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1,488 Results Found

  • Feature Paper
  • Article
  • Open Access
28 Citations
5,940 Views
10 Pages

Scandium Recovery from an Ammonium Fluoride Strip Liquor by Anti-Solvent Crystallization

  • Şerif Kaya,
  • Edward Michael Peters,
  • Kerstin Forsberg,
  • Carsten Dittrich,
  • Srecko Stopic and
  • Bernd Friedrich

26 September 2018

In this study, the crystallization of scandium from ammonium fluoride strip liquor, obtained by solvent extraction, was investigated using an anti-solvent crystallization technique. Acetone, ethanol, methanol and isopropanol were added individually t...

  • Review
  • Open Access
172 Citations
36,641 Views
21 Pages

Anti-Solvent Crystallization Strategies for Highly Efficient Perovskite Solar Cells

  • Maria Konstantakou,
  • Dorothea Perganti,
  • Polycarpos Falaras and
  • Thomas Stergiopoulos

28 September 2017

Solution-processed organic-inorganic halide perovskites are currently established as the hottest area of interest in the world of photovoltaics, ensuring low manufacturing cost and high conversion efficiencies. Even though various fabrication/deposit...

  • Article
  • Open Access
10 Citations
4,171 Views
17 Pages

Modeling the Production Process of Lignin Nanoparticles Through Anti-Solvent Precipitation for Properties Prediction

  • Victor Girard,
  • Laurent Marchal-Heussler,
  • Hubert Chapuis,
  • Nicolas Brosse,
  • Nadia Canilho and
  • Isabelle Ziegler-Devin

6 November 2024

Global warming has recently intensified research interest in renewable polymer chemistry, with significant attention directed towards lignin nanoparticle (LNP) synthesis. Despite progress, LNP industrial application faces challenges: (1) reliance on...

  • Article
  • Open Access
1 Citations
3,405 Views
26 Pages

Application of Anti-Solvent Crystallization for High-Purity Potash Production from K-Feldspar Leaching Solution

  • Sina Shakibania,
  • Lena Sundqvist-Öqvist,
  • Jan Rosenkranz and
  • Yousef Ghorbani

3 July 2024

Potassium-containing feldspars provide a high potential for producing potash, a product with widespread use in agriculture. The present work assesses applying the anti-solvent crystallization method for the purification and recovery of high-purity mu...

  • Article
  • Open Access
18 Citations
8,213 Views
13 Pages

18 November 2019

Solvent engineering is one of the most widely applied preparation methods for the high- quality perovskite films. In this method, the choice of anti-solvent plays a very important role to improve the perovskite crystal quality. Here, we report a faci...

  • Article
  • Open Access
10 Citations
8,277 Views
13 Pages

17 January 2019

Clopidogrel bisulfate (CLP) form-I crystals are irregular, rectangular-shaped crystals. Because of their poor compressibility, flowability and their strong surface tension, manufacturers apply spherical crystallization methods to produce CLP form-I s...

  • Article
  • Open Access
25 Citations
5,702 Views
14 Pages

This study aimed to investigate the role of micellization of sodium lauryl sulfate (SLS) in poloxamer 407 (POX)-based solid dispersions (POX-based SDs) using the anti-solvent method in enhancing the dissolution rate of practically water-insoluble cil...

  • Article
  • Open Access
38 Citations
4,626 Views
15 Pages

Improvement of Enzymatic Saccharification and Ethanol Production from Rice Straw Using Recycled Ionic Liquid: The Effect of Anti-Solvent Mixture

  • Santi Chuetor,
  • Elizabeth Jayex Panakkal,
  • Thanagorn Ruensodsai,
  • Kraipat Cheenkachorn,
  • Suchata Kirdponpattara,
  • Yu-Shen Cheng and
  • Malinee Sriariyanun

One of the major concerns for utilizing ionic liquid on an industrial scale is the cost involved in the production. Despite its proven pretreatment efficiency, expenses involved in its usage hinder its utilization. A better way to tackle this limitat...

  • Article
  • Open Access
1 Citations
1,131 Views
12 Pages

1 September 2025

Regulating the crystallization dynamics of perovskite films is key to improving the efficiency and operational stability of (FA0.83MA0.17Cs0.05)Pb(I0.85Br0.15)3 perovskite solar cells (PSCs). However, precise regulation of the crystallization process...

  • Review
  • Open Access
45 Citations
3,812 Views
21 Pages

Solid multicomponent systems (SMS) are gaining an increasingly important role in the pharmaceutical industry, to improve the physicochemical properties of active pharmaceutical ingredients (APIs). In recent years, various processes have been employed...

  • Article
  • Open Access
1 Citations
1,385 Views
12 Pages

29 January 2025

The reverse addition process in anti-solvent crystallization is safer and more efficient than sieving when dealing with energetic compounds. A new mathematical model has been developed to understand the crystal size mechanism during the reverse addit...

  • Article
  • Open Access
28 Citations
6,155 Views
16 Pages

27 November 2020

Gold nanoparticles (GNPs) are commonly synthesized using the Turkevich method, but there are limitations on the maximum concentration of gold nanoparticles that can be achieved using this method (often < 1 mM (=0.34 mg/mL) gold precursor loading)....

  • Article
  • Open Access
2 Citations
3,133 Views
8 Pages

31 July 2022

Since perovskite materials are currently mostly used in the active layer of solar cells, how to maximize the conversion efficiency of the active layer is the most urgent problem at present. In this regard, the extremely low voltage loss and tunable e...

  • Article
  • Open Access
32 Citations
5,638 Views
15 Pages

Antioxidant, Anti-Inflammatory, and Antibacterial Properties of an Achillea millefolium L. Extract and Its Fractions Obtained by Supercritical Anti-Solvent Fractionation against Helicobacter pylori

  • Marisol Villalva,
  • Jose Manuel Silvan,
  • Teresa Alarcón-Cavero,
  • David Villanueva-Bermejo,
  • Laura Jaime,
  • Susana Santoyo and
  • Adolfo J. Martinez-Rodriguez

20 September 2022

The main objective of this work is to evaluate the potential utility of an Achillea millefolium extract (yarrow extract, YE) in the control of H. pylori infection. The supercritical anti-solvent fractionation (SAF) process of YE allowed the obtaining...

  • Article
  • Open Access
12 Citations
3,307 Views
10 Pages

9 March 2024

A facile and low-cost strategy to fabricate CsPbBr3 single crystals is essential for developing perovskite optoelectronic devices. Herein, we have presented a room temperature anti-solvent precipitate method for growing sub-centimeter-sized CsPbBr3 s...

  • Article
  • Open Access
6 Citations
4,009 Views
20 Pages

Optimizing Paclitaxel Oral Absorption and Bioavailability: TPGS Co-Coating via Supercritical Anti-Solvent Fluidized Bed Technology

  • Zicheng Zhong,
  • Yanling Lan,
  • Jinxing Chen,
  • Lu Ping,
  • Xuchun Li,
  • Qing Wang,
  • Xiaodong Zhuang,
  • Zhenwen Qiu,
  • Tianhui Yuan and
  • Dandong Luo
  • + 3 authors

25 March 2024

Supercritical anti-solvent fluidized bed (SAS-FB) coating technology has the advantages of reducing particle size, preventing high surface energy particle aggregation, improving the dissolution performance and bioavailability of insoluble drugs. The...

  • Article
  • Open Access
4 Citations
3,249 Views
11 Pages

19 January 2022

All-inorganic metal halide perovskite nanocrystals (IPeNCs) have become one of the most promising luminescent materials for next-generation display and lighting technology owing to their excellent color expression ability. However, research on IPeNCs...

  • Article
  • Open Access
10 Citations
8,575 Views
17 Pages

Preparation and Characterization of Tripterygium wilfordii Multi-Glycoside Nanoparticle Using Supercritical Anti-Solvent Process

  • Fengli Chen,
  • Tong Li,
  • Shuangyang Li,
  • Kexin Hou,
  • Zaizhi Liu,
  • Lili Li,
  • Guoqiang Cui,
  • Yuangang Zu and
  • Lei Yang

17 February 2014

The aim of this study was to prepare nanosized Tripterygium wilfordii multi-glycoside (GTW) powders by the supercritical antisolvent precipitation process (SAS), and to evaluate the anti-inflammatory effects. Ethanol was used as solvent and carbon di...

  • Article
  • Open Access
2 Citations
2,813 Views
13 Pages

Antisolvent Engineering to Enhance Photovoltaic Performance of Methylammonium Bismuth Iodide Solar Cells

  • Ming-Chung Wu,
  • Ching-Mei Ho,
  • Kai-Chi Hsiao,
  • Shih-Hsuan Chen,
  • Yin-Hsuan Chang and
  • Meng-Huan Jao

23 December 2022

High absorption ability and direct bandgap makes lead-based perovskite to acquire high photovoltaic performance. However, lead content in perovskite becomes a double-blade for counterbalancing photovoltaic performance and sustainability. Herein, we d...

  • Article
  • Open Access
12 Citations
2,724 Views
11 Pages

Naringenin Ultrafine Powder Was Prepared by a New Anti-Solvent Recrystallization Method

  • Xiaonan Zhang,
  • Yan Huang,
  • Yufei Shi,
  • Mengyu Chen,
  • Lubin Zhang,
  • Yimin An and
  • Zhiwei Liu

19 June 2022

Raw naringenin directly isolated from plants is significantly limited by its poor dissolution rate and low bioavailability for clinical and in vivo studies. This study reported a method for the preparation of naringenin ultrafine powder (NUP) using a...

  • Feature Paper
  • Article
  • Open Access
10 Citations
4,630 Views
12 Pages

2 January 2020

Anti-solvent crystallization is frequently applied in pharmaceutical processes for the separation and purification of intermediate compounds and active ingredients. The selection of optimal solvent types is important to improve the economic performan...

  • Feature Paper
  • Article
  • Open Access
1 Citations
1,012 Views
13 Pages

23 April 2025

All-inorganic CsPbX3 perovskites have significant potential for applications in the photovoltaic field. However, during their preparation, the slow evaporation rate of the precursor solution limits the extent of solution supersaturation, leading to p...

  • Article
  • Open Access
7 Citations
3,356 Views
19 Pages

13 March 2024

Amorphous solids exhibit enhanced solubility and dissolution rates relative to their crystalline counterparts. However, attaining optimal bioavailability presents a challenge, primarily due to the need to maintain the physical stability of amorphous...

  • Article
  • Open Access
8 Citations
4,040 Views
10 Pages

24 March 2023

We have investigated the effects of the methylammonium bromide (MABr) content of the precursor solution on the properties of wide-bandgap methylammonium lead tribromide (MAPbBr3) perovskite solar cells (PSCs). In addition, the anti-solvent process fo...

  • Article
  • Open Access
38 Citations
9,441 Views
18 Pages

In this work, the solubilities of pharmaceutical cocrystals in solvent/anti-solvent systems were predicted using PC-SAFT in order to increase the efficiency of cocrystal formation processes. Modeling results and experimental data were compared for th...

  • Article
  • Open Access
7 Citations
3,870 Views
14 Pages

2 February 2022

In this contribution, crystallization was performed to assess the kinetics of nucleation and crystal growth of L-lactide. In most common solvents, this compound shows very high solubility even at low temperatures, which could be challenging for cryst...

  • Article
  • Open Access
869 Views
18 Pages

Study on the Structure of a Novel CMS@C12H22O14Fe Suppressant and Its Mechanism of Inhibiting Coal Dust Deflagration

  • Yansong Zhang,
  • Yang Yang,
  • Jin Han,
  • Shengjing Dongye,
  • Fei Wang,
  • Wenjie Liu,
  • Lei Wang and
  • Yang Zhang

25 February 2025

Coal resources still occupy a dominant position in the energy consumption structure, and the prevention and control of coal dust explosion has become an important measure to ensure the safe production of coal. To this end, a new type of environmental...

  • Article
  • Open Access
35 Citations
5,965 Views
17 Pages

Comparison of Various Solvent Extracts and Major Bioactive Components from Portulaca oleracea for Antioxidant, Anti-Tyrosinase, and Anti-α-Glucosidase Activities

  • Wei-Cheng Chen,
  • Shih-Wei Wang,
  • Cai-Wei Li,
  • Hsiang-Ru Lin,
  • Chang-Syun Yang,
  • Yi-Cheng Chu,
  • Tzong-Huei Lee and
  • Jih-Jung Chen

16 February 2022

Portulaca oleracea is a well-known species for traditional medicine and food homology in Taiwan. In traditional medicine, P. oleracea is also used to treat gastrointestinal disorders, liver inflammation, fever, severe inflammation, and headaches. We...

  • Article
  • Open Access
12 Citations
6,065 Views
14 Pages

One-Step Method to Prepare PLLA Porous Microspheres in a High-Voltage Electrostatic Anti-Solvent Process

  • Ying Wang,
  • Li-Hui Zhu,
  • Ai-Zheng Chen,
  • Qiao Xu,
  • Yu-Juan Hong and
  • Shi-Bin Wang

13 May 2016

A one-step method using a high-voltage electrostatic anti-solvent process was employed to fabricate poly-l-lactide (PLLA) porous microspheres (PMs). To address the simplification and control of the preparation process, a 24 full factorial experiment...

  • Article
  • Open Access
11 Citations
3,200 Views
12 Pages

Theoretical Mechanism on the Cellulose Regeneration from a Cellulose/EmimOAc Mixture in Anti-Solvents

  • Zhaoyang Ju,
  • Yihang Yu,
  • Shaokeng Feng,
  • Tingyu Lei,
  • Minjia Zheng,
  • Liyong Ding and
  • Mengting Yu

2 February 2022

The experiments on cellulose dissolution/regeneration have made some achievements to some extent, but the mechanism of cellulose regeneration in ionic liquids (ILs) and anti-solvent mixtures remains elusive. In this work, the cellulose regeneration m...

  • Review
  • Open Access
27 Citations
18,303 Views
25 Pages

Growth of Metal Halide Perovskite, from Nanocrystal to Micron-Scale Crystal: A Review

  • Haijiao Harsan Ma,
  • Muhammad Imran,
  • Zhiya Dang and
  • Zhaosheng Hu

24 April 2018

Metal halide perovskite both in the form of nanocrystal and thin films recently emerged as the most promising semiconductor material covering a huge range of potential applications from display technologies to photovoltaics. Colloidal inorganic and o...

  • Article
  • Open Access
3 Citations
2,344 Views
9 Pages

10 January 2023

Hierarchical organic structures have gained vast attention in the past decade owing to their great potential in chemical and medical applications in industries such as the food and pharmaceutical industries. In this paper, the crystallization of L-gl...

  • Article
  • Open Access
4 Citations
3,312 Views
17 Pages

To optimize the characteristics of stereocomplex polylactide-b-polyethylene glycol nanoparticles (SC-PEG NPs) in terms of pharmacokinetics (PK), we chose continuous anti-solvent precipitation with a T-junction as a preparation method and investigated...

  • Article
  • Open Access
15 Citations
4,645 Views
19 Pages

14 February 2022

The rhizome of Anemarrhena asphodeloides Bunge (AA, family Liliaceae) is a famous and frequently used herbal drug in the traditional medicine of Northeast Asia, under vernacular name “zhimu”. A. asphodeloides has been used as an anti-infl...

  • Article
  • Open Access
1 Citations
4,553 Views
13 Pages

Electrophoretic Deposition of Rochelle Salt Nanocrystals on Aluminum Plate

  • Rostislav Rusev,
  • Boriana Tzaneva and
  • George Angelov

10 June 2023

A straightforward and inexpensive electrophoretic method for obtaining environment-friendly nanocrystalline piezo layers from Rochelle salt (RS) is presented here. The electrophoretic deposition process includes the formation of nanocrystals by preci...

  • Article
  • Open Access
40 Citations
5,807 Views
15 Pages

Antioxidant and Anti-α-Glucosidase Activities of Various Solvent Extracts and Major Bioactive Components from the Fruits of Crataegus pinnatifida

  • Yen-Ting Lin,
  • Hsiang-Ru Lin,
  • Chang-Syun Yang,
  • Chia-Ching Liaw,
  • Ping-Jyun Sung,
  • Yueh-Hsiung Kuo,
  • Ming-Jen Cheng and
  • Jih-Jung Chen

6 February 2022

Crataegus pinnatifida is used to treat various diseases, including indigestion, congestive heart failure, hypertension, atherosclerosis, and myocardial dysfunction. We evaluated antioxidant and anti-α-glucosidase activities of various solvent e...

  • Article
  • Open Access
5 Citations
1,758 Views
19 Pages

12 February 2025

Spiropyran has an attractive and mysterious fluorescence switch and dual-color conversion characteristics, as it exhibits both aggregation-caused quenching (ACQ) in solvents and fluorescence enhancement in polymer matrices. The explanation for this p...

  • Article
  • Open Access
10 Citations
3,472 Views
15 Pages

11 June 2024

Curcumin is a naturally occurring hydrophobic polyphenolic compound with a rapid metabolism, poor absorption, and low stability, which severely limits its bioavailability. Here, we employed a starch–protein-based nanoparticle approach to improv...

  • Article
  • Open Access
2 Citations
1,779 Views
15 Pages

14 October 2024

CsPbIBr2, with its suitable bandgap, shows great potential as the top cell in tandem solar cells. Nonetheless, its further development is hindered by a high defect density, severe carrier recombination, and poor stability. In this study, CsPbI1.5Br1....

  • Article
  • Open Access
29 Citations
4,458 Views
12 Pages

8 November 2020

Myristica fragrans is a well-known species for flavoring many food products and for formulation of perfume and medicated balm. It is also used to treat indigestion, stomach ulcers, liver disorders, and, as emmenagogue, diaphoretic, diuretic, nervine,...

  • Article
  • Open Access
5 Citations
2,799 Views
9 Pages

30 November 2022

Perovskite light-emitting diodes (PeLEDs) have attracted extensive attention due to their advantages such as low-temperature solution processing, high photoluminescence quantum efficiency, high color purity, tunable wavelength, and excellent carrier...

  • Proceeding Paper
  • Open Access
1 Citations
2,096 Views
8 Pages

Currently, one of the key challenges in the pharmaceutical industry is the transformation of traditional batch production methods into robust continuous processes with the intention of reducing manufacturing costs and time and improving product quali...

  • Article
  • Open Access
10 Citations
3,404 Views
17 Pages

18 October 2022

Auricularia auricula-judae polysaccharide (AAP)-based nanoparticles (NPs) prepared via an anti-solvent precipitation approach were studied. Response surface methodology (RSM) design was carried out on the basis of single factor experiments, using ave...

  • Article
  • Open Access
45 Citations
6,727 Views
14 Pages

Enhanced Stability and Oral Bioavailability of Cannabidiol in Zein and Whey Protein Composite Nanoparticles by a Modified Anti-Solvent Approach

  • Ce Wang,
  • Jia Wang,
  • Yonghai Sun,
  • Kalev Freeman,
  • Monique Alyssa Mchenry,
  • Cuina Wang and
  • Mingruo Guo

27 January 2022

Wide applications of cannabidiol (CBD) in the food and pharmaceutical industries are limited due to its low bioavailability, sensitivity to environmental pressures and low water solubility. Zein nanoparticles were stabilized by whey protein (WP) for...

  • Article
  • Open Access
34 Citations
7,507 Views
18 Pages

Deep Eutectic Solvent Formulations and Alginate-Based Hydrogels as a New Partnership for the Transdermal Administration of Anti-Inflammatory Drugs

  • Sónia N. Pedro,
  • Maria S. M. Mendes,
  • Bruno M. Neves,
  • Isabel Filipa Almeida,
  • Paulo Costa,
  • Inês Correia-Sá,
  • Carla Vilela,
  • Mara G. Freire,
  • Armando J. D. Silvestre and
  • Carmen S. R. Freire

The transdermal administration of nonsteroidal anti-inflammatory drugs (NSAIDs) is a valuable and safer alternative to their oral intake. However, most of these drugs display low water solubility, which makes their incorporation into hydrophilic biop...

  • Article
  • Open Access
1 Citations
802 Views
18 Pages

5 November 2025

Background: Despite extensive phytochemical research on white tea varieties, flavonoid profiling in Baihao Yinzhen remains scarce. The development of green and efficient extraction methods is essential to facilitate its potential application in cosme...

  • Comment
  • Open Access
8 Citations
3,316 Views
6 Pages

Villalva et al. evaluated the potential utility of an Achillea millefolium (yarrow) extract in the control of H. pylori infection. The agar-well diffusions bioassay was applied to determine the antimicrobial activity of yarrow extracts. The supercrit...

  • Article
  • Open Access
15 Citations
3,792 Views
11 Pages

28 December 2022

In this study, bamboo pulp was simultaneously fibrillated and esterified in one-pot citric acid–choline chloride deep eutectic solvent treatment. The results indicated that increasing the temperature and time promoted esterification, yielding 0...

  • Article
  • Open Access
15 Citations
3,775 Views
22 Pages

Self-Healing, Solvent-Free, Anti-Corrosion Coating Based on Skin-like Polyurethane/Carbon Nanotubes Composites with Real-Time Damage Monitoring

  • Hui Kong,
  • Xiaomin Luo,
  • Peng Zhang,
  • Jianyan Feng,
  • Pengni Li,
  • Wenjie Hu,
  • Xuechuan Wang and
  • Xinhua Liu

26 December 2022

Self-healing anti-corrosion materials are widely regarded as a promising long-term corrosion protection strategy, and this is even more significant if the damage can be monitored in real-time and consequently repaired. Inspired by the hierarchical st...

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