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Tropical Medicine and Infectious Disease, Volume 11, Issue 6

2026 June - 28 articles

Cover Story: Schistosomiasis remains a major parasitic disease and an important cause of chronic morbidity in endemic regions. South Africa is endemic for schistosomiasis and is expanding control measures, including mass drug administration. To address the lack of current prevalence data, this study retrospectively analysed public-sector laboratory-confirmed cases from 2019 to 2024. A total of 73,680 cases were diagnosed in urine and stool, with Schistosoma haematobium accounting for 99.9% of infections. The burden was concentrated among boys aged 5–19 years and in KwaZulu-Natal, Limpopo, and Mpumalanga Provinces. These findings provide evidence to support targeted interventions and strengthen national schistosomiasis control programmes. View this paper
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Articles (28)

  • Article
  • Open Access
1,689 Views
11 Pages

Molecular Identification of Schistosoma Species Associated with Atypical Urinary Eggs in Abuja (Nigeria): Evidence of Potential Zoonotic Transmission

  • Solomon Monday Jacob,
  • Sophie Y. Akinbo,
  • Oluwaremilekun G. Ajakaye,
  • Uwem F. Ekpo,
  • Zainab Omoruyi,
  • Temitope Agbana,
  • Louise Makau-Barasa,
  • Moses O. Aderogba,
  • Jan-Carel Diehl and
  • Frederick O. Akinbo
  • + 4 authors

Schistosomiasis remains a major public health concern in Nigeria. We molecularly characterized Schistosoma eggs obtained from human urine to identify species and assess the presence of hybrid schistosomes in Abuja, Nigeria. Urine samples were collect...

(This article belongs to the Special Issue Advances in Parasitic Neglected Tropical Diseases—2nd Edition)
  • Article
  • Open Access
539 Views
14 Pages

Imported Tungiasis in Greece: Secondary Household Transmission and Transient Mixed Liver Enzyme Elevation

  • Thomas Fotas,
  • Ioannis A. Giantsis,
  • Menelaos Lefkaditis,
  • Ioannis S. Pappas,
  • Mathis A. B. Christodoulopoulos,
  • Efterpi Zafiriou,
  • Electra Nicolaidou,
  • Alexander C. Katoulis and
  • Georgios Christodoulopoulos

Tungiasis is a cutaneous ectoparasitosis caused by the penetration of gravid female Tunga penetrans fleas into the epidermis. Although endemic in tropical and subtropical regions, it remains rare in Europe, where most cases are travel-associated and...

(This article belongs to the Section Neglected and Emerging Tropical Diseases)
  • Article
  • Open Access
1,155 Views
10 Pages

Implementation of Open PCR System for the Detection of TB/DR-TB and NTM in Sputum Samples from Suspected Pulmonary Tuberculosis Patients in Medan, Indonesia

  • R Lia Kusumawati,
  • Mirzan Hasibuan,
  • Nisrina Tari,
  • Gema Nazri Yanni,
  • Laura Isa Ginting,
  • Cynthia Gozali and
  • Tryna Tania

(1) Background: Indonesia faces the dual challenge of a high tuberculosis (TB) burden and increasing drug resistance. Conventional molecular diagnostics frequently fail to detect isoniazid resistance and nontuberculous mycobacteria (NTM). This study...

(This article belongs to the Special Issue Tuberculosis Diagnosis: Current, Ongoing and Future Approaches)
  • Article
  • Open Access
940 Views
17 Pages

Anti-Dengue IgG Seroprevalence and Exposure-Related Risk in Italian Military Personnel Deployed on Overseas Missions: A Cross-Sectional Study

  • Andrea Ciammaruconi,
  • Anna Rocchetti,
  • Filippo Molinari,
  • Elisa Recchia,
  • Nathalie Totaro,
  • Chiara Pascolini,
  • Silvia Chimienti,
  • Giovanni Faggioni,
  • Riccardo De Santis and
  • Florigio Lista
  • + 2 authors

Dengue virus infection remains a significant public health challenge in endemic regions, with growing evidence of autochthonous transmission in Europe. Assessing serological exposure in high-risk populations such as military personnel deployed to end...

(This article belongs to the Section Neglected and Emerging Tropical Diseases)
  • Article
  • Open Access
1,262 Views
16 Pages

Borrelia miyamotoi in Saint Petersburg and Leningrad Oblast, Russia: A Multi-Level Assessment of Ticks, Rodents, and Human Exposure

  • Ivan Lyzenko,
  • Olga Stukolova,
  • Nikolay Tokarevich,
  • Marina Sokolova,
  • Regina Baimova,
  • Islam Karmokov,
  • Ekaterina Riabiko,
  • Daria Grechishkina,
  • Gelena Lunina and
  • Vladimir Dedkov

Background: Borrelia miyamotoi is an emerging tick-borne pathogen causing relapsing fever in humans. Although Saint Petersburg and the surrounding Leningrad Oblast harbor a high abundance of ixodid ticks (I. ricinus, I. persulcatus), no integrat...

(This article belongs to the Special Issue Emerging Vector-Borne Diseases and Public Health Challenges)
  • Article
  • Open Access
1 Citations
1,703 Views
18 Pages

Determinants of Rabies Post-Exposure Prophylaxis Compliance in Bangladesh: Informing Policy for Elimination by 2030

  • Sumon Ghosh,
  • Mohammad Nayeem Hasan,
  • Sukanta Chowdhury,
  • Narayan C. Paul,
  • Waqas Ahmad,
  • Jiangang Chen and
  • Thankam S. Sunil

Rabies remains a preventable yet fatal zoonotic disease and a major public health concern in Bangladesh, which aims to eliminate dog-mediated human rabies by 2030. Despite free availability of post-exposure prophylaxis (PEP), adherence to the WHO-rec...

(This article belongs to the Special Issue Recent Advances in Rabies Surveillance and Control)
  • Article
  • Open Access
806 Views
10 Pages

Rickettsia parkeri as a Probable Agent of Mild Spotted-Fever Group Rickettsiosis Identified by Seroreactivity in Villeta, Colombia

  • Carlos Ramiro Silva-Ramos,
  • Peter C. Melby,
  • Patricia V. Aguilar,
  • Miguel M. Cabada,
  • Juan David Rodas,
  • Marylin Hidalgo and
  • Álvaro A. Faccini-Martínez

Spotted fever group (SFG) rickettsioses are emerging zoonotic diseases of increasing relevance in Latin America, yet the specific species involved in human infections remain poorly defined in many endemic regions. This study aimed to determine the mo...

(This article belongs to the Special Issue Latin American Tropical Diseases: Epidemiology & Prevention)
  • Article
  • Open Access
845 Views
13 Pages

Serological, Molecular, and Epidemiological Investigation of Toxoplasma gondii Infection in Blood Donors from the Brazilian Semiarid Region

  • Basílio Felizardo Lima Neto,
  • Ana Caroline Dantas Amorim,
  • Maria Jessianny Diniz Alves,
  • Ana Maria Santos Lima,
  • Janielton Albuquerque Lima,
  • Celine Sousa Menezes Sá,
  • Emilly Henrique Silva,
  • João Luís Garcia,
  • Vinicius Longo Ribeiro Vilela and
  • Thais Ferreira Feitosa

This study aimed to determine the prevalence and risk factors associated with Toxoplasma gondii infection in blood donors from the Brazilian Semiarid region, and to explore its implications for transfusion safety. Samples were collected from 646 dono...

(This article belongs to the Special Issue Toxoplasma and Neospora: Public Health Challenges in Tropical Regions)
  • Article
  • Open Access
908 Views
16 Pages

Detection of Dengue Virus and Serological Evidence of Chikungunya and Zika Virus Exposure in Patients with Acute Febrile Syndrome in Córdoba, Colombia

  • Paula A. Avilés-Vergara,
  • Dina Ricardo-Caldera,
  • Carlos Alberto Bolívar Pineda,
  • Eliud Daniel Pérez Vergara,
  • Ana Carolina Negrette Oquendo,
  • Luis Carlos Ruiz Garces,
  • Sara Cecilia Soto-De León and
  • Catalina Tovar-Acero

Background/Objectives: Arboviral diseases transmitted by Aedes mosquitoes, including Dengue (DENV), Zika (ZIKV), and Chikungunya (CHIKV), represent a major public health challenge in tropical regions. Their clinical similarity complicates differentia...

(This article belongs to the Section Vector-Borne Diseases)
  • Review
  • Open Access
1,707 Views
24 Pages

Crimean–Congo Hemorrhagic Fever Virus in Africa: Epidemiological Trends, Transmission Ecology, Hotspot Heterogeneity, and Preparedness Challenges—A Narrative Review

  • Elichilia Robert Shao,
  • Jeremia J. Pyuza,
  • Tito Kibona,
  • Laura Shirima,
  • Eliaichi A. Mlay,
  • Alice Andongolile,
  • Ray Kayaga,
  • Semvua Kilonzo,
  • Blandina T. Mmbaga and
  • Jaffu Chilongola

Background: Crimean–Congo hemorrhagic fever virus (CCHFV) is an important tick-borne zoonosis and an emerging public health threat across Africa. Although evidence of viral circulation is mounting, information remains fragmented, limiting a com...

(This article belongs to the Topic Vector-Borne Disease Spatial Epidemiology, Disease Ecology, and Zoonoses)
  • Systematic Review
  • Open Access
877 Views
12 Pages

Background/Objectives: Rifampicin-resistant tuberculosis (RR-TB) and HIV co-infection remain major contributors to morbidity and mortality, particularly in high-burden settings. HIV-related clinical factors, including viral suppression, CD4-defined i...

(This article belongs to the Special Issue HIV Testing, Prevention and Care Interventions, 2nd Edition)
  • Brief Report
  • Open Access
816 Views
9 Pages

Post-Deployment Screening of Thailand Military Units Deployed to South Sudan from 2023 to 2025 Reveals High Rates of Sub-Microscopic P. falciparum Malaria

  • Min Kramyoo,
  • Sidhartha Chaudhury,
  • Watcharee Yokanit,
  • Kamonwan Siriwattanakul,
  • Porruthai Kittikanara,
  • Brian A. Vesely,
  • Darunee Utennam,
  • Nakarin Sansanayudh and
  • Sutchana Tabprasit

Peacekeeping operations in sub-Saharan Africa continue to be impacted by malaria both in-country and among returning service members. The Royal Thai Army (RTA) deploys an engineering company to Juba and Rumbek, South Sudan to conduct peacekeeping ope...

(This article belongs to the Special Issue Military Medicine: An Everlasting War against Tropical and Infectious Diseases)
  • Article
  • Open Access
771 Views
18 Pages

Reduced HAV IgG Seropositivity Among Unvaccinated People Living with HIV: The Weak Shield

  • Huan Xu,
  • Sheng Huang,
  • Haotian Huang,
  • Xinrui Gao,
  • Chunlin Chen,
  • Guangyu Liang,
  • Aili Lu,
  • Xuwen Xu,
  • Yuyuan Xu and
  • Shaohang Cai
  • + 2 authors

People living with HIV (PLWH) represent a high-risk population for hepatitis A virus (HAV) infection, with exposure risk equal to or higher than that of the general population, particularly within adult risk networks. Anti-HAV immunoglobulin G (IgG)...

(This article belongs to the Special Issue HIV Elimination: Addressing Challenges in Vulnerable Populations and Reducing Discrimination)
  • Article
  • Open Access
830 Views
17 Pages

Rapid and Sensitive Detection of Schistosoma mansoni in the Intermediate Snail Hosts Using Loop-Mediated Isothermal Amplification (LAMP) Diagnostics

  • Hong-Mei Li,
  • Zhi-Qiang Qin,
  • Shan Lv,
  • Jing Xu,
  • Nicholas Midzi,
  • Masceline Jenipher Mutsaka-Makuvaza,
  • Ting Feng,
  • Robert Bergquist and
  • Xiao-Nong Zhou

Schistosomiasis is an important snail-borne neglected tropical disease, and detecting infected snails is a priority for its control and elimination. However, conventional parasitological methods, such as crushed snails and cercarial shedding, have li...

(This article belongs to the Section Neglected and Emerging Tropical Diseases)
  • Article
  • Open Access
748 Views
15 Pages

Factors Associated with Virological Non-Suppression Among People Living with HIV Receiving Antiretroviral Therapy in Kazakhstan: A National Registry-Based Study

  • Anel Ibrayeva,
  • Zhamilya Nugmanova,
  • Anarkhan Nurkerimova,
  • Aigerim Alimbekova,
  • Marat Tukeyev,
  • Alfiya Denebaeva,
  • Jack DeHovitz,
  • Yerlan Ismoldayev,
  • Bolat Sadykov and
  • Ildar Fakhradiyev
  • + 1 author

Background: Virological suppression is a key outcome of antiretroviral therapy. Despite progress in HIV treatment in Kazakhstan, virological non-suppression remains a relevant clinical and public health issue requiring further analysis. This study ai...

(This article belongs to the Special Issue HIV Elimination: Addressing Challenges in Vulnerable Populations and Reducing Discrimination)
  • Case Report
  • Open Access
1,056 Views
8 Pages

Cutaneous Larva Migrans Acquired in a Tropical Area of Ecuador: Diagnostic Delay, Clinical Evolution, and Recognition Challenges

  • Verónica Salomé Sánchez-Peralta,
  • Katherine Lizeth Moposa-Balarezo,
  • Fabio Marcelo Idrovo-Espín and
  • Rommy Terán

Cutaneous Larva Migrans (CLM) is a neglected tropical disease (NTD) caused by zoonotic Ancylostomatidae larvae, mainly Ancylostoma braziliense and Ancylostoma caninum, which infect dogs and cats. Humans are accidental hosts, acquiring infection when...

(This article belongs to the Section Neglected and Emerging Tropical Diseases)
  • Article
  • Open Access
1,203 Views
16 Pages

Persistent Burden of Schistosomiasis in South Africa: A National Laboratory-Based Analysis, 2019–2024

  • Charlotte Sriruttan-Nel,
  • Bhavani Moodley,
  • John Frean,
  • Dumisani Mlotshwa and
  • Veerle Msimang

Schistosomiasis remains the second leading cause of death among parasitic diseases globally, contributing substantially to chronic morbidity and disability. South Africa (SA) is endemic for schistosomiasis, with ongoing efforts to expand mass drug ad...

(This article belongs to the Special Issue Advances in the Control and Elimination of Parasitic Neglected Tropical Diseases)
  • Review
  • Open Access
2 Citations
1,697 Views
33 Pages

Reducing Antibiotic Dependence in Poultry: The Potential of Phytochemicals as Antibiotic Alternatives Against Bacterial Foodborne Pathogens

  • Rithu Chandran,
  • Thomas Denagamage,
  • Daniel M. Czyz,
  • Subhashinie Kariyawasam and
  • Abraham Joseph Pellissery

Antimicrobial resistance (AMR) is one of the most serious threats to global public health, driven in part by extensive antibiotic use in food-producing animals. The poultry industry, a major contributor to the global animal protein supply, has depend...

(This article belongs to the Special Issue Zoonotic Pathogens and Antimicrobial Resistance)
  • Article
  • Open Access
1,067 Views
14 Pages

Mucormycosis is a rare, invasive fungal infection associated with high mortality. This retrospective study evaluated adult mucormycosis cases followed in our clinic between 2015 and 2025. A total of 13 patients were included, with a mean age of 50.92...

(This article belongs to the Special Issue Mucormycosis Unmasked: Advances in Pathogenesis and Emerging Therapeutic Frontiers)
  • Article
  • Open Access
1 Citations
956 Views
17 Pages

Malaria reduction in the Americas has slowed despite sustained elimination efforts, suggesting important changes in the spatial organization of residual transmission. This study evaluated whether declining Plasmodium falciparum incidence between 2000...

(This article belongs to the Special Issue One Health Approach to Malaria Elimination)
  • Article
  • Open Access
699 Views
15 Pages

Serological Susceptibility to Measles Among International Students in South Korea After a Cluster of Cases: A Cross-Sectional Study

  • Minyu Qin,
  • Na Young Hong,
  • Shin Woo Kim,
  • Ji Hyuk Park,
  • Seok Ju Yoo,
  • Sung Jun Park,
  • Younjoo Kim,
  • Sang Yun Cho,
  • Sook Hee Park and
  • Kwan Lee
  • + 10 authors

Background: Even though South Korea had eliminated measles in 2006, a localized cluster of measles occurred in a university dormitory in Gyeongsangbuk-do, South Korea, in 2024, involving 22 international students. This study aims to explore measles t...

(This article belongs to the Section Infectious Diseases)
  • Article
  • Open Access
1 Citations
1,008 Views
22 Pages

Knowledge, Attitudes, Practices, and Information Pathways Related to Brucellosis Among Adults in Najran City, Saudi Arabia: A Stratified Time–Location Cross-Sectional Study

  • Abdullateef Abdullah Alshehri,
  • Mohammad Y. Alqahtani,
  • Osman AE. Elnoubi,
  • Mohsen A. Qahtani,
  • Dehiyyan E. Alyami,
  • Meshal M. Alabbas,
  • Mosa M. Bahnass,
  • Abdullah Alshehari,
  • Mohammed A. Alshehri and
  • Mohammed A. Alshahrani

Brucellosis remains an important zoonotic disease in southern Saudi Arabia; however, community-level knowledge, risk-related practices, and information pathways in Najran City are insufficiently characterized. This study assessed brucellosis-related...

(This article belongs to the Special Issue Advances in Brucella Infections)
  • Brief Report
  • Open Access
616 Views
15 Pages

Schistosoma japonicum Worms Alter the miRNA Expression Profile of Hepatic Stellate Cells with Potential Implications for Liver Fibrosis and Hepatocellular Carcinoma

  • Haoran Zhong,
  • Bowen Dong,
  • Danlin Zhu,
  • Ruiting Zhang,
  • Yuanzhao Sun,
  • Junhan Xiong,
  • Liu Gao,
  • Ke Lu,
  • Hao Li and
  • Yamei Jin
  • + 2 authors

Although schistosome eggs are widely recognized as the principal drivers of hepatic granulomatous inflammation and fibrosis, the independent effects of adult worms may be masked by strong egg antigen-mediated responses. This study aimed to investigat...

(This article belongs to the Special Issue Research Advances and New Perspectives on Helminthic Diseases)
  • Article
  • Open Access
1 Citations
1,140 Views
20 Pages

Residual Human Intestinal Nematode Infections Following Discontinuation of Mass Drug Administration in a Rural South Asian Setting: Implications for Deworming Surveillance

  • Nalini Jayakody,
  • Catherine A. Gordon,
  • Anjana Silva,
  • Nuwan Wickramasinghe,
  • Susiji Wickramasinghe,
  • Natasha Collinson,
  • Asela Wijayasekara,
  • Chanaka Karunarathne,
  • Nilanthi de Silva and
  • Kosala Weerakoon

Prevalence of soil-transmitted helminth (STH) infections in Sri Lanka has declined from 73.3% in 1954 to <1% in 2017, leading to revised deworming policies and discontinuation of routine deworming in three districts, including Anuradhapura, in 201...

(This article belongs to the Section Neglected and Emerging Tropical Diseases)
  • Article
  • Open Access
785 Views
16 Pages

Localization of the Complement C1q-Binding Site on Echinococcus multilocularis Calreticulin Identified by Peptide Mapping

  • Yinghui Song,
  • Meng Xia,
  • Haoran Zong,
  • Wenjie Dong,
  • Qiang Wang,
  • Qin Yang,
  • Bin Zhan,
  • Yanhai Wang and
  • Limei Zhao

Alveolar echinococcosis is a life-threatening zoonotic parasitic disease caused by infection of Echinococcus multilocularis larvae. To survive within the host’s immune milieu, E. multilocularis has evolved sophisticated immune evasion strategie...

(This article belongs to the Special Issue Research Advances and New Perspectives on Helminthic Diseases)
  • Brief Report
  • Open Access
921 Views
9 Pages

High Positivity Rate for Leptospira Infection in Symptomatic Urban Owned Dogs in Guayaquil, Ecuador

  • Solon Alberto Orlando,
  • Naomi Mora Jaramillo,
  • Ariana Montenegro Pesántez,
  • Melissa Joseth Carvajal-Capa,
  • Jose Julián Zuñiga-Velarde,
  • Silvia Tafur and
  • Miguel Angel Garcia-Bereguiain

Leptospirosis is a zoonotic disease caused by spirochete bacteria of the genus Leptospira, with a wide global distribution. In Ecuador, leptospirosis is endemic, particularly in low-resource tropical areas, and multiple animal reservoirs have been id...

(This article belongs to the Special Issue Leptospirosis and One Health)
  • Article
  • Open Access
895 Views
26 Pages

Zoonotic Spillover of a Canine-like Rotavirus A G3P[3] Strain in a Brazilian Child

  • Vanessa Cristina Martins Silva,
  • Lais Sampaio Azevedo,
  • Raquel Guiducci and
  • Adriana Luchs

Rotavirus A (RVA) G3P[3] genotype is widely reported in dogs and less frequently in cats, with only sporadic human cases worldwide. All reported human infections have occurred in children, suggesting increased susceptibility likely linked to close co...

(This article belongs to the Special Issue Viral Enteropathogens in Pediatric Populations)
  • Article
  • Open Access
1 Citations
1,086 Views
14 Pages

Anthropophagy and Ecological Bridges: Blood-Meal Patterns of Invasive Aedes albopictus (Skuse, 1894) and Native Aedes aegypti Linnaeus, 1762 and Their Implications for Arbovirus Emergence in Central Africa

  • Armel N. Tedjou,
  • Christophe R. Keumeni,
  • Aurélie P. Yougang,
  • Flobert Njiokou,
  • Jo Lines,
  • Sian E. Clarke,
  • Charles S. Wondji and
  • Basile Kamgang

Aedes (Ae.) aegypti and Ae. albopictus are important vectors of arboviruses. Yet their blood-feeding pattern remains poorly characterised in Africa, including Cameroon. In this study, we characterised the blood-meal sources in both species collected...

(This article belongs to the Topic Vector-Borne Disease Spatial Epidemiology, Disease Ecology, and Zoonoses)
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Trop. Med. Infect. Dis. - ISSN 2414-6366