You are currently on the new version of our website. Access the old version .

Most Cited

  • Review
  • Open Access
206 Citations
28,584 Views
20 Pages

Interleukins (ILs) are signaling molecules that are crucial in regulating immune responses during infectious diseases. Pro-inflammatory ILs contribute to the activation and recruitment of immune cells, whereas anti-inflammatory ILs help to suppress e...

  • Systematic Review
  • Open Access
53 Citations
10,572 Views
17 Pages

Epidemiology and Economic Burden of Chikungunya: A Systematic Literature Review

  • Lourrany Borges Costa,
  • Francisca Kalline de Almeida Barreto,
  • Marina Carvalho Arruda Barreto,
  • Thyago Henrique Pereira dos Santos,
  • Maria de Margarette Oliveira de Andrade,
  • Luís Arthur Brasil Gadelha Farias,
  • André Ricardo Ribas de Freitas,
  • Miguel Julian Martinez and
  • Luciano Pamplona de Góes Cavalcanti

Chikungunya (CHIK) is a re-emerging viral infection endemic in tropical and subtropical areas. While the typical clinical presentation is an acute febrile syndrome, long-term articular complications and even death can occur. This review characterizes...

  • Review
  • Open Access
48 Citations
145,428 Views
16 Pages

In the past decade, the Philippines has gained notoriety as the country with the fastest-growing human immunodeficiency virus (HIV) epidemic in the Western Pacific region. While the overall trends of HIV incidence and acquired immunodeficiency syndro...

  • Systematic Review
  • Open Access
44 Citations
7,319 Views
23 Pages

As the COVID-19 pandemic continues and transitions to an endemic stage, booster vaccines will play an important role in personal and public health. However, convincing people to take boosters continues to be a key obstacle. This study systematically...

  • Review
  • Open Access
42 Citations
8,510 Views
13 Pages

Molecular Docking and Molecular Dynamics Simulations in Related to Leishmania donovani: An Update and Literature Review

  • Mabel R. Challapa-Mamani,
  • Eduardo Tomás-Alvarado,
  • Angela Espinoza-Baigorria,
  • Darwin A. León-Figueroa,
  • Ranjit Sah,
  • Alfonso J. Rodriguez-Morales and
  • Joshuan J. Barboza

Leishmaniasis, a disease caused by Leishmania parasites and transmitted via sandflies, presents in two main forms: cutaneous and visceral, the latter being more severe. With 0.7 to 1 million new cases each year, primarily in Brazil, diagnosing remain...

  • Review
  • Open Access
41 Citations
9,589 Views
22 Pages

Leishmaniasis: Immune Cells Crosstalk in Macrophage Polarization

  • Fernanda Silva Almeida,
  • Shayenne Eduarda Ramos Vanderley,
  • Fernando Cézar Comberlang,
  • Arthur Gomes de Andrade,
  • Luiz Henrique Agra Cavalcante-Silva,
  • Edson dos Santos Silva,
  • Pedro Henrique de Sousa Palmeira,
  • Ian P. G. do Amaral and
  • Tatjana S. L. Keesen

Leishmaniasis is a complex infectious parasitic disease caused by protozoa of the genus Leishmania, belonging to a group of neglected tropical diseases. It establishes significant global health challenges, particularly in socio-economically disadvant...

  • Perspective
  • Open Access
41 Citations
14,020 Views
18 Pages

Leishmaniasis is classified as a neglected tropical disease (NTD), caused by protozoan parasites of the genus Leishmania, which are transmitted to humans and other animals through the bite of infected female phlebotomine sandflies. There are three fo...

  • Review
  • Open Access
35 Citations
7,369 Views
19 Pages

Cystic Echinococcosis in the Early 2020s: A Review

  • Mihai-Octav Hogea,
  • Bogdan-Florin Ciomaga,
  • Mădălina-Maria Muntean,
  • Andrei-Alexandru Muntean,
  • Mircea Ioan Popa and
  • Gabriela Loredana Popa

Cystic echinococcosis (CE) is a zoonosis caused by metacestodes, the larval stage of Echinococcus granulosus. Although the World Health Organization (WHO) has defined CE as a neglected disease, it is the second most important foodborne parasitic...

  • Review
  • Open Access
35 Citations
23,130 Views
21 Pages

Dengue as a Disease Threatening Global Health: A Narrative Review Focusing on Latin America and Brazil

  • Carlos Letacio Silveira Lessa,
  • Katharine Valéria Saraiva Hodel,
  • Marilda de Souza Gonçalves and
  • Bruna Aparecida Souza Machado

Arboviruses constitute the largest known group of viruses. These viruses are the etiological agents of pathologies known as arboviruses, with dengue being one of the most prevalent. Dengue has resulted in important socioeconomic burdens placed on dif...

  • Review
  • Open Access
31 Citations
6,372 Views
14 Pages

Chagas Disease in Europe

  • Marta Gonzalez-Sanz,
  • Clara Crespillo-Andújar,
  • Sandra Chamorro-Tojeiro,
  • Begoña Monge-Maillo,
  • Jose A. Perez-Molina and
  • Francesca F. Norman

Chagas disease is currently present in many non-endemic countries and remains a neglected tropical disease globally. A review of the literature identified significant gaps and scarcity of updated information from European countries, with most studies...

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Trop. Med. Infect. Dis. - ISSN 2414-6366