Irrigation plays a crucial role in the success of root canal treatment; however, currently, no standardized irrigation protocols exist, particularly regarding the optimal sequence for smear layer removal. This systematic review aimed to determine whi...
Background: Adult patients with a thin buccal cortical plate and fragile periodontal phenotype are at high risk of dehiscence, fenestration and recession during transverse orthodontic expansion. Conventional mechanics often create a cervical compress...
Objective: To evaluate the clinical success outcomes and risk factors associated with dental implants placed with simultaneous bone augmentation in a large-scale, real-world cohort. Methods: A retrospective analysis was conducted on 158,824 implants,...
Periodontal disease represents a major global concern characterized by chronic biofilm-driven inflammation, excessive oxidative stress, progressive tissue destruction, and impaired regenerative capacity. Beyond conventional antimicrobial approaches,...
Recent advances in biomaterials, immunomodulation, stem cell therapy, and biofabrication are reshaping maxillofacial surgery, shifting reconstruction paradigms toward biologically integrated and patient-specific tissue regeneration. This review provi...
Small-diameter synthetic grafts often fail from thrombosis, intimal hyperplasia, and compliance mismatch, highlighting the need for alternatives that better support endothelialization and remodeling. Here, we evaluated multilayer plant-based vascular...
Cutaneous leishmaniasis is a zoonotic disease caused by Leishmania parasites and leads to chronic, non-healing skin lesions. Although current drugs can control the disease, their use is limited by systemic side effects, low efficacy, and inadequate l...
Three-dimensional biomaterial scaffolds with controlled geometry and surface nanoarchitecture are essential for advancing polymer processing strategies in tissue engineering. Conventional electrospinning generates nanofibrous structures but has limit...
Allomelanin is a natural class of melanin found mainly in fungi and derived from nitrogen-free precursors such as 1,8-dihydroxynaphthalene (1,8-DHN). Despite its biological relevance, allomelanin remains significantly less explored than other synthet...
Skin cancer is among the most common malignancies worldwide, posing a significant societal burden due to its increasing incidence and its limited responsiveness to conventional topical therapies. Treatment is challenged by the presence of the skin ba...
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