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46 Results Found

  • Article
  • Open Access
622 Views
12 Pages

11 October 2025

The secularization of religion in late-nineteenth and early-twentieth-century Britain profoundly altered the ethical foundations of the modernist novel, challenging writers to reimagine the role of literature in the absence of religious authority. Ag...

  • Article
  • Open Access
1 Citations
1,295 Views
17 Pages

18 June 2025

In this article, I investigate the ontological status of the minor working-class character Mrs. McNab, the cleaner in “Time Passes", the middle section of Virginia Woolf’s tripartite novel To the Lighthouse. Woolf regarded this section as...

  • Editorial
  • Open Access
7 Citations
9,171 Views
8 Pages

In mid 2019, the author reminded the (International Society for Neonatal Screening) ISNS of the happy occasion of the 100th birthday of one of the living pioneers of neonatal screening, Professor Louis Isaac Woolf [...]

  • Article
  • Open Access
2,927 Views
15 Pages

In this article, an English professor and a sophomore-level English major explicate the singular difficulties of teaching and learning Virginia Woolf’s novel Mrs Dalloway mid-pandemic. These difficulties arise despite the fact that Mrs Dalloway...

  • Article
  • Open Access
25 Citations
6,577 Views
10 Pages

2 March 2019

The generation of concentration gradients is an essential part of a wide range of laboratory settings. However, the task usually requires tedious and repetitive steps and it is difficult to generate concentration gradients at once. Here, we present a...

  • Article
  • Open Access
781 Views
23 Pages

1 October 2025

Bisphenol A (BPA) is classified as an endocrine disruptor that mainly mimics the effects of estrogen and disrupts the synthesis of male androgens. Due to the toxicity of BPA, some new analogs, such as bisphenol BPB, BPC, BPF, PBH, and BPZ, were intro...

  • Editorial
  • Open Access
3 Citations
3,067 Views
4 Pages

One of the most dramatic discoveries in metabolic disease research was that of Ashbørn Følling, who in 1934, published his research outlining unusual biochemical findings in a set of siblings with severe developmental delay [...]

  • Article
  • Open Access
1 Citations
5,658 Views
16 Pages

18 December 2012

In this essay I would like to focus on “The Beast and the Sovereign”—and especially the Second Volume—as being something of an exception to Derrida’s usual hesitations about sovereignty. In other works, such as “Rogues”, Derrida displays a deep ambiv...

  • Article
  • Open Access
2,766 Views
22 Pages

2 September 2025

Mind wandering is a mental activity that occupies up to 50% of our waking time. While scientists have now started to acknowledge and to study the creative potential of mind wandering for our imaginative skills, fiction has long recognised its value....

  • Article
  • Open Access
7 Citations
3,163 Views
12 Pages

A Preliminary Study of Mild Heat Stress on Inflammasome Activation in Murine Macrophages

  • Simmie L. Foster,
  • Abigail J. Dutton,
  • Adina Yerzhan,
  • Lindsay B. March,
  • Katherine Barry,
  • Corey R. Seehus,
  • Xudong Huang,
  • Sebastien Talbot and
  • Clifford J. Woolf

19 April 2023

Inflammation and mitochondrial-dependent oxidative stress are interrelated processes implicated in multiple neuroinflammatory disorders, including Alzheimer’s disease (AD) and depression. Exposure to elevated temperature (hyperthermia) is propo...

  • Article
  • Open Access
1 Citations
1,934 Views
14 Pages

7 June 2023

One reason why the concept of the quotidian has proved elusive to critics of literature and the visual arts is that the commonplace in art and literature so often refuses to remain untransfigured, not least because of its power to confront us with th...

  • Article
  • Open Access
3 Citations
3,497 Views
17 Pages

14 March 2023

Background: Observational research implies a negative effect of having children on wellbeing. Objectives: To provide Mendelian randomisation evidence of the effect of having children on parental wellbeing. Design: Two-sample Mendelian randomisation....

  • Feature Paper
  • Article
  • Open Access
5 Citations
4,759 Views
14 Pages

Real Time Electronic Feedback for Improved Acoustic Trapping of Micron-Scale Particles

  • Charles P. Clark,
  • Vahid Farmehini,
  • Liam Spiers,
  • M. Shane Woolf,
  • Nathan S. Swami and
  • James P. Landers

21 July 2019

Acoustic differential extraction has been previously reported as a viable alternative to the repetitive manual pipetting and centrifugation steps for isolating sperm cells from female epithelial cells in sexual assault sample evidence. However, the e...

  • Article
  • Open Access
37 Citations
5,600 Views
16 Pages

A Revised Protocol for Culture of Airway Epithelial Cells as a Diagnostic Tool for Primary Ciliary Dyskinesia

  • Janice L. Coles,
  • James Thompson,
  • Katie L. Horton,
  • Robert A. Hirst,
  • Paul Griffin,
  • Gwyneth M. Williams,
  • Patricia Goggin,
  • Regan Doherty,
  • Peter M. Lackie and
  • Claire L. Jackson
  • + 6 authors

21 November 2020

Air–liquid interface (ALI) culture of nasal epithelial cells is a valuable tool in the diagnosis and research of primary ciliary dyskinesia (PCD). Ex vivo samples often display secondary dyskinesia from cell damage during sampling, infection or...

  • Feature Paper
  • Article
  • Open Access
7 Citations
5,156 Views
14 Pages

Closable Valves and Channels for Polymeric Microfluidic Devices

  • Charles P. Clark,
  • M. Shane Woolf,
  • Sarah L. Karstens,
  • Hannah M. Lewis,
  • Aeren Q. Nauman and
  • James P. Landers

27 June 2020

This study explores three unique approaches for closing valves and channels within microfluidic systems, specifically multilayer, centrifugally driven polymeric devices. Precise control over the cessation of liquid movement is achieved through either...

  • Feature Paper
  • Article
  • Open Access
5,251 Views
15 Pages

1 November 2019

Stevie Smith, one of the most productive of twentieth-century poets, is too often remembered simply as the coiner of the four-word punch line of a single short poem. This paper argues that her claim to be seen as a great writer depends on the major t...

  • Article
  • Open Access
11 Citations
8,371 Views
18 Pages

9 February 2021

Knee pain is an early sign of later incident radiographic knee osteoarthritis (OA). However, the prevalence of knee pain in the general population is unknown. Additionally, it is unknown how people with knee pain choose to self-manage the condition a...

  • Article
  • Open Access
9 Citations
3,793 Views
12 Pages

The Relationship between School Infrastructure and School Nutrition Program Participation and Policies in New York City

  • Melissa Pflugh Prescott,
  • Judith A. Gilbride,
  • Sean P. Corcoran,
  • Brian Elbel,
  • Kathleen Woolf,
  • Roland O. Ofori and
  • Amy Ellen Schwartz

School nutrition programs (SNP) provide much needed access to fruits, vegetables, and other healthy foods at low or no cost. Yet, the infrastructure of school kitchens and cafeteria vary across schools, potentially contributing to systematic barriers...

  • Article
  • Open Access
8 Citations
3,631 Views
18 Pages

The Impact on Parents of Diagnosing PCD in Young Children

  • Corine Driessens,
  • Siobhan Carr,
  • Edel Clough,
  • Fiona Copeland,
  • Sharon Dell,
  • Lucy Dixon,
  • Amanda Harris,
  • Rebecca Knibb,
  • Margaret Leigh and
  • Laura Behan
  • + 10 authors

16 August 2022

Primary ciliary dyskinesia (PCD) is an incurable, rare, inherited, chronic condition. Treatment includes the regular clearing of airway mucus, aggressive treatment of infections and management of hearing loss. Caregiver burden has not been explored,...

  • Review
  • Open Access
6 Citations
4,831 Views
17 Pages

Harnessing the Potential of Enzymes as Inhaled Therapeutics in Respiratory Tract Diseases: A Review of the Literature

  • Gilles Vanderstocken,
  • Nicholas L. Woolf,
  • Giuseppe Trigiante,
  • Jessica Jackson and
  • Rory McGoldrick

Respiratory tract diseases (RTDs) are a global cause of mortality and affect patient well-being and quality of life. Specifically, there is a high unmet need concerning respiratory tract infections (RTIs) due to limitations of vaccines and increased...

  • Article
  • Open Access
3 Citations
2,786 Views
15 Pages

Cross-Sectional Study of University Students’ Attitudes to ‘On Campus’ Delivery of COVID-19, MenACWY and MMR Vaccines and Future-Proofing Vaccine Roll-Out Strategies

  • Adam Webb,
  • Mayuri Gogoi,
  • Sarah Weidman,
  • Katherine Woolf,
  • Maria Zavala,
  • Shamez N. Ladhani,
  • Manish Pareek,
  • Lieve Gies and
  • Christopher D. Bayliss

10 August 2022

University students are a critical group for vaccination programmes against COVID-19, meningococcal disease (MenACWY) and measles, mumps and rubella (MMR). We aimed to evaluate risk factors for vaccine hesitancy and views about on-campus vaccine deli...

  • Article
  • Open Access
29 Citations
6,630 Views
9 Pages

26 August 2022

Mendelian randomisation (MR) is an increasingly popular method for strengthening causal inference in epidemiological studies. cis-MR in particular uses genetic variants in the gene region of a drug target protein as an instrumental variable to provid...

  • Review
  • Open Access
20 Citations
8,882 Views
13 Pages

9 May 2014

Primary ciliary dyskinesia (PCD) is a heterogeneous autosomal recessive condition affecting around 1:15,000. In people with PCD, microscopic motile cilia do not move normally resulting in impaired clearance of mucus and debris leading to repeated sin...

  • Communication
  • Open Access
11 Citations
7,086 Views
16 Pages

Holistics 3.0 for Health

  • David John Lary,
  • Steven Woolf,
  • Fazlay Faruque and
  • James P. LePage

Human health is part of an interdependent multifaceted system. More than ever, we have increasingly large amounts of data on the body, both spatial and non-spatial, its systems, disease and our social and physical environment. These data have a geosp...

  • Article
  • Open Access
11 Citations
10,607 Views
17 Pages

Nutrition Assessment of B-Vitamins in Highly Active and Sedentary Women

  • Kathleen Woolf,
  • Nicole L. Hahn,
  • Megan M. Christensen,
  • Amanda Carlson-Phillips and
  • Christine M. Hansen

26 March 2017

Background: Female athletes and active women require adequate nutrition for optimal health and performance. Nutrition assessments are needed to identify potential nutrients of concern. Folate, vitamin B6, and vitamin B12 function in important pathway...

  • Review
  • Open Access
1,729 Views
13 Pages

10 July 2025

Aging is a major non-modifiable risk factor for cardiovascular disease (CVD), in part due to its detrimental effects on vascular endothelial function. Dietary interventions, including those rich in plant-based components or following dietary patterns...

  • Communication
  • Open Access
11 Citations
9,763 Views
7 Pages

Caffeine Intake, Plasma Caffeine Level, and Kidney Function: A Mendelian Randomization Study

  • Alice Giontella,
  • Roxane de La Harpe,
  • Héléne T. Cronje,
  • Loukas Zagkos,
  • Benjamin Woolf,
  • Susanna C. Larsson and
  • Dipender Gill

18 October 2023

Caffeine is a psychoactive substance widely consumed worldwide, mainly via sources such as coffee and tea. The effects of caffeine on kidney function remain unclear. We leveraged the genetic variants in the CYP1A2 and AHR genes via the two-sample Men...

  • Review
  • Open Access
9 Citations
12,534 Views
36 Pages

11 December 2023

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder experienced by women. PCOS is a lifelong condition associated with reproductive, metabolic, and psychological presentations. PCOS is also linked with increased prevalence of cardi...

  • Article
  • Open Access
19 Citations
5,188 Views
14 Pages

Volatile Composition, Antimicrobial Activity, and In Vitro Innate Immunomodulatory Activity of Echinacea purpurea (L.) Moench Essential Oils

  • Noura S. Dosoky,
  • Liliya N. Kirpotina,
  • Igor A. Schepetkin,
  • Andrei I. Khlebnikov,
  • Brent L. Lisonbee,
  • Jeffrey L. Black,
  • Hillary Woolf,
  • Trever L. Thurgood,
  • Brittany L. Graf and
  • Mark T. Quinn
  • + 1 author

29 October 2023

Echinacea purpurea (L.) Moench is a medicinal plant commonly used for the treatment of upper respiratory tract infections, the common cold, sore throat, migraine, colic, stomach cramps, and toothaches and the promotion of wound healing. Based on...

  • Review
  • Open Access
1 Citations
10,586 Views
12 Pages

Recent Advances in Cochlear Implantation

  • Eric C. Shawkey,
  • J. Dixon Johns,
  • Armine Kocharyan,
  • Breanna Corle,
  • Emma Woolf,
  • Abbie Parks and
  • Selena E. Briggs

Since the inception of cochlear implantation, the field of technological advancements associated with cochlear implantation has continued to evolve, providing patients with sensorineural hearing loss access with greater sound appreciation capabilitie...

  • Article
  • Open Access
956 Views
13 Pages

Background Measurements and Simulations of the ComPair Balloon Flight

  • Zachary Metzler,
  • Nicholas Kirschner,
  • Lucas Smith,
  • Nicholas Cannady,
  • Makoto Sasaki,
  • Daniel Shy,
  • Regina Caputo,
  • Carolyn Kierans,
  • Aleksey Bolotnikov and
  • Anna Zajczyk
  • + 24 authors

ComPair, a prototype of the All-sky Medium Energy Gamma-ray Observatory (AMEGO), completed a short-duration high-altitude balloon campaign on 27 August 2023 from Fort Sumner, New Mexico, USA. The goal of the balloon flight was to demonstrate ComPair...

  • Feature Paper
  • Article
  • Open Access
14 Citations
6,654 Views
12 Pages

Morning Cortisol and Circulating Inflammatory Cytokine Levels: A Mendelian Randomisation Study

  • Skanda Rajasundaram,
  • Rezbieara P. Rahman,
  • Benjamin Woolf,
  • Sizheng Steven Zhao and
  • Dipender Gill

8 January 2022

Cortisol exerts a broad anti-inflammatory effect on the immune system. Inflammatory cytokines contribute to the molecular signalling pathways implicated in various autoimmune and inflammatory conditions. However, the mechanisms by which cortisol modu...

  • Communication
  • Open Access
42 Citations
10,896 Views
5 Pages

19 April 2022

We leveraged genetic variants associated with caffeine metabolism in the two-sample Mendelian randomization framework to investigate the effect of plasma caffeine levels on the risk of Alzheimer’s disease and Parkinson’s disease. Genetic...

  • Article
  • Open Access
3 Citations
4,301 Views
16 Pages

Characterization of a Centrifugal Microfluidic Orthogonal Flow Platform

  • Michael Shane Woolf,
  • Leah M. Dignan,
  • Scott M. Karas,
  • Hannah M. Lewis,
  • Kevyn C. Hadley,
  • Aeren Q. Nauman,
  • Marcellene A. Gates-Hollingsworth,
  • David P. AuCoin,
  • Heather R. Green and
  • James P. Landers
  • + 1 author

20 March 2022

To bring to bear the power of centrifugal microfluidics on vertical flow immunoassays, control of flow orthogonally through nanoporous membranes is essential. The on-disc approach described here leverages the rapid print-cut-laminate (PCL) disc fabri...

  • Article
  • Open Access
4 Citations
3,118 Views
22 Pages

Feasibility and Tolerability of Daily Microgreen Consumption in Healthy Middle-Aged/Older Adults: A Randomized, Open-Label, Controlled Crossover Trial

  • Sylvia Y. Lee,
  • Kiri A. Michell,
  • Michelle M. Butler,
  • Brayden T. Smith,
  • Emily K. Woolf,
  • Sydney C. Holmes,
  • Lauren E. Grabos,
  • Allegra R. Vazquez,
  • Hanan Isweiri and
  • Sarah A. Johnson
  • + 5 authors

28 January 2025

Background/Objectives: Microgreens are rich in nutrients and phytochemicals that can support healthy aging, including attenuation of cardiovascular disease risk. The nutrient and phytochemical contents of red beet (i.e., bull’s blood’ bee...

  • Article
  • Open Access
4 Citations
4,558 Views
15 Pages

10 July 2024

Women, particularly those in college, have the highest prevalence of any mental illness (MI), which negatively impacts social connection, academic performance, and health. Research into alternative treatment methods suggests that lifestyle behaviors...

  • Article
  • Open Access
1 Citations
1,546 Views
21 Pages

26 July 2025

The sorption process is most commonly described by Langmuir isotherms, which can be calculated from either a non-linear form or various linear forms. Despite the fact that the non-linear model is now preferred, articles using linear models continue t...

  • Article
  • Open Access
1 Citations
2,054 Views
11 Pages

We Continue Each Other

  • Sofie Gielis,
  • Eleanor Duffin and
  • Ingel Vaikla

31 October 2022

Three female voices with different cultural backgrounds and practices explore the concept and possibilities of the we-narrative. Starting from a position of critical reflection, we dive into the question of how to speak as a female WE. WE is used to...

  • Article
  • Open Access
2,116 Views
15 Pages

22 April 2024

Ford Madox Ford famously intended his First World War tetralogy Parade’s End to have “for its purpose the obviating of all future wars”. But why do we engage in war to begin with? Modernist literature provides some provocative expla...

  • Article
  • Open Access
2 Citations
7,122 Views
20 Pages

Factors Influencing Acceptance of Hippopotamus at a Large Reservoir in Nigeria

  • Lynne R. Baker,
  • Ibrahim A. Radda,
  • Vastinah N. Teneke,
  • Edward Kadala,
  • Rodney X. Sturdivant and
  • Gwaha A. Madwatte

27 October 2022

In a world increasingly affected by human presence and activities, achieving human–wildlife coexistence has become the goal of many wildlife conservation programs. Coexistence requires an understanding of factors that contribute to human tolera...

  • Article
  • Open Access
6 Citations
6,733 Views
18 Pages

Insoluble fiber (IF) recovered from the enzyme-assisted aqueous extraction process (EAEP) of soybeans is a fraction rich in carbohydrates and proteins. It can be used to enhance ethanol production in an integrated corn-soy biorefinery, which combines...