Next Article in Journal
Long-Term Outcomes of Adult Patients with Homocystinuria before and after Newborn Screening
Next Article in Special Issue
Dr. Louis Isaac Woolf: At the Forefront of Newborn Screening and the Diet to Treat Phenylketonuria—Biography to Mark His 100th Birthday
Previous Article in Journal
Neonatal Screening on Tandem Mass Spectrometry as a Powerful Tool for the Reassessment of the Prevalence of Underestimated Diseases in Newborns and Their Family Members: A Focus on Short Chain Acyl-CoA Dehydrogenase Deficiency
Previous Article in Special Issue
A Visit with Dr. Louis Woolf, Recognizing His 100th Birthday and His Contributions to the Diagnosis and Treatment of Phenylketonuria

The Early History of PKU

by 1 and 2,*
Department of Neurological Sciences, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
Canadian PKU and Allied Disorders, Toronto, ON M5A 1N1, Canada
Author to whom correspondence should be addressed.
Int. J. Neonatal Screen. 2020, 6(3), 59;
Received: 18 May 2020 / Revised: 24 July 2020 / Accepted: 27 July 2020 / Published: 29 July 2020
(This article belongs to the Special Issue History, Present and Future of Neonatal Screening)
The story of phenylketonuria (PKU) started in 1934 with Asbjørn Følling’s examination of two mentally retarded siblings from a Norwegian family. However, if their mother had not been so persistent in her search for somebody who could give her a reason why both her children were retarded, Asbjørn Følling’s name might never have been associated with PKU and surely the history of PKU would have started differently. In the short review below, the authors give a partly personal and therefore rare account of the early history of PKU, its treatment and the start of neonatal screening. Prof. Woolf is a pioneer of both the dietary treatment of PKU and neonatal screening; Mr. Adams is a long-time advocate for PKU patient interests. View Full-Text
Keywords: phenylketonuria; PKU; early treatment; screening phenylketonuria; PKU; early treatment; screening
Show Figures

Figure 1

MDPI and ACS Style

Woolf, L.I.; Adams, J. The Early History of PKU. Int. J. Neonatal Screen. 2020, 6, 59.

AMA Style

Woolf LI, Adams J. The Early History of PKU. International Journal of Neonatal Screening. 2020; 6(3):59.

Chicago/Turabian Style

Woolf, Louis I., and John Adams. 2020. "The Early History of PKU" International Journal of Neonatal Screening 6, no. 3: 59.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop