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Endometriosis: Diagnosis and Treatment

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Obstetrics & Gynecology".

Deadline for manuscript submissions: 20 January 2026 | Viewed by 313

Special Issue Editors


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Guest Editor
Camran Nezhat Institute, Center for Special Minimally Invasive and Robotic Surgery, Woodside, CA 94061, USA
Interests: endometriosis; infertility; fibroids; adenomyosis; MIS; reproductive surgery; robotic surgery
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Nezhat Medical Center, Atlanta Center for Special Minimally Invasive Surgery and Reproductive Medicine, Atlanta, GA 30342, USA
Interests: minimally invasive surgeon; endometriosis; laparoscopy; robotic techniques
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Endometriosis is a chronic, often debilitating condition that affects an estimated 400 million–1 billion individuals globally. Despite its high prevalence and significant impact on quality of life, diagnosis and treatment remain complex and frequently delayed. This Special Issue aims to bring together leading research and clinical insights concerning the diagnosis and treatment of endometriosis, with a focus on advancing timely, accurate diagnostic methods, evidence-based therapeutic strategies, and multidisciplinary approaches to care.

We invite original research articles, reviews, clinical studies, and case reports that explore innovative diagnostic tools (including imaging and biomarker development), medical and surgical treatment modalities, long-term management strategies, fertility preservation, and the role of artificial intelligence and omics in personalized care. Submissions addressing disparities in access to care and quality of life outcomes are also encouraged.

By assembling a comprehensive body of work on endometriosis, this Special Issue seeks to foster collaboration across specialties, promote standardization of care, and ultimately improve outcomes for individuals affected by this complex disease.

Prof. Dr. Camran R. Nezhat
Dr. Ceana Nezhat
Guest Editors

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Keywords

  • endometriosis
  • diagnosis
  • video laparoscopy with and without robotic assistance
  • chronic pelvic pain
  • fertility preservation
  • minimally invasive surgery
  • biomarkers
  • artificial intelligence in endometriosis, adenomyosis, and adenomyoma care
  • multidisciplinary care
  • personalized medicine

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Published Papers (1 paper)

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Research

8 pages, 565 KiB  
Article
Diagnostic Tools for Endometriosis in Poland: A Comparative Assessment of Reliability and Out-of-Pocket Costs
by Anna Rogalska and Katarzyna Brukało
J. Clin. Med. 2025, 14(14), 4935; https://doi.org/10.3390/jcm14144935 - 11 Jul 2025
Viewed by 220
Abstract
Objectives: This study aimed to assess the availability, diagnostic reliability, and out-of-pocket costs of endometriosis diagnostic tools available on the private healthcare market in Poland. Methods: A desk-based analysis was conducted from a patient perspective to identify commercially available diagnostic tests for endometriosis [...] Read more.
Objectives: This study aimed to assess the availability, diagnostic reliability, and out-of-pocket costs of endometriosis diagnostic tools available on the private healthcare market in Poland. Methods: A desk-based analysis was conducted from a patient perspective to identify commercially available diagnostic tests for endometriosis in Poland. Data were collected in September 2024 using relevant keywords to simulate a patient search process. Identified tests were evaluated for their compliance with the 2022 European Society of Human Reproduction and Embryology (ESHRE) guidelines. Key parameters, including sensitivity, specificity, and associated costs, were assessed based on the available literature. Out-of-pocket costs were compared between the private and public healthcare sectors. Results: Five diagnostic methods were identified in the private healthcare market: two imaging techniques (transvaginal ultrasound, magnetic resonance imaging) and three blood-based tests. None of the blood-based tests demonstrated sensitivity or specificity above 90%. Imaging techniques met this criterion. The cost of blood tests ranged from EUR 21.1 to EUR 467.77. The average private-sector cost for transvaginal ultrasound was EUR 111.64, representing a 482.6% increase compared to the public sector. Magnetic resonance imaging cost EUR 122.89 in the private sector, a 148.64% increase. Conclusions: The private Polish healthcare market lacks non-invasive diagnostic tests for endometriosis that achieve high reliability based on large study samples. Imaging tests, while reliable, pose significant financial barriers when accessed privately. Enhanced public access and clearer patient guidance are required to ensure timely and effective diagnosis. Full article
(This article belongs to the Special Issue Endometriosis: Diagnosis and Treatment)
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