You are currently on the new version of our website. Access the old version .

58,761 Results Found

  • Article
  • Open Access
59 Citations
16,653 Views
22 Pages

Antioxidants in Sunscreens: Which and What For?

  • Ana Jesus,
  • Sandra Mota,
  • Ana Torres,
  • Maria T. Cruz,
  • Emília Sousa,
  • Isabel F. Almeida and
  • Honorina Cidade

6 January 2023

Ultraviolet (UV) radiation promotes the generation of reactive oxygen species (ROS) and nitrogen species (RNS), resulting in skin damage. Cosmetic industries have adopted a strategy to incorporate antioxidants in sunscreen formulations to prevent or...

  • Review
  • Open Access
341 Citations
22,653 Views
38 Pages

Carotenoids and Chlorophylls as Antioxidants

  • Antonio Pérez-Gálvez,
  • Isabel Viera and
  • María Roca

Chlorophylls and carotenoids are natural pigments that are present in our daily diet, especially with the increasing tendency towards more natural and healthy behaviors among consumers. As disturbed antioxidant homeostasis capacities seem to be impli...

  • Review
  • Open Access
347 Citations
29,819 Views
37 Pages

Antioxidants of Edible Mushrooms

  • Maja Kozarski,
  • Anita Klaus,
  • Dragica Jakovljevic,
  • Nina Todorovic,
  • Jovana Vunduk,
  • Predrag Petrović,
  • Miomir Niksic,
  • Miroslav M. Vrvic and
  • Leo Van Griensven

27 October 2015

Oxidative stress caused by an imbalanced metabolism and an excess of reactive oxygen species (ROS) lead to a range of health disorders in humans. Our endogenous antioxidant defense mechanisms and our dietary intake of antioxidants potentially regulat...

  • Review
  • Open Access
54 Citations
9,687 Views
21 Pages

Catalytic Antioxidants in the Kidney

  • Yu Ah Hong and
  • Cheol Whee Park

18 January 2021

Reactive oxygen species and reactive nitrogen species are highly implicated in kidney injuries that include acute kidney injury, chronic kidney disease, hypertensive nephropathy, and diabetic nephropathy. Therefore, antioxidant agents are promising t...

  • Review
  • Open Access
33 Citations
6,877 Views
17 Pages

Applications of Antioxidants in Dental Procedures

  • Fan Qi,
  • Haofei Huang,
  • Ming Wang,
  • Weifeng Rong and
  • Jing Wang

18 December 2022

As people are paying more and more attention to dental health, various dental treatment procedures have emerged, such as tooth bleaching, dental implants, and dental restorations. However, a large number of free radicals are typically produced during...

  • Review
  • Open Access
75 Citations
29,000 Views
35 Pages

Antioxidants and Sports Performance

  • Vicente Javier Clemente-Suárez,
  • Álvaro Bustamante-Sanchez,
  • Juan Mielgo-Ayuso,
  • Ismael Martínez-Guardado,
  • Alexandra Martín-Rodríguez and
  • José Francisco Tornero-Aguilera

18 May 2023

The role of reactive oxygen species and antioxidant response in training adaptations and sports performance has been a large issue investigated in the last few years. The present review aims to analyze the role of reactive oxygen species and antioxid...

  • Review
  • Open Access
86 Citations
13,138 Views
17 Pages

5 November 2013

Natural products with antioxidant properties have been extensively utilized in the pharmaceutical and food industry and have also been very popular as health-promoting herbal products. This review provides a summary of the literature published around...

  • Review
  • Open Access
165 Citations
25,586 Views
30 Pages

Oxidative Stress and Antioxidants—A Critical Review on In Vitro Antioxidant Assays

  • Raghavendhar R. Kotha,
  • Fakir Shahidullah Tareq,
  • Elif Yildiz and
  • Devanand L. Luthria

1 December 2022

Antioxidants have been widely studied in the fields of biology, medicine, food, and nutrition sciences. There has been extensive work on developing assays for foods and biological systems. The scientific communities have well-accepted the effectivene...

  • Review
  • Open Access
114 Citations
17,016 Views
47 Pages

Biochemistry of Antioxidants: Mechanisms and Pharmaceutical Applications

  • Sonia Losada-Barreiro,
  • Zerrin Sezgin-Bayindir,
  • Fátima Paiva-Martins and
  • Carlos Bravo-Díaz

25 November 2022

Natural antioxidants from fruits and vegetables, meats, eggs and fish protect cells from the damage caused by free radicals. They are widely used to reduce food loss and waste, minimizing lipid oxidation, as well as for their effects on health throug...

  • Perspective
  • Open Access
103 Citations
10,072 Views
12 Pages

Antioxidants, Food Processing and Health

  • Borut Poljsak,
  • Vito Kovač and
  • Irina Milisav

The loss and/or modification of natural antioxidants during various food processing techniques and storage methods, like heat/thermal, UV, pulsed electric field treatment, drying, blanching and irradiation is well described. Antioxidants in their red...

  • Review
  • Open Access
399 Citations
26,853 Views
29 Pages

Neuroprotective Effect of Antioxidants in the Brain

  • Kyung Hee Lee,
  • Myeounghoon Cha and
  • Bae Hwan Lee

28 September 2020

The brain is vulnerable to excessive oxidative insults because of its abundant lipid content, high energy requirements, and weak antioxidant capacity. Reactive oxygen species (ROS) increase susceptibility to neuronal damage and functional deficits, v...

  • Review
  • Open Access
5 Citations
5,900 Views
37 Pages

The Potential Application of Nanocarriers in Delivering Topical Antioxidants

  • Zulfan Zazuli,
  • Rika Hartati,
  • Cornelia Rosasepti Rowa,
  • Sukmadjaja Asyarie and
  • Satrialdi

6 January 2025

The imbalance in the production of reactive oxygen species (ROS) with endogenous antioxidant capacity leads to oxidative stress, which drives many disorders, especially in the skin. In such conditions, supplementing exogenous antioxidants may help th...

  • Article
  • Open Access
71 Citations
7,707 Views
20 Pages

Antioxidants Potential of the Filamentous Fungi (Mucor circinelloides)

  • Ahsan Hameed,
  • Syed Ammar Hussain,
  • Junhuan Yang,
  • Muhammad Umair Ijaz,
  • Qing Liu,
  • Hafiz Ansar Rasul Suleria and
  • Yuanda Song

7 October 2017

Three important strains of Mucor circinelloides grown in complete and minimal media for specified period (72 h, 120 h and 168 h) under submerged fermentation conditions were investigated for their potential antioxidants/secondary metabolite producti...

  • Review
  • Open Access
311 Citations
18,363 Views
24 Pages

Recent Developments in Effective Antioxidants: The Structure and Antioxidant Properties

  • Monika Parcheta,
  • Renata Świsłocka,
  • Sylwia Orzechowska,
  • Monika Akimowicz,
  • Renata Choińska and
  • Włodzimierz Lewandowski

15 April 2021

Since the last few years, the growing interest in the use of natural and synthetic antioxidants as functional food ingredients and dietary supplements, is observed. The imbalance between the number of antioxidants and free radicals is the cause of ox...

  • Article
  • Open Access
5 Citations
5,015 Views
15 Pages

Deposition Efficacy of Natural and Synthetic Antioxidants on Fabrics

  • Paola Giannì,
  • Heiko Lange,
  • Giulia Bianchetti,
  • Conny Joos,
  • David W. Brogden and
  • Claudia Crestini

7 September 2020

Pine bark extracts were tested as valid natural alternatives to common phenolic antioxidants to be deposited onto solid matrices. An analytical method for determining both deposition-efficacy and maintenance of antioxidant activity on fabrics surface...

  • Review
  • Open Access
31 Citations
10,027 Views
7 Pages

23 December 2011

Since evidence became available that free radicals were involved in mechanisms for the development of major diseases, including cardiovascular disease and cancer, there has been considerable research into the properties of natural dietary antioxidant...

  • Review
  • Open Access
52 Citations
15,963 Views
17 Pages

The Use of Antioxidants in the Treatment of Migraine

  • Marta Goschorska,
  • Izabela Gutowska,
  • Irena Baranowska-Bosiacka,
  • Katarzyna Barczak and
  • Dariusz Chlubek

28 January 2020

Despite numerous studies concerning the pathophysiology of migraine, the exact molecular mechanism of disturbances underlying migraine is still unknown. Furthermore, oxidative stress is considered to play a significant role in migraine pathogenesis....

  • Review
  • Open Access
60 Citations
14,912 Views
13 Pages

Nanocarriers for Delivery of Antioxidants on the Skin

  • María Pilar Vinardell and
  • Montserrat Mitjans

10 October 2015

Skin is protected from the harmful effects of free radicals by the presence of an endogenous antioxidant system. However, when exposed to ultraviolet (UV) radiation, there is an imbalance between pro-oxidants and antioxidants, leading to oxidative st...

  • Feature Paper
  • Review
  • Open Access
32 Citations
6,867 Views
9 Pages

17 February 2016

Cardiovascular disease (CVD), the world’s primary cause of death and disability, represents a global health problem and involves a great public financial commitment in terms of both inability to work and pharmaceutical costs. CVD is characterized by...

  • Review
  • Open Access
49 Citations
8,250 Views
23 Pages

Benefits of Natural Antioxidants on Oral Health

  • Giuseppina Malcangi,
  • Assunta Patano,
  • Anna Maria Ciocia,
  • Anna Netti,
  • Fabio Viapiano,
  • Irene Palumbo,
  • Irma Trilli,
  • Mariafrancesca Guglielmo,
  • Alessio Danilo Inchingolo and
  • Gianna Dipalma
  • + 3 authors

In recent years, special attention has been paid to the correlation between oxidation–reduction mechanisms and human health. The free radicals produced via physiological cellular biochemical processes are major contributors to oxidation phenome...

  • Project Report
  • Open Access
63 Citations
8,558 Views
8 Pages

Antioxidants: Terminology, Methods, and Future Considerations

  • Khiena Brainina,
  • Natalia Stozhko and
  • Marina Vidrevich

Unreliable terminology and incompatible units of antioxidant activity/concentration expression lead to the failure of antioxidant clinical trials, ambiguity of conclusions about the effect of a chosen therapy in medicine and evaluation of food qualit...

  • Review
  • Open Access
171 Citations
13,792 Views
21 Pages

Reaction Dynamics of Flavonoids and Carotenoids as Antioxidants

  • Rui-Min Han,
  • Jian-Ping Zhang and
  • Leif H. Skibsted

21 February 2012

Flavonoids and carotenoids with rich structural diversity are ubiquitously present in the plant kingdom. Flavonoids, and especially their glycosides, are more hydrophilic than most carotenoids. The interaction of flavonoids with carotenoids occurs ac...

  • Review
  • Open Access
49 Citations
8,816 Views
16 Pages

Glaucoma and Antioxidants: Review and Update

  • Jose Javier Garcia-Medina,
  • Elena Rubio-Velazquez,
  • Maria Dolores Lopez-Bernal,
  • Alejandro Cobo-Martinez,
  • Vicente Zanon-Moreno,
  • Maria Dolores Pinazo-Duran and
  • Monica del-Rio-Vellosillo

22 October 2020

Glaucoma is a neurodegenerative disease characterised by the progressive degeneration of retinal ganglion cells. Oxidative stress has been related to the cell death in this disease. Theoretically, this deleterious consequence can be reduced by antiox...

  • Review
  • Open Access
237 Citations
18,922 Views
26 Pages

Natural Antioxidants: Fascinating or Mythical Biomolecules?

  • Ashwell R. Ndhlala,
  • Mack Moyo and
  • Johannes Van Staden

8 October 2010

Research on the use, properties, characteristics and sources of antioxidants especially phenolic compounds, flavonoids, vitamins, synthetic chemicals and some micronutrients began in the late 18th century. Since then antioxidant research has received...

  • Review
  • Open Access
187 Citations
17,578 Views
11 Pages

Antioxidants: Positive or Negative Actors?

  • Bahare Salehi,
  • Miquel Martorell,
  • Jack L. Arbiser,
  • Antoni Sureda,
  • Natália Martins,
  • Pawan Kumar Maurya,
  • Mehdi Sharifi-Rad,
  • Pradeep Kumar and
  • Javad Sharifi-Rad

25 October 2018

The term “antioxidant” is one of the most confusing definitions in biological/medical sciences. In chemistry, “antioxidant” is simply conceived “a compound that removes reactive species, mainly those oxygen-derived”, while in a cell context, the conc...

  • Review
  • Open Access
4 Citations
3,918 Views
23 Pages

Printing-Based Assay and Therapy of Antioxidants

  • Sera Hong,
  • Baskaran Purushothaman and
  • Joon Myong Song

28 October 2020

Antioxidants are essential in regulating various physiological functions and oxidative deterioration. Over the past decades, many researchers have paid attention to antioxidants and studied the screening of antioxidants from natural products and thei...

  • Review
  • Open Access
115 Citations
11,354 Views
26 Pages

Nitroxides as Antioxidants and Anticancer Drugs

  • Marcin Lewandowski and
  • Krzysztof Gwozdzinski

22 November 2017

Nitroxides are stable free radicals that contain a nitroxyl group with an unpaired electron. In this paper, we present the properties and application of nitroxides as antioxidants and anticancer drugs. The mostly used nitroxides in biology and medici...

  • Review
  • Open Access
185 Citations
14,503 Views
30 Pages

Plant-Derived Natural Antioxidants in Meat and Meat Products

  • Georgios Manessis,
  • Aphrodite I. Kalogianni,
  • Thomai Lazou,
  • Marios Moschovas,
  • Ioannis Bossis and
  • Athanasios I. Gelasakis

2 December 2020

The global meat industry is constantly evolving due to changes in consumer preferences, concerns and lifestyles, as well as monetary, geographical, political, cultural and religious factors. Part of this evolution is the introduction of synthetic ant...

  • Article
  • Open Access
6 Citations
3,042 Views
16 Pages

Evaluation of Antioxidant Properties and Molecular Design of Lubricant Antioxidants Based on QSPR Model

  • Jianfang Liu,
  • Yaoyun Zhang,
  • Chenglingzi Yi,
  • Rongrong Zhang,
  • Sicheng Yang,
  • Ting Liu,
  • Dan Jia,
  • Qing Yang and
  • Shuai Peng

Two quantitative structure–property relationship (QSPR) models of hindered phenolic antioxidants in lubricating oils were established to help guide the molecular structure design of antioxidants. Firstly, stepwise regression (SWR) was used to f...

  • Review
  • Open Access
17 Citations
5,067 Views
25 Pages

Food Antioxidants and Their Interaction with Human Proteins

  • Olgica Nedić,
  • Ana Penezić,
  • Simeon Minić,
  • Mirjana Radomirović,
  • Milan Nikolić,
  • Tanja Ćirković Veličković and
  • Nikola Gligorijević

Common to all biological systems and living organisms are molecular interactions, which may lead to specific physiological events. Most often, a cascade of events occurs, establishing an equilibrium between possibly competing and/or synergistic proce...

  • Review
  • Open Access
18 Citations
4,993 Views
27 Pages

Nutrigenomics of Natural Antioxidants in Broilers

  • Ioanna Kouvedaki,
  • Athanasios C. Pappas,
  • Peter F. Surai and
  • Evangelos Zoidis

22 February 2024

The broiler industry supplies high-quality animal protein to the world. The ban of antibiotics as growth promoters has opened the way for plenty of phytochemicals and antioxidants to be explored. This study summarizes the use of natural antioxidants...

  • Review
  • Open Access
57 Citations
18,979 Views
19 Pages

The Importance of Natural Antioxidants in Female Reproduction

  • Janka Vašková,
  • Zuzana Klepcová,
  • Ivana Špaková,
  • Peter Urdzík,
  • Jana Štofilová,
  • Izabela Bertková,
  • Marek Kľoc and
  • Miroslava Rabajdová

Oxidative stress (OS) has an important role in female reproduction, whether it is ovulation, endometrium decidualization, menstruation, oocyte fertilization, or development andimplantation of an embryo in the uterus. The menstrual cycle is regulated...

  • Review
  • Open Access
21 Citations
5,772 Views
18 Pages

The definition of antioxidants (AOs), their classification and properties as well as electrochemical sensor systems for AOs analysis are briefly discussed. The analytical capabilities of coulometric titration with electrogenerated titrants as sensor...

  • Review
  • Open Access
22 Citations
5,321 Views
19 Pages

Biosensors for Antioxidants Detection: Trends and Perspectives

  • Melinda David,
  • Monica Florescu and
  • Camelia Bala

1 September 2020

Herein we review the recent advances in biosensors for antioxidants detection underlying principles particularly emphasizing advantages along with limitations regarding the ability to discriminate between the specific antioxidant or total content. Re...

  • Review
  • Open Access
61 Citations
9,925 Views
26 Pages

Role of Antioxidants in Alleviating Bisphenol A Toxicity

  • Shehreen Amjad,
  • Md Saidur Rahman and
  • Myung-Geol Pang

25 July 2020

Bisphenol A (BPA) is an oestrogenic endocrine disruptor widely used in the production of certain plastics, e.g., polycarbonate, hard and clear plastics, and epoxy resins that act as protective coating for food and beverage cans. Human exposure to thi...

  • Review
  • Open Access
277 Citations
32,189 Views
13 Pages

Cherry Antioxidants: From Farm to Table

  • Gianna Ferretti,
  • Tiziana Bacchetti,
  • Alberto Belleggia and
  • Davide Neri

12 October 2010

The dietary consumption of fruits and vegetables is associated with a lower incidence of degenerative diseases such as cardiovascular disease and certain types of cancers. Most recent interest has focused on the bioactive phenolic compounds found in...

  • Review
  • Open Access
78 Citations
13,787 Views
19 Pages

Apiaceae as an Important Source of Antioxidants and Their Applications

  • Punniamoorthy Thiviya,
  • Ashoka Gamage,
  • Dinushika Piumali,
  • Othmane Merah and
  • Terrence Madhujith

22 November 2021

The excess level of reactive oxygen species (ROS) disturbs the oxidative balance leading to oxidative stress, which, in turn, causes diabetes mellites, cancer, and cardiovascular diseases. These effects of ROS and oxidative stress can be balanced by...

  • Review
  • Open Access
236 Citations
12,928 Views
19 Pages

Antioxidants and Atherosclerosis: Mechanistic Aspects

  • Khojasteh Malekmohammad,
  • Robert D. E. Sewell and
  • Mahmoud Rafieian-Kopaei

Atherosclerosis is a chronic inflammatory disease which is a major cause of coronary heart disease and stroke in humans. It is characterized by intimal plaques and cholesterol accumulation in arterial walls. The side effects of currently prescribed s...

  • Systematic Review
  • Open Access
17 Citations
2,612 Views
9 Pages

The Potential Role of Antioxidants in the Treatment of Peripheral Arterial Disease: A Systematic Review

  • Shayan Keramat,
  • Hiva Sharebiani,
  • Malay Patel,
  • Bahare Fazeli and
  • Agata Stanek

28 October 2022

Peripheral arterial disease (PAD) has a worldwide prevalence and is a significant cause of cardiovascular morbidity and mortality. Due to its high prevalence and higher rates of ischemic cardiovascular and lower-extremity events, its treatment is ess...

of 1,176