Macular Diseases: From Diagnosis to Treatment
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".
Deadline for manuscript submissions: 22 July 2026 | Viewed by 1404
Special Issue Editor
2. Faculty of Medicine, University of Southampton, Southampton SO17 1BJ, UK
Interests: age-related macular degeneration; retinal vascular diseases; intraocular tumours; retinal imaging
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Macular diseases, including age-related macular degeneration (AMD), diabetic macular edema (DME), and macular holes, are major contributors to central vision loss, especially in older adults. Diagnosis relies on advanced imaging techniques such as optical coherence tomography (OCT) and fluorescein angiography, which allow clinicians to detect retinal abnormalities with high precision. Although early detection methods have improved, many patients are still diagnosed in the later stages of disease progression. Current treatment strategies—primarily anti-VEGF injections, corticosteroids, and laser therapy—can slow vision loss but often require frequent administration and show variable effectiveness. Surgical options exist for specific cases like macular holes, but overall treatment outcomes remain suboptimal. Ongoing research is exploring innovative approaches such as gene therapy, stem cell treatments, and long-acting drug delivery systems to address these limitations. Key challenges in the field include a deeper understanding of disease mechanisms, identifying predictive biomarkers, and enhancing access to timely diagnosis and care. Addressing these issues is crucial for improving patient outcomes and reducing the global impact of macular diseases.
Dr. Gabriella De Salvo
Guest Editor
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Keywords
- age-related macular degeneration
- retinal vascular diseases
- intraocular tumours
- retinal imaging
- OCT
- OCT angiography
- anti-VEGF
- laser therapy
- macular surgery
- gene therapy
- biomarkers
- progression
- intravitreal injections
- biomarkers
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