Forest resources are globally valuable and critical in many ecological processes. The forest canopy remote sensing model is an essential tool for understanding forest growth conditions. Over time, the model has evolved to consider the effects of the...
We applied a multi-method approach to reconstruct the Gorte rock avalanche (85–95 Mm3) located at the northeastern end of Lake Garda. The combination of field mapping, characterization of bedrock discontinuities, Dan3D-Flex runout modeling and dating...
Significant gaps exist in our knowledge of the impact of leaf aging on canopy signal variability, which limits our understanding of vegetation status based on remotely sensed data. To understand the effects of leaf aging at the leaf and canopy scales...
Inspired by a 1940s short story by Harry Bates, scripted by Edmund H. North, and directed by Robert Wise, The Day the Earth Stood Still (1951) is a science fiction cult classic. Of all its diverse interpretations, a commonly adopted reading influence...
Outside its native range, the invasive plant species giant goldenrod (Solidago gigantea) has been shown to increase belowground fungal biomass. This non-obvious effect is poorly characterized; we don’t know whether it is plant developmental stage-dep...
The transition in the use of fiber composite structures from special applications to application in the mass market is accompanied by high demands in quality assurance. The consequential costs of unclear process design, unknown fiber orientations, an...
Whole exome sequencing (WES) is a standard, relevant diagnostic strategy in medical genetics. However, commercial WES library preparation kits vary significantly in design and covered regions. Very few studies have assessed DNA tissue of origin&rsquo...
Background: Secondary cytoreductive surgery (SCS) followed by postoperative chemotherapy is a recognized option for select patients with platinum-sensitive first recurrent epithelial ovarian cancer (EOC), supported by the DESKTOP-III and SOC-1 trials...
The quantification of mitochondrial respiratory chain (MRC) enzymatic activities is essential for diagnosis of a wide range of mitochondrial diseases, ranging from inherited defects to secondary dysfunctions. MRC lesion is frequently linked to extend...
The objective of this study is to describe the alterations occurring during the neurodegenerative process in skin fibroblast cultures from C9orf72 patients. We characterized the oxidative stress, autophagy flux, small ubiquitin-related protein SUMO2/...
The association between Parkinson’s disease (PD) and mutations in genes involved in lysosomal and mitochondrial function has been previously reported. However, little is known about the involvement of other genes or cellular mechanisms. We aim...
Identification of low muscle mass becomes increasingly relevant due to its prognostic value in cancer patients. In clinical practice, mid-upper arm muscle circumference (MAMC) and bioelectrical impedance analysis (BIA) are often used to assess muscle...
A cure kinetics investigation of a high temperature-resistant phenol novolac cyanate ester toughened with polyether sulfone (CE-PES blend) was undertaken using non-isothermal differential scanning calorimetry. Thin ply carbon fiber prepreg, based on...
Classical homocystinuria (HCY) due to cystathionine beta-synthase (CBS) deficiency is included in many newborn screening programs, which traditionally use dried blood spot (DBS) methionine as the primary biomarker. However, some patients have normal...
The presence of pest rodents around food production and storage sites is one of many underlying problems contributing to food contamination and loss, particularly influencing food and nutrition security in low-income countries. By reducing both pre-...
Background: Leigh syndrome (LS) is a serious genetic disease that can be caused by mutations in dozens of different genes. Methods: Clinical study of a deafness pedigree in which some members developed LS. Cellular, biochemical and molecular genetic...
Mitochondrial diseases (MD) are a group of genetic and acquired disorders which present significant diagnostic challenges. Here we report the disease characteristics of a large cohort of pediatric MD patients (n = 95) with a definitive genetic diagno...
The combination of logging, burning, and livestock farming has been the main driver of European landscape sustainability for thousands of years. Whether or not livestock could keep these habitats on their own is under debate when extensive livestock...
CCDC186 protein is involved in the maturation of dense-core vesicles (DCVs) in the trans-Golgi network in neurons and endocrine cells. Mutations in genes involved in DCV regulation, other than CCDC186, have been described in patients with neurodevelo...
The objective of this study is to describe the stress relaxation behavior of an epoxy-based fiber-reinforced material. An existing incremental formulation of an orthotropic linear viscoelastic material behavior was adapted to Voigt notation and to th...
The objectives of this study were to experimentally determine the effects of the stress relaxation of a cyanate-ester-based composite, derive and integrate constitutive equations into commercial FEM software, and apply this approach to understand the...
When standard treatment options are not available anymore, patients with advanced cancer may participate in early phase clinical trials. Improving this complex decision-making process may improve their quality of life. Therefore, this prospective mul...
Objectives: The purpose of the study is to determine whether FOXL2 circulating tumor DNA can be used as a prognostic biomarker and marker for monitoring treatment response in patients with an adult-type granulosa cell tumor (aGCT). Methods: Plasma sa...
Efficient thawing can preserve the quality of frozen hairtail (Trichiurus lepturus) close to that of fresh hairtail. In contrast to air thawing (AT) and radio-frequency thawing (RT), this study looked at how graphene oxide (GO) and graphene magnetic...
The authors wish to make the following corrections to this paper [...]
Newborn screening (NBS) is a cornerstone of preventive medicine, enabling early diagnosis and treatment of severe congenital disorders. In Spain, despite the existence of a Basic Common Portfolio, the absence of a harmonized national panel has led to...