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From Acute Injury to Personalized Prevention—Developing Modern Strategies
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From Acute Injury to Personalized Prevention—Developing Modern Strategies

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 10 January 2026 | Viewed by 735

Special Issue Editors

Dr. Markus Gesslein

E-Mail Website
Guest Editor
Department of Orthopedics and Traumatology, Paracelsus Medical University, Breslauer Strasse 201, 90471 Nuremberg, Germany
Interests: arthroscopy; sports injuries; knee surgery; shoulder fracture; septic arthritis; ACL surgery; rotator cuff injuries; concussion
Special Issues, Collections and Topics in MDPI journals
Dr. Eduard Kurz

E-Mail Website
Guest Editor
Department of Orthopedic and Trauma Surgery, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Str. 40, 06120 Halle (Saale), Germany
Interests: rehabilitation; neuromuscular control; biomechanics; return to sport
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, the field of orthopedics has witnessed significant advancements in understanding and managing musculoskeletal injuries, particularly in the context of shifting paradigms from reactive treatment to proactive care. This Special Issue aims to explore the interplay between acute injury management and personalized preventive measures. With the increasing prevalence of sports-related injuries and the growing demands of an aging population, it is critical that we elucidate tailored approaches in orthopedics and traumatology care. This collection of research articles and reviews aims to highlight innovative methodologies, evidence-based practices, and novel technologies that are reshaping how musculoskeletal specialists address both the immediate consequences of acute injuries and long-term strategies for preventing their recurrence. Through interdisciplinary collaborations and a fusion of clinical insights with cutting-edge research, we aspire to advance the discourse on optimizing patient outcomes and enhancing the quality of life of individuals at risk of musculoskeletal disorders.

You may choose our Joint Special Issue in JPM.

Dr. Markus Gesslein
Dr. Eduard Kurz
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • orthopedics
  • acute injury
  • personalized prevention
  • innovative methodologies
  • musculoskeletal disorders
  • musculoskeletal injury
  • conservative therapy
  • functional testing
  • intervention

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Published Papers (1 paper)

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19 pages, 767 KB  
Systematic Review
Redefining Pediatric SCIWORA: A Systematic Review of the Literature on Clinical Patterns, Imaging Profiles, and Management Insights
by Davide Palombi, Marco Galeazzi, Paolo Brigato, Sergio De Salvatore, Timothée De Saint Denis, Luca Massimi, Gianpiero Tamburrini and Leonardo Oggiano
J. Clin. Med. 2025, 14(17), 6338; https://doi.org/10.3390/jcm14176338 - 8 Sep 2025
Viewed by 488
Abstract
Objectives: Among the spectrum of spinal injuries, Spinal Cord Injury Without Radiographic Abnormality (SCIWORA) occupies a unique and challenging position. SCIWORA presents diagnostic and therapeutic challenges due to its broad clinical and radiological heterogeneity. While most children recover favorably with conservative treatment, a [...] Read more.
Objectives: Among the spectrum of spinal injuries, Spinal Cord Injury Without Radiographic Abnormality (SCIWORA) occupies a unique and challenging position. SCIWORA presents diagnostic and therapeutic challenges due to its broad clinical and radiological heterogeneity. While most children recover favorably with conservative treatment, a subset may require surgery based on imaging findings. The findings underscore the need for standardized diagnostic criteria, MRI-based classification systems, and evidence-based treatment algorithms to improve consistency in care and long-term neurological outcomes. Methods: A systematic search of PubMed, Cochrane, Scopus, and Embase databases was performed through June 2025 following PRISMA guidelines. Inclusion criteria encompassed studies of pediatric SCIWORA (age < 18 years) reporting demographics, clinical and radiological features, management, and outcomes. Results: Sixty studies encompassing a total of 848 pediatric patients were included. The mean patient age was 9.33 years (±2.52), with a slight male predominance. The most common trauma mechanisms were road traffic accidents (40.3%), sports injuries (22%), and falls (18.8%). MRI findings were available in 399 cases: 46% had intraneural lesions (Type IIb), 39% showed no abnormality on MRI (Type I, or “real SCIWORA”), 9% had combined lesions (Type IIc), and 6% had extraneural abnormalities (Type IIa). Neurological severity at presentation was primarily ASIA Grade A (46.25%), but follow-up data showed substantial improvement, with ASIA E (normal function) increasing to 49.78%. Overall, 66.2% of patients experienced neurological improvement, while 33.8% remained stable. Conservative treatment was employed in 95.41% of cases. Only 4.59% underwent surgery, which was typically reserved for MRI-positive lesions demonstrating spinal instability or compression. Conclusions: Pediatric SCIWORA remains an uncommon but potentially devastating injury, with an outcome highly dependent on MRI findings and initial neurological status. This systematic review aims to clarify the contemporary understanding of pediatric SCIWORA, delineating “real” SCIWORA from other SCIWORA-like entities, and synthesizing the latest evidence regarding epidemiology, mechanisms, clinical presentation, MRI findings, and management in children. Full article
(This article belongs to the Special Issue From Acute Injury to Personalized Prevention—Developing Modern Strategies)
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