

Yafouz, B.; Kadri, N.A.; Ibrahim, F. Dielectrophoretic Manipulation and Separation of Microparticles Using Microarray Dot Electrodes. Sensors 2014, 14, 6356-6369.

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