Neuroimmunology in Neurological Disorders: Clinical Diagnosis and Treatment
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".
Deadline for manuscript submissions: 20 March 2027 | Viewed by 343
Editors
2. Department of Physiology, Medical School of National and Kapodistrian University of Athens, Mikras Asias 75, 115 23 Athens, Greece
3. Immunogenetics Laboratory, 1st Department of Neurology, Medical School of National and Kapodistrian University of Athens, Aeginition Hospital, Vas. Sophias, 74, 115 27 Athens, Greece
Interests: multiple sclerosis; neuroimmunology; autoimmune disease; nervous system autoimmune disease
Interests: clinical immunology; immunogenetics; neurology; multiple sclerosis; demyelinating diseases; autoimmunity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neuroimmunology has emerged as a cornerstone in understanding the pathogenesis and clinical progression of diverse neurological and neurosurgical disorders. Increasing evidence demonstrates that inflammatory processes within the central nervous system are not merely reactive, but actively drive neuronal dysfunction, blood–brain barrier disruption, and disease trajectory. Conditions such as Parkinson’s disease, multiple sclerosis, stroke, traumatic brain injury, and hydrocephalus are increasingly viewed through the lens of neuroimmune signaling, which highlights the complex interplay of aging, sex-specific responses, and peripheral–central immune crosstalk.
Driven by breakthroughs in biomarker discovery, advanced neuroimaging, and translational research, the clinical management of neuroimmune disorders is undergoing rapid transformation. There is a pressing need to advance diagnostic precision and to develop targeted immunomodulatory therapies that promote the resolution of pathological inflammation while restoring neuroimmune homeostasis.
This Special Issue aims to bridge fundamental neuroimmune mechanisms with clinical practice. We welcome original research articles and reviews addressing, but not limited to, the following topics:
- Clinical biomarkers and imaging for early diagnosis and prognosis;
- Sex- and age-related neuroimmune variations in disease progression;
- Peripheral–central immune interactions and systemic inflammatory mechanisms;
- Novel immunomodulatory and disease-modifying therapeutic strategies;
- Clinical management of neuroinflammation across acute and chronic disorders;
- Translation of preclinical neuroimmunology into precision patient care.
We look forward to receiving your contributions.
Dr. Charalampos Skarlis
Dr. Maria Anagnostouli
Dr. Evangelia Liouta
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Publisher's Notice
Following discussions between the JCM Editorial Office and the Guest Editor team, the Special Issue description has been revised. This change has been approved by the journal Editorial Board, and the Special Issue website has been updated accordingly on 10 August 2026. The Special Issue will continue to be handled by the Guest Editor team in accordance with MDPI’s Special Issue and editorial policies.
Keywords
- neuroimmunology
- neuroinflammation
- neurodegenerative diseases
- Parkinson’s disease
- multiple sclerosis
- CNS autoimmune disease
- biomarkers
- immunomodulatory therapy
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